Detailed information for compound 808430

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 496.623 | Formula: C20H24N4O5S3
  • H donors: 1 H acceptors: 6 LogP: 2.68 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1c2CCN(Cc2sc1S(=O)(=O)NCCC1=CCCCC1)C(=O)c1csnn1
  • InChi: 1S/C20H24N4O5S3/c1-29-19(26)17-14-8-10-24(18(25)15-12-30-23-22-15)11-16(14)31-20(17)32(27,28)21-9-7-13-5-3-2-4-6-13/h5,12,21H,2-4,6-11H2,1H3
  • InChiKey: REDQAXCJMDLGQZ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0064 0.0437
Brugia malayi nuclear receptor NHR-88 0.0012 0.008 0.0127
Onchocerca volvulus Putative cubilin 0.0028 0.0299 0.0436
Mycobacterium tuberculosis Probable sulfatase 0.0014 0.0111 0.0103
Schistosoma mansoni notch 0.0028 0.0299 0.0616
Mycobacterium ulcerans arylsulfatase AtsB 0.0014 0.0111 0.0103
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0742 0.13
Loa Loa (eye worm) helicase 0.0008 0.0032 0.0039
Schistosoma mansoni alpha-glucosidase 0.0048 0.0558 0.1147
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.0213
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0008 0.0026 0.0044
Loa Loa (eye worm) zinc metallopeptidase 4 0.0008 0.0025 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0171 0.024
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Onchocerca volvulus 0.0016 0.013 0.0182
Mycobacterium tuberculosis Conserved protein 0.0016 0.0138 0.013
Chlamydia trachomatis glutamate symporter 0.0302 0.3956 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0006 0.0009 0.0015
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0017 0.0152 0.0313
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0008 0.0032 0.0056
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Loa Loa (eye worm) hypothetical protein 0.0024 0.024 0.0339
Echinococcus multilocularis ornithine aminotransferase 0.0008 0.0026 0.0045
Trichomonas vaginalis chromobox protein, putative 0.003 0.0327 0.0477
Onchocerca volvulus 0.0028 0.0299 0.0436
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Brugia malayi ATP-citrate synthase 0.0041 0.0476 0.0804
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0066 0.0115
Leishmania major hypothetical protein, conserved 0.0016 0.0138 0.0837
Echinococcus multilocularis cpg binding protein 0.0016 0.0131 0.023
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0206 0.2679 0.4695
Loa Loa (eye worm) hypothetical protein 0.0022 0.0219 0.031
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0187 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Trypanosoma cruzi PAB1-binding protein , putative 0.0009 0.0037 0.0181
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.001 0.0055 0.0097
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.008 0.0127
Echinococcus multilocularis neurogenic locus protein delta 0.0028 0.0299 0.0525
Onchocerca volvulus Putative protein 0.0028 0.0301 0.0439
Echinococcus granulosus leukotriene A 4 hydrolase 0.0017 0.0152 0.0267
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0009 0.0044 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Echinococcus granulosus nmda type glutamate receptor 0.0063 0.0769 0.1348
Brugia malayi Calcium binding EGF domain containing protein 0.0028 0.0299 0.0502
Mycobacterium tuberculosis Conserved protein 0.0028 0.0301 0.0293
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0193
Echinococcus multilocularis tar DNA binding protein 0.0031 0.034 0.0597
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0063 0.0769 0.1107
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0009 0.0044 0.0078
Trypanosoma brucei Aminopeptidase M1, putative 0.0049 0.0576 0.1194
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0134 0.171 0.2997
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0027 0.0286 0.1791
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0032 0.0186
Echinococcus multilocularis tyrosine kinase 0.0063 0.0769 0.1348
Echinococcus granulosus neurogenic locus notch protein 4 0.0028 0.0299 0.0525
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.008 0.0139
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0064 0.0777 0.1362
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Onchocerca volvulus 0.0016 0.0138 0.0195
Plasmodium falciparum glutathione reductase 0.0024 0.0247 0.1538
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.008 0.0139
Brugia malayi hypothetical protein 0.0017 0.0152 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Schistosoma mansoni metabotropic glutamate receptor 0.0191 0.2477 0.5097
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0247 0.1538
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0005 0.0011
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0017 0.0152 0.0926
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0005 0.0011
Trypanosoma brucei ISWI complex protein 0.0007 0.0022 0.0027
Trypanosoma brucei PAB1-binding protein , putative 0.0009 0.0037 0.0059
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Loa Loa (eye worm) hypothetical protein 0.0023 0.0232 0.0329
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0055 0.0069
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.008 0.0139
Echinococcus multilocularis GPCR, family 3, C terminal 0.0053 0.0627 0.1099
Echinococcus granulosus glutamate receptor 2 0.0142 0.1824 0.3197
Mycobacterium ulcerans esterase/lipase LipP 0.0016 0.0138 0.013
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.016 0.0224
Trichomonas vaginalis sucrase-isomaltase, putative 0.0012 0.0086 0.0116
Plasmodium falciparum thioredoxin reductase 0.0024 0.0247 0.1538
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0247 0.0509
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0101 0.127 0.2654
Loa Loa (eye worm) hypothetical protein 0.0081 0.1005 0.1449
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Entamoeba histolytica heat shock transcription factor, putative 0.0034 0.0372 0.2878
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0027 0.0286 0.0704
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Entamoeba histolytica phosphofructokinase, putative 0.0101 0.127 1
Loa Loa (eye worm) glutathione reductase 0.007 0.0859 0.1238
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0188 0.027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.008 0.0127
Trichomonas vaginalis chromobox protein, putative 0.0008 0.0032 0.0035
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0103 0.1302 0.1294
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Trichomonas vaginalis succinate thiokinase a subunit 0.0008 0.0031 0.0033
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0017 0.0152 0.0926
Schistosoma mansoni chromodomain helicase DNA binding protein 0.001 0.0055 0.0113
Echinococcus multilocularis aminopeptidase N 0.0105 0.1319 0.2311
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0016 0.0137 0.0128
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0123 0.156 1
Schistosoma mansoni sulfide quinone reductase 0.0006 0.0009 0.0018
Brugia malayi Muscleblind-like protein 0.0051 0.0599 0.1015
Onchocerca volvulus 0.0008 0.0032 0.0035
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0083 0.1035 0.1028
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0013 0.0092 0.0176
Echinococcus multilocularis lamin dm0 0.0022 0.0219 0.0384
Entamoeba histolytica heat shock transcription factor, putative 0.0034 0.0372 0.2878
Brugia malayi hypothetical protein 0.0218 0.2838 0.4842
Echinococcus granulosus nmda type glutamate receptor 0.0147 0.189 0.3313
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0009 0.0044 0.023
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0247 0.1538
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0016 0.0138 0.0285
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0032 0.0148
Onchocerca volvulus 0.0063 0.0769 0.1141
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0008 0.0026 0.0017
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0009 0.0044 0.023
Echinococcus multilocularis lamin 0.0022 0.0219 0.0384
Echinococcus multilocularis Aminotransferase class III 0.0008 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Schistosoma mansoni tar DNA-binding protein 0.0031 0.034 0.07
Onchocerca volvulus 0.0008 0.0032 0.0035
Schistosoma mansoni microtubule-associated protein tau 0.0234 0.3048 0.6272
Mycobacterium ulcerans hypothetical protein 0.0028 0.0301 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0138 0.0837
Loa Loa (eye worm) Notch2 0.0028 0.0299 0.0426
Schistosoma mansoni cpg binding protein 0.0016 0.0131 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Echinococcus multilocularis NMDA receptor 0.0064 0.0777 0.1362
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.016 0.028
Loa Loa (eye worm) hypothetical protein 0.0051 0.0599 0.086
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Echinococcus multilocularis neutral amino acid transporter A 0.0302 0.3956 0.6933
Loa Loa (eye worm) CHromoDomain protein family member 0.001 0.0055 0.0072
Schistosoma mansoni hypothetical protein 0.0301 0.3942 0.8112
Brugia malayi Peptidase family M1 containing protein 0.0017 0.0152 0.0251
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0011 0.002
Entamoeba histolytica phosphofructokinase, putative 0.0101 0.127 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0101 0.127 0.1832
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0013 0.0092 0.0125
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Trypanosoma cruzi trypanothione reductase, putative 0.007 0.0859 0.5485
Loa Loa (eye worm) glutamate receptor 0.0128 0.1631 0.2356
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0006 0.0009 0.0015
Echinococcus granulosus succinyl coenzyme A synthetase alpha subunit 0.0008 0.0031 0.0054
Loa Loa (eye worm) hypothetical protein 0.0024 0.024 0.0339
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.008 0.0139
Brugia malayi Delta serrate ligand family protein 0.0028 0.0299 0.0502
Brugia malayi Associated with TFs and helicases family protein 0.0008 0.0032 0.0046
Brugia malayi ecdysteroid receptor 0.0012 0.008 0.0127
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Trichomonas vaginalis chromobox protein, putative 0.0008 0.0032 0.0035
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Trichomonas vaginalis set domain proteins, putative 0.0506 0.6674 1
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0063 0.0769 0.1348
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0027 0.0286 0.2203
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0008 0.0032 0.0056
Giardia lamblia Tyrosyl-tRNA synthetase 0.0015 0.0126 0.4041
Entamoeba histolytica hypothetical protein 0.0008 0.0032 0.0186
Trichomonas vaginalis chromobox protein, putative 0.005 0.0592 0.0876
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.008 0.0461
Brugia malayi beta-lactamase family protein 0.0016 0.0138 0.0227
Echinococcus multilocularis excitatory amino acid transporter 2 0.0302 0.3956 0.6933
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0049 0.0576 0.3659
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Loa Loa (eye worm) hypothetical protein 0.0013 0.0092 0.0126
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0017 0.0152 0.0926
Echinococcus multilocularis neuropeptide receptor A26 0.0159 0.2046 0.3586
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0247 0.1538
Trypanosoma brucei beta lactamase 0.0362 0.476 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0342 0.0487
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0016 0.0138 0.0227
Mycobacterium ulcerans hydrolase 0.0014 0.0111 0.0103
Echinococcus multilocularis muscleblind protein 1 0.0051 0.0599 0.105
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0013 0.0092 0.0125
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0017 0.0152 0.0926
Mycobacterium ulcerans hypothetical protein 0.0028 0.0301 0.0293
Schistosoma mansoni methionyl-tRNA synthetase 0.0012 0.008 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0018 0.0162 0.023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0444 0.5855 0.8479
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0777 0.1362
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0286 0.0417
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0247 0.1538
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0049 0.0576 0.101
Mycobacterium ulcerans L-lysine aminotransferase 0.0008 0.0026 0.0017
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0008 0.0026 0.0017
Echinococcus granulosus muscleblind protein 0.0051 0.0599 0.105
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.016 0.028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Loa Loa (eye worm) programmed cell death 8 0.0006 0.0009 0.0005
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0302 0.3956 0.6933
Trichomonas vaginalis Heterochromatin protein, putative 0.0008 0.0032 0.0035
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0049 0.0576 0.1186
Loa Loa (eye worm) hypothetical protein 0.0014 0.0111 0.0154
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0006 0.0009 0.0015
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Toxoplasma gondii aminopeptidase n, putative 0.0017 0.0152 0.0926
Echinococcus granulosus survival motor neuron protein 1 0.0093 0.1162 0.2037
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.008 0.0127
Echinococcus granulosus FTZ F1 alpha 0.0012 0.008 0.0139
Loa Loa (eye worm) phosphofructokinase 0.0101 0.127 0.1832
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0008 0.0026 0.0036
Loa Loa (eye worm) 6-phosphofructokinase 0.0101 0.127 0.1832
Schistosoma mansoni hypothetical protein 0.0098 0.1227 0.2526
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.008 0.0139
Schistosoma mansoni tyrosine kinase 0.0063 0.0769 0.1582
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Mycobacterium ulcerans glyoxalase GloA 0.0028 0.0301 0.0293
Echinococcus multilocularis tyrosyl tRNA synthetase 0.0027 0.0284 0.0497
Leishmania major tyrosyl-tRNA synthetase, putative 0.0015 0.0126 0.0757
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.008 0.0164
Echinococcus granulosus notch 0.0028 0.0299 0.0525
Echinococcus granulosus metabotropic glutamate receptor 5 0.0433 0.5706 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0008 0.0032 0.0046
Trichomonas vaginalis inositol monophosphatase, putative 0.0018 0.0162 0.023
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0206 0.2679 0.4695
Echinococcus granulosus delta-like protein 1 0.0028 0.0299 0.0525
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0064 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Schistosoma mansoni metabotropic glutamate receptor 0.0305 0.3998 0.8227
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0193
Entamoeba histolytica aminopeptidase, putative 0.0049 0.0576 0.45
Loa Loa (eye worm) hypothetical protein 0.0022 0.0217 0.0306
Echinococcus multilocularis geminin 0.0301 0.3942 0.6909
Schistosoma mansoni sulfide quinone reductase 0.0006 0.0009 0.0018
Brugia malayi Animal haem peroxidase family protein 0.0218 0.2838 0.4842
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0017 0.0152 0.0313
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0017 0.0152 0.0926
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Brugia malayi Excitatory amino acid transporter 0.0302 0.3956 0.6753
Loa Loa (eye worm) animal heme peroxidase 0.0218 0.2838 0.4106
Echinococcus granulosus microtubule associated protein 2 0.0234 0.3048 0.5341
Echinococcus granulosus GPCR family 2 0.0018 0.016 0.028
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0018 0.0161 0.0266
Loa Loa (eye worm) hypothetical protein 0.0433 0.5706 0.8262
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0247 0.0239
Schistosoma mansoni peroxidasin 0.0218 0.2838 0.584
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0302 0.3956 0.6933
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0247 0.0413
Loa Loa (eye worm) hypothetical protein 0.0023 0.0232 0.0329
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0027 0.0286 0.1791
Echinococcus granulosus zinc finger protein 0.001 0.006 0.0105
Echinococcus multilocularis glutamate synthase 0.0006 0.0009 0.0015
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0247 0.0433
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0017 0.0152 0.0926
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0086 0.0116
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0006 0.0009 0.0015
Plasmodium vivax glutathione reductase, putative 0.007 0.0859 0.5485
Loa Loa (eye worm) hypothetical protein 0.0034 0.0381 0.0544
Echinococcus granulosus chromobox protein 1 0.005 0.0592 0.1038
Plasmodium vivax methionine-tRNA ligase, putative 0.0012 0.008 0.0461
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Schistosoma mansoni survival motor neuron protein 0.0019 0.0175 0.0361
Echinococcus multilocularis X box binding protein 1 0.0098 0.1227 0.2151
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0006 0.0009 0.0015
Echinococcus granulosus neurogenic locus notch protein 0.0028 0.0299 0.0525
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0247 0.0358
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0086 0.0116
Brugia malayi Heterochromatin protein 1 0.005 0.0592 0.1003
Schistosoma mansoni slit 0.0028 0.0299 0.0616
Brugia malayi hypothetical protein 0.0008 0.0032 0.0046
Brugia malayi Blistered cuticle protein 3 0.0218 0.2838 0.4842
Echinococcus multilocularis Chromo domain 0.0008 0.0032 0.0056
Trypanosoma cruzi tyrosyl-tRNA synthetase, putative 0.0015 0.0126 0.0757
Brugia malayi Latrophilin receptor protein 2 0.0018 0.016 0.0264
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0017 0.0155 0.0272
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0362 0.476 0.4755
Loa Loa (eye worm) hypothetical protein 0.0087 0.1089 0.157
Loa Loa (eye worm) hypothetical protein 0.0014 0.0111 0.0154
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0008 0.0026 0.0036
Plasmodium falciparum glyoxalase I 0.0028 0.0301 0.1887
Loa Loa (eye worm) hypothetical protein 0.0093 0.1162 0.1677
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0017 0.0152 0.0267
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Echinococcus granulosus neurogenic locus notch protein 0.0028 0.0299 0.0525
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0019 0.0175 0.029
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0008 0.0032 0.0056
Echinococcus granulosus neutral amino acid transporter A 0.0302 0.3956 0.6933
Brugia malayi Receptor family ligand binding region containing protein 0.0063 0.0769 0.1305
Onchocerca volvulus 0.0022 0.0219 0.0316
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0012 0.008 0.0567
Loa Loa (eye worm) thioredoxin reductase 0.007 0.0859 0.1238
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0138 0.0195
Brugia malayi Animal haem peroxidase family protein 0.0218 0.2838 0.4842
Echinococcus granulosus slit 2 protein 0.0028 0.0299 0.0525
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0083 0.1035 0.6035
Brugia malayi hypothetical protein 0.0201 0.2602 0.4438
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Schistosoma mansoni ap endonuclease 0.0009 0.0044 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0082 0.011
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0053 0.0627 0.0928
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0027 0.0286 0.0704
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0247 0.0604
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.001 0.0052 0.0065
Schistosoma mansoni alpha-glucosidase 0.0048 0.0558 0.1147
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0028 0.0301 0.0293
Loa Loa (eye worm) hypothetical protein 0.0016 0.013 0.0181
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0083 0.1035 0.2601
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.008 0.0127
Toxoplasma gondii ATP-citrate lyase, putative 0.0041 0.0476 0.3012
Echinococcus multilocularis neutral alpha glucosidase AB 0.0012 0.0086 0.0151
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0393 0.5175 0.9069
Plasmodium falciparum heterochromatin protein 1 0.0008 0.0032 0.0151
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0017 0.0152 0.0213
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0673 0.1141
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0086 0.0116
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0009 0.0044 0.0056
Echinococcus granulosus tumor protein p63 0.0115 0.1453 0.2546
Schistosoma mansoni succinyl-CoA synthetase-related 0.0008 0.0031 0.0064
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0008 0.0033 0.0058
Brugia malayi beta-lactamase family protein 0.0016 0.0138 0.0227
Schistosoma mansoni hypothetical protein 0.0053 0.0627 0.1291
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0023 0.003
Mycobacterium tuberculosis Probable hydrolase 0.0016 0.0138 0.013
Brugia malayi beta-lactamase 0.0016 0.0138 0.0227
Plasmodium vivax 6-phosphofructokinase, putative 0.0027 0.0286 0.1791
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0012 0.008 0.0151
Echinococcus multilocularis aminoacyl tRNA synthase complex interacting 0.0012 0.008 0.0141
Brugia malayi Receptor family ligand binding region containing protein 0.0116 0.1474 0.251
Giardia lamblia Hypothetical protein 0.0014 0.0111 0.3536
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0301 0.0439
Brugia malayi exodeoxyribonuclease III family protein 0.0009 0.0044 0.0066
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0063 0.0769 0.1305
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.008 0.0139
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0206 0.2679 0.4695
Echinococcus multilocularis excitatory amino acid transporter 3 0.0302 0.3956 0.6933
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.008 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Plasmodium vivax succinyl-CoA synthetase alpha subunit, putative 0.0008 0.0031 0.0143
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0032 0.0186
Echinococcus multilocularis glutamate receptor 2 0.0206 0.2679 0.4695
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, beta chain PheT 0.0012 0.008 0.0072
Brugia malayi Sulfatase family protein 0.0014 0.0111 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Brugia malayi TATA binding protein associated factor 0.0017 0.0152 0.0251
Schistosoma mansoni inositol monophosphatase 0.0018 0.0162 0.0333
Echinococcus multilocularis neutral amino acid transporter A 0.0302 0.3956 0.6933
Schistosoma mansoni ATP-binding cassette transporter 0.0143 0.1833 0.3772
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0028 0.0301 0.0429
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0006 0.0009 0.0015
Brugia malayi steroid hormone receptor 0.0012 0.008 0.0127
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0247 0.1538
Loa Loa (eye worm) animal heme peroxidase 0.0218 0.2838 0.4106
Schistosoma mansoni endothelin-converting enzyme-related 0.0008 0.0025 0.0051
Plasmodium vivax 6-phosphofructokinase, putative 0.0027 0.0286 0.1791
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.008 0.0139
Entamoeba histolytica hypothetical protein 0.0012 0.008 0.0567
Schistosoma mansoni ATP-citrate synthase 0.0035 0.0391 0.0805
Brugia malayi MH2 domain containing protein 0.0041 0.0463 0.0782
Schistosoma mansoni bromodomain containing protein 0.0031 0.0343 0.0706
Loa Loa (eye worm) bromodomain containing protein 0.0009 0.0037 0.0046
Treponema pallidum glutamate transporter 0.0134 0.171 1
Loa Loa (eye worm) animal heme peroxidase 0.0218 0.2838 0.4106
Echinococcus multilocularis fibropellin Ia 0.0028 0.0299 0.0525
Trypanosoma brucei glucosidase, putative 0.0012 0.0086 0.0163
Loa Loa (eye worm) hypothetical protein 0.0011 0.0066 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0074 0.0098
Mycobacterium tuberculosis Probable aminotransferase 0.0054 0.065 0.0642
Echinococcus multilocularis neurogenic locus notch protein 0.0028 0.0299 0.0525
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Leishmania major 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0028 0.0299 0.0502
Toxoplasma gondii glyoxalase family protein 0.0028 0.0301 0.1887
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0006 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0056 0.0665 0.0956
Echinococcus granulosus excitatory amino acid transporter 2 0.0302 0.3956 0.6933
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0219 0.031
Echinococcus granulosus Chromobox protein 3 0.0008 0.0032 0.0056
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0162 0.0987
Loa Loa (eye worm) animal heme peroxidase 0.0218 0.2838 0.4106
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0008 0.0025 0.0051
Toxoplasma gondii exonuclease III APE 0.0009 0.0044 0.023
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0006 0.0009 0.0015
Trypanosoma brucei aminopeptidase, putative 0.0017 0.0152 0.0302
Plasmodium falciparum ataxin-2 like protein, putative 0.0009 0.0037 0.0181
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0327 0.0477
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Echinococcus granulosus beta LACTamase domain containing family member 0.0016 0.0138 0.0243
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0433 0.5706 1
Echinococcus granulosus 6 phosphofructokinase 0.0101 0.127 0.2225
Echinococcus multilocularis zinc finger protein 0.001 0.006 0.0105
Toxoplasma gondii ABC1 family protein 0.0016 0.0138 0.0837
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0011 0.002
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.016 0.2059 0.2052
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0006 0.0009 0.0006
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0012 0.0086 0.0615
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.001 0.0055 0.0069
Schistosoma mansoni neprilysin-2 (M13 family) 0.0016 0.0134 0.0276
Brugia malayi Glutamate receptor 2 precursor 0.0143 0.1833 0.3123
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0219 0.0366
Leishmania major extracellular receptor, putative 0.0063 0.0769 0.4902
Loa Loa (eye worm) RGC/RGC protein kinase 0.0063 0.0769 0.1107
Schistosoma mansoni thyroid hormone receptor 0.0012 0.008 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.008 0.0127
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0162 0.0322
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Toxoplasma gondii EGF family domain-containing protein 0.0028 0.0299 0.1874
Brugia malayi hypothetical protein 0.0014 0.0111 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Echinococcus granulosus atrial natriuretic peptide receptor 0.0063 0.0769 0.1348
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0086 0.05
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Loa Loa (eye worm) RGC/RGC protein kinase 0.0063 0.0769 0.1107
Echinococcus granulosus neurogenic locus protein delta 0.0028 0.0299 0.0525
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0134 0.171 0.2997
Schistosoma mansoni methyl-cpg binding protein mbd 0.0008 0.0033 0.0068
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0013 0.0092 0.0662
Echinococcus multilocularis protein jagged 2 0.0028 0.0299 0.0525
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0027 0.0286 0.0417
Schistosoma mansoni ap endonuclease 0.0009 0.0044 0.0091
Echinococcus granulosus glutamate synthase 0.0006 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0436 0.0623
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0032 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0887 0.1824
Brugia malayi Animal haem peroxidase family protein 0.0218 0.2838 0.4842
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0031 0.0342 0.0333
Onchocerca volvulus 0.0022 0.0217 0.0312
Brugia malayi succinyl-CoA ligase [GDP-forming] alpha-chain, mitochindrial 0.0008 0.0031 0.0043
Toxoplasma gondii aminopeptidase N protein 0.0017 0.0152 0.0926
Schistosoma mansoni hypothetical protein 0.001 0.0056 0.0116
Onchocerca volvulus 0.0012 0.008 0.0106
Onchocerca volvulus 0.0017 0.0152 0.0216
Echinococcus granulosus aminopeptidase N 0.0105 0.1319 0.2311
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0008 0.0032 0.0056
Onchocerca volvulus 0.0014 0.0109 0.015
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0008 0.0026 0.0017
Echinococcus granulosus neuropeptide receptor A26 0.0159 0.2046 0.3586
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0138 0.0837
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Echinococcus granulosus chromobox protein 1 0.005 0.0592 0.1038
Schistosoma mansoni thyroid hormone receptor 0.0012 0.008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Plasmodium vivax 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0072 0.0887 0.1826
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0012 0.0086 0.0117
Schistosoma mansoni nuclear hormone receptor 0.0012 0.008 0.0164
Leishmania major succinyl-CoA synthetase alpha subunit, putative 0.0008 0.0031 0.0143
Schistosoma mansoni glutamate receptor kainate 0.0143 0.1833 0.3771
Echinococcus multilocularis GPCR, family 2 0.0018 0.016 0.028
Treponema pallidum NADH oxidase 0.0024 0.0247 0.1401
Echinococcus multilocularis chromobox protein 1 0.005 0.0592 0.1038
Schistosoma mansoni glutamate synthase 0.0006 0.0009 0.0018
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0016 0.0138 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Schistosoma mansoni hypothetical protein 0.0064 0.0777 0.1599
Mycobacterium ulcerans hypothetical protein 0.0054 0.065 0.0642
Echinococcus multilocularis lysosomal alpha glucosidase 0.0055 0.066 0.1157
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0138 0.0273
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0187 0.0268
Toxoplasma gondii tRNA binding domain-containing protein 0.0012 0.008 0.0461
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Echinococcus multilocularis survival motor neuron protein 1 0.0093 0.1162 0.2037
Loa Loa (eye worm) histone methyltransferase 0.0007 0.0011 0.0009
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0064 0.0777 0.1362
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0081 0.1005 0.1495
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.008 0.0107
Brugia malayi Thioredoxin reductase 0.007 0.0859 0.146
Echinococcus multilocularis microtubule associated protein 2 0.0234 0.3048 0.5341
Echinococcus granulosus excitatory amino acid transporter 3 0.0302 0.3956 0.6933
Giardia lamblia Sgs1 DNA helicase, putative 0.0008 0.0032 0.0792
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.008 0.0107
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0028 0.0301 0.0506
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0008 0.0032 0.0056
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0777 0.4954
Echinococcus granulosus aminoacyl tRNA synthase complex interacting 0.0012 0.008 0.0141
Loa Loa (eye worm) aminopeptidase N 0.0049 0.0576 0.0827
Echinococcus multilocularis protein jagged 1 0.0028 0.0299 0.0525
Brugia malayi notch-like transmembrane receptor 0.0028 0.0299 0.0502
Toxoplasma gondii succinyl-CoA-synthetase alpha SCSA 0.0008 0.0031 0.0143
Toxoplasma gondii 6-phosphofructokinase 0.0027 0.0286 0.1791
Schistosoma mansoni chromobox protein 0.005 0.0592 0.1219
Schistosoma mansoni chromobox protein 0.0008 0.0032 0.0066
Onchocerca volvulus 0.0218 0.2838 0.4245
Schistosoma mansoni peroxidasin 0.0218 0.2838 0.584
Mycobacterium ulcerans acetylornithine aminotransferase 0.0008 0.0026 0.0017
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0016 0.0138 0.013
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0247 0.1538
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.0301 0.0293
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.0603 0.7966 0.7964
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.008 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0101 0.127 0.1892
Mycobacterium ulcerans hypothetical protein 0.0028 0.0301 0.0293
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0016 0.0138 0.0193
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0178 0.2298 0.2291
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0008 0.0025 0.0051
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0005 0.001
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0028 0.0301 0.062
Mycobacterium tuberculosis Conserved protein 0.0028 0.0301 0.0293
Echinococcus granulosus excitatory amino acid transporter 2 0.0302 0.3956 0.6933
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0005 0.001
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.0329
Trypanosoma cruzi aminopeptidase, putative 0.0049 0.0576 0.3659
Entamoeba histolytica tyrosyl-tRNA synthetase, putative 0.0015 0.0126 0.0931
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0012 0.0079 0.0163
Brugia malayi Animal haem peroxidase family protein 0.0218 0.2838 0.4842
Loa Loa (eye worm) PHD-finger family protein 0.001 0.0056 0.0073
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Schistosoma mansoni glutamate receptor NMDA 0.0143 0.1833 0.3771
Leishmania major trypanothione reductase 0.007 0.0859 0.5485
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0009 0.0044 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.008 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0008 0.0032 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0193
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0074 0.0098
Brugia malayi Protein cec-1. 0.0008 0.0032 0.0046
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0018 0.0162 0.1214
Plasmodium vivax glyoxalase I, putative 0.0028 0.0301 0.1887
Schistosoma mansoni coup transcription factor 0.0012 0.008 0.0164
Brugia malayi Cadherin domain containing protein 0.0028 0.0299 0.0502
Trichomonas vaginalis succinate thiokinase a subunit 0.0008 0.0031 0.0033
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0017 0.0152 0.0926
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0138 0.0837
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0008 0.0025 0.0051
Toxoplasma gondii peptidase family M13 protein 0.0031 0.0342 0.2147
Echinococcus multilocularis chromobox protein 2 0.0008 0.0032 0.0056
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.0086 0.0116
Treponema pallidum methionyl-tRNA synthetase 0.0012 0.008 0.042
Trypanosoma cruzi succinyl-CoA synthetase alpha subunit, putative 0.0008 0.0031 0.0143
Mycobacterium leprae Conserved hypothetical protein 0.0215 0.2789 0.5852
Onchocerca volvulus 0.0063 0.0769 0.1141
Echinococcus multilocularis thioredoxin glutathione reductase 0.0071 0.0865 0.1516
Brugia malayi 6-phosphofructokinase 0.0101 0.127 0.2162
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0008 0.0032 0.0066
Echinococcus granulosus neural cadherin 0.0028 0.0299 0.0525
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0003
Mycobacterium ulcerans lipoprotein LpqF 0.0362 0.476 0.4755
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Leishmania major tyrosyl or methionyl-tRNA synthetase-like protein 0.0012 0.008 0.0461
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0286 0.0417
Plasmodium vivax thioredoxin reductase, putative 0.007 0.0859 0.5485
Schistosoma mansoni glutamate receptor kainate 0.0143 0.1833 0.3771
Onchocerca volvulus Dual oxidase homolog 0.0218 0.2838 0.4245
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0028 0.0299 0.0436
Schistosoma mansoni tar DNA-binding protein 0.0031 0.034 0.07
Toxoplasma gondii tRNA synthetases class I family protein 0.0015 0.0126 0.0757
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0049 0.0576 0.1186
Mycobacterium leprae Probable lipase LipE 0.0016 0.0138 0.0273
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.016 0.2059 0.4316
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.008 0.0139
Toxoplasma gondii aminopeptidase N, putative 0.0017 0.0152 0.0926
Echinococcus multilocularis neurogenic locus protein delta 0.0028 0.0299 0.0525
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.0213
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0008 0.0032 0.0046
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0009 0.0044 0.0075
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0116 0.1474 0.2128
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0101 0.127 0.1262
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.008 0.0107
Mycobacterium ulcerans arylsulfatase, AslA 0.0014 0.0111 0.0103
Onchocerca volvulus 0.0049 0.0576 0.0851
Echinococcus granulosus peroxidasin 0.0218 0.2838 0.4974
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0012 0.0086 0.0615
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0031 0.0342 0.0703
Mycobacterium tuberculosis Probable esterase LipL 0.0016 0.0138 0.013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.008 0.0127
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0054 0.065 0.0642
Leishmania major hypothetical protein, conserved 0.0012 0.008 0.0461
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0009 0.0044 0.0036
Loa Loa (eye worm) glutamate receptor 0.0358 0.4702 0.6808
Mycobacterium ulcerans succinyl-CoA synthetase subunit alpha 0.0008 0.0031 0.0022
Chlamydia trachomatis glutamine binding protein 0.0083 0.1035 0.2601
Loa Loa (eye worm) hypothetical protein 0.0023 0.0232 0.0329
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0013 0.0092 0.0125
Brugia malayi Calcium binding EGF domain containing protein 0.0028 0.0299 0.0502
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0008 0.0026 0.0017
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.008 0.0164
Brugia malayi Bromodomain containing protein 0.0037 0.0419 0.0707
Brugia malayi Peptidase family M1 containing protein 0.0049 0.0576 0.0976
Leishmania major hypothetical protein, conserved 0.0007 0.0022 0.0083
Loa Loa (eye worm) peptidase family M13 containing protein 0.0023 0.0232 0.0329
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0193
Leishmania major hypothetical protein, conserved 0.0009 0.0037 0.0181
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0032 0.0346 0.0607
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Brugia malayi Bromodomain containing protein 0.0019 0.0171 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Brugia malayi CHD4 protein 0.001 0.0055 0.0085
Schistosoma mansoni 6-phosphofructokinase 0.0101 0.127 0.2613
Mycobacterium ulcerans arylsulfatase AtsD 0.0014 0.0111 0.0103
Mycobacterium leprae Probable succinyl-CoA synthetase (alpha chain) SucD (SCS-alpha) 0.0008 0.0031 0.0047
Echinococcus multilocularis tumor protein p63 0.0115 0.1453 0.2546
Brugia malayi methionyl-tRNA synthetase 0.0012 0.008 0.0128
Brugia malayi TAR-binding protein 0.0031 0.034 0.0573
Loa Loa (eye worm) hypothetical protein 0.0024 0.024 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.016 0.2059 0.2052
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0301 0.0616
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0206 0.2679 0.4695
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0008 0.0032 0.0151
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0206 0.2679 0.4695
Trichomonas vaginalis chromobox protein, putative 0.0008 0.0032 0.0035
Brugia malayi Glycosyl hydrolases family 31 protein 0.0012 0.0086 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Onchocerca volvulus 0.0016 0.0138 0.0195
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0016 0.0134 0.0276
Trichomonas vaginalis methionyl-tRNA synthetase, putative 0.0012 0.008 0.0107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0032 0.0035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.008 0.0164
Brugia malayi CXXC zinc finger family protein 0.0014 0.0109 0.0176
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0083 0.1035 0.1028
Onchocerca volvulus 0.0105 0.1319 0.1965
Echinococcus granulosus protein jagged 2 0.0028 0.0299 0.0525
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.008 0.0139
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0162 0.0987
Loa Loa (eye worm) beta-lactamase 0.0016 0.0138 0.0193
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0016 0.0137 0.0269
Leishmania major alpha glucosidase II subunit, putative 0.0012 0.0086 0.05
Loa Loa (eye worm) succinate-CoA ligase 0.0008 0.0031 0.0037
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0247 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0064 0.0355
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0028 0.0299 0.0616
Mycobacterium ulcerans hypothetical protein 0.0028 0.0301 0.0293
Chlamydia trachomatis recombinase RecA 0.0037 0.0411 0.102
Loa Loa (eye worm) hypothetical protein 0.0024 0.024 0.0339
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.008 0.0139
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit beta 0.0012 0.008 0.0181
Echinococcus granulosus ornithine aminotransferase 0.0008 0.0026 0.0045
Brugia malayi hypothetical protein 0.0063 0.0769 0.1305
Schistosoma mansoni notch 0.0028 0.0299 0.0616
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0049 0.0576 0.0851
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0016 0.0134 0.0276
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Echinococcus multilocularis neutral amino acid transporter A 0.0302 0.3956 0.6933
Brugia malayi glutamate synthase 0.0006 0.0009 0.0006
Brugia malayi phosphofructokinase 0.0101 0.127 0.2161
Echinococcus granulosus ribosomal protein L19 0.0013 0.0092 0.0161
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0006 0.0009 0.0015
Schistosoma mansoni disulfide oxidoreductase 0.0006 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0887 0.1278
Mycobacterium tuberculosis Conserved protein 0.0016 0.0138 0.013
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0009 0.0044 0.023
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0101 0.127 0.8131
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0298 0.0434
Trichomonas vaginalis phosphofructokinase, putative 0.0101 0.127 0.1892
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.008 0.0107
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0116 0.1474 0.2128
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0054 0.065 0.0642
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0031 0.034 0.0485
Entamoeba histolytica hypothetical protein 0.0008 0.0032 0.0186
Entamoeba histolytica hypothetical protein 0.0012 0.008 0.0567
Plasmodium vivax tyrosine--tRNA ligase, putative 0.0015 0.0126 0.0757
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0074 0.0098
Brugia malayi 6-phosphofructokinase 0.0101 0.127 0.2161
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0247 0.0502
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0755 1 1
Schistosoma mansoni laminin gamma-3 chain 0.0028 0.0299 0.0616
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0008 0.0026 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0777 0.1599
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0247 0.0433
Brugia malayi N-terminal motif family protein 0.0081 0.1005 0.1709
Echinococcus multilocularis succinyl coenzyme A synthetase alpha subunit 0.0008 0.0031 0.0054
Onchocerca volvulus Excitatory amino acid transporter homolog 0.0302 0.3956 0.5922
Plasmodium falciparum 60S ribosomal protein L19 0.0013 0.0092 0.0538
Echinococcus granulosus endothelin converting enzyme 1 0.0031 0.0342 0.0599
Loa Loa (eye worm) notch protein 0.0028 0.0299 0.0426
Brugia malayi Glycosyl hydrolases family 31 protein 0.0055 0.066 0.112
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0072 0.0887 0.1826
Loa Loa (eye worm) peptidase family M13 containing protein 0.0023 0.0232 0.0329
Schistosoma mansoni DNA helicase recq5 0.0008 0.0032 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.008 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.008 0.0127
Toxoplasma gondii methionyl-tRNA synthetase 0.0012 0.008 0.0461
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Onchocerca volvulus Slit protein homolog 0.0028 0.0299 0.0436
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.008 0.0107
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0013 0.0092 0.0176
Brugia malayi Glutamate receptor 1 precursor 0.0143 0.1833 0.3123
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0187 0.0268
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0008 0.0032 0.0038
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0049 0.0576 0.0851
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0086 0.0116
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0014 0.0111 0.0103
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Trypanosoma cruzi PAB1-binding protein , putative 0.0009 0.0037 0.0181
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0008 0.0026 0.0053
Schistosoma mansoni chromobox protein 0.005 0.0592 0.1219
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0034 0.0372 0.0544
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.008 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0086 0.05
Schistosoma mansoni 6-phosphofructokinase 0.0101 0.127 0.2613
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Schistosoma mansoni glutamate synthase 0.0006 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0298 0.0424
Schistosoma mansoni 60S ribosomal protein L19 0.0013 0.0092 0.019
Loa Loa (eye worm) blistered cuticle protein 3 0.0218 0.2838 0.4106
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.008 0.0107
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni cellular tumor antigen P53 0.0017 0.0146 0.0301
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0013 0.0092 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0031 0.034 0.07
Brugia malayi RNA binding protein 0.0031 0.034 0.0573
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0032 0.0151
Trypanosoma brucei tyrosyl/methionyl-tRNA synthetase, putative 0.0012 0.008 0.0151
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0247 0.1538
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.008 0.0139
Echinococcus multilocularis neuropeptide s receptor 0.0159 0.2046 0.3586
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0018 0.0161 0.0266
Echinococcus granulosus chromobox protein 2 0.0008 0.0032 0.0056
Toxoplasma gondii phosphofructokinase PFKII 0.0027 0.0286 0.1791
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0436 0.0735
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0032 0.0045
Echinococcus multilocularis inositol monophosphatase 1 0.0018 0.0162 0.0283
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0074 0.0098
Schistosoma mansoni tar DNA-binding protein 0.0031 0.034 0.07
Chlamydia trachomatis neutral amino acid transporter 0.0134 0.171 0.4311
Echinococcus granulosus glutamate receptor subunit protein glur 0.0064 0.0777 0.1362
Mycobacterium ulcerans recombinase A 0.0037 0.0411 0.0403
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0178 0.2298 0.4818
Mycobacterium tuberculosis Putative ferredoxin reductase 0.016 0.2059 0.2052
Loa Loa (eye worm) ATP-citrate synthase 0.0041 0.0476 0.0682
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0015 0.0126 0.0247
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.0302 0.3956 0.814
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0247 0.0502
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0064 0.0083
Schistosoma mansoni intermediate filament proteins 0.0022 0.0219 0.0451
Echinococcus multilocularis lysosomal alpha glucosidase 0.0055 0.066 0.1157
Loa Loa (eye worm) hypothetical protein 0.0024 0.024 0.0339
Mycobacterium tuberculosis Conserved protein TB27.3 0.0028 0.0301 0.0293
Trichomonas vaginalis succinate thiokinase a subunit 0.0008 0.0031 0.0033
Trichomonas vaginalis chromobox protein, putative 0.005 0.0592 0.0876
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Mycobacterium ulcerans beta-lactamase 0.0016 0.0138 0.013
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0032 0.0186
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0017 0.0152 0.0926
Loa Loa (eye worm) glutamate receptor 2 0.0143 0.1833 0.2648
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0074 0.0098
Schistosoma mansoni hypothetical protein 0.0301 0.3942 0.8112
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0054 0.065 0.135
Mycobacterium ulcerans aminopeptidase N PepN 0.0049 0.0576 0.0568
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0013 0.0101 0.0597
Echinococcus granulosus receptor type guanylyl cyclase 0.0063 0.0769 0.1348
Loa Loa (eye worm) hypothetical protein 0.0017 0.0152 0.0213
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0147 0.189 0.3313
Loa Loa (eye worm) heterochromatin protein 1 0.005 0.0592 0.0851
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0193
Echinococcus granulosus Excitatory amino acid transporter 0.0302 0.3956 0.6933
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.008 0.0139
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0362 0.476 1
Toxoplasma gondii thioredoxin reductase 0.007 0.0859 0.5485
Onchocerca volvulus 0.0028 0.0299 0.0436
Loa Loa (eye worm) TATA binding protein associated factor 0.0017 0.0152 0.0213
Echinococcus granulosus glutamate receptor 2 0.0206 0.2679 0.4695
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0017 0.0152 0.0267
Brugia malayi Animal haem peroxidase family protein 0.0218 0.2838 0.4842
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Echinococcus granulosus Excitatory amino acid transporter 0.0302 0.3956 0.6933
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.008 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.008 0.0127
Loa Loa (eye worm) hypothetical protein 0.0006 0.0009 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.003 0.032 0.056
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0064 0.0777 0.1362
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Onchocerca volvulus 0.0028 0.0299 0.0436
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0134 0.171 0.3519
Echinococcus granulosus sodium:dicarboxylate symporter 0.0302 0.3956 0.6933
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.008 0.0127
Schistosoma mansoni cpg binding protein 0.0014 0.0109 0.0223
Loa Loa (eye worm) hypothetical protein 0.0024 0.024 0.0339
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0018 0.0162 0.0153
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0027 0.0286 0.1791
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0305 0.3998 0.7006
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.037 0.4859 1
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0008 0.0026 0.0036
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.008 0.0164
Schistosoma mansoni hypothetical protein 0.0006 0.0009 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0301 0.0439
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0006 0.0009 0.0015
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.0329
Onchocerca volvulus 0.0008 0.0031 0.0033
Schistosoma mansoni cell polarity protein 0.0028 0.0299 0.0616
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0008 0.0025 0.0051
Schistosoma mansoni notch 0.0028 0.0299 0.0616
Schistosoma mansoni notch 0.0028 0.0299 0.0616
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0012 0.008 0.0461
Mycobacterium ulcerans glyoxalase GloA 0.0028 0.0301 0.0293
Plasmodium falciparum ataxin-2 like protein, putative 0.0009 0.0037 0.0181
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0086 0.0116
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0123 0.156 0.2327
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0206 0.2674 0.3868
Entamoeba histolytica phosphofructokinase, putative 0.0101 0.127 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0012 0.0079 0.0139
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0074 0.0098
Schistosoma mansoni gynecophoral canal protein 0.0028 0.0301 0.062
Brugia malayi Muscle positioning protein 4 0.0028 0.0299 0.0502
Loa Loa (eye worm) glutamate receptor 1 0.0143 0.1833 0.2648
Schistosoma mansoni hypothetical protein 0.0038 0.0436 0.0896
Echinococcus multilocularis neurogenic locus notch protein 4 0.0028 0.0299 0.0525
Brugia malayi intermediate filament protein 0.0022 0.0219 0.0366
Brugia malayi Cadherin domain containing protein 0.0028 0.0299 0.0502
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Brugia malayi RNA recognition motif domain containing protein 0.0031 0.034 0.0573
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.0329
Chlamydia trachomatis succinyl-CoA ligase subunit alpha 0.0008 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0116 0.1474 0.2128
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0247 0.0358
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0028 0.0298 0.0434
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0063 0.0769 0.1141
Treponema pallidum exodeoxyribonuclease (exoA) 0.0009 0.0044 0.021
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0247 0.0502
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0064 0.0777 0.1362
Entamoeba histolytica heat shock transcription factor, putative 0.0034 0.0372 0.2878
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Loa Loa (eye worm) hypothetical protein 0.0034 0.0372 0.0531
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0247 0.1538
Echinococcus granulosus neutral amino acid transporter 0.0302 0.3956 0.6933
Loa Loa (eye worm) hypothetical protein 0.0016 0.0133 0.0186
Trypanosoma cruzi aminopeptidase, putative 0.0017 0.0152 0.0926
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0028 0.0301 0.0293
Echinococcus granulosus lamin dm0 0.0022 0.0219 0.0384
Plasmodium falciparum glyoxalase I 0.0123 0.156 1
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0013 0.0092 0.0662
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0014 0.0111 0.0103
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0006 0.0009 0.0015
Echinococcus granulosus fetal alzheimer antigen falz 0.0012 0.0079 0.0139
Onchocerca volvulus 0.0017 0.0146 0.0207
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0178 0.2298 0.2291
Onchocerca volvulus Neurogenic locus notch homolog 0.0028 0.0299 0.0436
Leishmania major succinyl-CoA synthetase alpha subunit, putative 0.0008 0.0031 0.0143
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0016 0.0138 0.013
Brugia malayi Pre-SET motif family protein 0.0444 0.5855 1
Schistosoma mansoni DNA helicase recq1 0.0008 0.0032 0.0065
Echinococcus granulosus intermediate filament protein 0.0022 0.0219 0.0384
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0247 0.1538
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0016 0.0138 0.013
Onchocerca volvulus 0.0016 0.0138 0.0195
Mycobacterium tuberculosis Probable lipase LipE 0.0016 0.0138 0.013
Schistosoma mansoni lamin 0.0022 0.0219 0.0451
Brugia malayi Peptidase family M1 containing protein 0.0105 0.1319 0.2245
Mycobacterium ulcerans lipase LipD 0.0016 0.0138 0.013
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0009 0.0044 0.1227
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.0086 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.008 0.0127
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.016 0.0264
Loa Loa (eye worm) hypothetical protein 0.0032 0.0346 0.0494
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0463 0.0663
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.008 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.008 0.0127
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.008 0.0106
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.016 0.028
Giardia lamblia High cysteine protein 0.0028 0.0299 1
Brugia malayi hypothetical protein 0.0049 0.0576 0.0976
Schistosoma mansoni neprilysin 0.0008 0.0032 0.0066
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0123 0.156 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0016 0.0138 0.013
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.008 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Mycobacterium tuberculosis Probable lipase LipD 0.0016 0.0138 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0008 0.0032 0.0035
Plasmodium vivax heterochromatin protein 1, putative 0.0008 0.0032 0.0151
Leishmania major 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Loa Loa (eye worm) hypothetical protein 0.0032 0.0346 0.0494
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0219 0.031
Echinococcus granulosus metabotropic glutamate receptor 2 0.0305 0.3998 0.7006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0101 0.127 0.2654
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0008 0.0032 0.0151
Loa Loa (eye worm) hypothetical protein 0.0009 0.0037 0.0045
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.016 0.2059 0.2052
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0138 0.0195
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0286 0.0417
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0247 0.0239
Trichomonas vaginalis hypothetical protein 0.0008 0.0032 0.0035
Echinococcus granulosus cpg binding protein 0.0016 0.0131 0.023
Trypanosoma cruzi ISWI complex protein 0.0007 0.0022 0.0083
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Onchocerca volvulus 0.0072 0.0887 0.1317
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0008 0.0032 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Loa Loa (eye worm) hypothetical protein 0.002 0.0186 0.0262
Echinococcus multilocularis nmda type glutamate receptor 0.0063 0.0769 0.1348
Schistosoma mansoni aminopeptidase A (M01 family) 0.0017 0.0152 0.0313
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Onchocerca volvulus 0.0019 0.0175 0.025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.008 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0298 0.0434
Giardia lamblia Hypothetical protein 0.0014 0.0111 0.3536
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0012 0.008 0.0461
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.007 0.0859 0.0851
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0008 0.0026 0.0044
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0049 0.0576 0.3659
Leishmania major ATP-dependent phosphofructokinase 0.0101 0.127 0.8131
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Schistosoma mansoni glutamate synthase 0.0006 0.0009 0.0018
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0016 0.0134 0.0276
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.0302 0.3956 0.3951
Loa Loa (eye worm) RGC/RGC protein kinase 0.0063 0.0769 0.1107
Trypanosoma brucei Aminopeptidase M1, putative 0.0049 0.0576 0.1194
Trichomonas vaginalis ap endonuclease, putative 0.0009 0.0044 0.0053
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0066
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0049 0.0576 0.1194
Schistosoma mansoni glutamate receptor AMPA 0.0143 0.1833 0.3771
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0188 0.027
Schistosoma mansoni zinc finger protein 0.0007 0.0022 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Trypanosoma cruzi DNA repair protein, putative 0.0011 0.0073 0.0415
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0011 0.0073 0.0135
Echinococcus multilocularis protein jagged 1 0.0028 0.0299 0.0525
Schistosoma mansoni chromobox protein 0.0008 0.0032 0.0066
Onchocerca volvulus 0.0218 0.2838 0.4245
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Trypanosoma cruzi ISWI complex protein 0.0007 0.0022 0.0083
Loa Loa (eye worm) CXXC zinc finger family protein 0.0014 0.0109 0.0149
Echinococcus multilocularis chromobox protein 1 0.005 0.0592 0.1038
Schistosoma mansoni inositol monophosphatase 0.0018 0.0162 0.0333
Echinococcus multilocularis beta LACTamase domain containing family member 0.0016 0.0138 0.0243
Loa Loa (eye worm) hypothetical protein 0.0023 0.0232 0.0329
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0032 0.0346 0.2177
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Echinococcus multilocularis neurogenic locus notch protein 0.0028 0.0299 0.0525
Echinococcus granulosus X box binding protein 1 0.0098 0.1227 0.2151
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0247 0.0604
Onchocerca volvulus 0.0218 0.2838 0.4245
Schistosoma mansoni notch 0.0028 0.0299 0.0616
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0017 0.0152 0.0216
Trichomonas vaginalis esterase, putative 0.0016 0.0138 0.0195
Echinococcus granulosus glutamate NMDA receptor subunit 0.0143 0.1833 0.3212
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0286 0.0417
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0082 0.013
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0009 0.0044 0.0283
Mycobacterium ulcerans 6-phosphofructokinase 0.0101 0.127 0.1262
Brugia malayi SET domain containing protein 0.0011 0.0067 0.0106
Schistosoma mansoni lamin 0.0022 0.0219 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Mycobacterium tuberculosis Conserved protein 0.0016 0.0138 0.013
Plasmodium vivax ornithine aminotransferase, putative 0.0008 0.0026 0.0111
Schistosoma mansoni hypothetical protein 0.0018 0.016 0.0329
Echinococcus granulosus Aminotransferase class III 0.0008 0.0026 0.0045
Schistosoma mansoni hypothetical protein 0.0028 0.0299 0.0616
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Schistosoma mansoni tyrosine kinase 0.0063 0.0769 0.1582
Trypanosoma cruzi DNA repair protein, putative 0.0011 0.0073 0.0415
Brugia malayi Guanylyl cyclase protein 23 0.0063 0.0769 0.1305
Loa Loa (eye worm) hypothetical protein 0.0017 0.0146 0.0204
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0008 0.0026 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0032 0.0151
Schistosoma mansoni septate junction protein 0.0028 0.0299 0.0616
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0072 0.0887 0.1555
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0018 0.0162 0.023
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0006 0.0009 0.0015
Echinococcus multilocularis glutamate receptor 2 0.0142 0.1824 0.3197
Plasmodium falciparum glutathione reductase 0.007 0.0859 0.5485
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0295 0.3856 0.6583
Loa Loa (eye worm) hypothetical protein 0.0123 0.156 0.2253
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.0566 0.7477 0.7475
Loa Loa (eye worm) hypothetical protein 0.0523 0.6905 1
Treponema pallidum recombinase A 0.0037 0.0411 0.2366
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0286 0.0417
Loa Loa (eye worm) hypothetical protein 0.0021 0.0209 0.0296
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0138 0.0195
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0247 0.0239
Brugia malayi Peptidase family M13 containing protein 0.0031 0.0342 0.0575
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0027 0.0286 0.9559
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0348 0.0717
Brugia malayi Calcium binding EGF domain containing protein 0.0028 0.0299 0.0502
Echinococcus granulosus inositol monophosphatase 1 0.0018 0.0162 0.0283
Brugia malayi Valyl-tRNA synthetase 0.0008 0.0032 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0032 0.0346 0.0713
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.008 0.0127
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0038
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.008 0.0139
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0064 0.0777 0.1362
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0016 0.0134 0.0276
Onchocerca volvulus Poor gastrulation protein homolog 0.0053 0.0627 0.0928
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Schistosoma mansoni glutamate receptor NMDA 0.0206 0.2679 0.5513
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni alpha glucosidase 0.0012 0.0086 0.0177
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0015 0.0126 0.0176
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0008 0.0032 0.0148
Mycobacterium ulcerans sulfatase 0.0014 0.0111 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0032 0.0035
Toxoplasma gondii glyoxalase I, putative 0.0123 0.156 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.008 0.0107
Mycobacterium leprae probable zinc metalloprotease 0.0031 0.0342 0.0701
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.008 0.0127
Brugia malayi Pre-SET motif family protein 0.0064 0.0777 0.1319
Echinococcus granulosus GPCR family 3 C terminal 0.0053 0.0627 0.1099
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.0032 0.0151
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0008 0.0026 0.0017
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0009 0.0044 0.009
Mycobacterium ulcerans hypothetical protein 0.0028 0.0301 0.0293
Mycobacterium tuberculosis Probable dehydrogenase 0.016 0.2059 0.2052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0193
Treponema pallidum glutamate/aspartate transporter 0.0134 0.171 1
Toxoplasma gondii ribosomal protein RPL19 0.0013 0.0092 0.0538
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0123 0.156 1
Loa Loa (eye worm) RecQ helicase 0.002 0.0187 0.0263
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0206 0.2679 0.4695
Trichomonas vaginalis penicillin-binding protein, putative 0.0016 0.0138 0.0195
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0018 0.0162 0.0388
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.008 0.0461
Schistosoma mansoni hypothetical protein 0.0007 0.0022 0.0044
Echinococcus granulosus Chromo domain 0.0008 0.0032 0.0056
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Echinococcus multilocularis excitatory amino acid transporter 2 0.0302 0.3956 0.6933
Echinococcus multilocularis fat cadherin tumor suppressor 0.0028 0.0299 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Schistosoma mansoni tyrosyl-tRNA synthetase 0.0027 0.0284 0.0584
Echinococcus multilocularis nmda type glutamate receptor 0.0147 0.189 0.3313
Brugia malayi hypothetical protein 0.0009 0.0037 0.0053
Echinococcus multilocularis ribosomal protein L19 0.0013 0.0092 0.0161
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0673 0.0968
Mycobacterium ulcerans zinc metalloprotease 0.0031 0.0342 0.0333
Echinococcus multilocularis Excitatory amino acid transporter 0.0302 0.3956 0.6933
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.008 0.0164
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0008 0.0032 0.0066
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0027 0.0286 0.1633
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Trichomonas vaginalis chromobox protein, putative 0.003 0.0327 0.0477
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Brugia malayi Metabotropic glutamate receptor precursor. 0.0358 0.4702 0.803
Brugia malayi Peroxidasin 0.0218 0.2838 0.4842
Echinococcus multilocularis endothelin converting enzyme 1 0.0031 0.0342 0.0599
Trichomonas vaginalis phosphofructokinase, putative 0.0101 0.127 0.1892
Brugia malayi PHD-finger family protein 0.0013 0.0094 0.0152
Echinococcus multilocularis bloom syndrome protein 0.002 0.0187 0.0328
Echinococcus multilocularis 6 phosphofructokinase 0.0101 0.127 0.2225
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0017 0.0152 0.0926
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0074 0.0098
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0247 0.1538
Onchocerca volvulus Peroxidasin homolog 0.0218 0.2838 0.4245
Brugia malayi 60S ribosomal protein L19 0.0013 0.0092 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0074 0.0098
Mycobacterium ulcerans arylsulfatase AtsD 0.0014 0.0111 0.0103
Onchocerca volvulus Chorion peroxidase homolog 0.0218 0.2838 0.4245
Schistosoma mansoni tar DNA-binding protein 0.0031 0.034 0.07
Brugia malayi Angiotensin-converting enzyme family protein 0.0206 0.2674 0.4562
Mycobacterium tuberculosis Possible hydrolase 0.0014 0.0111 0.0103
Mycobacterium ulcerans aminopeptidase N PepN 0.0017 0.0152 0.0144
Echinococcus granulosus protein jagged 2 0.0028 0.0299 0.0525
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Schistosoma mansoni protein kinase 0.0063 0.0769 0.1582
Loa Loa (eye worm) hypothetical protein 0.0018 0.016 0.0224
Toxoplasma gondii histone lysine methyltransferase SET1 0.003 0.0322 0.2017
Mycobacterium ulcerans hypothetical protein 0.0028 0.0301 0.0293
Loa Loa (eye worm) hypothetical protein 0.0031 0.0342 0.0487
Mycobacterium tuberculosis Probable reductase 0.016 0.2059 0.2052
Echinococcus granulosus lysosomal alpha glucosidase 0.0055 0.066 0.1157
Brugia malayi chromobox protein homolog 3 0.0028 0.0298 0.05
Schistosoma mansoni notch 0.0028 0.0299 0.0616
Echinococcus multilocularis glutamate receptor 2 0.0143 0.1833 0.3212
Schistosoma mansoni glutamate receptor AMPA 0.0143 0.1833 0.3771
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0031 0.0342 0.0575
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0014 0.0111 0.0154
Loa Loa (eye worm) hypothetical protein 0.0022 0.0214 0.0302
Onchocerca volvulus Peroxidasin homolog 0.0218 0.2838 0.4245
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0008 0.0032 0.0151
Plasmodium vivax SET domain protein, putative 0.0064 0.0777 0.4954
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0024 0.0247 0.0604
Loa Loa (eye worm) hypothetical protein 0.0063 0.0769 0.1107
Trichomonas vaginalis ap endonuclease, putative 0.0009 0.0044 0.0053
Schistosoma mansoni methyl-cpg binding protein mbd 0.0008 0.0033 0.0068
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0006 0.0009 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0138 0.0273
Trichomonas vaginalis maltase-glucoamylase, putative 0.0012 0.0086 0.0116
Echinococcus multilocularis neural cadherin 0.0028 0.0299 0.0525
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.008 0.0139
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0037 0.0411 0.102
Echinococcus granulosus protein jagged 1 0.0028 0.0299 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.008 0.0127
Echinococcus multilocularis muscleblind protein 0.0051 0.0599 0.105
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Plasmodium vivax glyoxalase I, putative 0.0123 0.156 1
Echinococcus granulosus fibropellin Ia 0.0028 0.0299 0.0525
Loa Loa (eye worm) hypothetical protein 0.0031 0.0342 0.0487
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0053 0.0627 0.1063
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0055 0.066 0.0949
Trypanosoma cruzi Aminopeptidase M1, putative 0.0049 0.0576 0.3659
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0247 0.1538
Echinococcus granulosus lamin 0.0022 0.0219 0.0384
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0064 0.0777 0.1362
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0017 0.0152 0.0267
Brugia malayi metabotropic glutamate receptor type 2 0.0191 0.2477 0.4225
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0099 0.0584
Onchocerca volvulus 0.0028 0.0299 0.0436
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0018 0.0162 0.0987
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.003 0.032 0.056
Plasmodium falciparum tyrosine--tRNA ligase 0.0015 0.0126 0.0757
Toxoplasma gondii LsmAD domain-containing protein 0.0009 0.0037 0.0181
Loa Loa (eye worm) hypothetical protein 0.0218 0.2838 0.4106
Onchocerca volvulus Peroxidase homolog 0.0218 0.2838 0.4245
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.008 0.0164
Echinococcus multilocularis peroxidasin 0.0218 0.2838 0.4974
Echinococcus granulosus neutral alpha glucosidase AB 0.0012 0.0086 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.008 0.0107
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0134 0.171 0.3519
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0206 0.2679 0.4695
Echinococcus multilocularis ornithine aminotransferase 0.0008 0.0026 0.0045
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0017 0.0152 0.0926
Echinococcus granulosus tyrosine kinase 0.0063 0.0769 0.1348
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0037 0.0411 0.0847
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0008 0.0032 0.0148
Echinococcus multilocularis musashi 0.0022 0.0219 0.0384
Echinococcus granulosus protein jagged 1 0.0028 0.0299 0.0525
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0673 0.1141
Entamoeba histolytica hypothetical protein 0.0008 0.0032 0.0186
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0013 0.0092 0.0538
Brugia malayi EGF-like domain containing protein 0.0028 0.0299 0.0502
Entamoeba histolytica hypothetical protein 0.0063 0.0769 0.6028
Trypanosoma cruzi extracellular receptor, putative 0.0063 0.0769 0.4902
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0018 0.0162 0.0987
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0049 0.0576 0.3659
Echinococcus multilocularis Excitatory amino acid transporter 0.0302 0.3956 0.6933
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0064 0.0355
Loa Loa (eye worm) transcription factor SMAD2 0.0041 0.0463 0.0663
Echinococcus granulosus geminin 0.0301 0.3942 0.6909
Plasmodium vivax ataxin-2 like protein, putative 0.0009 0.0037 0.0181
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Schistosoma mansoni cpg binding protein 0.0016 0.0131 0.0271
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0009 0.0044 0.023
Giardia lamblia Ribosomal protein L19 0.0013 0.0092 0.2872
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0014 0.0111 0.0154
Echinococcus granulosus neutral amino acid transporter A 0.0302 0.3956 0.6933
Brugia malayi glutathione reductase 0.007 0.0859 0.146
Loa Loa (eye worm) hypothetical protein 0.0053 0.0627 0.0901
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0008 0.0026 0.0017
Plasmodium falciparum tRNA import protein tRIP 0.0012 0.008 0.0461
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0008 0.0026 0.0111
Brugia malayi hypothetical protein 0.0093 0.1162 0.1978
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0009 0.0044 0.0078
Onchocerca volvulus 0.0028 0.0299 0.0436
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Plasmodium falciparum ornithine aminotransferase 0.0008 0.0026 0.0111
Mycobacterium tuberculosis Probable succinyl-CoA synthetase (alpha chain) SucD (SCS-alpha) 0.0008 0.0031 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.0027 0.0286 0.0417
Chlamydia trachomatis phenylalanine--tRNA ligase subunit beta 0.0012 0.008 0.0181
Echinococcus granulosus bloom syndrome protein 0.002 0.0187 0.0328
Echinococcus multilocularis notch 0.0028 0.0299 0.0525
Loa Loa (eye worm) inositol-1 0.0018 0.0162 0.0227
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0008 0.0025 0.0051
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.008 0.0164
Trypanosoma brucei succinyl-CoA synthetase alpha subunit, putative 0.0008 0.0031 0.0047
Leishmania major hypothetical protein 0.0012 0.008 0.0461
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0032 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Loa Loa (eye worm) hypothetical protein 0.0028 0.0299 0.0426
Brugia malayi HSF-type DNA-binding domain containing protein 0.0034 0.0372 0.0626
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0012 0.008 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Loa Loa (eye worm) peptidase family M1 containing protein 0.0073 0.0895 0.1289
Onchocerca volvulus 0.0506 0.6674 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0063 0.0769 0.1348
Onchocerca volvulus 0.0022 0.0219 0.0316
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0008 0.0026 0.0017
Plasmodium falciparum succinyl-CoA synthetase alpha subunit, putative 0.0008 0.0031 0.0143
Echinococcus granulosus neuropeptide s receptor 0.0159 0.2046 0.3586
Loa Loa (eye worm) RNA binding protein 0.0031 0.034 0.0485
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.008 0.0106
Trypanosoma brucei trypanothione reductase 0.007 0.0859 0.179
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Brugia malayi peptidase family M13 containing protein 0.0008 0.0025 0.0033
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Echinococcus granulosus ribosomal protein L19 0.0013 0.0092 0.0161
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.0302 0.3956 1
Schistosoma mansoni zinc finger protein 0.001 0.006 0.0123
Schistosoma mansoni hypothetical protein 0.0019 0.0175 0.0361
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0049 0.0576 0.101
Brugia malayi nuclear hormone receptor 0.0012 0.008 0.0127
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.016 0.028
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.001 0.0055 0.0097
Loa Loa (eye worm) hypothetical protein 0.0012 0.008 0.0107
Echinococcus granulosus thioredoxin glutathione reductase 0.0071 0.0865 0.1516
Plasmodium falciparum thioredoxin reductase 0.007 0.0859 0.5485
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0247 0.8205
Loa Loa (eye worm) excitatory amino acid transporter 0.0302 0.3956 0.5726
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Trichomonas vaginalis phosphofructokinase, putative 0.0101 0.127 0.1892
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0247 0.1538
Brugia malayi lactoylglutathione lyase 0.0123 0.156 0.2657
Brugia malayi Inositol-1 0.0018 0.0162 0.0267
Trichomonas vaginalis penicillin-binding protein, putative 0.0016 0.0138 0.0195
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0054 0.065 0.0962
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0006 0.0009 0.0015
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0206 0.2679 0.4695
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0008 0.0032 0.0151
Echinococcus granulosus tar DNA binding protein 0.0031 0.034 0.0597
Onchocerca volvulus Peroxidase homolog 0.0218 0.2838 0.4245
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.008 0.0127
Echinococcus granulosus tyrosyl tRNA synthetase 0.0027 0.0284 0.0497
Schistosoma mansoni glutamate receptor kainate 0.0143 0.1833 0.3771
Loa Loa (eye worm) hypothetical protein 0.0051 0.0599 0.086
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0008 0.0032 0.0066
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0014 0.0111 0.0154
Echinococcus multilocularis slit 2 protein 0.0028 0.0299 0.0525
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0006 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.008
Brugia malayi GCC2 and GCC3 family protein 0.0028 0.0299 0.0502
Wolbachia endosymbiont of Brugia malayi succinyl-CoA synthetase, alpha subunit 0.0008 0.0031 0.0056
Giardia lamblia Methionyl-tRNA synthetase 0.0012 0.008 0.2462
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0017 0.0155 0.0272
Echinococcus granulosus histone lysine methyltransferase setb 0.0072 0.0887 0.1555
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0131 0.027
Loa Loa (eye worm) hypothetical protein 0.0056 0.0673 0.0968
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0111 0.0154
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0012 0.0086 0.05
Echinococcus multilocularis ribosomal protein L19 0.0013 0.0092 0.0161
Onchocerca volvulus 0.0032 0.0349 0.0511
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0083 0.1035 0.6035
Echinococcus multilocularis Chromobox protein 3 0.0008 0.0032 0.0056
Echinococcus granulosus methyl CpG binding domain protein 2 0.0008 0.0033 0.0058
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0017 0.0155 0.0943
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0101 0.127 0.7411
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0247 0.0239
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.008 0.0127
Mycobacterium tuberculosis Probable oxidoreductase 0.0178 0.2298 0.2291
Mycobacterium ulcerans hypothetical protein 0.0016 0.0138 0.013
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0143 0.1833 0.3212
Loa Loa (eye worm) TAR-binding protein 0.0031 0.034 0.0485
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit beta 0.0012 0.008 0.0072

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

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