Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0114 | 0.0161 | 0.0161 |
Brugia malayi | Protein kinase domain containing protein | 0.0114 | 0.0161 | 0.0138 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0114 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0114 | 0.0161 | 0.0161 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0114 | 0.0161 | 0.0161 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0212 | 0.1102 | 0.1102 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0114 | 0.0161 | 0.0161 |
Brugia malayi | Protein kinase domain containing protein | 0.0114 | 0.0161 | 0.0138 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0925 | 0.798 | 0.798 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1135 | 1 | 1 |
Onchocerca volvulus | 0.0098 | 0 | 0.5 | |
Echinococcus multilocularis | protein kinase c iota type | 0.0195 | 0.094 | 0.094 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0114 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.1135 | 1 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0114 | 0.0161 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0212 | 0.1102 | 0.1102 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0925 | 0.798 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0161 | 0.0161 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0212 | 0.1102 | 0.1102 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0114 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0131 | 0.0323 | 0.0323 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0114 | 0.0161 | 0.0161 |
Toxoplasma gondii | AGC kinase | 0.0114 | 0.0161 | 0.5 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0114 | 0.0161 | 0.0161 |
Brugia malayi | Hr1 repeat family protein | 0.0114 | 0.0161 | 0.0138 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0195 | 0.094 | 0.094 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0114 | 0.0161 | 0.0161 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.1037 | 0.9059 | 0.9059 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0114 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0114 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0114 | 0.0161 | 0.0161 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0114 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0114 | 0.0161 | 0.0161 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0114 | 0.0161 | 0.0161 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0114 | 0.0161 | 0.0138 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0114 | 0.0161 | 0.0161 |
Brugia malayi | Protein kinase domain containing protein | 0.0114 | 0.0161 | 0.0138 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0131 | 0.0323 | 0.0323 |
Echinococcus granulosus | protein kinase c iota type | 0.0195 | 0.094 | 0.094 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0114 | 0.0161 | 0.0161 |
Echinococcus granulosus | protein kinase c epsilon type | 0.1135 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0114 | 0.0161 | 0.0161 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.1135 | 1 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0212 | 0.1102 | 0.1102 |
Schistosoma mansoni | serine/threonine kinase | 0.0114 | 0.0161 | 0.0161 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0114 | 0.0161 | 0.0161 |
Trichomonas vaginalis | AGC family protein kinase | 0.0114 | 0.0161 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0114 | 0.0161 | 0.0161 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.