Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear hormone receptor | 0.0235 | 0.8778 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.7687 | 0.8757 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0235 | 0.8778 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0049 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.