Detailed information for compound 805843

Basic information

Technical information
  • TDR Targets ID: 805843
  • Name: 3-(aminomethyl)-5-tert-butylfuran-2-carboxyli c acid
  • MW: 197.231 | Formula: C10H15NO3
  • H donors: 2 H acceptors: 2 LogP: -0.87 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCc1cc(oc1C(=O)O)C(C)(C)C
  • InChi: 1S/C10H15NO3/c1-10(2,3)7-4-6(5-11)8(14-7)9(12)13/h4H,5,11H2,1-3H3,(H,12,13)
  • InChiKey: KUFIAZNIYKWTCJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(aminomethyl)-5-tert-butyl-furan-2-carboxylic acid
  • 3-(aminomethyl)-5-tert-butyl-2-furancarboxylic acid
  • 3-(aminomethyl)-5-tert-butyl-2-furoic acid
  • A3497/0148287
  • SDCCGMLS-0065276.P001
  • 3-Aminomethyl-5-tert-butyl-furan-2-carboxylic acid
  • BAS 07211771
  • 3-(azaniumylmethyl)-5-tert-butylfuran-2-carboxylate
  • 3-(azaniumylmethyl)-5-tert-butyl-furan-2-carboxylate
  • 3-(ammoniomethyl)-5-tert-butyl-2-furancarboxylate
  • 3-(ammoniomethyl)-5-tert-butyl-2-furoate
  • ZINC04475850

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.004 0.0112 0.0221
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0145 0.0748 0.0748
Schistosoma mansoni hypothetical protein 0.0792 0.4652 0.4652
Loa Loa (eye worm) hypothetical protein 0.0041 0.0121 0.024
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0145 0.0748 0.0748
Brugia malayi bHLH-PAS transcription factor 0.0039 0.011 0.0201
Loa Loa (eye worm) glutaminase 0.029 0.1623 0.3213
Echinococcus granulosus Nuclear hormone receptor HR96 0.0068 0.0286 0.0286
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0068 0.0286 0.0286
Brugia malayi nuclear receptor NHR-67 0.0068 0.0286 0.0523
Toxoplasma gondii hypothetical protein 0.0053 0.0193 0.0904
Onchocerca volvulus 0.0085 0.0387 0.1405
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.042 0.2406 0.4763
Toxoplasma gondii ABC1 family protein 0.0038 0.0103 0.012
Loa Loa (eye worm) hypothetical protein 0.0077 0.0335 0.0664
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.034 0.034
Brugia malayi nuclear hormone receptor 0.0145 0.0748 0.1369
Onchocerca volvulus 0.0068 0.0286 0.1037
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0152 0.0277
Schistosoma mansoni cpg binding protein 0.0118 0.0584 0.0584
Echinococcus multilocularis ecdysone induced protein 78C 0.0145 0.0748 0.0748
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.009 0.0417 0.0417
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0103 0.0205
Schistosoma mansoni lamin 0.0085 0.0387 0.0387
Brugia malayi nuclear hormone receptor family member odr-7 0.0068 0.0286 0.0523
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0039 0.0111 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0213 0.0625
Echinococcus granulosus survival motor neuron protein 1 0.0258 0.1427 0.1427
Entamoeba histolytica serine/threonine protein kinase, putative 0.0089 0.0411 0.2074
Onchocerca volvulus 0.004 0.0115 0.0417
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0013 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0103 0.0255
Loa Loa (eye worm) agrin synaptic family protein 0.0036 0.009 0.0178
Brugia malayi hypothetical protein 0.0258 0.1427 0.2612
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0116 0.0301
Onchocerca volvulus Putative organic anion transporter 0.0053 0.019 0.0691
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0145 0.0748 0.0748
Brugia malayi conserved hypotetical protein 0.0068 0.0286 0.0523
Onchocerca volvulus Bile acid receptor homolog 0.0145 0.0748 0.2715
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0083 0.0374 0.0374
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0116 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.025 0.025
Brugia malayi hypoxia-induced factor 1 0.0164 0.0863 0.1579
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0858 0.5052 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0068 0.0286 0.0286
Echinococcus granulosus glutamate receptor 2 0.0023 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0145 0.0748 0.1369
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0145 0.0748 0.1369
Echinococcus granulosus thyroid hormone receptor alpha 0.0068 0.0286 0.0286
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0036 0.009 0.0164
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0068 0.0286 0.0286
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0039 0.0111 0.5
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0618 0.0618
Brugia malayi Nuclear hormone receptor E75 0.0068 0.0286 0.0523
Schistosoma mansoni hypothetical protein 0.004 0.0115 0.0115
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0145 0.0748 0.1481
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.0813 0.4041
Loa Loa (eye worm) proliferating cell nuclear antigen 0.0204 0.1101 0.218
Brugia malayi serine/threonine-protein kinase plk-2 0.0089 0.0411 0.0752
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.025 0.025
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0083 0.0374 0.0374
Echinococcus multilocularis musashi 0.0085 0.0387 0.0387
Brugia malayi nuclear receptor RXR 0.0077 0.0335 0.0613
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0077 0.0335 0.0335
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Leishmania major cathepsin L-like protease 0.0069 0.0292 0.1076
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0013 0.0013
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0292 0.1076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.025 0.025
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0271 0.1508 0.2985
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0068 0.0286 0.0286
Schistosoma mansoni thyroid hormone receptor 0.0937 0.5528 0.5528
Schistosoma mansoni hypothetical protein 0.009 0.0417 0.0417
Schistosoma mansoni glutaminase 0.029 0.1623 0.1623
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0145 0.0748 0.1369
Schistosoma mansoni agrin 0.0036 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0377
Trypanosoma cruzi polo-like protein kinase, putative 0.0089 0.0411 0.1752
Loa Loa (eye worm) hypothetical protein 0.0258 0.1427 0.2826
Entamoeba histolytica hypothetical protein 0.0077 0.034 0.1574
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0205
Loa Loa (eye worm) steroid hormone receptor 0.0145 0.0748 0.1481
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Echinococcus granulosus single minded 2 0.0039 0.011 0.011
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0135 0.0686 0.4689
Loa Loa (eye worm) hypothetical protein 0.0077 0.0335 0.0664
Plasmodium falciparum proliferating cell nuclear antigen 2 0.0109 0.053 0.4208
Toxoplasma gondii proliferating cell nuclear antigen PCNA2 0.0109 0.053 0.3849
Schistosoma mansoni hypothetical protein 0.0371 0.2109 0.2109
Brugia malayi hypothetical protein 0.0418 0.2395 0.4383
Schistosoma mansoni apoptosis regulator bax 0.009 0.0417 0.0417
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0116 0.0116
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0145 0.0748 0.0748
Plasmodium vivax SET domain protein, putative 0.0062 0.025 0.1464
Brugia malayi nuclear receptor NHR-88 0.0145 0.0748 0.1369
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.025 0.1398
Trypanosoma brucei polo-like protein kinase 0.0089 0.0411 0.1752
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0013 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Echinococcus granulosus lamin 0.0085 0.0387 0.0387
Schistosoma mansoni kinase 0.0045 0.0146 0.0146
Schistosoma mansoni RAR-like nuclear receptor 0.0145 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Onchocerca volvulus 0.0085 0.0387 0.1405
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0145 0.0748 0.1369
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0023 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0077 0.034 0.1574
Schistosoma mansoni nuclear receptor 0.0068 0.0286 0.0286
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.025 0.025
Brugia malayi hypothetical protein 0.0053 0.019 0.0349
Schistosoma mansoni intermediate filament proteins 0.0085 0.0387 0.0387
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0145 0.0748 0.0748
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0116 0.0212
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0145 0.0748 0.0748
Loa Loa (eye worm) nuclear receptor NHR-67 0.0068 0.0286 0.0566
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0145 0.0748 0.0748
Echinococcus granulosus lamin dm0 0.0085 0.0387 0.0387
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0292 0.1076
Brugia malayi nuclear hormone receptor family member nhr-6 0.0068 0.0286 0.0523
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0083 0.0374 0.074
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0377
Onchocerca volvulus 0.0038 0.0103 0.0375
Echinococcus multilocularis survival motor neuron protein 1 0.0258 0.1427 0.1427
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0041 0.0121 0.0121
Brugia malayi Nuclear hormone receptor-like 1 0.0858 0.5052 0.9245
Echinococcus multilocularis expressed protein 0.0036 0.009 0.009
Echinococcus granulosus follistatin 0.0036 0.009 0.009
Brugia malayi ecdysteroid receptor 0.0145 0.0748 0.1369
Schistosoma mansoni hypothetical protein 0.0077 0.034 0.034
Onchocerca volvulus 0.0062 0.025 0.0906
Giardia lamblia Fructose-bisphosphate aldolase 0.0276 0.1537 1
Brugia malayi Pre-SET motif family protein 0.0062 0.025 0.0457
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Loa Loa (eye worm) intermediate filament protein 0.0085 0.0387 0.0766
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0055 0.0203 0.0203
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0618 0.3385
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0193 0.0193
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0135 0.0686 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0013 0.0013
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0036 0.009 0.0164
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0205
Brugia malayi follicle stimulating hormone receptor 0.0271 0.1508 0.276
Chlamydia trachomatis glutamine binding protein 0.0039 0.0111 0.5
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0036 0.009 0.0178
Onchocerca volvulus 0.0477 0.2755 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0103 0.0255
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0377
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0013 0.0013
Brugia malayi nuclear hormone receptor 0.0068 0.0286 0.0523
Brugia malayi sodium-independent organic anion transporter family protein 0.0083 0.0374 0.0684
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0145 0.0748 0.0748
Mycobacterium ulcerans glutaminase 0.029 0.1623 1
Echinococcus multilocularis nmda type glutamate receptor 0.0055 0.0203 0.0203
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0329 0.1858 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0041 0.0121 0.0121
Brugia malayi nuclear receptor RXR 0.0068 0.0286 0.0523
Schistosoma mansoni retinoic acid receptor RXR 0.0145 0.0748 0.0748
Brugia malayi beta-lactamase family protein 0.0038 0.0103 0.0189
Echinococcus granulosus RUN 0.004 0.0115 0.0115
Onchocerca volvulus 0.0083 0.0374 0.1356
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0103 0.0189
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0618 0.0618
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0145 0.0748 0.0748
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0103 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0145 0.0748 0.1369
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0039 0.0111 0.0048
Echinococcus granulosus Solute carrier organic anion transporter family 0.0053 0.019 0.019
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0077 0.0335 0.0335
Loa Loa (eye worm) doublecortin family protein 0.004 0.0115 0.0227
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0106 0.0106
Echinococcus granulosus cpg binding protein 0.0125 0.0625 0.0625
Brugia malayi sodium-independent organic anion transporter family protein 0.0053 0.019 0.0349
Echinococcus multilocularis geminin 0.0371 0.2109 0.2109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0178
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0178
Schistosoma mansoni thyroid hormone receptor 0.0937 0.5528 0.5528
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0063 0.0063
Toxoplasma gondii transporter, major facilitator family protein 0.0053 0.019 0.0881
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0112 0.055 0.055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0145 0.0748 0.1369
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0618 0.4618
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0116 0.0116
Schistosoma mansoni loxhd1 0.004 0.0115 0.0115
Toxoplasma gondii proliferating cell nuclear antigen PCNA1 0.0204 0.1101 0.8846
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0618 0.2931
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0212 0.0387
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Leishmania major mitochondrial DNA polymerase beta 0.0329 0.1858 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0145 0.0748 0.1481
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0329 0.1858 1
Schistosoma mansoni nuclear hormone receptor 0.0145 0.0748 0.0748
Brugia malayi intermediate filament protein 0.0085 0.0387 0.0708
Echinococcus multilocularis proliferating cell nuclear antigen 0.0204 0.1101 0.1101
Onchocerca volvulus 0.0068 0.0286 0.1037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0068 0.0286 0.0523
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0292 0.1076
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Brugia malayi hypothetical protein 0.0068 0.0286 0.0523
Echinococcus granulosus geminin 0.0371 0.2109 0.2109
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0145 0.0748 0.1481
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0171 0.0903 0.0903
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0145 0.0748 0.0748
Brugia malayi ecdysone receptor 0.0068 0.0286 0.0523
Echinococcus multilocularis RUN 0.004 0.0115 0.0115
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0116 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0145 0.0748 0.1369
Entamoeba histolytica hypothetical protein 0.0077 0.034 0.1574
Schistosoma mansoni lamin 0.0085 0.0387 0.0387
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0115 0.0115
Brugia malayi PAS domain containing protein 0.0053 0.0193 0.0353
Loa Loa (eye worm) apoptosis regulator protein 0.009 0.0417 0.0826
Loa Loa (eye worm) hypothetical protein 0.0418 0.2395 0.4741
Schistosoma mansoni nuclear receptor nhr-48 0.0068 0.0286 0.0286
Trypanosoma cruzi MFS transporter, putative 0.0053 0.019 0.0496
Brugia malayi hypothetical protein 0.0068 0.0286 0.0523
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0089 0.0411 0.0411
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0145 0.0748 0.1481
Schistosoma mansoni hypothetical protein 0.009 0.0417 0.0417
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0145 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0038 0.0105 0.0105
Schistosoma mansoni rab6-interacting 0.004 0.0115 0.0115
Schistosoma mansoni organic anion transporter 0.0083 0.0374 0.0374
Trypanosoma cruzi major cysteine proteinase, putative 0.0055 0.0203 0.0565
Echinococcus multilocularis neuropeptide s receptor 0.053 0.3071 0.3071
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0013 0.0013
Loa Loa (eye worm) beta-lactamase 0.0038 0.0103 0.0205
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0148 0.0271
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0106 0.021
Brugia malayi Doublecortin family protein 0.004 0.0115 0.021
Onchocerca volvulus 0.0053 0.019 0.0691
Mycobacterium ulcerans hypothetical protein 0.0102 0.0491 0.2552
Echinococcus granulosus neuropeptide receptor A26 0.053 0.3071 0.3071
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Onchocerca volvulus 0.0083 0.0374 0.1356
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0116 0.0116
Schistosoma mansoni polycystin 1-related 0.004 0.0115 0.0115
Echinococcus multilocularis follistatin 0.0036 0.009 0.009
Schistosoma mansoni cpg binding protein 0.0125 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0178
Brugia malayi Cytochrome P450 family protein 0.0029 0.0046 0.0084
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0068 0.0286 0.0286
Schistosoma mansoni proliferating cell nuclear antigen 0.0204 0.1101 0.1101
Onchocerca volvulus 0.0038 0.0103 0.0375
Schistosoma mansoni zinc finger protein 0.0068 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.004 0.0115 0.0227
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.0584 0.1156
Trichomonas vaginalis set domain proteins, putative 0.0477 0.2754 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0036 0.009 0.0164
Loa Loa (eye worm) hypothetical protein 0.009 0.0417 0.0826
Brugia malayi proliferating cell nuclear antigen (PCNA) 0.0204 0.1101 0.2015
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0152 0.0277
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0068 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0062 0.025 0.0494
Schistosoma mansoni survival motor neuron protein 0.0053 0.019 0.019
Onchocerca volvulus 0.0036 0.009 0.0326
Echinococcus multilocularis Protein lozenge 0.0052 0.0189 0.0189
Echinococcus multilocularis lamin 0.0085 0.0387 0.0387
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0063 0.0063
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.019 0.0348
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Treponema pallidum fructose-bisphosphate aldolase 0.0276 0.1537 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0377
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0204 0.1101 0.3924
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0212 0.0387
Echinococcus multilocularis neuropeptide receptor A26 0.053 0.3071 0.3071
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0256 0.0869
Leishmania major proliferative cell nuclear antigen (PCNA), putative 0.0204 0.1101 0.5686
Loa Loa (eye worm) hypothetical protein 0.0056 0.0212 0.0419
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0115 0.0114
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0063 0.0063
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0046 0.0091
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0053 0.019 0.019
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0116 0.0116
Schistosoma mansoni lipoxygenase 0.004 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.1678 1 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0171 0.0903 0.4558
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.009 0.0417 0.0417
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0103 0.0103
Schistosoma mansoni follistatin 0.0036 0.009 0.009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0145 0.0748 0.1481
Plasmodium falciparum proliferating cell nuclear antigen 1 0.0204 0.1101 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Echinococcus granulosus agrin 0.0036 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.004 0.0116 0.023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0276 0.1537 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0618 0.3385
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0145 0.0748 0.1481
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Echinococcus granulosus ecdysone induced protein 78C 0.0145 0.0748 0.0748
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0089 0.0411 0.0813
Onchocerca volvulus 0.0145 0.0748 0.2715
Schistosoma mansoni rab6-interacting 0.004 0.0115 0.0115
Leishmania major cathepsin L-like protease 0.0069 0.0292 0.1076
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0171 0.0903 0.0903
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.009 0.0417 0.0417
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0116 0.0072
Brugia malayi hypothetical protein 0.004 0.0115 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0112 0.055 0.055
Giardia lamblia PcnA 0.0204 0.1101 0.6933
Schistosoma mansoni hypothetical protein 0.0058 0.0224 0.0224
Onchocerca volvulus 0.0053 0.019 0.069
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0152 0.0277
Loa Loa (eye worm) hypothetical protein 0.085 0.5002 0.9902
Schistosoma mansoni organic anion transporter 0.0053 0.019 0.019
Brugia malayi glutaminase DH11.1 0.029 0.1623 0.297
Echinococcus granulosus microtubule associated protein 2 0.0752 0.4409 0.4409
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0135 0.0686 0.3833
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0205
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0145 0.0748 0.0748
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0116 0.0072
Brugia malayi photoreceptor-specific nuclear receptor 0.0145 0.0748 0.1369
Brugia malayi sodium-independent organic anion transporter family protein 0.0083 0.0374 0.0684
Echinococcus granulosus proliferating cell nuclear antigen 0.0204 0.1101 0.1101
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0013 0.0013
Echinococcus granulosus neuropeptide s receptor 0.053 0.3071 0.3071
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0792 0.4652 0.4652
Schistosoma mansoni hypothetical protein 0.009 0.0417 0.0417
Brugia malayi Nuclear hormone receptor E75 0.0068 0.0286 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0116 0.0301
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0116 0.0116
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0145 0.0748 0.0748
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.034 0.034
Brugia malayi hypothetical protein 0.0077 0.0335 0.0613
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.025 0.025
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0036 0.009 0.0164
Echinococcus multilocularis lamin dm0 0.0085 0.0387 0.0387
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0286 0.0286
Schistosoma mansoni nuclear hormone receptor 0.0068 0.0286 0.0286
Loa Loa (eye worm) DR-78 0.0068 0.0286 0.0566
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0171 0.0903 0.1653
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0377
Loa Loa (eye worm) hypothetical protein 0.0083 0.0374 0.074
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0145 0.0748 0.0748
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0068 0.0286 0.0286
Onchocerca volvulus Putative organic anion transporter 0.0053 0.019 0.0691
Brugia malayi orphan nuclear receptor NR2E1 0.0068 0.0286 0.0523
Trichomonas vaginalis esterase, putative 0.0038 0.0103 0.0255
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.025 0.025
Brugia malayi tailless protein 0.0068 0.0286 0.0523
Loa Loa (eye worm) glutaminase 2 0.029 0.1623 0.3213
Brugia malayi Intermediate filament tail domain containing protein 0.0085 0.0387 0.0708
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0618 0.0618
Trichomonas vaginalis glutaminase, putative 0.029 0.1623 0.5842
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0103 0.0255
Loa Loa (eye worm) hypothetical protein 0.0038 0.0105 0.0207
Brugia malayi SPARC precursor 0.0036 0.009 0.0164
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.009 0.0417 0.0417
Schistosoma mansoni steroid hormone receptor ad4bp 0.0145 0.0748 0.0748
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0145 0.0748 0.1369
Loa Loa (eye worm) hypothetical protein 0.0084 0.0378 0.0748
Onchocerca volvulus 0.0053 0.019 0.0691
Loa Loa (eye worm) hypothetical protein 0.004 0.0112 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0252 0.1394 0.1394
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0023 0.0013 0.0013
Echinococcus granulosus Nuclear hormone receptor HR96 0.0068 0.0286 0.0286
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0204 0.1101 0.3924
Echinococcus multilocularis agrin 0.0036 0.009 0.009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0171 0.0903 0.5264
Brugia malayi secreted modular calcium-binding protein 1 0.0036 0.009 0.0164
Echinococcus granulosus nuclear receptor nhr 48 0.0068 0.0286 0.0286
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0106 0.0106
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.025 0.025
Mycobacterium tuberculosis Conserved hypothetical protein 0.0173 0.0919 0.6563
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0068 0.0286 0.0286
Brugia malayi steroid hormone receptor 0.0145 0.0748 0.1369
Brugia malayi hypothetical protein 0.0053 0.019 0.0349
Giardia lamblia Kinase, PLK 0.0089 0.0411 0.2074
Onchocerca volvulus 0.0118 0.0584 0.212
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0204 0.1101 0.5686
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0063 0.0063
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0068 0.0286 0.0566
Loa Loa (eye worm) hypothetical protein 0.0418 0.2395 0.4741
Trypanosoma cruzi polo-like protein kinase, putative 0.0089 0.0411 0.1752
Brugia malayi hypothetical protein 0.0077 0.0335 0.0613
Echinococcus multilocularis FTZ F1 alpha 0.0145 0.0748 0.0748
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.011 0.011
Echinococcus granulosus nmda type glutamate receptor 0.0055 0.0203 0.0203
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0105 0.0191
Echinococcus multilocularis microtubule associated protein 2 0.0752 0.4409 0.4409
Onchocerca volvulus Protein ultraspiracle homolog 0.0145 0.0748 0.2715
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0116 0.0072
Echinococcus granulosus FTZ F1 alpha 0.0145 0.0748 0.0748
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0171 0.0903 0.644
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0152 0.0277
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0115 0.0115
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.034 0.034
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0077 0.0335 0.0335
Brugia malayi Nuclear hormone receptor-like 1 0.0858 0.5052 0.9245
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0411 0.1385
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0145 0.0748 0.1369
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0145 0.0748 0.1369
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0159 0.0834 0.1651
Brugia malayi beta-lactamase family protein 0.0038 0.0103 0.0189
Loa Loa (eye worm) nuclear hormone receptor 0.0068 0.0286 0.0566
Brugia malayi beta-lactamase 0.0038 0.0103 0.0189
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0148 0.0294
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0089 0.0411 0.0411
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0145 0.0748 0.1369
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0171 0.0903 0.5264
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.009 0.0417 0.0764
Onchocerca volvulus Putative organic anion transporter 0.0053 0.019 0.0691
Trypanosoma brucei proliferative cell nuclear antigen (PCNA), putative 0.0204 0.1101 0.5686
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0068 0.0286 0.1037
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.1233 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0205
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0145 0.0748 0.1481
Schistosoma mansoni lozenge 0.0052 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0178
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0077 0.0335 0.0664
Entamoeba histolytica hypothetical protein 0.0077 0.034 0.1574
Mycobacterium ulcerans hypothetical protein 0.0173 0.0919 0.5365
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.0813 0.4041
Loa Loa (eye worm) hypothetical protein 0.0077 0.0335 0.0664
Onchocerca volvulus 0.0053 0.019 0.0691
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0276 0.1537 0.5527
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0204 0.1101 1
Brugia malayi hypothetical protein 0.004 0.0115 0.021
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0139 0.0387
Onchocerca volvulus Serine\/threonine kinase homolog 0.0089 0.0411 0.1491
Echinococcus granulosus intermediate filament protein 0.0085 0.0387 0.0387
Brugia malayi nuclear receptor NHR-88 0.0068 0.0286 0.0523
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0171 0.0903 0.0903
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0618 0.4141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0292 0.1076
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0053 0.019 0.019
Brugia malayi prostaglandin transporter 0.0053 0.019 0.0349
Loa Loa (eye worm) hypoxia-induced factor 1 0.0164 0.0863 0.1708
Onchocerca volvulus 0.0038 0.0103 0.0375
Echinococcus multilocularis cpg binding protein 0.0125 0.0625 0.0625
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0205
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Echinococcus multilocularis thyroid hormone receptor alpha 0.0937 0.5528 0.5528
Schistosoma mansoni cpg binding protein 0.0125 0.0625 0.0625
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0089 0.0411 0.1752
Trichomonas vaginalis CAMK family protein kinase 0.0044 0.0139 0.0387
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0145 0.0748 0.1481
Loa Loa (eye worm) hypothetical protein 0.0178 0.0946 0.1872
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0077 0.0335 0.0335
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0244 0.1346 1
Brugia malayi hypothetical protein 0.0178 0.0946 0.1731
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0156 0.0813 0.4041
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0115 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0145 0.0748 0.1369
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0115 0.0115
Brugia malayi Pre-SET motif family protein 0.042 0.2406 0.4403
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0103 0.0103
Brugia malayi Steroid receptor seven-up type 2 0.0145 0.0748 0.1369
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0103 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0145 0.0748 0.1369
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0204 0.1101 0.5686
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0792 0.4652 0.4652
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0116 0.0072
Schistosoma mansoni microtubule-associated protein tau 0.0752 0.4409 0.4409
Schistosoma mansoni lipoxygenase 0.0112 0.055 0.055
Brugia malayi Nuclear hormone receptor-like 1 0.0926 0.5464 1
Entamoeba histolytica proliferating cell nuclear antigen, putative 0.0204 0.1101 0.6933
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0109 0.053 0.4274
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0276 0.1537 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0286 0.0566
Brugia malayi CXXC zinc finger family protein 0.0118 0.0584 0.1069
Leishmania major cathepsin L-like protease 0.0069 0.0292 0.1076
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0145 0.0748 0.0748
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0292 0.1076
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0373 0.0373
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0068 0.0286 0.1037
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0085 0.0387 0.0766
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0145 0.0748 0.0748
Echinococcus multilocularis dnaJ subfamily B 0.1678 1 1
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.009 0.0417 0.0417
Loa Loa (eye worm) runx1 0.0052 0.0189 0.0375
Schistosoma mansoni nuclear receptor 0.0068 0.0286 0.0286
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0373 0.0373
Schistosoma mansoni coup transcription factor 0.0145 0.0748 0.0748
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0145 0.0748 0.2715
Schistosoma mansoni hypothetical protein 0.0371 0.2109 0.2109
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0115 0.0115
Mycobacterium ulcerans putative regulatory protein 0.0039 0.011 0.0041
Echinococcus multilocularis nuclear receptor nhr 48 0.0068 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0085 0.0387 0.0766
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0068 0.0286 0.0286
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0145 0.0748 0.0748
Onchocerca volvulus 0.004 0.0115 0.0417
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0145 0.0748 0.0748
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0212 0.0419
Schistosoma mansoni single-minded 0.0053 0.0193 0.0193
Schistosoma mansoni proliferating cell nuclear antigen 0.0204 0.1101 0.1101
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0411 0.0411
Brugia malayi hypothetical protein 0.0077 0.034 0.0622
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0618 0.0618
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0103 0.0255
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0077 0.0335 0.0664
Onchocerca volvulus 0.0418 0.2395 0.8695
Loa Loa (eye worm) hypothetical protein 0.0053 0.019 0.0377
Schistosoma mansoni glutamate receptor NMDA 0.0023 0.0013 0.0013
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0145 0.0748 0.0748
Onchocerca volvulus 0.0039 0.011 0.0398
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0329 0.1858 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0618 0.3385

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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