Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear receptor NHR-88 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0159 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.03 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.03 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.03 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.03 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0159 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.03 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.03 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.03 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.03 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.03 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0159 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.03 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.03 | 1 | 1 |
Onchocerca volvulus | 0.03 | 1 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.03 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0159 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.03 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.03 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.03 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.03 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.03 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Schistosoma mansoni | thyroid hormone receptor | 0.03 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.03 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0159 | 0.1071 | 0.1071 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.03 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.03 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0151 | 0.0607 | 0.0607 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.03 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.03 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.03 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.03 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.03 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.03 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.03 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.03 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.03 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.03 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.03 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.03 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Brugia malayi | hypothetical protein | 0.0159 | 0.1071 | 0.1071 |
Onchocerca volvulus | Bile acid receptor homolog | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.03 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.03 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0159 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0151 | 0.0607 | 0.0607 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0159 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0159 | 0.1071 | 0.1071 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.03 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.03 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.03 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.