Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.0537 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | G-protein coupled receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | Serotonin receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0049 | 0.0013 | 0.5 |
Brugia malayi | Melatonin receptor type 1A | 0.0049 | 0.0013 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | follicle stimulating hormone receptor | 0.0049 | 0.0013 | 1 |
Echinococcus granulosus | geminin | 0.0176 | 0.0537 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0049 | 0.0013 | 1 |
Brugia malayi | Dopamine receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | larval opioid receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | Serotonin receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0049 | 0.0013 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | RE15519p | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Echinococcus multilocularis | geminin | 0.0176 | 0.0537 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Mycobacterium ulcerans | pantoate--beta-alanine ligase | 0.248 | 1 | 0.5 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Brugia malayi | neuropeptide F receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0049 | 0.0013 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0049 | 0.0013 | 1 |
Toxoplasma gondii | pantoate-beta-alanine ligase | 0.248 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Mycobacterium tuberculosis | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.248 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.0537 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | AKH receptor | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0049 | 0.0013 | 0.5 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0013 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0049 | 0.0013 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0049 | 0.0013 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0049 | 0.0013 | 1 |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 | |
Onchocerca volvulus | 0.0049 | 0.0013 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.