Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0298 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0298 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.015 | 0.0592 | 0.0592 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0298 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0298 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0298 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0298 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0298 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0157 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0298 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0298 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0298 | 1 | 1 |
Onchocerca volvulus | 0.0298 | 1 | 1 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0298 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0298 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0298 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0298 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0298 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0298 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0298 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0298 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0157 | 0.1071 | 0.1071 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0298 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0298 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0298 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0298 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0298 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0157 | 0.1071 | 0.1071 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0298 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0298 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0298 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0157 | 0.1071 | 0.1071 |
Brugia malayi | steroid hormone receptor | 0.0298 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0157 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0157 | 0.1071 | 0.1071 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0298 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0298 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.015 | 0.0592 | 0.0592 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0298 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0157 | 0.1071 | 0.1071 |
Schistosoma mansoni | coup transcription factor | 0.0298 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0298 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0298 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0298 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0157 | 0.1071 | 0.1071 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0157 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0298 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.