Detailed information for compound 808717

Basic information

Technical information
  • TDR Targets ID: 808717
  • Name: 4-methoxy-N-(4-nitrophenyl)benzenesulfonamide
  • MW: 308.31 | Formula: C13H12N2O5S
  • H donors: 1 H acceptors: 4 LogP: 2.25 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)[N+](=O)[O-]
  • InChi: 1S/C13H12N2O5S/c1-20-12-6-8-13(9-7-12)21(18,19)14-10-2-4-11(5-3-10)15(16)17/h2-9,14H,1H3
  • InChiKey: SAOGDFMIKZNWCX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • STK042522
  • 4-Methoxy-N-(4-nitro-phenyl)-benzenesulfonamide
  • BAS 00625895
  • ZINC03833369
  • EU-0039853
  • BIM-0011616.P001
  • CBMicro_011804

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus carboxylesterase 5A 0.0013 0.0043 0.0041
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0031 0.0217 0.8089
Brugia malayi prostaglandin transporter 0.0023 0.0142 0.0141
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.0165 0.0017
Echinococcus multilocularis metabotropic glutamate receptor 5 0.068 0.6557 0.6557
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0037 0.0318
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0543 0.0542
Onchocerca volvulus 0.0023 0.0142 0.0141
Schistosoma mansoni transcription factor LCR-F1 0.003 0.0209 0.0208
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0272 0.0272
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0082 0.2585
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.001 0.0011 0.0009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0011 0.0023 0.0099
Schistosoma mansoni survival motor neuron protein 0.0016 0.007 0.0068
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0148 0.1659
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0148 0.1659
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0115 0.5136
Echinococcus granulosus metabotropic glutamate receptor 5 0.068 0.6557 0.6557
Loa Loa (eye worm) acetylcholinesterase 1 0.0013 0.0043 0.0043
Echinococcus granulosus heat shock protein 0.0011 0.0019 0.0018
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0023 0.0142 0.0142
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0009 0.0002 0.0002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0031 0.0217 0.0215
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.001 0.0011 0.0009
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.0165 0.2808
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0052 0.0422 0.0421
Brugia malayi Cytochrome P450 family protein 0.0021 0.0117 0.0115
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0442 0.4227 0.4213
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0091 0.0803 0.0802
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0168 0.1554 0.1427
Brugia malayi metabotropic GABA-B receptor subtype 2 0.009 0.0791 0.0789
Trichomonas vaginalis glucosaminephosphotransferase, putative 0.0019 0.0096 0.0988
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.007
Loa Loa (eye worm) glutaminase 2 0.009 0.0794 0.0794
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0024 0.0148 0.5268
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0564 0.1285
Schistosoma mansoni tar DNA-binding protein 0.0021 0.0119 0.0117
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0052 0.0422 0.0422
Schistosoma mansoni tyrosine kinase 0.0052 0.0422 0.0421
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0052 0.0422 0.0421
Brugia malayi jmjC domain containing protein 0.0017 0.0082 0.0081
Brugia malayi methionyl-tRNA synthetase 0.0024 0.0148 0.0146
Schistosoma mansoni hypothetical protein 0.009 0.0791 0.0789
Echinococcus granulosus neutral amino acid transporter A 0.1033 1 1
Toxoplasma gondii protease inhibitor PI2 0.0016 0.007 0.1105
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0564 0.0562
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0564 0.1285
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0165 0.7509
Leishmania major hypothetical protein, conserved 0.0021 0.0121 0.1872
Loa Loa (eye worm) hypothetical protein 0.0142 0.1298 0.1298
Loa Loa (eye worm) hypothetical protein 0.0078 0.0675 0.0675
Brugia malayi Metabotropic glutamate receptor precursor. 0.0553 0.5311 0.531
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0023 0.0164
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0016 0.007 0.1105
Schistosoma mansoni threonine dehydratase/deaminase 0.005 0.0403 0.0402
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0031 0.0217 0.4898
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0082 0.1324
Trypanosoma brucei tyrosyl/methionyl-tRNA synthetase, putative 0.0024 0.0148 0.5268
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0031 0.0217 0.2548
Plasmodium falciparum ataxin-2 like protein, putative 0.0021 0.0121 0.543
Onchocerca volvulus Putative organic anion transporter 0.0023 0.0142 0.0141
Brugia malayi Carboxylesterase family protein 0.0013 0.0043 0.0041
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0016 0.007 0.0069
Echinococcus multilocularis UDP N acetylglucosamine dolichyl phosphate 0.0019 0.0096 0.0094
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0026 0.0165 0.0142
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0011 0.0023 0.0164
Trypanosoma cruzi MFS transporter, putative 0.0023 0.0142 0.3055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0272 0.027
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0082 0.0081
Trypanosoma cruzi tyrosyl-tRNA synthetase, putative 0.0031 0.0216 0.4874
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0031 0.0217 0.0215
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0422 0.0422
Echinococcus multilocularis agrin 0.0016 0.007 0.0069
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0052 0.0422 0.0421
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0052 0.0422 0.0421
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0037 0.0223
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0422 0.0422
Trichomonas vaginalis rotamase, putative 0.0036 0.0263 0.315
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0038 0.0289 0.0288
Brugia malayi Pre-SET motif family protein 0.001 0.0011 0.0009
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0016 0.007 0.0069
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0543 0.0542
Brugia malayi jmjC domain containing protein 0.0017 0.0082 0.0081
Schistosoma mansoni organic anion transporter 0.0023 0.0142 0.0141
Onchocerca volvulus 0.0023 0.0142 0.0141
Loa Loa (eye worm) RGC/RGC protein kinase 0.0052 0.0422 0.0422
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0016 0.007 0.007
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0016 0.007 0.0068
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0082 0.0081
Echinococcus granulosus tar DNA binding protein 0.0021 0.0119 0.0117
Leishmania major cytochrome p450-like protein 0.0021 0.0117 0.1793
Echinococcus multilocularis excitatory amino acid transporter 2 0.1033 1 1
Entamoeba histolytica hypothetical protein 0.0052 0.0422 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0031 0.0217 0.4898
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.1033 1 1
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0019 0.0096 0.0094
Onchocerca volvulus 0.0016 0.007 0.0069
Entamoeba histolytica hypothetical protein 0.003 0.0209 0.4717
Loa Loa (eye worm) hypothetical protein 0.0019 0.0097 0.0097
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0458 0.4385 0.4384
Trypanosoma cruzi serine-threonine dehydratase, putative 0.005 0.0403 0.9533
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0263 0.4482
Trichomonas vaginalis threonine dehydratase/deaminase, putative 0.005 0.0403 0.4959
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.003 0.0209 0.0208
Trypanosoma brucei UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0019 0.0096 0.3137
Mycobacterium ulcerans glutaminase 0.009 0.0794 0.1833
Plasmodium vivax N-acetylglucosamine-1-phosphate transferase, putative 0.0019 0.0096 0.4152
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0038 0.0289 0.0288
Entamoeba histolytica hypothetical protein 0.003 0.0209 0.4717
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0026 0.0165 0.0336
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0564 0.1285
Echinococcus multilocularis tyrosine kinase 0.0052 0.0422 0.0421
Brugia malayi cytochrome P450 0.0011 0.0023 0.0022
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.1033 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.001 0.0011 0.0009
Echinococcus granulosus neutral amino acid transporter 0.1033 1 1
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0031 0.0216 0.8049
Onchocerca volvulus 0.0023 0.0142 0.0141
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0082 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0021 0.0119 0.0117
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0082 0.1565
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0052 0.0422 0.0421
Plasmodium vivax JmjC domain containing protein 0.0017 0.0082 0.3494
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0016 0.007 0.0068
Brugia malayi sodium-independent organic anion transporter family protein 0.0023 0.0142 0.0141
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0165 0.7532
Mycobacterium leprae Probable threonine dehydratase IlvA 0.005 0.0403 0.0904
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0052 0.0422 0.0421
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0052 0.0422 0.0421
Schistosoma mansoni protein kinase 0.0052 0.0422 0.0421
Entamoeba histolytica threonine dehydratase, putative 0.005 0.0403 0.9533
Onchocerca volvulus 0.0023 0.0142 0.0141
Echinococcus granulosus Excitatory amino acid transporter 0.1033 1 1
Trichomonas vaginalis rotamase, putative 0.0037 0.0272 0.3258
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0009 0.0007 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0082 0.0081
Brugia malayi Carboxylesterase family protein 0.0013 0.0043 0.0041
Echinococcus granulosus Solute carrier organic anion transporter family 0.0023 0.0142 0.0141
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0082 0.1565
Echinococcus granulosus acetylcholinesterase 0.0013 0.0043 0.0041
Echinococcus multilocularis survival motor neuron protein 1 0.0078 0.0675 0.0674
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0543 0.0542
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0463 0.4435 0.4434
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, beta chain PheT 0.0024 0.0148 0.0125
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0037 0.0429
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Onchocerca volvulus 0.0078 0.0676 0.0675
Onchocerca volvulus Poor gastrulation protein homolog 0.009 0.0791 0.0789
Brugia malayi hypothetical protein 0.0023 0.0142 0.0141
Brugia malayi Pyridoxal-phosphate dependent enzyme family protein 0.005 0.0403 0.0402
Echinococcus multilocularis neutral amino acid transporter A 0.1033 1 1
Echinococcus multilocularis tyrosyl tRNA synthetase 0.0055 0.0449 0.0447
Entamoeba histolytica hypothetical protein 0.003 0.0209 0.4717
Brugia malayi Receptor family ligand binding region containing protein 0.0142 0.1298 0.1297
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0082 0.0081
Echinococcus granulosus neutral amino acid transporter A 0.1033 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.003 0.0209 0.0208
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0023 0.0073
Brugia malayi Guanylyl cyclase protein 23 0.0052 0.0422 0.0421
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0019 0.0096 0.0094
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0082 0.1324
Echinococcus multilocularis glutamate receptor 2 0.0052 0.0422 0.0421
Echinococcus granulosus follistatin 0.0016 0.007 0.0069
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0458 0.4385 0.4384
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0052 0.0422 0.0421
Schistosoma mansoni DNA helicase recq1 0.001 0.0009 0.0007
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.009 0.0791 0.0789
Loa Loa (eye worm) hypothetical protein 0.0017 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0031 0.0217 0.2548
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0038 0.0289 0.0288
Brugia malayi hypothetical protein 0.0052 0.0422 0.0421
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0023 0.0142 0.0141
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0024 0.0148 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0148 0.319
Schistosoma mansoni hypothetical protein 0.0011 0.0023 0.0022
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0442 0.4227 0.4213
Echinococcus multilocularis aminoacyl tRNA synthase complex interacting 0.0024 0.0148 0.0146
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0543 0.0542
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0043 0.0041
Echinococcus multilocularis heat shock protein 0.0011 0.0019 0.0018
Mycobacterium ulcerans threonine dehydratase 0.005 0.0403 0.0904
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0117 0.0117
Echinococcus granulosus agrin 0.0016 0.007 0.0069
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Echinococcus granulosus receptor type guanylyl cyclase 0.0052 0.0422 0.0421
Onchocerca volvulus 0.0023 0.0142 0.0141
Trichomonas vaginalis methionyl-tRNA synthetase, putative 0.0024 0.0148 0.1659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0011 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0082 0.0082
Echinococcus multilocularis nmda type glutamate receptor 0.0052 0.0422 0.0421
Brugia malayi hypothetical protein 0.0014 0.0048 0.0047
Toxoplasma gondii heat shock protein HSP90 0.0011 0.0019 0.0187
Echinococcus granulosus nmda type glutamate receptor 0.0052 0.0422 0.0421
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0026 0.0165 0.004
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0165 0.5957
Toxoplasma gondii transporter, major facilitator family protein 0.0023 0.0142 0.2406
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0543 0.0542
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0564 0.0541
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0543 0.0542
Trypanosoma cruzi extracellular receptor, putative 0.0052 0.0422 1
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0564 0.0562
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0082 0.0081
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0038 0.0289 0.0289
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0031 0.0217 0.0215
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0069 0.0584 0.0584
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit beta 0.0024 0.0148 0.0296
Plasmodium vivax tyrosine--tRNA ligase, putative 0.0031 0.0216 1
Onchocerca volvulus 0.0016 0.007 0.0068
Trypanosoma cruzi PAB1-binding protein , putative 0.0021 0.0121 0.2528
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.0011
Echinococcus granulosus heat shock protein 90 0.0011 0.0019 0.0018
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0023 0.0142 0.0141
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0011 0.0009
Echinococcus multilocularis expressed protein 0.0016 0.007 0.0069
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0095 0.0093
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0007
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0023 0.0142 0.0141
Echinococcus granulosus atrial natriuretic peptide receptor 0.0052 0.0422 0.0421
Mycobacterium leprae Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0442 0.4227 1
Brugia malayi secreted modular calcium-binding protein 1 0.0016 0.007 0.0069
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0069 0.2839
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0263 1
Echinococcus granulosus GPCR family 3 C terminal 0.009 0.0791 0.0789
Loa Loa (eye worm) excitatory amino acid transporter 0.1033 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.007
Echinococcus multilocularis L aminoadipate semialdehyde 0.0091 0.0803 0.0802
Toxoplasma gondii tRNA synthetases class I family protein 0.0031 0.0216 0.3728
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.001 0.0011 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0543 0.0543
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0037 0.0429
Leishmania major hypothetical protein, conserved 0.0024 0.0148 0.2361
Giardia lamblia Methionyl-tRNA synthetase 0.0024 0.0148 0.3522
Echinococcus granulosus glutamate receptor 2 0.0052 0.0422 0.0421
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0024 0.0148 0.319
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0011 0.0023 0.0099
Giardia lamblia Threonine dehydratase lateral transfer candidate 0.005 0.0403 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0458 0.4385 0.4384
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit beta 0.0024 0.0148 0.0125
Echinococcus granulosus tyrosyl tRNA synthetase 0.0055 0.0449 0.0447
Toxoplasma gondii cytochrome p450 superfamily protein 0.0011 0.0023 0.026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0038 0.0289 0.0288
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.1033 1 1
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0082 0.0081
Schistosoma mansoni hypothetical protein 0.0009 0.0007 0.0006
Echinococcus multilocularis 0.0011 0.0023 0.0022
Echinococcus multilocularis excitatory amino acid transporter 3 0.1033 1 1
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.1033 1 1
Schistosoma mansoni methionyl-tRNA synthetase 0.0024 0.0148 0.0146
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0009 0.0009
Entamoeba histolytica threonine dehydratase, putative 0.005 0.0403 0.9533
Echinococcus granulosus survival motor neuron protein 1 0.0078 0.0675 0.0674
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0117 0.4001
Echinococcus granulosus UDP N acetylglucosamine dolichyl phosphate 0.0019 0.0096 0.0094
Loa Loa (eye worm) hypothetical protein 0.0091 0.0803 0.0803
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0117 0.0117
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 0.0168 0.1554 0.3318
Brugia malayi heat shock protein 90 0.0011 0.0019 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0021 0.0121 0.4176
Schistosoma mansoni heat shock protein 0.0011 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0082 0.0081
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0009 0.0007
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0564 0.0562
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0082 0.0081
Plasmodium falciparum tRNA import protein tRIP 0.0024 0.0148 0.6719
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0442 0.4227 1
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0628 0.605 0.6049
Echinococcus multilocularis ubiquitin specific protease 41 0.0031 0.0217 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0148 0.1659
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0031 0.0217 0.5266
Echinococcus multilocularis carboxylesterase 5A 0.0013 0.0043 0.0041
Echinococcus granulosus excitatory amino acid transporter 3 0.1033 1 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0031 0.0217 0.3626
Trichomonas vaginalis threonine dehydratase/deaminase, putative 0.005 0.0403 0.4959
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0031 0.0217 0.0215
Echinococcus multilocularis glutamate receptor 2 0.0052 0.0422 0.0421
Entamoeba histolytica UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0019 0.0096 0.19
Plasmodium vivax ataxin-2 like protein, putative 0.0021 0.0121 0.5388
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0016 0.007 0.1105
Echinococcus granulosus tyrosine kinase 0.0052 0.0422 0.0421
Leishmania major hypothetical protein 0.0024 0.0148 0.2361
Leishmania major cytochrome p450-like protein 0.0011 0.0023 0.0073
Onchocerca volvulus Excitatory amino acid transporter homolog 0.1033 1 1
Echinococcus granulosus acetylcholinesterase 0.0013 0.0043 0.0041
Trypanosoma cruzi serine-threonine dehydratase, putative 0.005 0.0403 0.9533
Schistosoma mansoni tyrosyl-tRNA synthetase 0.0055 0.0449 0.0447
Schistosoma mansoni endoplasmin 0.0011 0.0019 0.0018
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0263 0.6055
Echinococcus granulosus Excitatory amino acid transporter 0.1033 1 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0016 0.007 0.1105
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0052 0.0422 0.0421
Loa Loa (eye worm) hypothetical protein 0.0047 0.0376 0.0376
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0021 0.0121 0.2528
Trichomonas vaginalis glutaminase, putative 0.009 0.0794 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0009 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0096
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0082 0.0081
Brugia malayi RNA binding protein 0.0021 0.0119 0.0117
Echinococcus granulosus excitatory amino acid transporter 2 0.1033 1 1
Echinococcus multilocularis neutral amino acid transporter A 0.1033 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0564 1
Chlamydia trachomatis glutamate symporter 0.1033 1 1
Schistosoma mansoni endoplasmin 0.0011 0.0019 0.0018
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0052 0.0422 0.0421
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0121
Loa Loa (eye worm) glutamate receptor 0.0553 0.5311 0.5311
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0011 0.0023 0.0099
Treponema pallidum glutamate transporter 0.0458 0.4385 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0011 0.0023 0.0099
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0117 0.0223
Mycobacterium ulcerans undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe 0.0019 0.0096 0.0173
Giardia lamblia Heat shock protein HSP 90-alpha 0.0011 0.0019 0.0264
Loa Loa (eye worm) TAR-binding protein 0.0021 0.0119 0.0119
Leishmania major cytochrome p450-like protein 0.0011 0.0023 0.0073
Brugia malayi hypothetical protein 0.0023 0.0142 0.0141
Brugia malayi jmjC domain containing protein 0.0064 0.0543 0.0542
Onchocerca volvulus 0.001 0.0011 0.0009
Schistosoma mansoni follistatin 0.0016 0.007 0.0069
Plasmodium falciparum UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0019 0.0096 0.4205
Echinococcus multilocularis tar DNA binding protein 0.0021 0.0119 0.0117
Schistosoma mansoni heat shock protein 0.0011 0.0019 0.0018
Schistosoma mansoni tyrosine kinase 0.0052 0.0422 0.0421
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0564 1
Schistosoma mansoni cytochrome P450 0.0011 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0142 0.0142
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0082 0.0081
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0031 0.0216 0.2535
Giardia lamblia UDP-N-acetylglucosamine-dolichyl-phosphateN-acetylglucosaminephosphotransferase 0.0019 0.0096 0.2204
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0031 0.0217 0.4898
Echinococcus multilocularis sodium:dicarboxylate symporter 0.1033 1 1
Echinococcus multilocularis excitatory amino acid transporter 2 0.1033 1 1
Loa Loa (eye worm) hypothetical protein 0.009 0.0791 0.0791
Loa Loa (eye worm) hypothetical protein 0.068 0.6557 0.6557
Schistosoma mansoni tar DNA-binding protein 0.0021 0.0119 0.0117
Entamoeba histolytica hypothetical protein 0.0024 0.0148 0.319
Loa Loa (eye worm) agrin synaptic family protein 0.0016 0.007 0.007
Entamoeba histolytica tyrosyl-tRNA synthetase, putative 0.0031 0.0216 0.4874
Echinococcus multilocularis neutral amino acid transporter A 0.1033 1 1
Leishmania major tyrosyl-tRNA synthetase, putative 0.0031 0.0216 0.3608
Plasmodium vivax endoplasmin, putative 0.0011 0.0019 0.0416
Echinococcus multilocularis heat shock protein 90 0.0011 0.0019 0.0018
Brugia malayi Cytochrome P450 family protein 0.0011 0.0023 0.0022
Echinococcus multilocularis GPCR, family 3, C terminal 0.009 0.0791 0.0789
Giardia lamblia Tyrosyl-tRNA synthetase 0.0031 0.0216 0.5241
Toxoplasma gondii heat shock protein 90, putative 0.0011 0.0019 0.0187
Echinococcus granulosus aminoacyl tRNA synthase complex interacting 0.0024 0.0148 0.0146
Echinococcus granulosus glutamate receptor 2 0.0052 0.0422 0.0421
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0026 0.0165 0.0336
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0117 0.0117
Brugia malayi Pre-SET motif family protein 0.0069 0.0584 0.0582
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0143 0.0141
Plasmodium falciparum tyrosine--tRNA ligase 0.0031 0.0216 1
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0023 0.0022
Schistosoma mansoni DNA helicase recq5 0.001 0.0009 0.0007
Brugia malayi Cytochrome P450 family protein 0.0021 0.0117 0.0115
Brugia malayi jmjC domain containing protein 0.0017 0.0082 0.0081
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.0165 0.0142
Brugia malayi hypothetical protein 0.003 0.0209 0.0208
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0011 0.0023 0.0099
Entamoeba histolytica hypothetical protein 0.003 0.0209 0.4717
Brugia malayi RNA recognition motif domain containing protein 0.0021 0.0119 0.0117
Brugia malayi Cytochrome P450 family protein 0.0037 0.0277 0.0276
Echinococcus granulosus L aminoadipate semialdehyde 0.0091 0.0803 0.0802
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0117 0.2423
Plasmodium vivax heat shock protein 86, putative 0.0011 0.0019 0.0416
Echinococcus multilocularis Excitatory amino acid transporter 0.1033 1 1
Loa Loa (eye worm) glutaminase 0.009 0.0794 0.0794
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0142 0.1298 0.1298
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Brugia malayi glutaminase DH11.1 0.009 0.0794 0.0792
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0458 0.4385 0.4384
Loa Loa (eye worm) hypothetical protein 0.0017 0.0082 0.0082
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0038 0.0289 0.0288
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0148 0.319
Echinococcus multilocularis Excitatory amino acid transporter 0.1033 1 1
Leishmania major tyrosyl or methionyl-tRNA synthetase-like protein 0.0024 0.0148 0.2361
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0143 0.1594
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0007
Plasmodium falciparum heat shock protein 90 0.0011 0.0019 0.0503
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0031 0.0217 0.0215
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0009 0.0007
Echinococcus multilocularis receptor type guanylyl cyclase 0.0052 0.0422 0.0421
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0143 0.0141
Brugia malayi TAR-binding protein 0.0021 0.0119 0.0117
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0143 0.1594
Schistosoma mansoni glutamate receptor NMDA 0.0052 0.0422 0.0421
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0148 0.1659
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0016 0.007 0.1105
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0037 0.0709
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.0165 0.2808
Toxoplasma gondii LsmAD domain-containing protein 0.0021 0.0121 0.2024
Mycobacterium tuberculosis Probable threonine dehydratase IlvA 0.005 0.0403 0.0381
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.007
Onchocerca volvulus Putative organic anion transporter 0.0023 0.0142 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0217 0.2548
Schistosoma mansoni metabotropic glutamate receptor 0.0269 0.2545 0.2544
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0016 0.007 0.0069
Echinococcus multilocularis expressed protein 0.0037 0.0272 0.027
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0043
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0024 0.0148 0.319
Loa Loa (eye worm) endoplasmin 0.0011 0.0019 0.0019
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0016 0.007 0.0069
Echinococcus granulosus sodium:dicarboxylate symporter 0.1033 1 1
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0082 0.0081
Brugia malayi Endoplasmin precursor 0.0011 0.0019 0.0018
Toxoplasma gondii methionyl-tRNA synthetase 0.0024 0.0148 0.2505
Loa Loa (eye worm) RNA binding protein 0.0021 0.0119 0.0119
Onchocerca volvulus 0.0019 0.0096 0.0094
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0011 0.0023 0.0073
Schistosoma mansoni agrin 0.0016 0.007 0.0069
Schistosoma mansoni glutaminase 0.009 0.0794 0.0792
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0277 0.0277
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0011 0.0023 0.026
Brugia malayi jmjC domain containing protein 0.0064 0.0543 0.0542
Brugia malayi sodium-independent organic anion transporter family protein 0.0023 0.0142 0.0141
Trichomonas vaginalis threonine dehydratase/deaminase, putative 0.005 0.0403 0.4959
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0263 0.6055
Echinococcus multilocularis follistatin 0.0016 0.007 0.0069
Chlamydia trachomatis neutral amino acid transporter 0.0458 0.4385 0.4301
Echinococcus granulosus expressed protein 0.0037 0.0272 0.027
Schistosoma mansoni hypothetical protein 0.003 0.0209 0.0208
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0019 0.0096 0.19
Echinococcus multilocularis acetylcholinesterase 0.0013 0.0043 0.0041
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0031 0.0217 0.0215
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0038 0.0289 0.0288
Loa Loa (eye worm) heat shock protein 90 0.0011 0.0019 0.0019
Loa Loa (eye worm) RecQ helicase 0.0023 0.0143 0.0143
Loa Loa (eye worm) cytochrome P450 0.0011 0.0023 0.0023
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0009 0.0007
Schistosoma mansoni metabotropic glutamate receptor 0.0463 0.4435 0.4434
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0009 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0021 0.0121 0.543
Onchocerca volvulus 0.0091 0.0803 0.0802
Entamoeba histolytica hypothetical protein 0.0026 0.0165 0.3607
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0501 0.4803 0.4802
Entamoeba histolytica threonine dehydratase, putative 0.005 0.0403 0.9533
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0564 0.0562
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0011 0.0009
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0543 0.0542
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0263 0.4586
Loa Loa (eye worm) carboxylesterase 0.0013 0.0043 0.0043
Echinococcus granulosus ubiquitin specific protease 41 0.0031 0.0217 0.0215
Loa Loa (eye worm) glutamate receptor 0.0217 0.2037 0.2037
Entamoeba histolytica hypothetical protein 0.0024 0.0148 0.319
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.007
Echinococcus multilocularis acetylcholinesterase 0.0013 0.0043 0.0041
Brugia malayi hypothetical protein 0.0021 0.0121 0.012
Brugia malayi SPARC precursor 0.0016 0.007 0.0069
Onchocerca volvulus 0.0052 0.0422 0.0421
Schistosoma mansoni organic anion transporter 0.0023 0.0142 0.0141
Echinococcus granulosus metabotropic glutamate receptor 2 0.0463 0.4435 0.4434
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0024 0.0148 0.319
Echinococcus granulosus excitatory amino acid transporter 2 0.1033 1 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0021 0.0119 0.0119
Schistosoma mansoni tar DNA-binding protein 0.0021 0.0119 0.0117
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.0165 0.267
Treponema pallidum glutamate/aspartate transporter 0.0458 0.4385 1
Brugia malayi hypothetical protein 0.0078 0.0675 0.0674
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0019 0.0096 0.19
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0082 0.0081
Brugia malayi metabotropic glutamate receptor type 2 0.0269 0.2545 0.2544
Echinococcus granulosus bloom syndrome protein 0.0023 0.0143 0.0141
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0142 0.1298 0.1298
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.001 0.0011 0.0034
Leishmania major extracellular receptor, putative 0.0052 0.0422 0.7403
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0009 0.0007 0.0006
Toxoplasma gondii tRNA binding domain-containing protein 0.0024 0.0148 0.2505
Brugia malayi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.0019 0.0096 0.0094
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0031 0.0217 0.0215
Brugia malayi jmjC domain containing protein 0.0017 0.0082 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0021 0.0119 0.0117
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.00000000077277
Leishmania major serine-threonine dehydratase, putative 0.005 0.0403 0.7057
Brugia malayi Receptor family ligand binding region containing protein 0.0052 0.0422 0.0421
Brugia malayi sodium-independent organic anion transporter family protein 0.0023 0.0142 0.0141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0038 0.0289 0.0288
Toxoplasma gondii glycosyl transferase, group 4 family protein 0.0019 0.0096 0.1567
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0052 0.0422 0.0421
Leishmania major UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.0019 0.0096 0.1406
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0887 0.8578 0.8577
Onchocerca volvulus Putative organic anion transporter 0.0023 0.0142 0.0141
Onchocerca volvulus Serine racemase homolog 0.005 0.0403 0.0402
Plasmodium vivax methionine-tRNA ligase, putative 0.0024 0.0148 0.6689
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0082 0.0082
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0091 0.0803 0.0802
Leishmania major hypothetical protein, conserved 0.0017 0.0082 0.1159
Loa Loa (eye worm) hypothetical protein 0.0052 0.0422 0.0422
Loa Loa (eye worm) intermediate filament protein 0.0009 0.0002 0.0002
Schistosoma mansoni rotamase 0.0037 0.0272 0.027
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0082 0.3553
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0272 0.3258
Loa Loa (eye worm) hypothetical protein 0.0031 0.0217 0.0217
Onchocerca volvulus 0.0052 0.0422 0.0421
Echinococcus granulosus phd:f box containing protein 0.0017 0.0082 0.0081
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0117 0.2423
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0067 0.105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0038 0.0289 0.0288
Trichomonas vaginalis set domain proteins, putative 0.0078 0.0676 0.8485
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0263 0.6055
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0165 0.0336

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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