Detailed information for compound 805618

Basic information

Technical information
  • TDR Targets ID: 805618
  • Name: 1-(4-ethylphenyl)-4-(4-fluoro-3-methoxyphenyl )sulfonylpiperazine
  • MW: 378.461 | Formula: C19H23FN2O3S
  • H donors: 0 H acceptors: 2 LogP: 3.53 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1ccc(c(c1)OC)F
  • InChi: 1S/C19H23FN2O3S/c1-3-15-4-6-16(7-5-15)21-10-12-22(13-11-21)26(23,24)17-8-9-18(20)19(14-17)25-2/h4-9,14H,3,10-13H2,1-2H3
  • InChiKey: OUWJTOBCGZJYFQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-ethylphenyl)-4-(4-fluoro-3-methoxy-phenyl)sulfonyl-piperazine
  • Piperazine, 1-(4-ethylphenyl)-4-(4-fluoro-3-methoxybenzenesulfonyl)-
  • A3414/0144830
  • ZINC01421224

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CYP4Cod1 0.002 0.0016 0.0016
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0021 0.0021 0.0467
Loa Loa (eye worm) hypothetical protein 0.0058 0.0165 0.0165
Onchocerca volvulus 0.0168 0.0597 0.7013
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0016 0.0358
Leishmania major proteasome alpha 2 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Schistosoma mansoni notch 0.0022 0.0024 0.0104
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0001 0.0008
Echinococcus multilocularis proteasome (prosome, macropain) 0.0085 0.0271 0.0883
Brugia malayi beta-lactamase family protein 0.0036 0.0078 0.0078
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.004 0.0887
Brugia malayi Kringle domain containing protein 0.0045 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0811 0.3106 1
Loa Loa (eye worm) calpain 0.0102 0.0339 0.0339
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0021 0.0021 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Leishmania major hypothetical protein, unknown function 0.0031 0.0059 0.1331
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0102 0.0339 0.7589
Onchocerca volvulus Prolyl endopeptidase homolog 0.013 0.0447 0.5245
Echinococcus multilocularis fat cadherin tumor suppressor 0.0022 0.0024 0.0079
Onchocerca volvulus 0.0036 0.0078 0.0917
Mycobacterium ulcerans hypothetical protein 0.0036 0.0078 0.0201
Loa Loa (eye worm) hypothetical protein 0.0058 0.0167 0.0167
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0044
Echinococcus multilocularis peroxidasin 0.0168 0.0597 0.1948
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Brugia malayi Proteasome A-type and B-type family protein 0.0021 0.0021 0.0021
Echinococcus multilocularis snurportin 1 0.0617 0.235 0.7661
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0021 0.0021 0.0467
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0021 0.0021 0.0467
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Plasmodium vivax aspartyl protease, putative 0.031 0.115 1
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0021 0.0021 0.0181
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni cathepsin D (A01 family) 0.0481 0.182 0.7745
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0031 0.0059 0.0517
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0021 0.0021 0.0089
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0021 0.0021 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0021 0.0021 0.0181
Onchocerca volvulus 0.0168 0.0597 0.7013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0271 0.0999 0.4252
Leishmania major hypothetical protein, conserved 0.0031 0.0059 0.1331
Brugia malayi Trypsin family protein 0.0113 0.0382 0.0382
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0021 0.0021 0.0467
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0022 0.0024 0.0024
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Trichomonas vaginalis calpain, putative 0.0031 0.0059 0.0698
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0021 0.0021 0.0089
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0031 0.0059 0.0698
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0021 0.0021 0.0021
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0021 0.0021 0.0089
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0126 0.0432 0.1839
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0109 0.0466
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0021 0.0021 0.0467
Entamoeba histolytica protein kinase, putative 0.0072 0.022 0.8125
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0001 0.0033
Brugia malayi Proteasome subunit alpha type 7-1 0.0021 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Echinococcus granulosus neural cadherin 0.0022 0.0024 0.0104
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0058 0.0167 0.0167
Brugia malayi hypothetical protein 0.0234 0.0855 0.0855
Trichomonas vaginalis hypothetical protein 0.0031 0.0059 0.0698
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0021 0.0021 0.0181
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.04 0.04
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0021 0.0021 0.0467
Echinococcus multilocularis protein jagged 1 0.0022 0.0024 0.0079
Leishmania major kinesin, putative 0.0072 0.0219 0.4899
Loa Loa (eye worm) PAS-3 protein 0.0021 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0047 0.0122 0.4518
Brugia malayi GCC2 and GCC3 family protein 0.0022 0.0024 0.0024
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0078 0.0078
Entamoeba histolytica calpain large subunit domain III containing protein 0.0072 0.0219 0.8081
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.0117 0.1017
Echinococcus granulosus flap endonuclease 1 0.0026 0.004 0.0169
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.2575 1 1
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0113 0.0382 0.1626
Schistosoma mansoni calpain C (C02 family) 0.0102 0.0339 0.1443
Plasmodium falciparum plasmepsin III 0.0058 0.0167 0.1449
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0021 0.0021 0.0467
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0201 0.4509
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0021 0.0021 0.0181
Brugia malayi hypothetical protein 0.0058 0.0167 0.0167
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0052 0.0141 0.3158
Schistosoma mansoni calpain-7 (C02 family) 0.0102 0.0339 0.1443
Onchocerca volvulus Notchless protein homolog 0.0021 0.0021 0.0245
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.0855 0.3638
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Echinococcus granulosus calpain 5 0.0102 0.0339 0.1443
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0021 0.0021 0.0467
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0021 0.0021 0.0467
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.004 0.0465
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0031 0.0059 0.1331
Trypanosoma brucei Calpain-like protein 2 0.0031 0.0059 0.1331
Loa Loa (eye worm) proteasome subunit beta type 1 0.0067 0.0201 0.0201
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.009 1
Brugia malayi calpain family protein 1 0.0271 0.0999 0.0999
Schistosoma mansoni Mername-AA248 (C02 family) 0.0102 0.0339 0.1443
Plasmodium vivax proteasome subunit beta type-5, putative 0.0085 0.0271 0.2354
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0165 0.3694
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.009 0.2008
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0105 0.0917
Echinococcus granulosus protein jagged 1 0.0022 0.0024 0.0104
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Trypanosoma brucei calpain, putative 0.0031 0.0059 0.1331
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0116 0.0394 0.1042
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0095 0.0309 0.0309
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0067 0.0201 0.7438
Schistosoma mansoni peroxidasin 0.0168 0.0597 0.2543
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Echinococcus granulosus subfamily T1A non peptidase ue 0.0021 0.0021 0.0089
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0095 0.0309 0.1314
Echinococcus granulosus notch 0.0022 0.0024 0.0104
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0021 0.0021 0.0021
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0021 0.0021 0.077
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0021 0.0021 0.0739
Loa Loa (eye worm) hypothetical protein 0.0271 0.0999 0.0999
Leishmania major proteasome alpha 1 subunit, putative 0.0021 0.0021 0.0467
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0044 0.0109 0.0952
Onchocerca volvulus Dual oxidase homolog 0.0168 0.0597 0.7013
Echinococcus multilocularis lamin dm0 0.0027 0.0046 0.0151
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.004 0.0887
Echinococcus multilocularis calpain 5 0.0102 0.0339 0.1106
Plasmodium falciparum plasmepsin IV 0.0095 0.0309 0.2685
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.009 0.078
Brugia malayi Proteasome subunit alpha type 1 0.0021 0.0021 0.0021
Echinococcus multilocularis neurogenic locus notch protein 4 0.0022 0.0024 0.0079
Brugia malayi Calcium binding EGF domain containing protein 0.0022 0.0024 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0016 0.0001 0.0027
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.0117 0.0381
Trypanosoma brucei cytochrome P450, putative 0.002 0.0016 0.0358
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Echinococcus multilocularis protein jagged 2 0.0022 0.0024 0.0079
Brugia malayi Trypsin family protein 0.0113 0.0382 0.0382
Onchocerca volvulus 0.0058 0.0167 0.1956
Brugia malayi hypothetical protein 0.0168 0.0597 0.0597
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0113 0.0382 0.1245
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0095 0.0309 0.1007
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0617 0.235 1
Entamoeba histolytica calpain family cysteine protease, putative 0.0031 0.0059 0.2195
Echinococcus multilocularis neural cadherin 0.0022 0.0024 0.0079
Brugia malayi proteasome subunit alpha type 3 0.0021 0.0021 0.0021
Echinococcus multilocularis protein jagged 1 0.0022 0.0024 0.0079
Plasmodium vivax aspartyl protease, putative 0.0058 0.0167 0.1449
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0078 0.1749
Toxoplasma gondii prolyl endopeptidase 0.013 0.0447 0.3884
Trichomonas vaginalis calpain, putative 0.0031 0.0059 0.0698
Brugia malayi Pepsin A precursor 0.0058 0.0167 0.0167
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0095 0.0309 0.2685
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0021 0.0021 0.0467
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Echinococcus multilocularis notch 0.0022 0.0024 0.0079
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Plasmodium falciparum plasmepsin IX 0.031 0.115 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Schistosoma mansoni protein kinase 0.0126 0.0432 0.1839
Schistosoma mansoni ap endonuclease 0.0039 0.009 0.0382
Trypanosoma brucei cysteine peptidase, putative 0.0031 0.0059 0.1331
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Echinococcus granulosus calbindin 32 0.0016 0.0001 0.0004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0122 0.1436
Onchocerca volvulus 0.0168 0.0597 0.7013
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0165 0.0538
Onchocerca volvulus Chorion peroxidase homolog 0.0168 0.0597 0.7013
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.009 0.009
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.004 0.0887
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0021 0.0021 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Brugia malayi RNA, U transporter 1 0.0164 0.0581 0.0581
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0078
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0085 0.0271 0.3179
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0021 0.0021 0.0467
Brugia malayi prolyl oligopeptidase family protein 0.013 0.0447 0.0447
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0016 0.0001 0.0027
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0085 0.0271 0.6062
Schistosoma mansoni septate junction protein 0.0022 0.0024 0.0104
Echinococcus multilocularis prolyl endopeptidase 0.013 0.0447 0.1457
Mycobacterium tuberculosis Probable peptidase 0.0052 0.0141 0.0208
Loa Loa (eye worm) hypothetical protein 0.0095 0.0309 0.0309
Echinococcus granulosus proteasome subunit beta t family 0.0021 0.0021 0.0089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0078
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.009 0.5
Brugia malayi proteasome subunit alpha type 1 0.0021 0.0021 0.0021
Onchocerca volvulus 0.0169 0.0599 0.7035
Onchocerca volvulus Peroxidase homolog 0.0168 0.0597 0.7013
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.013 0.0447 1
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0016 0.0001 0.0004
Plasmodium falciparum plasmepsin VII 0.0058 0.0167 0.1449
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0021 0.0021 0.0467
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0067 0.0201 0.0857
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0021 0.0021 0.0467
Onchocerca volvulus Peroxidasin homolog 0.0168 0.0597 0.7013
Echinococcus granulosus proteasome subunit beta type 6 0.0021 0.0021 0.0089
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0031 0.0059 0.0698
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0067 0.0201 0.4509
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0054 0.0231
Leishmania major importin beta-1 subunit, putative 0.0047 0.0122 0.2739
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0078 0.0917
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0022 0.0024 0.0104
Brugia malayi Trypsin family protein 0.0113 0.0382 0.0382
Onchocerca volvulus Neurogenic locus notch homolog 0.0022 0.0024 0.0286
Schistosoma mansoni ran 0.0043 0.0105 0.0449
Loa Loa (eye worm) hypothetical protein 0.0045 0.0117 0.0117
Echinococcus granulosus fibropellin Ia 0.0022 0.0024 0.0104
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0113 0.0382 0.0382
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0031 0.0059 0.0698
Echinococcus granulosus Proteasome subunit alpha type 7 0.0021 0.0021 0.0089
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0031 0.0059 0.0698
Echinococcus granulosus calcium uptake protein 1 0.0016 0.0001 0.0004
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0044 0.0109 0.0952
Trypanosoma brucei calpain-like protein, putative 0.0102 0.0339 0.7589
Entamoeba histolytica Flap nuclease, putative 0.0026 0.004 0.1462
Echinococcus granulosus calpain A 0.0287 0.1061 0.4514
Toxoplasma gondii aspartyl protease ASP3 0.031 0.115 1
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Trypanosoma cruzi kinesin, putative 0.0072 0.0219 0.4899
Echinococcus granulosus protein jagged 1 0.0022 0.0024 0.0104
Loa Loa (eye worm) hypothetical protein 0.0125 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0078
Onchocerca volvulus 0.0022 0.0024 0.0286
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Leishmania major proteasome alpha 3 subunit, putative 0.0021 0.0021 0.0467
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0021 0.0021 0.0068
Plasmodium falciparum plasmepsin X 0.031 0.115 1
Echinococcus granulosus proteasome subunit alpha type 2 0.0021 0.0021 0.0089
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0111 0.0372 0.0372
Brugia malayi Cadherin domain containing protein 0.0022 0.0024 0.0024
Plasmodium falciparum plasmepsin V 0.0174 0.0618 0.5372
Brugia malayi beta-lactamase family protein 0.0036 0.0078 0.0078
Brugia malayi Muscle positioning protein 4 0.0022 0.0024 0.0024
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.013 0.0447 0.1901
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0078 0.0917
Toxoplasma gondii EGF family domain-containing protein 0.0022 0.0024 0.0212
Giardia lamblia Proteasome subunit beta type 1 0.0067 0.0201 0.7429
Leishmania major proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0052 0.0141 0.3158
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0021 0.0021 0.077
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0021 0.0021 0.077
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0109 0.1285
Plasmodium vivax proteasome subunit beta type-6, putative 0.0021 0.0021 0.0181
Loa Loa (eye worm) proteasome subunit beta type 3 0.0021 0.0021 0.0021
Leishmania major proteasome alpha 1 subunit, putative 0.0021 0.0021 0.0467
Brugia malayi Proteasome A-type and B-type family protein 0.0085 0.0271 0.0271
Brugia malayi Protein kinase domain containing protein 0.0045 0.0117 0.0117
Brugia malayi EF hand family protein 0.0016 0.0001 0.0001
Schistosoma mansoni lamin 0.0027 0.0046 0.0198
Brugia malayi notch-like transmembrane receptor 0.0022 0.0024 0.0024
Leishmania major GTP-binding protein, putative 0.0043 0.0105 0.236
Plasmodium vivax importin-beta 2, putative 0.0058 0.0165 0.1435
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0021 0.0021 0.0089
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0067 0.0201 0.0857
Leishmania major calpain family cysteine protease-like protein 0.0031 0.0059 0.1331
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Echinococcus granulosus protein jagged 2 0.0022 0.0024 0.0104
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Schistosoma mansoni hypothetical protein 0.0048 0.0126 0.0536
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0021 0.0021 0.0467
Toxoplasma gondii calcium-dependent protein kinase 0.0016 0.0002 0.0018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.0339 0.7589
Echinococcus multilocularis calpain family protein 1, d 0.02 0.0719 0.2346
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0085 0.0271 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0741 0.0741
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0105 0.236
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Loa Loa (eye worm) proteasome subunit beta type 2 0.0044 0.0109 0.0109
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0052 0.0141 0.3158
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni ap endonuclease 0.0039 0.009 0.0382
Leishmania major hypothetical protein, conserved 0.0045 0.0117 0.2618
Onchocerca volvulus 0.0113 0.0382 0.4484
Echinococcus multilocularis calcium uptake protein 1 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0021 0.0021 0.0467
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0021 0.0021 0.077
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0031 0.0059 0.1331
Plasmodium vivax proteasome subunit beta type-2, putative 0.0044 0.0109 0.0952
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0054 0.0472
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0054 0.0231
Loa Loa (eye worm) hypothetical protein 0.013 0.0447 0.0447
Onchocerca volvulus 0.0045 0.0117 0.1373
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.004 0.004
Brugia malayi Peroxidasin 0.0168 0.0597 0.0597
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Toxoplasma gondii aspartyl protease ASP1 0.0095 0.0309 0.2685
Giardia lamblia 20S proteasome alpha subunit 7 0.0021 0.0021 0.0739
Echinococcus multilocularis proteasome subunit alpha type 6 0.0021 0.0021 0.0068
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0021 0.0021 0.0021
Trypanosoma cruzi kinesin, putative 0.0072 0.0219 0.4899
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.009 0.0239
Echinococcus granulosus enteropeptidase 0.0113 0.0382 0.1626
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0021 0.0021 0.0181
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Echinococcus multilocularis calpain 0.0102 0.0339 0.1106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0054 0.0231
Trypanosoma cruzi oligopeptidase b 0.0052 0.0141 0.3158
Brugia malayi proteasome subunit alpha type 2 0.0021 0.0021 0.0021
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0021 0.0021 0.0089
Schistosoma mansoni cell polarity protein 0.0022 0.0024 0.0104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0046
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0021 0.0021 0.0181
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0078 0.0333
Leishmania major proteasome beta-1 subunit, putative 0.0021 0.0021 0.0467
Onchocerca volvulus 0.0036 0.0078 0.0917
Brugia malayi Proteasome A-type and B-type family protein 0.0021 0.0021 0.0021
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0085 0.0271 0.1153
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0021 0.0021 0.0467
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0078 0.0917
Leishmania major hypothetical protein, conserved 0.0016 0.0001 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Leishmania major proteasome beta 2 subunit, putative 0.0021 0.0021 0.0467
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.005 0.0213
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0044 0.0109 0.4043
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0021 0.0021 0.0089
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0021 0.0021 0.0467
Brugia malayi Flap endonuclease-1 0.0026 0.004 0.004
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0021 0.0021 0.077
Loa Loa (eye worm) hypothetical protein 0.0058 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0078
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0597 0.0597
Echinococcus multilocularis calpain 7 (C02 family) 0.0102 0.0339 0.1106
Brugia malayi proteasome subunit alpha type 6 0.0021 0.0021 0.0021
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Echinococcus multilocularis lamin 0.0027 0.0046 0.0151
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0287 0.106 0.3456
Giardia lamblia Proteasome subunit beta type 3 0.0021 0.0021 0.0739
Onchocerca volvulus 0.0113 0.0382 0.4484
Giardia lamblia 20S proteasome alpha subunit 1 0.0021 0.0021 0.0739
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.013 0.0447 0.1901
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0095 0.0309 0.3625
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0811 0.3106 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0078 0.0078
Mycobacterium ulcerans beta-lactamase 0.0036 0.0078 0.0201
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0021 0.0021 0.0181
Leishmania major hypothetical protein, conserved 0.0036 0.0078 0.1749
Onchocerca volvulus 0.0027 0.0046 0.0545
Onchocerca volvulus 0.0022 0.0024 0.0286
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0105 0.236
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0046 0.0046
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0044 0.0109 0.0357
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0105 0.0917
Echinococcus multilocularis calpain A 0.0287 0.1061 0.3459
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Echinococcus granulosus neurogenic locus notch protein 0.0022 0.0024 0.0104
Giardia lamblia High cysteine protein 0.0022 0.0024 0.0869
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0021 0.0021 0.0021
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0021 0.0021 0.0739
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.009 0.1053
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Trypanosoma cruzi prolyl endopeptidase 0.013 0.0447 1
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0021 0.0021 0.0089
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0078 0.0201
Echinococcus multilocularis proteasome subunit beta type 6 0.0021 0.0021 0.0068
Schistosoma mansoni memapsin-2 (A01 family) 0.0058 0.0167 0.0709
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0021 0.0021 0.077
Plasmodium falciparum plasmepsin I 0.0095 0.0309 0.2685
Loa Loa (eye worm) Notch2 0.0022 0.0024 0.0024
Plasmodium falciparum plasmepsin II 0.0095 0.0309 0.2685
Onchocerca volvulus Huntingtin homolog 0.0125 0.0426 0.5002
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0022 0.0024 0.0286
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Echinococcus multilocularis fibropellin Ia 0.0022 0.0024 0.0079
Brugia malayi calpain 7 0.0102 0.0339 0.0339
Brugia malayi Cadherin domain containing protein 0.0022 0.0024 0.0024
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0597 0.0597
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0021 0.0021 0.0089
Onchocerca volvulus Peroxidase homolog 0.0168 0.0597 0.7013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Brugia malayi Pre-SET motif family protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) calpain D 0.0031 0.0059 0.0059
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0054 0.0231
Echinococcus granulosus glycoprotein Antigen 5 0.0113 0.0382 0.1626
Schistosoma mansoni cathepsin D (A01 family) 0.0481 0.182 0.7745
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.004 0.0344
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0078 0.0917
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.009 0.078
Toxoplasma gondii proteasome subunit 0.0021 0.0021 0.0181
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0105 0.0449
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0021 0.0021 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0021 0.0021 0.0181
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Echinococcus granulosus calpain 0.0102 0.0339 0.1443
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0016 0.0016
Plasmodium vivax aspartyl proteinase, putative 0.0058 0.0167 0.1449
Echinococcus multilocularis proteasome subunit alpha type 2 0.0021 0.0021 0.0068
Echinococcus granulosus Proteasome subunit alpha beta 0.0021 0.0021 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0059 0.0698
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0031 0.0059 0.1331
Schistosoma mansoni calpain-7 (C02 family) 0.0102 0.0339 0.1443
Echinococcus granulosus delta-like protein 1 0.0022 0.0024 0.0104
Brugia malayi Trypsin-like protease protein 5 0.0113 0.0382 0.0382
Onchocerca volvulus 0.0113 0.0382 0.4484
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0021 0.0021 0.0068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trypanosoma cruzi 20S proteasome subunit 0.0044 0.0109 0.2451
Trypanosoma brucei oligopeptidase b 0.0052 0.0141 0.3158
Trichomonas vaginalis set domain proteins, putative 0.0234 0.0852 1
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0021 0.0021 0.0467
Toxoplasma gondii aspartyl protease 0.0058 0.0167 0.1449
Onchocerca volvulus 0.0058 0.0167 0.1956
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0044 0.0109 0.2451
Toxoplasma gondii kringle domain-containing protein 0.0045 0.0117 0.1017
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.04 0.04
Mycobacterium ulcerans proteasome PrcB 0.0085 0.0271 0.0825
Brugia malayi Pre-SET motif family protein 0.0205 0.0741 0.0741
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.0855 0.2787
Brugia malayi hypothetical protein 0.0113 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Plasmodium falciparum proteasome subunit beta type-4 0.0021 0.0021 0.0181
Onchocerca volvulus Peroxidasin homolog 0.0168 0.0597 0.7013
Plasmodium vivax calpain, putative 0.0102 0.0339 0.2947
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0105 0.0105
Schistosoma mansoni calpain-2 (C02 family) 0.0031 0.0059 0.0253
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0021 0.0021 0.0068
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.0339 0.7589
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0113 0.0382 0.1626
Schistosoma mansoni calpain (C02 family) 0.0102 0.0339 0.1443
Plasmodium vivax proteasome subunit beta type-7, putative 0.0021 0.0021 0.0181
Trypanosoma brucei calpain-like protein, putative 0.0102 0.0339 0.7589
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0085 0.0271 1
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0021 0.0021 0.0181
Brugia malayi Trypsin family protein 0.0113 0.0382 0.0382
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0016 0.0001 0.002
Brugia malayi Cytochrome P450 family protein 0.0049 0.0132 0.0132
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0078 0.0917
Schistosoma mansoni survival motor neuron protein 0.0048 0.0126 0.0536
Schistosoma mansoni notch 0.0022 0.0024 0.0104
Loa Loa (eye worm) hypothetical protein 0.024 0.0879 0.0879
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.0339 0.7589
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0021 0.0021 0.0181
Toxoplasma gondii ABC1 family protein 0.0036 0.0078 0.0679
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0085 0.0271 0.6062
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0021 0.0021 0.0467
Loa Loa (eye worm) beta-lactamase 0.0036 0.0078 0.0078
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0021 0.0021 0.0021
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0021 0.0021 0.0181
Echinococcus multilocularis Mastin 0.0113 0.0382 0.1245
Brugia malayi Eukaryotic aspartyl protease family protein 0.0058 0.0167 0.0167
Trichomonas vaginalis calpain, putative 0.0031 0.0059 0.0698
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0165 0.3694
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Echinococcus multilocularis neurogenic locus notch protein 0.0022 0.0024 0.0079
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0021 0.0021 0.0181
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0122 0.1436
Echinococcus granulosus prolyl endopeptidase 0.013 0.0447 0.1901
Toxoplasma gondii aspartyl protease ASP5 0.0115 0.0391 0.3395
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Brugia malayi 20S proteasome alpha5 subunit 0.0021 0.0021 0.0021
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0095 0.0309 0.1314
Trypanosoma brucei proteasome alpha 7 subunit 0.0021 0.0021 0.0467
Echinococcus multilocularis calumenin 0.0016 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0021 0.0021 0.077
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0287 0.106 0.4511
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Echinococcus multilocularis neurogenic locus notch protein 0.0022 0.0024 0.0079
Trichomonas vaginalis esterase, putative 0.0036 0.0078 0.0917
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.009 0.0038
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0031 0.0059 0.0698
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.004 0.1434
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0021 0.0021 0.0467
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Leishmania major proteasome beta 3 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni notch 0.0022 0.0024 0.0104
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0287 0.106 0.4511
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0021 0.0021 0.077
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0105 0.3873
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0067 0.0201 0.0657
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0021 0.0021 0.0467
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0021 0.0021 0.0245
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0021 0.0021 0.0021
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0031 0.0059 0.1331
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0021 0.0021 0.0089
Trypanosoma cruzi conserved protein 0.0031 0.0059 0.1331
Schistosoma mansoni hypothetical protein 0.0113 0.0382 0.1626
Brugia malayi MH2 domain containing protein 0.0118 0.04 0.04
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0021 0.0021 0.0467
Echinococcus granulosus calpain A 0.0102 0.0339 0.1443
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0052 0.0141 0.0405
Plasmodium falciparum calpain 0.0031 0.0059 0.0517
Echinococcus granulosus proteasome subunit beta type 7 0.0021 0.0021 0.0089
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0021 0.0021 0.0089
Loa Loa (eye worm) aspartyl protease 6 0.0058 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Brugia malayi Cytochrome P450 family protein 0.002 0.0016 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Brugia malayi intermediate filament protein 0.0027 0.0046 0.0046
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0021 0.0021 0.0068
Trypanosoma brucei calpain-like protein, putative 0.0102 0.0339 0.7589
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0054 0.0231
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0052 0.0141 0.0208
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0031 0.0059 0.0698
Brugia malayi proteasome subunit beta type 3 0.0021 0.0021 0.0021
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0067 0.0201 0.1751
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0021 0.0021 0.0467
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0021 0.0021 0.0467
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0021 0.0021 0.0739
Brugia malayi proteasome subunit beta type 2 0.0044 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Onchocerca volvulus 0.0016 0.0001 0.0011
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0016 0.0001 0.0027
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0021 0.0021 0.0181
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0105 0.0917
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Schistosoma mansoni peroxidasin 0.0168 0.0597 0.2543
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0021 0.0021 0.077
Echinococcus granulosus importin subunit beta 1 0.0058 0.0165 0.0703
Leishmania major proteasome beta 2 subunit, putative 0.0044 0.0109 0.2451
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0046 0.0046
Echinococcus multilocularis musashi 0.0027 0.0046 0.0151
Mycobacterium ulcerans hypothetical protein 0.0113 0.0382 0.1184
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0617 0.235 0.235
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0021 0.0021 0.077
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.1749
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0597 0.0597
Trypanosoma brucei hypothetical protein 0.0031 0.0059 0.1331
Onchocerca volvulus 0.0036 0.0078 0.0917
Echinococcus multilocularis proteasome subunit beta type 7 0.0021 0.0021 0.0068
Plasmodium vivax proteasome subunit beta type-1, putative 0.0067 0.0201 0.1751
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0021 0.0021 0.077
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.0117 0.1017
Echinococcus granulosus lamin 0.0027 0.0046 0.0198
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.009 0.009
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0287 0.106 0.4511
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Toxoplasma gondii calmodulin CAM1 0.0016 0.0001 0.0008
Brugia malayi Blistered cuticle protein 3 0.0168 0.0597 0.0597
Schistosoma mansoni notch 0.0022 0.0024 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0031 0.0059 0.1331
Leishmania major calpain protease-like protein 0.0031 0.0059 0.1331
Echinococcus granulosus lamin dm0 0.0027 0.0046 0.0198
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0054 0.0177
Toxoplasma gondii exonuclease III APE 0.0039 0.009 0.078
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Schistosoma mansoni notch 0.0022 0.0024 0.0104
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0021 0.0021 0.0068
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0021 0.0021 0.0181
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0021 0.0021 0.0467
Echinococcus granulosus slit 2 protein 0.0022 0.0024 0.0104
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0021 0.0021 0.0181
Echinococcus multilocularis hypothetical protein 0.0102 0.0339 0.1106
Onchocerca volvulus 0.0022 0.0024 0.0286
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.009 0.0293
Toxoplasma gondii peptidase, T1 family protein 0.0021 0.0021 0.0181
Trypanosoma brucei kinesin, putative 0.0072 0.0219 0.4899
Trichomonas vaginalis calmodulin, putative 0.0016 0.0001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0021 0.0021 0.0181
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Brugia malayi calpain D 0.0031 0.0059 0.0059
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Giardia lamblia 20S proteasome alpha subunit 4 0.0021 0.0021 0.0739
Trypanosoma brucei proteasome beta 6 subunit 0.0067 0.0201 0.4509
Echinococcus granulosus Mastin 0.0113 0.0382 0.1626
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0021 0.0021 0.077
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0021 0.0021 0.0467
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.009 0.2008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0021 0.0021 0.0181
Echinococcus granulosus protein jagged 2 0.0022 0.0024 0.0104
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1245
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.0339 0.7589
Trypanosoma brucei Calpain-like protein 1.2 0.0031 0.0059 0.1331
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0021 0.0021 0.0181
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0078 0.0201
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0067 0.0201 0.2365
Echinococcus granulosus proteasome subunit alpha type 6 0.0021 0.0021 0.0089
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.0117 0.0498
Onchocerca volvulus Huntingtin homolog 0.0125 0.0426 0.5002
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0021 0.0021 0.077
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Brugia malayi beta-lactamase 0.0036 0.0078 0.0078
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0227 0.0826 0.2471
Entamoeba histolytica Ran family GTPase 0.0043 0.0105 0.3893
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0201 0.4509
Echinococcus multilocularis transmembrane protease serine 3 0.0113 0.0382 0.1245
Loa Loa (eye worm) calpain family protein 1 0.02 0.0719 0.0719
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0046 0.0046
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.009 0.2008
Mycobacterium ulcerans proteasome PrcA 0.0811 0.3106 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trypanosoma brucei proteasome beta 7 subunit 0.0021 0.0021 0.0467
Echinococcus multilocularis neurogenic locus protein delta 0.0022 0.0024 0.0079
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0054 0.0177
Schistosoma mansoni lamin 0.0027 0.0046 0.0198
Echinococcus multilocularis neurogenic locus protein delta 0.0022 0.0024 0.0079
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0021 0.0022 0.0815
Schistosoma mansoni hypothetical protein 0.0031 0.0059 0.0253
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0021 0.0021 0.0089
Echinococcus granulosus peroxidasin 0.0168 0.0597 0.2543
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0021 0.0021 0.0181
Plasmodium vivax proteasome subunit beta type-4, putative 0.0021 0.0021 0.0181
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.009 0.0382
Onchocerca volvulus 0.0234 0.0852 1
Trypanosoma brucei calmodulin, putative 0.0016 0.0001 0.002
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0021 0.0021 0.0245
Schistosoma mansoni hypothetical protein 0.0113 0.0382 0.1626
Trypanosoma brucei Calpain-like protein 1.1 0.0031 0.0059 0.1331
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0021 0.0021 0.0467
Loa Loa (eye worm) programmed cell death protein 6 0.0016 0.0001 0.0001
Loa Loa (eye worm) blistered cuticle protein 3 0.0168 0.0597 0.0597
Brugia malayi hypothetical protein 0.0058 0.0167 0.0167
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.009 0.2008
Giardia lamblia 20S proteasome alpha subunit 2 0.0021 0.0021 0.0739
Plasmodium falciparum plasmepsin VI 0.0095 0.0309 0.2685
Trypanosoma brucei prolyl oligopeptidase, putative 0.0052 0.0141 0.3158
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Plasmodium vivax SET domain protein, putative 0.0029 0.0054 0.0472
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.08 0.3067 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Echinococcus granulosus calpain 7 C02 family 0.0102 0.0339 0.1443
Echinococcus multilocularis slit 2 protein 0.0022 0.0024 0.0079
Plasmodium vivax plasmepsin V, putative 0.0174 0.0618 0.5372
Echinococcus granulosus neurogenic locus notch protein 0.0022 0.0024 0.0104
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0105 0.0344
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0597 0.0597
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0021 0.0021 0.0068
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0021 0.0021 0.0181
Schistosoma mansoni flap endonuclease-1 0.0023 0.003 0.0128
Onchocerca volvulus 0.0022 0.0024 0.0286
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0165 0.1435
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Onchocerca volvulus 0.0027 0.0046 0.0545
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0167 0.0709
Giardia lamblia 20S proteasome alpha subunit 6 0.0021 0.0021 0.0739
Brugia malayi Calcium binding EGF domain containing protein 0.0022 0.0024 0.0024
Plasmodium vivax plasmepsin IV, putative 0.0095 0.0309 0.2685
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Plasmodium falciparum flap endonuclease 1 0.0026 0.004 0.0344
Leishmania major proteasome beta 7 subunit, putative 0.0021 0.0021 0.0467
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0597 0.0597
Giardia lamblia Proteasome subunit beta type 2 0.0044 0.0109 0.4023
Brugia malayi Calcium binding EGF domain containing protein 0.0022 0.0024 0.0024
Echinococcus multilocularis enteropeptidase 0.0113 0.0382 0.1245
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0044 0.0109 0.2451
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.004 0.0344
Brugia malayi hypothetical protein 0.0125 0.0426 0.0426
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Brugia malayi calpain family protein 1 0.0271 0.0999 0.0999
Loa Loa (eye worm) hypothetical protein 0.0031 0.0059 0.0059
Echinococcus granulosus EF hand domain containing family member A2 0.0016 0.0001 0.0004
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0021 0.0021 0.0467
Loa Loa (eye worm) hypothetical protein 0.0234 0.0855 0.0855
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0104
Toxoplasma gondii heat shock protein hslv, putative 0.0021 0.0021 0.0181
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Giardia lamblia 20S proteasome alpha subunit 5 0.0021 0.0021 0.0739
Trypanosoma brucei antigen, putative 0.0102 0.0339 0.7589
Trypanosoma brucei calpain-like protein, putative 0.0102 0.0339 0.7589
Schistosoma mansoni notch 0.0022 0.0024 0.0104
Brugia malayi aspartic protease BmAsp-1, identical 0.0058 0.0167 0.0167
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0111 0.0372 0.0372
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0044 0.0109 0.1285
Echinococcus multilocularis flap endonuclease 1 0.0026 0.004 0.0129
Giardia lamblia 20S proteasome alpha subunit 3 0.0021 0.0021 0.0739
Brugia malayi Importin beta-1 subunit 0.0058 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0021 0.0021 0.0089
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Onchocerca volvulus 0.0022 0.0024 0.0286
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0021 0.0021 0.0089
Toxoplasma gondii proteasome subunit alpha type, putative 0.0021 0.0021 0.0181
Onchocerca volvulus 0.0048 0.0126 0.1479
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0021 0.0021 0.0181
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0021 0.0021 0.0021
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0085 0.0271 0.6062
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Schistosoma mansoni cercarial elastase (S01 family) 0.0113 0.0382 0.1626
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0021 0.0021 0.0467
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0078 0.1749
Onchocerca volvulus Slit protein homolog 0.0022 0.0024 0.0286
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0597 0.0597
Toxoplasma gondii proteasome subunit beta type, putative 0.0085 0.0271 0.2354
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0016 0.0016
Entamoeba histolytica grainin, putative 0.0016 0.0001 0.0033
Schistosoma mansoni hypothetical protein 0.0045 0.0117 0.0498
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0021 0.0021 0.0089
Brugia malayi aspartic protease BmAsp-2, identical 0.0058 0.0167 0.0167
Echinococcus granulosus neurogenic locus notch protein 4 0.0022 0.0024 0.0104
Schistosoma mansoni protein kinase 0.0126 0.0432 0.1839
Echinococcus granulosus proteasome prosome macropain 0.0085 0.0271 0.1153
Brugia malayi Cytochrome P450 family protein 0.002 0.0016 0.0016
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0052 0.0141 0.0208
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.0382 0.1626
Onchocerca volvulus 0.0113 0.0382 0.4484
Trypanosoma brucei calpain, putative 0.0031 0.0059 0.1331
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0021 0.0021 0.077
Echinococcus multilocularis calbindin 32 0.0016 0.0001 0.0003
Schistosoma mansoni ran 0.0043 0.0105 0.0449
Leishmania major proteasome beta 5 subunit, putative 0.0085 0.0271 0.6062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.009 0.329
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0021 0.0021 0.0245
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0021 0.0021 0.0245
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0021 0.0021 0.0467
Plasmodium vivax aspartyl proteinase, putative 0.0095 0.0309 0.2685
Brugia malayi Proteasome A-type and B-type family protein 0.0021 0.0021 0.0021
Echinococcus granulosus transmembrane protease serine 3 0.0113 0.0382 0.1626
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0058 0.0167 0.1449
Brugia malayi proteasome subunit beta type 1 0.0067 0.0201 0.0201
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0117 0.2618
Loa Loa (eye worm) calpain family protein 1 0.0271 0.0999 0.0999
Trypanosoma brucei Calpain-like protein CALP1.3 0.0031 0.0059 0.1331
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0085 0.0271 0.0271
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0044 0.0109 0.0466
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.009 0.1053
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Onchocerca volvulus Putative cubilin 0.0022 0.0024 0.0286
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0052 0.0141 0.3158
Leishmania major protein kinase, putative 0.0016 0.0001 0.0027
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0021 0.0021 0.077
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0122 0.1436
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0031 0.0059 0.1331
Loa Loa (eye worm) hypothetical protein 0.02 0.0719 0.0719
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0021 0.0021 0.0068
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0021 0.0021 0.0068
Plasmodium vivax aspartyl protease, putative 0.031 0.115 1
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0078 0.0679
Onchocerca volvulus 0.0113 0.0382 0.4484
Loa Loa (eye worm) hypothetical protein 0.0125 0.0426 0.0426
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.006 0.0522
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Plasmodium falciparum plasmepsin VIII, putative 0.0058 0.0167 0.1449
Schistosoma mansoni slit 0.0022 0.0024 0.0104
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0021 0.0021 0.0181
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0024
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0021 0.0021 0.0089
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0597 0.0597
Plasmodium falciparum proteasome subunit beta type-5 0.0085 0.0271 0.2354
Trichomonas vaginalis ran, putative 0.0043 0.0105 0.1238
Toxoplasma gondii hypothetical protein 0.0031 0.0059 0.0517
Trypanosoma cruzi oligopeptidase b 0.0052 0.0141 0.3158
Leishmania major cytochrome p450-like protein 0.002 0.0016 0.0358
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0021 0.0021 0.0181
Plasmodium vivax proteasome subunit beta type-3, putative 0.0021 0.0021 0.0181
Brugia malayi calpain 5 0.0072 0.0219 0.0219
Echinococcus granulosus calumenin 0.0016 0.0001 0.0004
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0021 0.0021 0.0089
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0102 0.0339 0.7589
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0021 0.0021 0.0467
Loa Loa (eye worm) notch protein 0.0022 0.0024 0.0024
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.0339 0.7589
Loa Loa (eye worm) hypothetical protein 0.0113 0.0382 0.0382
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0031 0.0059 0.1331
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0078 0.0255
Schistosoma mansoni laminin gamma-3 chain 0.0022 0.0024 0.0104
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0105 0.236
Echinococcus multilocularis EF hand domain containing family member A2 0.0016 0.0001 0.0003
Schistosoma mansoni reticulocalbin 0.0016 0.0001 0.0004
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0067 0.0201 0.1751
Mycobacterium ulcerans lipase LipD 0.0036 0.0078 0.0201
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0122 0.2739
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0126 0.0432 0.1409
Echinococcus granulosus neurogenic locus protein delta 0.0022 0.0024 0.0104
Onchocerca volvulus 0.0113 0.0382 0.4484
Brugia malayi proteasome subunit alpha type 4 0.0021 0.0021 0.0021
Brugia malayi Delta serrate ligand family protein 0.0022 0.0024 0.0024
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.009 0.3313
Brugia malayi Animal haem peroxidase family protein 0.0168 0.0597 0.0597
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0078 0.0333
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0031 0.0059 0.1331
Onchocerca volvulus 0.0029 0.0054 0.0637
Echinococcus granulosus intermediate filament protein 0.0027 0.0046 0.0198
Schistosoma mansoni rab 0.0016 0.00000004812 0.00000020481
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0021 0.0021 0.0181
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0078 0.0333
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0021 0.0021 0.0021
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0021 0.0021 0.0089
Loa Loa (eye worm) hypothetical protein 0.0168 0.0597 0.0597
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0016 0.0358
Plasmodium falciparum importin beta, putative 0.0058 0.0165 0.1435
Schistosoma mansoni importin beta-1 0.0058 0.0165 0.0703
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0085 0.0271 0.0636
Trichomonas vaginalis calcineurin B subunit, putative 0.0016 0.0001 0.0011
Loa Loa (eye worm) calpain 5 0.0072 0.0219 0.0219
Leishmania major proteasome alpha 7 subunit, putative 0.0021 0.0021 0.0467
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0085 0.0271 0.0636
Loa Loa (eye worm) hypothetical protein 0.0169 0.0599 0.0599
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0105 0.0105
Schistosoma mansoni protein kinase 0.0126 0.0432 0.1839
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.0597 0.0597
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0113 0.0382 0.1626
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0021 0.0021 0.0245
Toxoplasma gondii proteasome beta subunit 0.0021 0.0021 0.0181
Leishmania major oligopeptidase b 0.0052 0.0141 0.3158
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.0339 0.7589
Loa Loa (eye worm) hypothetical protein 0.0036 0.0078 0.0078
Toxoplasma gondii proteasome subunit alpha1, putative 0.0021 0.0021 0.0181
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0132 0.0132
Brugia malayi calpain 5 0.0031 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) trypsin family protein 0.0113 0.0382 0.0382
Echinococcus multilocularis glycoprotein Antigen 5 0.0113 0.0382 0.1245
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0117 0.0117
Trypanosoma brucei prolyl endopeptidase 0.013 0.0447 1
Brugia malayi EGF-like domain containing protein 0.0022 0.0024 0.0024
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0044 0.0109 0.0466
Schistosoma mansoni intermediate filament proteins 0.0027 0.0046 0.0198
Echinococcus granulosus snurportin 1 0.0617 0.235 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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