Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neuroligin | 0.0246 | 0.1188 | 0.0835 |
Loa Loa (eye worm) | carboxylesterase | 0.1457 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.1188 | 0.114 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0246 | 0.1188 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1457 | 1 | 1 |
Onchocerca volvulus | 0.0246 | 0.1188 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0246 | 0.1188 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0246 | 0.1188 | 0.0835 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0246 | 0.1188 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.1188 | 0.114 |
Echinococcus multilocularis | acetylcholinesterase | 0.1457 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0246 | 0.1188 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Onchocerca volvulus | 0.0246 | 0.1188 | 1 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0246 | 0.1188 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1457 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.1188 | 0.114 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0246 | 0.1188 | 0.0835 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0246 | 0.1188 | 0.0835 |
Loa Loa (eye worm) | matrixin family protein | 0.009 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Brugia malayi | Carboxylesterase family protein | 0.1457 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0246 | 0.1188 | 0.0835 |
Echinococcus granulosus | neuroligin | 0.0246 | 0.1188 | 0.0835 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.1188 | 0.114 |
Loa Loa (eye worm) | carboxylesterase | 0.0246 | 0.1188 | 0.1188 |
Echinococcus granulosus | carboxylesterase 5A | 0.1457 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0246 | 0.1188 | 0.1188 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0246 | 0.1188 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1457 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1188 | 0.1188 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0246 | 0.1188 | 0.5 |
Onchocerca volvulus | 0.0246 | 0.1188 | 1 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.1457 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1457 | 1 | 1 |
Onchocerca volvulus | 0.0246 | 0.1188 | 1 | |
Echinococcus granulosus | acetylcholinesterase | 0.1457 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1457 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0246 | 0.1188 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.1457 | 1 | 1 |
Onchocerca volvulus | 0.0246 | 0.1188 | 1 | |
Brugia malayi | hypothetical protein | 0.0246 | 0.1188 | 0.114 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.