Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Onchocerca volvulus | 0.0298 | 1 | 1 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0298 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0298 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0158 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.3908 | 0.3908 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0298 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0202 | 0.3908 | 0.3908 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0298 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0202 | 0.3908 | 0.3908 |
Brugia malayi | nuclear hormone receptor | 0.0298 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0298 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0298 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.3908 | 0.3908 |
Onchocerca volvulus | 0.0202 | 0.3908 | 0.3908 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0298 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.3908 | 0.3908 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0298 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0298 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0298 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Echinococcus multilocularis | peroxidasin | 0.0202 | 0.3908 | 0.3908 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.015 | 0.0564 | 0.0564 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0298 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0158 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Echinococcus granulosus | FTZ F1 alpha | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0298 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0298 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0158 | 0.1071 | 0.1071 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0298 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.3908 | 0.3908 |
Onchocerca volvulus | Dual oxidase homolog | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0298 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0158 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0298 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0298 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0158 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.3908 | 0.3908 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0298 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0158 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0298 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0298 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0298 | 1 | 1 |
Onchocerca volvulus | 0.0202 | 0.3908 | 0.3908 | |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0202 | 0.3908 | 0.3908 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Onchocerca volvulus | Peroxidasin homolog | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0298 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.3908 | 0.3908 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0298 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.3908 | 0.3908 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0298 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0298 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0158 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0158 | 0.1071 | 0.1071 |
Onchocerca volvulus | 0.0202 | 0.3908 | 0.3908 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0298 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.3908 | 0.3908 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0298 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0298 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0298 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0298 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0298 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0298 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.015 | 0.0564 | 0.0564 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0298 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0298 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0298 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0298 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.3908 | 0.3908 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.3908 | 0.3908 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0298 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.