Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | raf serine:threonine protein kinase | 0.0214 | 0.0637 | 0.0637 |
Brugia malayi | Nuclear hormone receptor E75 | 0.006 | 0.0098 | 0.0098 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0063 | 0.0107 | 0.0107 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0047 | 0.0047 |
Brugia malayi | steroid hormone receptor | 0.0237 | 0.0721 | 0.0721 |
Brugia malayi | nuclear receptor RXR | 0.0177 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0034 | 0.0004 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Onchocerca volvulus | 0.0046 | 0.0047 | 0.0062 | |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0092 | 0.0211 | 0.0211 |
Onchocerca volvulus | 0.0171 | 0.0487 | 0.0645 | |
Brugia malayi | Carboxylesterase family protein | 0.0063 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0126 | 0.0126 |
Brugia malayi | hexokinase type II | 0.0054 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0126 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0211 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0092 | 0.0211 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0237 | 0.0721 | 0.0955 |
Brugia malayi | conserved hypotetical protein | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Brugia malayi | Hexokinase family protein | 0.0171 | 0.0487 | 0.0487 |
Onchocerca volvulus | 0.0063 | 0.0107 | 0.0142 | |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.2877 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0126 | 0.0126 |
Trypanosoma brucei | hexokinase, putative | 0.0171 | 0.0487 | 0.0264 |
Brugia malayi | nuclear hormone receptor | 0.0237 | 0.0721 | 0.0721 |
Schistosoma mansoni | hypothetical protein | 0.0159 | 0.0444 | 0.3714 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Brugia malayi | nuclear receptor NHR-67 | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0237 | 0.0721 | 0.0721 |
Leishmania major | hexokinase, putative | 0.0171 | 0.0487 | 0.0264 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0237 | 0.0721 | 0.0721 |
Onchocerca volvulus | 0.007 | 0.0132 | 0.0175 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus granulosus | FTZ F1 alpha | 0.0237 | 0.0721 | 0.0721 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0177 | 0.0508 | 0.0508 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0047 | 0.005 | 0.0417 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0063 | 0.0107 | 0.0896 |
Echinococcus multilocularis | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Echinococcus granulosus | carboxylesterase 5A | 0.0372 | 0.1195 | 0.1195 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0132 | 0.0132 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.006 | 0.0098 | 0.0098 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0177 | 0.0508 | 0.0508 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0237 | 0.0721 | 0.6031 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0214 | 0.0637 | 0.5327 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0132 | 0.0132 |
Brugia malayi | Carboxylesterase family protein | 0.0063 | 0.0107 | 0.0107 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.006 | 0.0098 | 0.0821 |
Onchocerca volvulus | 0.0063 | 0.0107 | 0.0142 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0372 | 0.1195 | 0.1195 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0034 | 0.0004 | 0.0004 |
Brugia malayi | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Schistosoma mansoni | nuclear hormone receptor | 0.006 | 0.0098 | 0.0821 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0237 | 0.0721 | 0.0721 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0092 | 0.0211 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | nuclear receptor | 0.006 | 0.0098 | 0.0821 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0063 | 0.0107 | 0.5038 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0372 | 0.1195 | 0.1195 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0068 | 0.0126 | 0.0126 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0237 | 0.0721 | 0.6031 |
Loa Loa (eye worm) | carboxylesterase | 0.0063 | 0.0107 | 0.0107 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0237 | 0.0721 | 0.0955 |
Echinococcus granulosus | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Echinococcus multilocularis | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Plasmodium vivax | hexokinase, putative | 0.0171 | 0.0487 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | acetylcholinesterase | 0.0372 | 0.1195 | 0.1195 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0063 | 0.0107 | 0.0107 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0214 | 0.0637 | 0.0637 |
Brugia malayi | tailless protein | 0.006 | 0.0098 | 0.0098 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0237 | 0.0721 | 0.0721 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0047 | 0.005 | 0.0417 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.006 | 0.0098 | 0.0098 |
Toxoplasma gondii | peptidase family M13 protein | 0.0092 | 0.0211 | 0.4307 |
Echinococcus granulosus | cytochrome c | 0.0098 | 0.0229 | 0.0229 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.2877 | 1 | 1 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.2877 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0063 | 0.0107 | 0.5 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Onchocerca volvulus | 0.0237 | 0.0721 | 0.0955 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0177 | 0.0508 | 0.0508 |
Entamoeba histolytica | hexokinase 2 | 0.0171 | 0.0487 | 1 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.007 | 0.0132 | 0.0132 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0063 | 0.0107 | 0.0896 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0063 | 0.0107 | 0.0896 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0211 | 0.0211 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0063 | 0.0107 | 0.0896 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0034 | 0.0004 | 0.0004 |
Onchocerca volvulus | 0.0063 | 0.0107 | 0.0142 | |
Brugia malayi | ecdysone receptor | 0.006 | 0.0098 | 0.0098 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0063 | 0.0107 | 0.0107 |
Trypanosoma cruzi | hexokinase, putative | 0.0171 | 0.0487 | 0.0264 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | acetylcholinesterase | 0.0372 | 0.1195 | 0.1195 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0177 | 0.0508 | 0.0508 |
Schistosoma mansoni | coup transcription factor | 0.0237 | 0.0721 | 0.6031 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0296 | 0.0296 |
Schistosoma mansoni | hexokinase | 0.0171 | 0.0487 | 0.4075 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | TKL/RAF/RAF protein kinase | 0.0121 | 0.0312 | 0.0312 |
Schistosoma mansoni | thyroid hormone receptor | 0.0237 | 0.0721 | 0.6031 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0237 | 0.0721 | 0.6031 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | hypothetical protein | 0.0159 | 0.0444 | 0.3714 |
Schistosoma mansoni | acetylcholinesterase | 0.0063 | 0.0107 | 0.0896 |
Loa Loa (eye worm) | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Trypanosoma cruzi | hexokinase, putative | 0.0171 | 0.0487 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0237 | 0.0721 | 0.0721 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0237 | 0.0721 | 0.6031 |
Loa Loa (eye worm) | DR-78 | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | nuclear hormone receptor | 0.006 | 0.0098 | 0.0821 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0237 | 0.0721 | 0.0721 |
Plasmodium falciparum | cytochrome c, putative | 0.0098 | 0.0229 | 0.4682 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0063 | 0.0107 | 0.0107 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.006 | 0.0098 | 0.0821 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0126 | 0.0126 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0092 | 0.0211 | 0.0211 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus granulosus | geminin | 0.0159 | 0.0444 | 0.0444 |
Leishmania major | hexokinase, putative | 0.0171 | 0.0487 | 0.0264 |
Echinococcus granulosus | neuroligin | 0.0063 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | cytochrome c type-1 | 0.0098 | 0.0229 | 0.0229 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0092 | 0.0211 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0107 | 0.0263 | 0.0263 |
Onchocerca volvulus | 0.006 | 0.0098 | 0.013 | |
Brugia malayi | Carboxylesterase family protein | 0.0372 | 0.1195 | 0.1195 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0237 | 0.0721 | 0.0721 |
Brugia malayi | Carboxylesterase family protein | 0.0372 | 0.1195 | 0.1195 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0132 | 0.1106 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0237 | 0.0721 | 0.6031 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0132 | 0.0132 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0237 | 0.0721 | 0.0721 |
Onchocerca volvulus | 0.0171 | 0.0487 | 0.0645 | |
Brugia malayi | nuclear receptor NHR-88 | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0063 | 0.0107 | 0.0107 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.006 | 0.0098 | 0.0098 |
Trypanosoma brucei | hexokinase | 0.0171 | 0.0487 | 0.0264 |
Brugia malayi | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Brugia malayi | Peptidase family M13 containing protein | 0.0092 | 0.0211 | 0.0211 |
Onchocerca volvulus | 0.0171 | 0.0487 | 0.0645 | |
Schistosoma mansoni | nuclear receptor | 0.006 | 0.0098 | 0.0821 |
Brugia malayi | nuclear hormone receptor | 0.006 | 0.0098 | 0.0098 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.2877 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.0171 | 0.0487 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0237 | 0.0721 | 0.6031 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0092 | 0.0211 | 0.1764 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | carboxylesterase | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | Hexokinase family protein | 0.0107 | 0.0263 | 0.0263 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0177 | 0.0508 | 0.0508 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0047 | 0.005 | 0.0417 |
Loa Loa (eye worm) | raf kinase | 0.0213 | 0.0633 | 0.0633 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0047 | 0.005 | 0.0417 |
Onchocerca volvulus | Hexokinase homolog | 0.0107 | 0.0263 | 0.0348 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | carboxylesterase | 0.0372 | 0.1195 | 0.1195 |
Brugia malayi | Nuclear hormone receptor E75 | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0372 | 0.1195 | 0.1195 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.006 | 0.0098 | 0.0098 |
Toxoplasma gondii | cytochrome c, putative | 0.0098 | 0.0229 | 0.4682 |
Brugia malayi | Raf kinase | 0.0206 | 0.061 | 0.061 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0211 | 0.0211 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0132 | 0.0132 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0092 | 0.0211 | 0.0211 |
Entamoeba histolytica | hexokinase 1 | 0.0171 | 0.0487 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0237 | 0.0721 | 0.0721 |
Brugia malayi | Carboxylesterase family protein | 0.0063 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0132 | 0.0132 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.2877 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Plasmodium falciparum | hexokinase | 0.0171 | 0.0487 | 1 |
Wolbachia endosymbiont of Brugia malayi | cytochrome c2 | 0.0098 | 0.0229 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0053 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0068 | 0.0126 | 0.0126 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0237 | 0.0721 | 0.6031 |
Echinococcus granulosus | hexokinase type 2 | 0.0171 | 0.0487 | 0.0487 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Echinococcus multilocularis | cytochrome c | 0.0098 | 0.0229 | 0.0229 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0237 | 0.0721 | 0.6031 |
Echinococcus multilocularis | hexokinase type 2 | 0.0171 | 0.0487 | 0.0487 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.006 | 0.0098 | 0.0821 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Schistosoma mansoni | zinc finger protein | 0.006 | 0.0098 | 0.0821 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0004 | 0.0036 |
Echinococcus multilocularis | geminin | 0.0159 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.007 | 0.0132 | 0.0132 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.2877 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0237 | 0.0721 | 0.0721 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.2877 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.2877 | 1 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.006 | 0.0098 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | Carboxylesterase family protein | 0.0063 | 0.0107 | 0.0107 |
Brugia malayi | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0237 | 0.0721 | 0.0721 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0177 | 0.0508 | 0.4255 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0372 | 0.1195 | 0.1195 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0132 | 0.0132 |
Echinococcus multilocularis | hexokinase | 0.0171 | 0.0487 | 0.0487 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0237 | 0.0721 | 0.0721 |
Schistosoma mansoni | gliotactin | 0.0063 | 0.0107 | 0.0896 |
Onchocerca volvulus | 0.0107 | 0.0263 | 0.0348 | |
Loa Loa (eye worm) | nuclear hormone receptor | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0177 | 0.0508 | 0.4255 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0237 | 0.0721 | 0.0721 |
Onchocerca volvulus | 0.0063 | 0.0107 | 0.0142 | |
Loa Loa (eye worm) | hexokinase type II | 0.0171 | 0.0487 | 0.0487 |
Schistosoma mansoni | cytochrome c | 0.0098 | 0.0229 | 0.1916 |
Echinococcus granulosus | acetylcholinesterase | 0.0372 | 0.1195 | 0.1195 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0237 | 0.0721 | 0.0721 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.006 | 0.0098 | 0.013 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0372 | 0.1195 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0237 | 0.0721 | 0.6031 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Brugia malayi | hypothetical protein | 0.006 | 0.0098 | 0.0098 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0237 | 0.0721 | 0.6031 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0237 | 0.0721 | 0.0721 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.2877 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.2877 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.006 | 0.0098 | 0.0098 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0372 | 0.1195 | 0.1195 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0237 | 0.0721 | 0.0721 |
Treponema pallidum | hexokinase (hxk) | 0.0171 | 0.0487 | 0.5 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.006 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.218 | 0.7548 | 0.7548 |
Brugia malayi | ecdysteroid receptor | 0.218 | 0.7548 | 0.7548 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0047 | 0.005 | 0.0417 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0063 | 0.0107 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.2877 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Toxoplasma gondii | hexokinase | 0.0171 | 0.0487 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0053 | 0.0072 | 0.0072 |
Onchocerca volvulus | 0.0063 | 0.0107 | 0.0142 | |
Brugia malayi | Cytochrome c type-1 | 0.0098 | 0.0229 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Plasmodium vivax | cytochrome c, putative | 0.0098 | 0.0229 | 0.4682 |
Brugia malayi | nuclear receptor NHR-88 | 0.0237 | 0.0721 | 0.0721 |
Onchocerca volvulus | Bile acid receptor homolog | 0.218 | 0.7548 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0063 | 0.0107 | 0.0896 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0107 | 0.0107 |
Onchocerca volvulus | 0.006 | 0.0098 | 0.013 | |
Brugia malayi | hypothetical protein | 0.0034 | 0.0004 | 0.0004 |
Echinococcus multilocularis | neuroligin | 0.0063 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0077 | 0.0077 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.006 | 0.0098 | 0.0098 |
Brugia malayi | hypothetical protein | 0.0177 | 0.0508 | 0.0508 |
Schistosoma mansoni | thyroid hormone receptor | 0.0237 | 0.0721 | 0.6031 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0237 | 0.0721 | 0.0721 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0237 | 0.0721 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.0721 | 0.0721 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.006 | 0.0098 | 0.0098 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 1.6 nM | Inhibition of [3H]- oxytocin binding to rat uterine Oxytocin receptor | ChEMBL. | 2163451 |
Ki (binding) | = 320 nM | Inhibition of [3H]-arginine vasopressin binding to rat kidney medulla Vasopressin V2 receptor | ChEMBL. | 2163451 |
Ki (binding) | = 760 nM | Inhibition of [3H]-arginine vasopressin binding to rat liver Vasopressin V1 receptor | ChEMBL. | 2163451 |
S | = 0.08 mg ml-1 | Solubility of the compound at 25 degree C and pH of 6.6 | ChEMBL. | 2163451 |
S | = 1.5 mg ml-1 | Solubility of the compound at 25 degree C and pH of 5.0 | ChEMBL. | 2163451 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.