Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.1001 | 0.7106 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0169 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1001 | 0.7106 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0169 | 0 | 0.5 |
Onchocerca volvulus | 0.0169 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1001 | 0.7106 | 0.7106 |
Onchocerca volvulus | 0.0169 | 0 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0169 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.1001 | 0.7106 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1001 | 0.7106 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1001 | 0.7106 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1001 | 0.7106 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1001 | 0.7106 | 1 |
Onchocerca volvulus | 0.0169 | 0 | 0.5 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0169 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1001 | 0.7106 | 1 |
Onchocerca volvulus | 0.0169 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.1001 | 0.7106 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0169 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0169 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1001 | 0.7106 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1001 | 0.7106 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1001 | 0.7106 | 1 |
Onchocerca volvulus | 0.0169 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.