Detailed information for compound 807274

Basic information

Technical information
  • TDR Targets ID: 807274
  • Name: 3-hydroxy-3-(2-oxocycloheptyl)-1H-indol-2-one
  • MW: 259.3 | Formula: C15H17NO3
  • H donors: 2 H acceptors: 3 LogP: 1.33 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CCCCCC1C1(O)C(=O)Nc2c1cccc2
  • InChi: 1S/C15H17NO3/c17-13-9-3-1-2-7-11(13)15(19)10-6-4-5-8-12(10)16-14(15)18/h4-6,8,11,19H,1-3,7,9H2,(H,16,18)
  • InChiKey: WRDAYOGORAQJTA-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 3-hydroxy-3-(2-oxocycloheptyl)indolin-2-one
  • 3-hydroxy-3-(2-oxocycloheptyl)-2-indolinone
  • 3-hydroxy-3-(2-ketocycloheptyl)oxindole
  • Oprea1_462886
  • BIM-0007236.P001
  • CBMicro_007237
  • MLS000109714
  • SMR000105653
  • 3-Hydroxy-3-(2-oxo-cycloheptyl)-1,3-dihydro-indol-2-one
  • BAS 00479765
  • ST073074
  • Oprea1_445046

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references
Bacillus subtilis (strain 168) ATP-dependent Clp protease proteolytic subunit Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K06275 parvin, putative Get druggable targets OG5_127187 All targets in OG5_127187
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium yoelii ATP-dependent Clp protease, proteolytic subunit ClpP, putative Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Probable ClpP-like protease Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127187 All targets in OG5_127187
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) Get druggable targets OG5_127187 All targets in OG5_127187
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein Get druggable targets OG5_127187 All targets in OG5_127187
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Babesia bovis ATP-dependent Clp protease proteolytic subunit 1, putative Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni peptidase Clp (S14 family) Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01358 ATP-dependent Clp protease, protease subunit [EC3.4.21.92], putative Get druggable targets OG5_127187 All targets in OG5_127187
Theileria parva ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus peptidase Clp S14 family Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) Get druggable targets OG5_127187 All targets in OG5_127187
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Treponema pallidum ATP-dependent Clp protease proteolytic subunit Get druggable targets OG5_127187 All targets in OG5_127187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative Get druggable targets OG5_127187 All targets in OG5_127187
Neospora caninum ATP-dependent Clp protease proteolytic subunit, related Get druggable targets OG5_127187 All targets in OG5_127187
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Treponema pallidum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 186 aa 40.3 %
Schistosoma mansoni neuropeptide receptor ATP-dependent Clp protease proteolytic subunit   197 aa 174 aa 20.1 %
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.1 %
Chlamydia trachomatis hypothetical protein ATP-dependent Clp protease proteolytic subunit   197 aa 171 aa 22.8 %
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 35.5 %
Onchocerca volvulus Putative V-type proton ATPase subunit F ATP-dependent Clp protease proteolytic subunit   197 aa 194 aa 54.1 %
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 ATP-dependent Clp protease proteolytic subunit   197 aa 172 aa 57.0 %
Plasmodium berghei ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 180 aa 36.7 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Plasmodium yoelii Clp protease ATP-dependent Clp protease proteolytic subunit   197 aa 183 aa 36.6 %
Plasmodium knowlesi ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 189 aa 36.0 %
Babesia bovis ATP-dependent Clp protease proteolytic subunit, putative ATP-dependent Clp protease proteolytic subunit   197 aa 188 aa 41.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0119 0.103 0.7567
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0031 0.0157 0.0189
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0234 0.0303
Onchocerca volvulus 0.0052 0.0362 0.0809
Trypanosoma brucei multidrug resistance protein E 0.0037 0.0213 0.073
Echinococcus granulosus cyclic nucleotide gated cation channel 0.006 0.0441 0.0441
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0031 0.0157 0.0189
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0286 0.0286
Plasmodium falciparum ABC transporter B family member 4, putative 0.0025 0.0094 0.0148
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0632 0.082
Entamoeba histolytica P-glycoprotein 6, putative 0.0025 0.0094 0.026
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0362 0.0362
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0064 0.0064
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0094 0.0094
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0245 0.0317
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0058 0.0069
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.005 0.005
Brugia malayi ABC transporter family protein 0.0071 0.0553 0.0717
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0025 0.0094 0.0103
Plasmodium falciparum glutathione reductase 0.0053 0.0373 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0086 0.0357
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0373 0.2718
Brugia malayi Papain family cysteine protease containing protein 0.002 0.005 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0194 0.0666
Brugia malayi MAP kinase sur-1 0.0109 0.093 0.1206
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0245 0.0317
Brugia malayi N-terminal motif family protein 0.0016 0.0004 0.0006
Brugia malayi P-glycoprotein-like protein 0.0025 0.0094 0.0122
Loa Loa (eye worm) hypothetical protein 0.0028 0.0125 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0245 0.0317
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0143 0.0143
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Schistosoma mansoni DNA helicase recq5 0.0021 0.0062 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0327 0.0388
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0014 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Brugia malayi Thioredoxin reductase 0.0152 0.136 0.1764
Echinococcus multilocularis hyperpolarization activated cyclic 0.006 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0185 0.1686 0.2187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0011 0.003
Brugia malayi Cathepsin L-like precursor 0.002 0.005 0.0064
Schistosoma mansoni amine GPCR 0.0052 0.0362 0.043
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0246 0.0847
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0067 0.051 0.2682
Brugia malayi sulfakinin receptor protein 0.0052 0.0362 0.0469
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0016 0.0004 0.0005
Brugia malayi Cytochrome P450 family protein 0.0079 0.0632 0.082
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0362 0.0362
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.093 0.4066
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0125 0.0125
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0231 0.0794
Echinococcus granulosus intermediate filament protein 0.0058 0.0421 0.0421
Echinococcus granulosus lysine specific histone demethylase 1A 0.0063 0.0473 0.0473
Schistosoma mansoni amine GPCR 0.0052 0.0362 0.043
Echinococcus granulosus hyperpolarization activated cyclic 0.006 0.0441 0.0441
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0394 0.0642
Schistosoma mansoni thyroid hormone receptor 0.004 0.0245 0.029
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0064 0.0064
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0031 0.0157 0.0175
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0094 0.0785 0.1018
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0044 0.0286 0.0371
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0031 0.0157 0.0189
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0561 0.0727
Onchocerca volvulus 0.004 0.0245 0.0543
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0208 0.1082
Trichomonas vaginalis abcb9, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.005 0.0199
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0362 0.0362
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0058 0.0058
Echinococcus multilocularis expressed conserved protein 0.0181 0.1643 0.1643
Brugia malayi Pre-SET motif family protein 0.0216 0.1988 0.2578
Leishmania major cytochrome p450-like protein 0.0031 0.0157 0.1125
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0286 0.034
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0286 0.034
Onchocerca volvulus 0.0052 0.0362 0.0809
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0246 0.2614
Loa Loa (eye worm) hypothetical protein 0.0135 0.1184 0.1536
Schistosoma mansoni hypothetical protein 0.0052 0.0362 0.043
Echinococcus multilocularis RUN 0.0022 0.0064 0.0064
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0234 0.0303
Loa Loa (eye worm) hypothetical protein 0.0648 0.6271 0.8132
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0172 0.2143
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0058 0.0069
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0066 0.0076
Echinococcus granulosus short transient receptor potential channel 6 0.0044 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0101 0.0853 0.1106
Plasmodium falciparum chloroquine resistance transporter 0.0143 0.1266 0.2078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0332 0.1438
Entamoeba histolytica multidrug resistance protein, putative 0.0037 0.0213 0.0954
Entamoeba histolytica P-glycoprotein-2, putative 0.0071 0.0553 0.2945
Brugia malayi hypothetical protein 0.0044 0.0286 0.0371
Brugia malayi ABC transporter transmembrane region family protein 0.0024 0.0086 0.0111
Trypanosoma brucei protein kinase, putative 0.0109 0.093 0.3242
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1078 0.1281
Echinococcus granulosus mitogen activated protein kinase 0.0109 0.093 0.093
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0036 0.0046
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0245 0.0245
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0037 0.0213 0.1537
Onchocerca volvulus 0.002 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0066 0.0167
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0286 0.0286
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0252
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0071 0.0553 0.2409
Onchocerca volvulus 0.0293 0.2748 0.6202
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0628 0.6075 0.7513
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.139 0.1802
Loa Loa (eye worm) AGC/PKG protein kinase 0.0017 0.0014 0.0018
Schistosoma mansoni multidrug resistance protein 0.0071 0.0553 0.0657
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0031 0.0157 0.0175
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0245 0.0317
Loa Loa (eye worm) hypothetical protein 0.0462 0.4429 0.5743
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0362 0.0362
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0373 0.0483
Toxoplasma gondii transporter, cation channel family protein 0.0044 0.0286 0.1494
Onchocerca volvulus 0.0035 0.0194 0.043
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0245 0.0245
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0362 0.0362
Onchocerca volvulus 0.0044 0.0286 0.0636
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0004 0.0004
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0044 0.0286 0.0636
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0191 0.0508
Brugia malayi PXA domain containing protein 0.0021 0.0058 0.0075
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0037 0.0213 0.073
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0245 0.029
Treponema pallidum sodium- and chloride- dependent transporter 0.0066 0.0507 0.6437
Toxoplasma gondii hypothetical protein 0.0053 0.0374 0.1961
Schistosoma mansoni hypothetical protein 0.0022 0.0064 0.0076
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0894 0.8709 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0109 0.0462
Loa Loa (eye worm) inositol-1 0.0039 0.0231 0.03
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.0094 0.0476
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0135 0.0573
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0039 0.0152
Brugia malayi Egg laying defective protein 4 0.0017 0.0014 0.0018
Toxoplasma gondii transmembrane protein 0.0143 0.1266 0.6692
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0628 0.6075 0.6974
Leishmania major cytochrome p450-like protein 0.0079 0.0632 0.4633
Echinococcus multilocularis peptidase Clp (S14 family) 0.0062 0.0462 0.0462
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0194 0.0835
Echinococcus granulosus voltage gated potassium channel 0.0048 0.0327 0.0327
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0373 0.129
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0362 0.0362
Entamoeba histolytica ATP-binding cassette protein, putative 0.0037 0.0213 0.0954
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0037 0.0213 0.1106
Loa Loa (eye worm) hypothetical protein 0.0063 0.0473 0.0614
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0286 0.0286
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0373 0.0456
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0135 0.1184 0.1536
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0946 0.4135
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0441 0.1917
Echinococcus granulosus RUN 0.0022 0.0064 0.0064
Schistosoma mansoni multidrug resistance protein 0.0024 0.0086 0.0102
Onchocerca volvulus 0.0019 0.0036 0.0071
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0362 0.0362
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Loa Loa (eye worm) solute carrier family 6 member 4 0.0066 0.0507 0.0657
Loa Loa (eye worm) hypothetical protein 0.0027 0.0115 0.0149
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0025 0.0094 0.0103
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0245 0.0245
Schistosoma mansoni hypothetical protein 0.0052 0.0362 0.043
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0109 0.093 0.3242
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0362 0.0362
Giardia lamblia GTOR 0.0049 0.0332 0.3537
Schistosoma mansoni sodium/chloride dependent transporter 0.0066 0.0507 0.0602
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.0658 0.3558
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.005 0.005
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0286 0.034
Schistosoma mansoni multidrug resistance protein 0.0037 0.0213 0.0253
Echinococcus granulosus cathepsin l1 0.002 0.005 0.005
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0373 0.1618
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0058 0.0069
Brugia malayi nuclear hormone receptor 0.0019 0.0036 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0135 0.0573
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0063 0.0473 0.0772
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0286 0.034
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0044 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Mycobacterium ulcerans lipase LipD 0.0035 0.0194 0.0218
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0044 0.0286 0.0986
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.2718
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0387 0.368 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0362 0.0469
Echinococcus granulosus voltage gated hydrogen channel 1 0.0044 0.0286 0.0286
Schistosoma mansoni 60S ribosomal protein L21 0.0055 0.0394 0.0468
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0194 0.0194
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0025 0.0094 0.0394
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0063 0.0473 0.1276
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.0094 0.0476
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0286 0.034
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0016 0.0004 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.011 0.0463
Echinococcus multilocularis ATP binding cassette sub family B 0.0025 0.0094 0.0094
Echinococcus multilocularis expressed conserved protein 0.0017 0.0014 0.0014
Loa Loa (eye worm) voltage-gated potassium channel 0.0044 0.0286 0.0371
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0058 0.0058
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0612 0.2129
Echinococcus granulosus tar DNA binding protein 0.0124 0.1078 0.1078
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0373 0.0466
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0246 0.0293
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0077 0.0256
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0052 0.0362 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0058 0.0235
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0044 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0031 0.0157 0.0189
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0246 0.1785
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0016 0.0004 0.0005
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0017 0.0013 0.0011
Schistosoma mansoni amine GPCR 0.0052 0.0362 0.043
Onchocerca volvulus 0.0052 0.0362 0.0809
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0048 0.0327 0.0327
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0231 0.1204
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0245 0.029
Echinococcus granulosus two pore calcium channel protein 2 0.0044 0.0286 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0058 0.0235
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0245 0.0245
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0037 0.0213 0.073
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0451 0.0585
Toxoplasma gondii thioredoxin reductase 0.0152 0.136 0.7194
Echinococcus granulosus g protein coupled receptor 0.0052 0.0362 0.0362
Leishmania major p-glycoprotein 0.0071 0.0553 0.4047
Echinococcus granulosus multidrug resistance protein 1 0.0047 0.0317 0.0317
Mycobacterium ulcerans endonuclease IV 0.0083 0.0672 0.0767
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0031 0.0157 0.0175
Brugia malayi nuclear receptor NHR-67 0.0019 0.0036 0.0046
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0044 0.0286 0.0986
Onchocerca volvulus 0.002 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0111
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0194 0.0252
Loa Loa (eye worm) hypothetical protein 0.0063 0.0473 0.0614
Plasmodium falciparum multidrug resistance protein 2 0.0025 0.0094 0.0148
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0362 0.043
Chlamydia trachomatis endonuclease IV 0.0083 0.0672 0.11
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.0094 0.0476
Schistosoma mansoni hypothetical protein 0.0031 0.0157 0.0186
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0362 0.0362
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0362 0.0362
Echinococcus multilocularis 0.0031 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0083 0.0672 0.0872
Plasmodium falciparum ABC transporter B family member 6, putative 0.0025 0.0094 0.0148
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0362 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0248 0.1071
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.001 0.001
Leishmania major cytochrome p450-like protein 0.0031 0.0157 0.1125
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0167 0.0865
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0031 0.0157 0.0175
Leishmania major cathepsin L-like protease 0.0077 0.0612 0.4486
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0246 0.0246
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0194 0.0218
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0094 0.0094
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0062 0.008
Trichomonas vaginalis ABC transporter, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.011 0.0463
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0332 0.1651
Plasmodium falciparum ABC transporter B family member 7, putative 0.0025 0.0094 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0332 0.1438
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0068 0.008
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0362 0.0809
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0058 0.0058
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0362 0.0469
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0071 0.0553 0.0717
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0058 0.0058
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0062 0.0462 0.0567
Echinococcus multilocularis mitogen activated protein kinase 0.0109 0.093 0.093
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0648 0.6271 0.6271
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0047 0.0047
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0058 0.0058
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0047 0.0317 0.1372
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0194 0.0835
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0373 0.0423
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 0.0897
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0044 0.0286 0.034
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0362 0.0362
Echinococcus multilocularis potassium voltage gated channel protein 0.0135 0.1184 0.1184
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0362 0.043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0245 0.029
Brugia malayi Heterochromatin protein 1 0.0072 0.0561 0.0727
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0373 0.0607
Onchocerca volvulus 0.002 0.005 0.0102
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Brugia malayi Dopamine receptor 0.0052 0.0362 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0387 0.368 0.4549
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0071 0.0553 0.0553
Brugia malayi ABC transporter transmembrane region family protein 0.0037 0.0213 0.0276
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0033 0.0172 0.0276
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0036 0.0036
Echinococcus multilocularis protein dispatched 1 0.0094 0.0785 0.0785
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0025 0.0094 0.0148
Loa Loa (eye worm) hypothetical protein 0.0048 0.0327 0.0424
Schistosoma mansoni cpg binding protein 0.0064 0.0485 0.0576
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.004 0.0246 0.0319
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0549 0.0652
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0628 0.6075 0.6974
Schistosoma mansoni survival motor neuron protein 0.0052 0.0367 0.0436
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0064 0.0098
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0894 0.8709 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0332 0.1146
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0233 0.0802
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0025 0.0094 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0055 0.0394 0.0468
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0031 0.0157 0.0534
Schistosoma mansoni neuropeptide receptor 0.0052 0.0362 0.043
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0125 0.0125
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0362 0.0469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Echinococcus granulosus lamin 0.0058 0.0421 0.0421
Entamoeba histolytica P-glycoprotein 5, putative 0.0071 0.0553 0.2945
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0062 0.0624
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0025 0.0094 0.0314
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0194 0.0235
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0129 0.1132 0.1132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0374 0.1623
Echinococcus multilocularis dnaJ subfamily B 0.0865 0.8418 0.8418
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0102 0.0429
Toxoplasma gondii cathepsin CPL 0.002 0.005 0.024
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) ion channel NompC 0.0044 0.0286 0.0371
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0031 0.0157 0.0189
Mycobacterium ulcerans oxidoreductase 0.0063 0.0473 0.0539
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.0549 0.0549
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0245 0.0245
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.093 0.3242
Onchocerca volvulus 0.0022 0.0064 0.0134
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0044 0.0286 0.0371
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0033 0.0172 0.0276
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0194 0.0313
Schistosoma mansoni transient receptor potential channel 0.0044 0.0286 0.034
Schistosoma mansoni hypothetical protein 0.0522 0.5024 0.5968
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0672 0.11
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0332 0.1651
Echinococcus multilocularis translocator protein 0.0293 0.2748 0.2748
Echinococcus granulosus potassium voltage gated channel protein 0.0048 0.0327 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0245 0.0317
Schistosoma mansoni hypothetical protein 0.0522 0.5024 0.5968
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0025 0.0094 0.0314
Echinococcus multilocularis voltage gated potassium channel 0.0048 0.0327 0.0327
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0612 0.2129
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0245 0.0317
Brugia malayi steroid hormone receptor 0.004 0.0245 0.0317
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0286 0.0286
Plasmodium vivax vivapain-2 0.002 0.005 0.0075
Echinococcus multilocularis potassium large conductance calcium activated 0.0044 0.0286 0.0286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.129
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0245 0.0245
Schistosoma mansoni nuclear receptor 0.0019 0.0036 0.0042
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0245 0.0245
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0016 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0193 0.1759 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.0094 0.0476
Loa Loa (eye worm) thioredoxin reductase 0.0152 0.136 0.1764
Echinococcus granulosus short transient receptor potential channel 6 0.0044 0.0286 0.0286
Schistosoma mansoni rab6-interacting 0.0022 0.0064 0.0076
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0044 0.0286 0.0371
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0245 0.0245
Brugia malayi cation channel family protein 0.0044 0.0286 0.0371
Schistosoma mansoni nuclear hormone receptor 0.004 0.0245 0.029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0063 0.0473 0.058
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0031 0.0157 0.0175
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Schistosoma mansoni inositol monophosphatase 0.0039 0.0231 0.0275
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0062 0.0095
Brugia malayi ecdysteroid receptor 0.004 0.0245 0.0317
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0048 0.0327 0.0424
Loa Loa (eye worm) ryanodine receptor 0.0044 0.0286 0.0371
Brugia malayi Probable ClpP-like protease 0.0094 0.0785 0.1018
Toxoplasma gondii LsmAD domain-containing protein 0.0055 0.0394 0.2068
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.093 0.1105
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0063 0.0473 0.0562
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0071 0.0553 0.0553
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0362 0.0362
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0048 0.0327 0.0327
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.0658 0.3558
Plasmodium vivax ABC transporter B family member 3, putative 0.0025 0.0094 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0233 0.1004
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0031 0.0157 0.0175
Leishmania major protein kinase, putative 0.0017 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0546 0.1897
Schistosoma mansoni lamin 0.0058 0.0421 0.0501
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0337 0.0337
Brugia malayi Melatonin receptor type 1A 0.0052 0.0362 0.0469
Schistosoma mansoni hypothetical protein 0.0044 0.0286 0.034
Echinococcus granulosus shaker cognate 0.0048 0.0327 0.0327
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0348 0.3296 0.4073
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0194 0.0835
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0672 0.0872
Echinococcus granulosus patatin phospholipase domain containing protein 0.0016 0.0004 0.0004
Echinococcus multilocularis multidrug resistance associated protein 1 0.0037 0.0213 0.0213
Plasmodium falciparum multidrug resistance-associated protein 1 0.0025 0.0094 0.0148
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0245 0.0317
Plasmodium vivax thioredoxin reductase, putative 0.0152 0.136 0.2233
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0246 0.1063
Loa Loa (eye worm) hypothetical protein 0.0063 0.0473 0.0614
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0245 0.0317
Loa Loa (eye worm) hypothetical protein 0.0185 0.1686 0.2187
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0025 0.0094 0.0662
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0362 0.043
Echinococcus multilocularis lamin 0.0058 0.0421 0.0421
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0245 0.0245
Schistosoma mansoni multidrug resistance protein 0.0071 0.0553 0.0657
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0058 0.0075
Loa Loa (eye worm) histone methyltransferase 0.002 0.0047 0.006
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0017 0.0014 0.0052
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0058 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0102 0.0429
Onchocerca volvulus 0.0035 0.0194 0.043
Mycobacterium leprae putative cytochrome p450 0.0031 0.0157 0.0415
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni intermediate filament proteins 0.0058 0.0421 0.0501
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0083 0.0669 0.0867
Brugia malayi Cathepsin L-like precursor 0.002 0.005 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0102 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0058 0.0235
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0071 0.0553 0.2409
Loa Loa (eye worm) hypothetical protein 0.0048 0.0325 0.0421
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Onchocerca volvulus 0.0052 0.0362 0.0809
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0194 0.0835
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0071 0.0553 0.2409
Entamoeba histolytica hypothetical protein 0.0021 0.0058 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0058 0.0235
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0039 0.0152
Echinococcus granulosus cGMP dependent protein kinase 1 0.0017 0.0014 0.0014
Leishmania major cysteine peptidase A (CPA) 0.002 0.005 0.0334
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0068 0.0088
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0362 0.043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0094 0.0122
Echinococcus granulosus expressed conserved protein 0.0181 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.007 0.0544 0.0706
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0037 0.0213 0.0276
Schistosoma mansoni cpg binding protein 0.0064 0.0485 0.0576
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0031 0.0157 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0672 0.1817
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0286 0.034
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0111 0.0946 0.4135
Entamoeba histolytica ATP-binding cassette protein, putative 0.0037 0.0213 0.0954
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0362 0.0362
Toxoplasma gondii hypothetical protein 0.0162 0.1452 0.7683
Schistosoma mansoni hypothetical protein 0.008 0.0639 0.0759
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0062 0.0306
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0191 0.0231
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0071 0.0553 0.0679
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0362 0.0362
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0109 0.093 0.4913
Loa Loa (eye worm) hypothetical protein 0.0162 0.1452 0.1883
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Brugia malayi CXXC zinc finger family protein 0.0061 0.0451 0.0585
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0332 0.043
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0421 0.0546
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0648 0.6271 0.6271
Brugia malayi Pre-SET motif family protein 0.0032 0.0167 0.0217
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0031 0.0157 0.0175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Echinococcus multilocularis cysteine protease 0.002 0.005 0.005
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.0658 0.3558
Schistosoma mansoni hypothetical protein 0.0052 0.0362 0.043
Schistosoma mansoni hypothetical protein 0.0049 0.0337 0.04
Echinococcus granulosus bloom syndrome protein 0.0021 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0058 0.0075
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0362 0.0362
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0362 0.0362
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0245 0.029
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0194 0.0517
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0246 0.1063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Echinococcus granulosus neuropeptide receptor 0.0052 0.0362 0.0362
Brugia malayi ecdysone receptor 0.0019 0.0036 0.0046
Brugia malayi tailless protein 0.0019 0.0036 0.0046
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.006 0.0441 0.0441
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0362 0.0469
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0648 0.6271 0.6271
Loa Loa (eye worm) hypothetical protein 0.0055 0.0394 0.0511
Schistosoma mansoni cytochrome P450 0.0031 0.0157 0.0186
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0058 0.0069
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0058 0.0058
Onchocerca volvulus 0.0052 0.0362 0.0809
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0362 0.0362
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0167 0.0199
Trypanosoma cruzi UDP-galactopyranose mutase 0.0063 0.0473 0.1642
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0278 0.062
Treponema pallidum NADH oxidase 0.0053 0.0373 0.4721
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0246 0.0246
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0011 0.005
Echinococcus multilocularis neuropeptide receptor A26 0.1025 1 1
Trichomonas vaginalis ABC transporter, putative 0.0071 0.0553 0.2409
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0044 0.0286 0.0286
Onchocerca volvulus 0.0052 0.0362 0.0809
Trypanosoma brucei PAB1-binding protein , putative 0.0055 0.0394 0.1364
Toxoplasma gondii transporter, cation channel family protein 0.0206 0.1889 1
Brugia malayi hypothetical protein 0.0063 0.0473 0.0614
Schistosoma mansoni biogenic amine receptor 0.0052 0.0362 0.043
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0044 0.0286 0.0371
Leishmania major cathepsin L-like protease 0.002 0.005 0.0334
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0102 0.0429
Brugia malayi G-protein coupled receptor 0.0052 0.0362 0.0469
Onchocerca volvulus Cathepsin L homolog 0.002 0.005 0.0102
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0337 0.0337
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0031 0.0157 0.0534
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0286 0.0286
Echinococcus multilocularis Niemann Pick C1 protein 0.0275 0.2579 0.2579
Echinococcus granulosus Niemann Pick C1 protein 0.0275 0.2579 0.2579
Leishmania major cathepsin L-like protease 0.0077 0.0612 0.4486
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0058 0.0058
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0048 0.0327 0.0327
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Schistosoma mansoni amine oxidase 0.0063 0.0473 0.0562
Schistosoma mansoni neuropeptide receptor 0.0052 0.0362 0.043
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0155 0.1383 0.1383
Toxoplasma gondii hypothetical protein 0.0033 0.0172 0.0888
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0332 0.2415
Giardia lamblia Multidrug resistance-associated protein 1 0.0036 0.0204 0.2159
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0231 0.1673
Loa Loa (eye worm) RecQ helicase 0.0021 0.0062 0.008
Brugia malayi Cyclic-nucleotide gated cation channel 0.006 0.0441 0.0572
Brugia malayi hypothetical protein 0.0035 0.0201 0.0261
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Entamoeba histolytica ATP-binding cassette protein, putative 0.0037 0.0213 0.0954
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0156 0.0202
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0066 0.0507 0.0602
Brugia malayi olfactory channel protein osm-9 0.0044 0.0286 0.0371
Loa Loa (eye worm) hypothetical protein 0.0206 0.1889 0.245
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0058 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0064 0.0064
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0058 0.0075
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.005 0.0075
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0036 0.0204 0.0265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0231 0.0996
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0286 0.0286
Mycobacterium ulcerans monoamine oxidase 0.0063 0.0473 0.0539
Brugia malayi CHE-14 protein 0.0083 0.0669 0.0867
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0362 0.0362
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0473 0.0772
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0373 0.2718
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0071 0.0553 0.2911
Echinococcus granulosus voltage dependent calcium channel 0.0206 0.1889 0.1889
Schistosoma mansoni hypothetical protein 0.0054 0.0384 0.0456
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0016 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0106 0.0902 0.1072
Loa Loa (eye worm) hypothetical protein 0.0256 0.2388 0.3097
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.005 0.0159
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0031 0.0157 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0167 0.0199
Toxoplasma gondii hypothetical protein 0.0044 0.0286 0.1494
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0245 0.0317
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0016 0.0004 0.0004
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0011 0.005
Brugia malayi G-protein coupled receptor 0.0052 0.0362 0.0469
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0036 0.0046
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0036 0.0036
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0233 0.0802
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0245 0.0317
Toxoplasma gondii transporter, cation channel family protein 0.0044 0.0286 0.1494
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0348 0.3296 0.8954
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0058 0.0058
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0036 0.0042
Loa Loa (eye worm) voltage-gated calcium channel 0.0044 0.0286 0.0371
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Brugia malayi Niemann-Pick C1 protein precursor 0.0193 0.1759 0.2281
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0025 0.0094 0.0314
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0024 0.0086 0.0102
Plasmodium vivax ABC transporter B family member 7, putative 0.0025 0.0094 0.0148
Plasmodium falciparum ataxin-2 like protein, putative 0.0055 0.0394 0.0642
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0036 0.0042
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0194 0.0235
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0068 0.0088
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0062 0.0426
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.006 0.0441 0.0524
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0286 0.0286
Echinococcus granulosus lysine specific histone demethylase 1A 0.0063 0.0473 0.0473
Echinococcus multilocularis sodium channel protein 0.0217 0.2002 0.2002
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0094 0.0785 0.0785
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0327 0.0388
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0286 0.0286
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0036 0.0036
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0246 0.0293
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0449 0.1557
Brugia malayi Doublecortin family protein 0.0022 0.0064 0.0083
Echinococcus granulosus dnaJ subfamily B 0.0865 0.8418 0.8418
Entamoeba histolytica hypothetical protein 0.0037 0.0213 0.0954
Brugia malayi hypothetical protein 0.0022 0.0064 0.0083
Onchocerca volvulus 0.0052 0.0362 0.0809
Leishmania major hypothetical protein, conserved 0.0035 0.0194 0.1403
Brugia malayi hypothetical protein 0.0019 0.0036 0.0046
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0062 0.008
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1078 0.1281
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0135 0.1184 0.1184
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0031 0.0157 0.0189
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0129 0.1132 0.1132
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0286 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Trichomonas vaginalis abcb9, putative 0.0071 0.0553 0.2409
Brugia malayi hypothetical protein 0.0256 0.2388 0.3097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Entamoeba histolytica P-glycoprotein 6, putative 0.0025 0.0094 0.026
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0066 0.0085
Loa Loa (eye worm) hypothetical protein 0.0293 0.2748 0.3564
Onchocerca volvulus 0.0035 0.0194 0.043
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0362 0.0362
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0286 0.034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0245 0.0245
Schistosoma mansoni hypothetical protein 0.0049 0.0337 0.04
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0648 0.6271 0.6271
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0044 0.0286 0.0286
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0094 0.0785 0.1286
Echinococcus granulosus geminin 0.0522 0.5024 0.5024
Onchocerca volvulus 0.0052 0.0362 0.0809
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Brugia malayi AKH receptor 0.0052 0.0362 0.0469
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0094 0.0785 0.0785
Echinococcus granulosus transient receptor potential gamma protein 0.0044 0.0286 0.0286
Loa Loa (eye worm) fibroinase 0.002 0.005 0.0064
Echinococcus granulosus potassium voltage gated channel protein 0.0135 0.1184 0.1184
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0037 0.0213 0.1537
Loa Loa (eye worm) hypothetical protein 0.0162 0.1452 0.1883
Echinococcus multilocularis mitogen activated protein kinase 3 0.0109 0.093 0.093
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0031 0.0157 0.0175
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0373 0.129
Mycobacterium tuberculosis Conserved protein 0.0035 0.0194 0.0235
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0348 0.3296 0.4073
Echinococcus multilocularis ATP binding cassette sub family B 0.0025 0.0094 0.0094
Onchocerca volvulus 0.0019 0.0036 0.0071
Schistosoma mansoni transient receptor potential channel 0.0044 0.0286 0.034
Echinococcus multilocularis hyperpolarization activated cyclic 0.006 0.0441 0.0441
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0066 0.0507 0.0657
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.0658 0.3558
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0058 0.0235
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.129
Onchocerca volvulus 0.0246 0.2282 0.5147
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0058 0.0058
Brugia malayi ABC transporter 0.0025 0.0094 0.0122
Brugia malayi hypothetical protein 0.0021 0.0058 0.0075
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0245 0.029
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni lamin 0.0058 0.0421 0.0501
Loa Loa (eye worm) hypothetical protein 0.0071 0.0553 0.0717
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0246 0.0847
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0058 0.0075
Onchocerca volvulus 0.0066 0.0507 0.1136
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0025 0.0094 0.0111
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0167 0.0199
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0628 0.6075 1
Echinococcus multilocularis voltage gated potassium channel 0.0071 0.0549 0.0549
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0252
Echinococcus granulosus multidrug resistance protein 1 0.0071 0.0553 0.0553
Mycobacterium leprae Probable lipase LipE 0.0035 0.0194 0.0517
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0109 0.093 0.3242
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0286 0.1494
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0362 0.043
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0284 0.0337
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0373 0.0607
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0362 0.043
Entamoeba histolytica P-glycoprotein-2 0.0071 0.0553 0.2945
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0231 0.1062
Brugia malayi beta-lactamase 0.0035 0.0194 0.0252
Brugia malayi Cytochrome P450 family protein 0.0031 0.0157 0.0203
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0036 0.0036
Onchocerca volvulus 0.0052 0.0362 0.0809
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0016 0.0004 0.0004
Echinococcus granulosus ryanodine receptor 44f 0.0044 0.0286 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0632 0.082
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0373 0.0607
Loa Loa (eye worm) hypothetical protein 0.0071 0.0553 0.0717
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.005 0.0159
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0245 0.029
Echinococcus multilocularis survival motor neuron protein 1 0.0256 0.2388 0.2388
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0036 0.0046
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0362 0.0362
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0245 0.029
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Echinococcus granulosus microtubule associated protein 2 0.0758 0.7355 0.7355
Brugia malayi nuclear receptor RXR 0.0019 0.0036 0.0046
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0132 0.0559
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0362 0.0469
Schistosoma mansoni ryanodine receptor related 0.0044 0.0286 0.034
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0037 0.0213 0.073
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.0293 0.2748 0.3264
Schistosoma mansoni hypothetical protein 0.008 0.0639 0.0759
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0286 0.034
Echinococcus granulosus potassium large conductance calcium activated 0.0044 0.0286 0.0286
Schistosoma mansoni biogenic amine receptor 0.0052 0.0362 0.043
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0245 0.0317
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0011 0.003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0156 0.0202
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0016 0.0004 0.0004
Brugia malayi nuclear hormone receptor 0.004 0.0245 0.0317
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0794 0.7712 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0373 0.0423
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0362 0.0362
Echinococcus multilocularis transient receptor potential gamma protein 0.0044 0.0286 0.0286
Echinococcus granulosus cyclic nucleotide gated cation channel 0.006 0.0441 0.0441
Schistosoma mansoni multidrug resistance protein 0.0037 0.0213 0.0253
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0031 0.0157 0.1125
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0048 0.0327 0.0327
Schistosoma mansoni voltage-dependent calcium channel 0.0044 0.0286 0.034
Onchocerca volvulus 0.0061 0.0451 0.1009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis serotonin transporter 0.0066 0.0507 0.0507
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.005 0.005
Giardia lamblia MRP-like ABC transporter 0.0037 0.0213 0.2251
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0071 0.0553 0.0553
Brugia malayi nuclear receptor NHR-88 0.0019 0.0036 0.0046
Brugia malayi hypothetical protein 0.0025 0.0094 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0304 0.2861 1
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0037 0.0213 0.0276
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0044 0.0286 0.0636
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0167 0.0167
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0248 0.0551
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Onchocerca volvulus 0.0052 0.0362 0.0809
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0058 0.0069
Mycobacterium leprae Conserved hypothetical protein 0.0031 0.0157 0.0415
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.129
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0031 0.0157 0.0175
Echinococcus multilocularis expressed protein 0.041 0.3909 0.3909
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0362 0.0362
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0058 0.0075
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0245 0.0245
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0278 0.1204
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0068 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0014 0.0017
Loa Loa (eye worm) beta-lactamase 0.0035 0.0194 0.0252
Loa Loa (eye worm) hypothetical protein 0.0155 0.139 0.1802
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0362 0.0362
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0102 0.0429
Schistosoma mansoni voltage-gated potassium channel 0.0166 0.149 0.177
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0062 0.0202
Plasmodium vivax ABC transporter B family member 5, putative 0.0025 0.0094 0.0148
Echinococcus multilocularis multidrug resistance associated protein 7 0.0037 0.0213 0.0213
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0004 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0332 0.043
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0304 0.2861 1
Echinococcus granulosus serotonin transporter 0.0066 0.0507 0.0507
Brugia malayi ABC transporter transmembrane region family protein 0.0025 0.0094 0.0122
Echinococcus multilocularis geminin 0.0522 0.5024 0.5024
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0036 0.0071
Echinococcus granulosus serotonin receptor 0.0052 0.0362 0.0362
Trichomonas vaginalis abcb9, putative 0.0071 0.0553 0.2409
Entamoeba histolytica hypothetical protein 0.0021 0.0058 0.0048
Onchocerca volvulus 0.0032 0.0162 0.0356
Echinococcus multilocularis conserved hypothetical protein 0.0758 0.7355 0.7355
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0327 0.0388
Echinococcus granulosus peptidase Clp S14 family 0.0062 0.0462 0.0462
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0248 0.0322
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.005 0.0199
Brugia malayi amine oxidase, flavin-containing family protein 0.0063 0.0473 0.0614
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0373 0.398
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.006 0.0441 0.0441
Echinococcus granulosus multidrug resistance associated protein 1 0.0037 0.0213 0.0213
Echinococcus multilocularis multidrug resistance protein 1 0.0071 0.0553 0.0553
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0017 0.0014 0.0014
Echinococcus multilocularis musashi 0.0058 0.0421 0.0421
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0044 0.0286 0.034
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0217 0.2002 0.2002
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0785 0.4141
Mycobacterium tuberculosis Conserved protein 0.0035 0.0194 0.0235
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0246 0.1063
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0025 0.0094 0.0103
Mycobacterium ulcerans hypothetical protein 0.0035 0.0194 0.0218
Onchocerca volvulus 0.0052 0.0362 0.0809
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0231 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0109 0.0462
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0648 0.6271 0.7449
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0362 0.0469
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0064 0.0064
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0062 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0138 0.0585
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0231 0.0794
Trypanosoma cruzi UDP-galactopyranose mutase 0.0063 0.0473 0.1642
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis calcium activated potassium channel 0.0045 0.0296 0.0296
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0362 0.0362
Loa Loa (eye worm) voltage-gated potassium channel 0.0048 0.0327 0.0424
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0058 0.0069
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0332 0.0394
Loa Loa (eye worm) hypothetical protein 0.0049 0.0337 0.0437
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0031 0.0157 0.0189
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0362 0.043
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0362 0.0469
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0373 0.0443
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0332 0.0332
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0362 0.0809
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0194 0.0235
Schistosoma mansoni amine oxidase 0.0063 0.0473 0.0562
Schistosoma mansoni multidrug resistance protein 0.0071 0.0553 0.0657
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.129
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0022 0.0066 0.0085
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.006 0.0441 0.0524
Plasmodium vivax ABC transporter B family member 6, putative 0.0025 0.0094 0.0148
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0362 0.0362
Mycobacterium tuberculosis Probable dehydrogenase 0.0348 0.3296 0.4073
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis potassium voltage gated channel protein 0.0048 0.0327 0.0327
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0062 0.0062
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.006 0.0441 0.0572
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0071 0.0553 0.0553
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0373 0.129
Entamoeba histolytica ATP-binding cassette protein, putative 0.0037 0.0213 0.0954
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0062 0.0095
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0441 0.1917
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0048 0.0327 0.0327
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0394 0.1364
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0245 0.0245
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0648 0.6271 0.8132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Brugia malayi hypothetical protein 0.0022 0.0064 0.0083
Onchocerca volvulus 0.0052 0.0367 0.082
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0036 0.0046
Schistosoma mansoni voltage-gated cation channel 0.0648 0.6271 0.7449
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0011 0.0024
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0362 0.0362
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0362 0.043
Echinococcus multilocularis ryanodine receptor 44f 0.0044 0.0286 0.0286
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.0086 0.021
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0036 0.0046
Mycobacterium tuberculosis Possible oxidoreductase 0.0063 0.0473 0.058
Brugia malayi Cathepsin L-like precursor 0.002 0.005 0.0064
Brugia malayi glutathione reductase 0.0152 0.136 0.1764
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0052 0.0362 0.0469
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0362 0.0469
Brugia malayi Inositol-1 0.0039 0.0231 0.03
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0362 0.0469
Onchocerca volvulus 0.0052 0.0362 0.0809
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0561 0.2444
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0058 0.0235
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0031 0.0157 0.0175
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0064 0.0083
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0062 0.0462 0.0567
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Echinococcus multilocularis cysteine protease 0.002 0.005 0.005
Schistosoma mansoni neuropeptide receptor 0.0052 0.0362 0.043
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.0086 0.021
Echinococcus granulosus hypothetical protein 0.0044 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.006 0.0441 0.0572
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0025 0.0094 0.0662
Onchocerca volvulus 0.002 0.005 0.0102
Echinococcus granulosus FTZ F1 alpha 0.004 0.0245 0.0245
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0058 0.0069
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0362 0.0362
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0031 0.0157 0.0534
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0016 0.0004 0.0005
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0362 0.043
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0109 0.093 0.1206
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0066 0.0071
Brugia malayi SWIRM domain containing protein 0.0063 0.0473 0.0614
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0231 0.0261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0063 0.0473 0.0539
Schistosoma mansoni transient receptor potential channel 0.0044 0.0286 0.034
Schistosoma mansoni patched 1 0.0083 0.0669 0.0794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0246 0.0246
Echinococcus multilocularis short transient receptor potential channel 6 0.0044 0.0286 0.0286
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0362 0.0362
Toxoplasma gondii endonuclease IV APN 0.0083 0.0672 0.3544
Leishmania major UDP-galactopyranose mutase 0.0063 0.0473 0.3458
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0245 0.0245
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0011 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0115 0.0149
Entamoeba histolytica P-glycoprotein-5 0.0071 0.0553 0.2945
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0037 0.0213 0.073
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0068 0.008
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0044 0.0286 0.034
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0058 0.0075
Trypanosoma cruzi trypanothione reductase, putative 0.0152 0.136 0.4746
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.007 0.0544 0.0544
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0031 0.0157 0.0189
Brugia malayi TspO/MBR family protein 0.0293 0.2748 0.3564
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0109 0.093 0.3242
Schistosoma mansoni loxhd1 0.0022 0.0064 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0441 0.0524
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.006 0.0441 0.0572
Brugia malayi Cytochrome P450 family protein 0.0073 0.0572 0.0742
Echinococcus multilocularis ATP binding cassette sub family B 0.0025 0.0094 0.0094
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0672 0.0827
Onchocerca volvulus 0.002 0.005 0.0102
Echinococcus multilocularis serotonin receptor 0.0185 0.1686 0.1686
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0194 0.0235
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0648 0.6271 0.6271
Plasmodium falciparum glutathione reductase 0.0152 0.136 0.2233
Brugia malayi hypothetical protein 0.0021 0.0058 0.0075
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0032 0.0162 0.021
Leishmania major trypanothione reductase 0.0152 0.136 1
Echinococcus multilocularis voltage dependent calcium channel 0.0648 0.6271 0.6271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0173 0.074
Echinococcus granulosus sodium leak channel non selective protein 0.0044 0.0286 0.0286
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0362 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0245 0.0317
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Plasmodium vivax SET domain protein, putative 0.0032 0.0167 0.0268
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0572 0.0742
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.006 0.0441 0.0441
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0561 0.2444
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0648 0.6271 0.6271
Plasmodium falciparum protoporphyrinogen oxidase 0.0063 0.0473 0.0772
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0194 0.0235
Entamoeba histolytica ABC transporter, putative 0.0037 0.0213 0.0954
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0362 0.043
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0031 0.0157 0.0175
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0245 0.029
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0058 0.0058
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0068 0.0068
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0362 0.043
Brugia malayi ABC transporter family protein 0.0025 0.0094 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0374 0.1294
Brugia malayi conserved hypotetical protein 0.0019 0.0036 0.0046
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.005 0.0059
Echinococcus granulosus cGMP dependent protein kinase 0.0017 0.0014 0.0014
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0062 0.0062
Schistosoma mansoni hypothetical protein 0.0052 0.0367 0.0436
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0628 0.6075 1
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0194 0.0235
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0047 0.0047
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0025 0.0094 0.0112
Echinococcus multilocularis ATP binding cassette sub family B 0.007 0.0544 0.0544
Brugia malayi beta-lactamase family protein 0.0035 0.0194 0.0252
Leishmania major hypothetical protein, conserved 0.0055 0.0394 0.2875
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0362 0.0362
Brugia malayi Cytochrome P450 family protein 0.0079 0.0632 0.082
Loa Loa (eye worm) hypothetical protein 0.0193 0.1759 0.2281
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0058 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0029 0.0108
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0044 0.0286 0.034
Echinococcus granulosus fmrfamide receptor 0.0052 0.0362 0.0362
Plasmodium falciparum ABC transporter B family member 5, putative 0.0025 0.0094 0.0148
Schistosoma mansoni rab6-interacting 0.0022 0.0064 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0132 0.0559
Echinococcus granulosus sodium channel protein 0.0119 0.103 0.103
Echinococcus granulosus lamin dm0 0.0058 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0033 0.0172 0.0455
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0006
Loa Loa (eye worm) CYP4Cod1 0.0079 0.0632 0.082
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0048 0.0327 0.0424
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0421 0.0546
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1078 0.1281
Schistosoma mansoni amine GPCR 0.0052 0.0362 0.043
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0362 0.0362
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0332 0.1146
Echinococcus granulosus ATP binding cassette sub family B 0.0025 0.0094 0.0094
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0135 0.1184 0.1407
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0031 0.0157 0.0189
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0044 0.0286 0.0371
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.005 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0374 0.1294
Entamoeba histolytica hypothetical protein 0.0021 0.0058 0.0048
Loa Loa (eye worm) TAR-binding protein 0.0124 0.1078 0.1398
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0036 0.0036
Brugia malayi GnHR receptor homolog 0.0052 0.0362 0.0469
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0373 0.1618
Echinococcus granulosus cpg binding protein 0.0064 0.0485 0.0485
Onchocerca volvulus 0.0058 0.0421 0.0943
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0648 0.6271 0.7449
Loa Loa (eye worm) runx1 0.0058 0.0424 0.0549
Trypanosoma cruzi PAB1-binding protein , putative 0.0055 0.0394 0.1364
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0245 0.0317
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0062 0.0202
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0058 0.0058
Trichomonas vaginalis ABC transporter, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0011 0.003
Trypanosoma brucei cytochrome P450, putative 0.0079 0.0632 0.2199
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0058 0.0075
Brugia malayi Cathepsin L-like precursor 0.002 0.005 0.0064
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0362 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0233 0.1004
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0831 0.8085 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0233 0.169
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Leishmania major cathepsin L-like protease 0.002 0.005 0.0334
Loa Loa (eye worm) hypothetical protein 0.0063 0.0473 0.0614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0233 0.1004
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0348 0.3296 0.4073
Loa Loa (eye worm) ABC transporter 0.0025 0.0094 0.0122
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Loa Loa (eye worm) multidrug resistance protein 3 0.0071 0.0553 0.0717
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0025 0.0094 0.0148
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0062 0.0254
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0373 0.1955
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0044 0.0286 0.0371
Leishmania major hypothetical protein, conserved 0.0044 0.0286 0.2077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0011 0.003
Brugia malayi Serotonin receptor 0.0052 0.0362 0.0469
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0071 0.0553 0.0553
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0362 0.0469
Echinococcus granulosus expressed protein 0.041 0.3909 0.3909
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0036 0.0036
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0044 0.0286 0.0371
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0083 0.0669 0.0867
Loa Loa (eye worm) hypothetical protein 0.0066 0.0507 0.0657
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0071 0.0553 0.0553
Entamoeba histolytica P-glycoprotein-2 0.0071 0.0553 0.2945
Mycobacterium ulcerans hypothetical protein 0.0022 0.0066 0.0071
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0025 0.0094 0.0103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0102 0.0429
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0058 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Echinococcus granulosus thioredoxin glutathione reductase 0.0152 0.136 0.136
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0252
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0246 0.1151
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus granulosus Niemann Pick C1 protein 0.0193 0.1759 0.1759
Echinococcus granulosus voltage gated potassium channel 0.0071 0.0549 0.0549
Echinococcus multilocularis transfer RNA-Gly 0.0048 0.0327 0.0327
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0278 0.1204
Loa Loa (eye worm) hypothetical protein 0.0022 0.0064 0.0083
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Schistosoma mansoni polycystin 1-related 0.0022 0.0064 0.0076
Schistosoma mansoni transient receptor potential channel 4 0.0044 0.0286 0.034
Schistosoma mansoni voltage-gated potassium channel 0.0166 0.149 0.177
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0031 0.0157 0.0534
Brugia malayi hypothetical protein 0.0462 0.4429 0.5743
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0231 0.0996
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0327 0.0388
Schistosoma mansoni hypothetical protein 0.0049 0.0337 0.04
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0155 0.1383 0.1793
Schistosoma mansoni opsin-like receptor 0.0052 0.0362 0.043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0362 0.043
Brugia malayi RNA binding protein 0.0124 0.1078 0.1398
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0245 0.0245
Schistosoma mansoni hypothetical protein 0.0025 0.0094 0.0111
Entamoeba histolytica P-glycoprotein-1 0.0071 0.0553 0.2945
Schistosoma mansoni vesicular amine transporter 0.0048 0.0327 0.0388
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0373 0.0423
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.005 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Plasmodium vivax ABC transporter B family member 4, putative 0.0025 0.0094 0.0148
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0421 0.0546
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.1078 0.1398
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0648 0.6271 0.6271
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0231 0.0996
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0327 0.0388
Schistosoma mansoni biogenic amine receptor 0.0052 0.0362 0.043
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0044 0.0286 0.0286
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.093 0.4066
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0167 0.0167
Schistosoma mansoni histamine h1 receptor 0.0052 0.0362 0.043
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.093 0.4066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0014 0.0017
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0058 0.0069
Echinococcus granulosus biogenic amine 5HT receptor 0.0185 0.1686 0.1686
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0245 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0245 0.0317
Mycobacterium tuberculosis Probable oxidoreductase 0.0387 0.368 0.4549
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0071 0.0549 0.0712
Echinococcus multilocularis 0.0025 0.0094 0.0094
Schistosoma mansoni inositol monophosphatase 0.0039 0.0231 0.0275
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0252
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni chromobox protein 0.0072 0.0561 0.0666
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0036 0.0046
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0362 0.0469
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0362 0.0362
Brugia malayi ABC transporter family protein 0.0025 0.0094 0.0122
Loa Loa (eye worm) cytochrome P450 0.0031 0.0157 0.0203
Plasmodium vivax multidrug resistance protein 1, putative 0.0071 0.0553 0.0904
Mycobacterium ulcerans beta-lactamase 0.0035 0.0194 0.0218
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Leishmania major cathepsin L-like protease 0.002 0.005 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.2718
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0031 0.0157 0.0189
Brugia malayi TAR-binding protein 0.0124 0.1078 0.1398
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0902 0.117
Trypanosoma brucei trypanothione reductase 0.0152 0.136 0.4746
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0252
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0231 0.0229
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0286 0.1494
Brugia malayi multidrug resistance related protein 1 0.0037 0.0213 0.0276
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0025 0.0094 0.0314
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0086 0.0357
Loa Loa (eye worm) hypothetical protein 0.0037 0.0213 0.0276
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0044 0.0286 0.0371
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0348 0.3296 0.4073
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0286 0.0286
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.011 0.0463
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0004 0.0004
Onchocerca volvulus 0.0052 0.0362 0.0809
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0373 0.129
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.1137 0.135
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.1988 0.2578
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0036 0.0046
Loa Loa (eye worm) hypothetical protein 0.0139 0.1228 0.1592
Onchocerca volvulus 0.0052 0.0362 0.0809
Brugia malayi ABC transporter family protein 0.0025 0.0094 0.0122
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0062 0.008
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0669 0.2918
Schistosoma mansoni hypothetical protein 0.008 0.0639 0.0759
Giardia lamblia ABC transporter, putative 0.0037 0.0213 0.2251
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0071 0.0553 0.0553
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0245 0.0317
Brugia malayi nuclear receptor NHR-88 0.004 0.0245 0.0317
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0196 0.1789 0.2125
Echinococcus granulosus orexin receptor type 2 0.0052 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0246 0.0246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Brugia malayi voltage-dependent calcium channel 0.0044 0.0286 0.0371
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0044 0.0286 0.034
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.005 0.0075
Echinococcus multilocularis 0.0063 0.0473 0.0473
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0031 0.0157 0.0175
Echinococcus multilocularis protoporphyrinogen oxidase 0.0063 0.0473 0.0473
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0387 0.368 0.4549
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0031 0.0157 0.0189
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0036 0.0071
Echinococcus multilocularis short transient receptor potential channel 6 0.0044 0.0286 0.0286
Echinococcus multilocularis lamin dm0 0.0058 0.0421 0.0421
Brugia malayi Cathepsin L-like precursor 0.002 0.005 0.0064
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0337 0.0337
Plasmodium falciparum thioredoxin reductase 0.0053 0.0373 0.0607
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0031 0.0157 0.0189
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0337 0.0437
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.001 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) norepinephrine transporter 0.0066 0.0507 0.0657
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Onchocerca volvulus 0.0052 0.0362 0.0809
Brugia malayi neuropeptide F receptor 0.0052 0.0362 0.0469
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0362 0.043
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.0549 0.0549
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0064 0.0064
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0632 0.2199
Mycobacterium ulcerans epimerase 0.0022 0.0066 0.0071
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0016 0.0004 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0036 0.0042
Echinococcus granulosus calcium activated potassium channel 0.0045 0.0296 0.0296
Toxoplasma gondii ABC1 family protein 0.0035 0.0194 0.1009
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0058 0.0058
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0058 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0011 0.003
Plasmodium vivax chloroquine resistance transporter, putative 0.0143 0.1266 0.2078
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Brugia malayi neuropeptide F receptor 0.0052 0.0362 0.0469
Brugia malayi beta-lactamase family protein 0.0035 0.0194 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0162 0.0695
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Plasmodium vivax vivapain-2 0.002 0.005 0.0075
Echinococcus granulosus ATP binding cassette sub family B 0.0025 0.0094 0.0094
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0031 0.0157 0.0189
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0011 0.0011
Schistosoma mansoni thyroid hormone receptor 0.004 0.0245 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0037 0.0213 0.1537
Trypanosoma brucei p-glycoprotein 0.0037 0.0213 0.073
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0031 0.0157 0.0175
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0245 0.0317
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0362 0.0362
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0245 0.0543
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0194 0.0218
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0785 0.7624 0.7624
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0071 0.0549 0.0712
Onchocerca volvulus Cathepsin L homolog 0.002 0.005 0.0102
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0058 0.0058
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.006 0.0441 0.0441
Loa Loa (eye worm) DR-78 0.0019 0.0036 0.0046
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0031 0.0157 0.0175
Leishmania major cathepsin L-like protease 0.002 0.005 0.0334
Leishmania major hypothetical protein, unknown function 0.0044 0.0286 0.2077
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0071 0.0553 0.2409
Echinococcus granulosus somatostatin receptor 0.0052 0.0362 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0233 0.1004
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0628 0.6075 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0373 0.0607
Onchocerca volvulus Cathepsin F homolog 0.002 0.005 0.0102
Echinococcus granulosus voltage dependent calcium channel 0.0648 0.6271 0.6271
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.001 0.001
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0062 0.0062
Loa Loa (eye worm) serotonin transporter b 0.0066 0.0507 0.0657
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 0.1286
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0612 0.2129
Schistosoma mansoni lipoxygenase 0.0129 0.1132 0.1345
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0079 0.0632 0.0722
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0246 0.0847
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0245 0.0317
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.006 0.0441 0.0524
Loa Loa (eye worm) hypothetical protein 0.0293 0.2748 0.3564
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0063 0.0473 0.0772
Plasmodium falciparum ABC transporter B family member 3, putative 0.0025 0.0094 0.0148
Plasmodium vivax glutathione reductase, putative 0.0152 0.136 0.2233
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0362 0.0362
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0031 0.0157 0.0189
Loa Loa (eye worm) calcium channel 0.0648 0.6271 0.8132
Echinococcus multilocularis Protein lozenge 0.0058 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0533
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0017 0.0014 0.0014
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0109 0.093 0.683
Giardia lamblia Multidrug resistance-associated protein 1 0.0037 0.0213 0.2251
Schistosoma mansoni lozenge 0.0058 0.0424 0.0503
Echinococcus multilocularis voltage dependent calcium channel 0.0648 0.6271 0.6271
Schistosoma mansoni coup transcription factor 0.004 0.0245 0.029
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0245 0.0543
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.0367 0.0476
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Brugia malayi multidrug resistance protein 3 0.0071 0.0553 0.0717
Echinococcus multilocularis thioredoxin glutathione reductase 0.0152 0.136 0.136
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0071 0.0553 0.0553
Schistosoma mansoni hypothetical protein 0.008 0.0639 0.0759
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0044 0.0286 0.0286
Entamoeba histolytica P-glyco protein 6, putative 0.0071 0.0553 0.2945
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0362 0.0362
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0245 0.029
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0058 0.0058
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0063 0.0473 0.0562
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 0.1286
Echinococcus granulosus neuropeptide receptor A26 0.1025 1 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0362 0.0469
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.0658 0.3558
Loa Loa (eye worm) hypothetical protein 0.0032 0.0167 0.0217
Echinococcus granulosus sex peptide receptor 0.0052 0.0362 0.0362
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0071 0.0553 0.2911
Schistosoma mansoni opsin-like receptor 0.0052 0.0362 0.043
Echinococcus multilocularis serotonin receptor 0.0185 0.1686 0.1686
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.139 0.1802
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0048 0.0327 0.0327
Brugia malayi cation channel family protein 0.0044 0.0286 0.0371
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0016 0.0004 0.0004
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0058 0.0075
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0062 0.0462 0.1247
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0025 0.0094 0.0103
Echinococcus granulosus two pore calcium channel protein 1 0.0044 0.0286 0.0286
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0016 0.0004 0.0004
Loa Loa (eye worm) voltage-dependent calcium channel 0.0206 0.1889 0.245
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Leishmania major protein kinase, putative 0.0017 0.0014 0.0072
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0036 0.0042
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1078 0.1281
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0004 0.0005
Brugia malayi follicle stimulating hormone receptor 0.0794 0.7712 1
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0286 0.0286
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0332 0.1146
Echinococcus granulosus hyperpolarization activated cyclic 0.006 0.0441 0.0441
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0337 0.0437
Mycobacterium ulcerans tryptophan-rich sensory protein 0.0293 0.2748 0.3152
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0362 0.0469
Schistosoma mansoni tar DNA-binding protein 0.0124 0.1078 0.1281
Schistosoma mansoni smdr1 0.0025 0.0094 0.0112
Leishmania major pentamidine resistance protein 1 0.0037 0.0213 0.1537
Onchocerca volvulus 0.0058 0.0421 0.0943
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0062 0.0254
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.1078 0.1398
Onchocerca volvulus 0.0462 0.4429 1
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0031 0.0157 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.093 0.4066
Schistosoma mansoni hypothetical protein 0.0865 0.8418 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0332 0.1146
Loa Loa (eye worm) hypothetical protein 0.0293 0.2748 0.3564
Echinococcus granulosus mitogen activated protein kinase 3 0.0109 0.093 0.093
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0025 0.0094 0.0111
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Schistosoma mansoni amine GPCR 0.0779 0.7567 0.8989
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0245 0.0317
Plasmodium falciparum multidrug resistance protein 1 0.0071 0.0553 0.0904
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0109 0.093 0.683
Mycobacterium tuberculosis Conserved protein 0.0035 0.0194 0.0235
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Onchocerca volvulus 0.0022 0.0064 0.0134
Toxoplasma gondii cytochrome p450 superfamily protein 0.0031 0.0157 0.0809
Brugia malayi hypothetical protein 0.0118 0.102 0.1322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Plasmodium vivax ataxin-2 like protein, putative 0.0055 0.0394 0.0642
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Brugia malayi hypothetical protein 0.0055 0.0394 0.0511
Echinococcus multilocularis tar DNA binding protein 0.0124 0.1078 0.1078
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0031 0.0157 0.0189
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.005 0.0064
Schistosoma mansoni myosin xvIII 0.0052 0.0362 0.043
Echinococcus granulosus ATP binding cassette sub family B 0.0024 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0063 0.0473 0.0614
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0672 0.11
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0058 0.0058
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0011 0.0014
Echinococcus multilocularis shaker cognate 0.0048 0.0327 0.0327
Brugia malayi Cathepsin L-like precursor 0.002 0.005 0.0064
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0058 0.0069
Mycobacterium tuberculosis Probable reductase 0.0348 0.3296 0.4073
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0152 0.136 0.1678
Trichomonas vaginalis taga, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0102 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0261 0.1128
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0037 0.0213 0.1537
Echinococcus granulosus multidrug resistance associated protein 7 0.0037 0.0213 0.0213
Schistosoma mansoni opsin-like receptor 0.0052 0.0362 0.043
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0025 0.0094 0.0476
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0005
Echinococcus multilocularis multidrug resistance protein 1 0.0071 0.0553 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0248 0.1071
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0036 0.0042
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0373 0.129
Loa Loa (eye worm) hypothetical protein 0.0331 0.3129 0.4058
Brugia malayi Serotonin receptor 0.0557 0.5366 0.6958
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0332 0.2415
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0025 0.0094 0.0244
Schistosoma mansoni two-pore calcium channel 0.0044 0.0286 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0233 0.1004
Onchocerca volvulus 0.002 0.005 0.0102
Echinococcus granulosus survival motor neuron protein 1 0.0256 0.2388 0.2388
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0362 0.0362
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0048 0.0327 0.0327
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Echinococcus granulosus multidrug resistance protein 1 0.0071 0.0553 0.0553
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.2055 0.2537
Loa Loa (eye worm) hypothetical protein 0.0022 0.0064 0.0083
Echinococcus multilocularis sterol regulatory element binding protein 0.0083 0.0669 0.0669
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 0.0897
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0362 0.0362
Brugia malayi nuclear receptor RXR 0.0021 0.0058 0.0075
Loa Loa (eye worm) hypothetical protein 0.0063 0.0473 0.0614
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0086 0.0357
Schistosoma mansoni neuropeptide receptor 0.0052 0.0362 0.043
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0286 0.0371
Echinococcus multilocularis conserved hypothetical protein 0.0044 0.0286 0.0286
Schistosoma mansoni multidrug resistance protein 0.0037 0.0213 0.0253
Trichomonas vaginalis esterase, putative 0.0035 0.0194 0.0835
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0016 0.0004 0.0005
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0131 0.1144 0.1144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0194 0.0231
Onchocerca volvulus 0.0293 0.2748 0.6202
Echinococcus granulosus g protein coupled receptor 0.0052 0.0362 0.0362
Schistosoma mansoni zinc finger protein 0.0019 0.0036 0.0042
Loa Loa (eye worm) hypothetical protein 0.0066 0.0507 0.0657
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0245 0.0317
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0194 0.0835
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0373 0.129
Toxoplasma gondii ABC transporter family protein 0.0025 0.0094 0.0476
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0071 0.0553 0.2409
Echinococcus granulosus chromobox protein 1 0.0072 0.0561 0.0561
Loa Loa (eye worm) glutathione reductase 0.0152 0.136 0.1764
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0362 0.0362
Schistosoma mansoni adenoreceptor 0.0052 0.0362 0.043
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.006 0.0441 0.0441
Schistosoma mansoni microtubule-associated protein tau 0.0758 0.7355 0.8737
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0245 0.0317
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Loa Loa (eye worm) ABC transporter 0.0025 0.0094 0.0122
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0066 0.0507 0.0657
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0068 0.0088
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0612 0.2129
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Onchocerca volvulus 0.0044 0.0284 0.0632
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0064 0.0098
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0058 0.0058
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0194 0.0252
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0362 0.043
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0031 0.0157 0.0189
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0362 0.043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0246 0.0246
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.008
Leishmania major cathepsin L-like protease 0.0077 0.0612 0.4486
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0016 0.0004 0.0006
Echinococcus multilocularis chromobox protein 1 0.0072 0.0561 0.0561
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0062 0.0306
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0194 0.0235
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.011 0.0463
Loa Loa (eye worm) hypothetical protein 0.0462 0.4429 0.5743
Schistosoma mansoni multidrug resistance protein 0.0025 0.0094 0.0112
Brugia malayi ABC transporter 0.0024 0.0086 0.0111
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0094 0.0785 0.4141
Giardia lamblia Hypothetical protein 0.0024 0.0086 0.0877
Brugia malayi PXA domain containing protein 0.0021 0.0058 0.0075
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0044 0.0286 0.0371
Plasmodium falciparum multidrug resistance-associated protein 2 0.0025 0.0094 0.0148
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0362 0.0469
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Echinococcus multilocularis potassium voltage gated channel protein 0.0048 0.0327 0.0327
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0373 0.0373
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0109 0.093 0.3242
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0362 0.0469
Toxoplasma gondii ABC transporter, putative 0.0025 0.0094 0.0476
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0031 0.0157 0.0189
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0052 0.0362 0.043
Schistosoma mansoni hypothetical protein 0.0049 0.0337 0.04
Echinococcus multilocularis cpg binding protein 0.0064 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0362 0.0469
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.001 0.001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0071 0.0553 0.2409
Brugia malayi intermediate filament protein 0.0058 0.0421 0.0546
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.001 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.139 0.1802
Trypanosoma cruzi multidrug resistance protein E, putative 0.0037 0.0213 0.073
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0194 0.0666
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0024 0.0086 0.0877
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0245 0.0317
Schistosoma mansoni multidrug resistance protein 0.0037 0.0213 0.0253
Echinococcus multilocularis potassium voltage gated channel protein 0.0044 0.0286 0.0286
Echinococcus multilocularis somatostatin receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.005 0.0064
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0362 0.0362
Schistosoma mansoni voltage-gated potassium channel 0.0048 0.0327 0.0388
Brugia malayi Dopamine receptor protein 1 0.0052 0.0362 0.0469
Schistosoma mansoni peptidase Clp (S14 family) 0.0094 0.0785 0.0932
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0016 0.0004 0.0005
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0016 0.0004 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.129
Loa Loa (eye worm) hypothetical protein 0.0293 0.2748 0.3564
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0245 0.0317
Trichomonas vaginalis ABC transporter, putative 0.0071 0.0553 0.2409
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0549 0.0652
Echinococcus multilocularis sex peptide receptor 0.0052 0.0362 0.0362
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0071 0.0553 0.2409
Echinococcus multilocularis sodium leak channel non selective protein 0.0044 0.0286 0.0286
Brugia malayi ion channel NompC 0.0044 0.0286 0.0371
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0155 0.1383 0.1793
Echinococcus granulosus cytochrome P450 2K1 0.0031 0.0157 0.0157
Brugia malayi RE15519p 0.0052 0.0362 0.0469
Schistosoma mansoni DNA helicase recq1 0.0021 0.0062 0.0074
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0053 0.0374 0.0609
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0246 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0208 0.0895
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0628 0.6075 1
Echinococcus granulosus sterol regulatory element binding protein 0.0083 0.0669 0.0669
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0245 0.0245
Onchocerca volvulus 0.0052 0.0362 0.0809
Loa Loa (eye worm) hypothetical protein 0.0058 0.0421 0.0546
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0252
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0245 0.0245
Brugia malayi putative neuropeptide receptor 0.0052 0.0362 0.0469
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0612 0.2129
Onchocerca volvulus 0.002 0.005 0.0102
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0066 0.0139
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Leishmania major ABC-thiol transporter 0.0037 0.0213 0.1537
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0245 0.0317
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0011 0.0013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0036 0.0036
Echinococcus granulosus GPCR family 2 0.0049 0.0337 0.0337
Echinococcus multilocularis protein patched 0.0083 0.0669 0.0669
Schistosoma mansoni nuclear receptor 0.0019 0.0036 0.0042
Echinococcus multilocularis multidrug resistance protein 1 0.0047 0.0317 0.0317
Loa Loa (eye worm) cysteine protease 0.002 0.005 0.0064
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0058 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0068 0.008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0362 0.043
Echinococcus granulosus potassium voltage gated channel protein 0.0048 0.0327 0.0327
Leishmania major cathepsin L-like protease 0.002 0.005 0.0334
Brugia malayi cytochrome P450 0.0031 0.0157 0.0203
Echinococcus granulosus cGMP dependent protein kinase 1 0.0017 0.0014 0.0014
Echinococcus granulosus g protein coupled receptor 0.0052 0.0362 0.0362
Trypanosoma cruzi cytochrome P450, putative 0.0079 0.0632 0.2199
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0473 0.0772
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0362 0.0362
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0071 0.0553 0.0553
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0071 0.0553 0.2409
Loa Loa (eye worm) RNA binding protein 0.0124 0.1078 0.1398
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Brugia malayi chromobox protein homolog 3 0.004 0.0248 0.0322
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0025 0.0094 0.0476
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0362 0.0362
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0031 0.0157 0.0175
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0628 0.6075 0.6974
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0063 0.0473 0.0772
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0086 0.0357
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Brugia malayi hypothetical protein 0.0127 0.1108 0.1436
Mycobacterium ulcerans dehydrogenase 0.0063 0.0473 0.0539
Loa Loa (eye worm) hypothetical protein 0.004 0.0245 0.0317
Schistosoma mansoni biogenic amine (5HT) receptor 0.0185 0.1686 0.2003
Schistosoma mansoni voltage-gated ion channel 0.0044 0.0286 0.034
Echinococcus granulosus allatostatin A receptor 0.0052 0.0362 0.0362
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0373 0.129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0332 0.1438
Echinococcus multilocularis ATP binding cassette sub family B 0.0025 0.0094 0.0094
Echinococcus granulosus multidrug resistance protein 1 0.0047 0.0317 0.0317
Schistosoma mansoni cpg binding protein 0.0061 0.0451 0.0536
Loa Loa (eye worm) hypothetical protein 0.0021 0.0058 0.0075
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0167 0.0167
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0094 0.0785 0.2123
Echinococcus multilocularis microtubule associated protein 2 0.0758 0.7355 0.7355
Schistosoma mansoni voltage-gated potassium channel 0.0135 0.1184 0.1407
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.006 0.0441 0.0524
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0031 0.0157 0.0175
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0286 0.0286
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0016 0.0004 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0246 0.0319
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 0.1155
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0025 0.0094 0.0122
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0362 0.0362
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.005 0.0199
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0031 0.0157 0.0175
Echinococcus granulosus chromobox protein 1 0.0072 0.0561 0.0561
Giardia lamblia Kinase, CMGC MAPK 0.0109 0.093 1
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0016 0.0004 0.0004
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0231 0.0794
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0071 0.0553 0.4047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0036 0.0046
Echinococcus granulosus neuropeptide receptor 0.0052 0.0362 0.0362
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0058 0.0235
Onchocerca volvulus 0.0052 0.0362 0.0809
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0362 0.0362
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0062 0.0073
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0286 0.034
Brugia malayi larval opioid receptor 0.0052 0.0362 0.0469
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0337 0.0337
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0058 0.0058
Echinococcus granulosus hypothetical protein 0.0809 0.7867 0.7867
Brugia malayi ORL1-like opioid receptor 0.0052 0.0362 0.0469
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0036 0.0046
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0362 0.0362
Plasmodium falciparum cGMP-dependent protein kinase 0.0017 0.0014 0.0016
Brugia malayi hypothetical protein 0.0019 0.0036 0.0046
Toxoplasma gondii histone lysine-specific demethylase 0.0063 0.0473 0.2488
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0109 0.0462
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0036 0.0046
Plasmodium vivax multidrug resistance protein 2, putative 0.0025 0.0094 0.0148
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.006 0.0441 0.0524
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0016 0.0004 0.0006
Echinococcus multilocularis chromobox protein 1 0.0072 0.0561 0.0561
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0373 0.129
Onchocerca volvulus 0.0293 0.2748 0.6202
Plasmodium falciparum thioredoxin reductase 0.0152 0.136 0.2233
Leishmania major p-glycoprotein e 0.0037 0.0213 0.1537
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.1 0.5285
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0031 0.0157 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0138 0.0585
Schistosoma mansoni lipoxygenase 0.0091 0.0746 0.0886
Toxoplasma gondii hypothetical protein 0.0044 0.0286 0.1494
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0286 0.0286
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0058 0.0075
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0362 0.043
Brugia malayi Dopamine receptor protein 2 0.0052 0.0362 0.0469
Echinococcus multilocularis Niemann Pick C1 protein 0.0193 0.1759 0.1759
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0094 0.0785 0.1286
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0062 0.0062
Brugia malayi hypothetical protein 0.0021 0.0058 0.0075
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0362 0.043
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0362 0.0362
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0011 0.0014
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0062 0.0062
Trichomonas vaginalis set domain proteins, putative 0.0246 0.2282 1
Schistosoma mansoni chromobox protein 0.0072 0.0561 0.0666
Onchocerca volvulus 0.0063 0.0473 0.106
Brugia malayi hypothetical protein 0.0021 0.0058 0.0075
Schistosoma mansoni calcium-activated potassium channel 0.0044 0.0286 0.034
Brugia malayi G protein-coupled receptor 0.0052 0.0362 0.0469
Loa Loa (eye worm) ABC transporter 0.0025 0.0094 0.0122
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0194 0.0231
Echinococcus multilocularis GPCR, family 2 0.0049 0.0337 0.0337
Onchocerca volvulus 0.0293 0.2748 0.6202
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0031 0.0157 0.0175
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0245 0.0543
Onchocerca volvulus 0.0071 0.0553 0.124
Loa Loa (eye worm) hypothetical protein 0.0044 0.0286 0.0371
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0362 0.0469
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0058 0.0075
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0063 0.0473 0.0473
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0062 0.0254
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0362 0.043
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0373 0.0607
Giardia lamblia Multidrug resistance-associated protein 1 0.0037 0.0213 0.2251
Echinococcus multilocularis neuropeptide s receptor 0.1025 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.005 0.0059
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0011 0.0024
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0194 0.0666
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0337 0.0437
Loa Loa (eye worm) hypothetical protein 0.0106 0.0902 0.117
Echinococcus multilocularis two pore calcium channel protein 2 0.0044 0.0286 0.0286
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0373 0.1955
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0155 0.1383 0.1383
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0031 0.0157 0.0175
Schistosoma mansoni smdr2 0.0071 0.0553 0.0657
Chlamydia trachomatis protoporphyrinogen oxidase 0.0063 0.0473 0.0772
Loa Loa (eye worm) ctsf protein 0.002 0.005 0.0064
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0058 0.0069
Echinococcus multilocularis two pore calcium channel protein 1 0.0044 0.0286 0.0286
Echinococcus granulosus translocator protein 0.0293 0.2748 0.2748
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0373 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0245 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.005 0.0199
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0102 0.0429
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0071 0.0553 0.0904
Loa Loa (eye worm) hypothetical protein 0.0052 0.0362 0.0469
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0025 0.0094 0.0662
Brugia malayi hypothetical protein 0.0052 0.0362 0.0469
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0362 0.0362
Echinococcus granulosus multidrug resistance protein 1 0.0071 0.0553 0.0553
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0011 0.0024
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0063 0.0473 0.0772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0138 0.0585
Echinococcus granulosus Protein patched homolog 1 0.0083 0.0669 0.0669
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0231 0.0231

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.7943 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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