Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.4066 | 0.4066 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.1842 | 0.1842 |
Echinococcus multilocularis | lamin | 0.0027 | 0.1842 | 0.1756 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4605 | 0.5763 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4605 | 0.5763 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7527 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.1842 | 0.1756 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4605 | 0.5488 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0348 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.1842 | 0.1927 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.1039 | 0.0891 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.073 | 0.0785 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4605 | 0.5763 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.1039 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.4769 | 0.5124 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.121 | 0.13 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.177 | 0.1901 |
Trypanosoma brucei | ISWI complex protein | 0.0017 | 0.0348 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.1842 | 0.1979 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.4605 | 0.4947 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0348 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.1519 | 0.151 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7527 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4605 | 0.5488 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4605 | 0.5488 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4605 | 0.5763 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.1039 | 0.0592 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0348 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0069 | 0.8105 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.121 | 0.1112 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0631 | 0.0366 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.1842 | 0.1756 |
Schistosoma mansoni | lamin | 0.0027 | 0.1842 | 0.1927 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.4605 | 0.4605 |
Echinococcus granulosus | lamin | 0.0027 | 0.1842 | 0.1756 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.1902 | 0.1902 |
Onchocerca volvulus | 0.0027 | 0.1842 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0631 | 0.0678 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3684 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1842 | 0.1979 |
Schistosoma mansoni | lamin | 0.0027 | 0.1842 | 0.1927 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0631 | 0.0366 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3684 | 0.4427 |
Onchocerca volvulus | 0.0027 | 0.1842 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4078 | 0.4381 |
Echinococcus multilocularis | musashi | 0.0027 | 0.1842 | 0.1756 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0631 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.9308 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4461 | 0.4792 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.1842 | 0.1842 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.1842 | 0.1979 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.1519 | 0.1287 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.1519 | 0.1287 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.1842 | 0.1756 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0631 | 0.0366 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.