Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0296 | 0.0284 | 0.0369 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1456 | 0.1611 | 0.2088 |
Brugia malayi | Telomerase reverse transcriptase | 0.014 | 0.0106 | 0.0137 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.1381 | 0.1526 | 0.1978 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0296 | 0.0284 | 0.0369 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyX (ts) (TSase) | 0.8792 | 1 | 1 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0459 | 0.0471 | 0.0611 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0217 | 0.0195 | 0.0195 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0337 |
Schistosoma mansoni | gliotactin | 0.0246 | 0.0227 | 0.0263 |
Plasmodium falciparum | thymidylate kinase | 0.0478 | 0.0493 | 0.0617 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0478 | 0.0493 | 0.0427 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0158 | 0.0127 | 0.0159 |
Brugia malayi | dihydrofolate reductase family protein | 0.0453 | 0.0465 | 0.0602 |
Onchocerca volvulus | 0.0296 | 0.0284 | 0.0313 | |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0119 | 0.0083 | 0.0083 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0246 | 0.0227 | 0.0263 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0188 | 0.0161 | 0.0201 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0337 |
Entamoeba histolytica | thymidine kinase, putative | 0.0421 | 0.0428 | 0.865 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0337 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0246 | 0.0227 | 0.0295 |
Echinococcus multilocularis | DNA polymerase alpha catalytic subunit | 0.0166 | 0.0136 | 0.0177 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0227 | 0.0205 | 0.021 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0246 | 0.0227 | 0.0263 |
Toxoplasma gondii | DNA polymerase | 0.0202 | 0.0177 | 0.0222 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.0203 | 0.0203 |
Echinococcus granulosus | DNA polymerase subunit gamma | 0.0069 | 0.0025 | 0.0032 |
Schistosoma mansoni | thymidylate kinase | 0.0478 | 0.0493 | 0.0609 |
Plasmodium falciparum | DNA polymerase alpha catalytic subunit A | 0.0056 | 0.001 | 0.0013 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0052 | 0.0006 | 0.0008 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0421 | 0.0428 | 0.1174 |
Entamoeba histolytica | DNA polymerase delta catalytic subunit, putative | 0.0202 | 0.0177 | 0.3455 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0107 | 0.0069 | 0.0069 |
Trypanosoma brucei | unspecified product | 0.0192 | 0.0166 | 0.0208 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0058 | 0.0012 | 0.0016 |
Brugia malayi | Dihydrofolate reductase | 0.0453 | 0.0465 | 0.0602 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0337 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0052 | 0.0006 | 0.0008 |
Echinococcus granulosus | acetylcholinesterase | 0.1456 | 0.1611 | 0.2088 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.1353 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0296 | 0.0284 | 0.0356 |
Leishmania major | DNA polymerase delta catalytic subunit, putative | 0.0202 | 0.0177 | 0.0222 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0453 | 0.0465 | 0.0465 |
Plasmodium vivax | hypothetical protein, conserved | 0.0296 | 0.0284 | 0.0356 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0296 | 0.0284 | 0.0369 |
Brugia malayi | DNA polymerase alpha catalytic subunit | 0.0145 | 0.0112 | 0.0146 |
Trypanosoma brucei | DNA polymerase epsilon catalytic subunit, putative | 0.0085 | 0.0044 | 0.0055 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0195 | 0.0169 | 0.0212 |
Onchocerca volvulus | 0.6794 | 0.7716 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.0184 | 0.0239 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1456 | 0.1611 | 0.2088 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0421 | 0.0428 | 0.0536 |
Giardia lamblia | DNA polymerase delta, catalytic subunit | 0.0202 | 0.0177 | 0.3509 |
Giardia lamblia | Ribonuclease H | 0.0158 | 0.0127 | 0.2474 |
Plasmodium vivax | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.0617 |
Brugia malayi | thymidylate kinase | 0.0478 | 0.0493 | 0.0639 |
Loa Loa (eye worm) | DNA polymerase epsilon catalytic subunit | 0.0047 | 0 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.1735 | 0.193 | 0.2477 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0052 | 0.0006 | 0.0008 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0337 |
Echinococcus granulosus | DNA polymerase alpha catalytic subunit | 0.0166 | 0.0136 | 0.0177 |
Schistosoma mansoni | phosphoglucomutase | 0.0158 | 0.0127 | 0.0132 |
Plasmodium falciparum | amino acid transporter, putative | 0.0296 | 0.0284 | 0.0356 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1456 | 0.1611 | 0.2062 |
Echinococcus multilocularis | ribonuclease H1 | 0.0158 | 0.0127 | 0.0164 |
Schistosoma mansoni | thymidylate kinase | 0.0478 | 0.0493 | 0.0609 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0103 | 0.0064 | 0.0176 |
Onchocerca volvulus | 0.0246 | 0.0227 | 0.0239 | |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0413 | 0.0418 | 0.0523 |
Leishmania major | thymidylate kinase-like protein | 0.0478 | 0.0493 | 0.0617 |
Trypanosoma brucei | thymidine kinase | 0.0421 | 0.0428 | 0.0536 |
Brugia malayi | RNase H family protein | 0.0158 | 0.0127 | 0.0164 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0246 | 0.0227 | 0.0033 |
Schistosoma mansoni | DNA polymerase delta catalytic subunit | 0.0202 | 0.0177 | 0.0198 |
Plasmodium vivax | DNA polymerase zeta catalytic subunit, putative | 0.0085 | 0.0044 | 0.0055 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0246 | 0.0227 | 0.0295 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.1381 | 0.1526 | 0.1978 |
Giardia lamblia | Thymidine kinase | 0.0421 | 0.0428 | 0.8661 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0058 | 0.0012 | 0.0016 |
Plasmodium falciparum | transporter, putative | 0.0296 | 0.0284 | 0.0356 |
Brugia malayi | Carboxylesterase family protein | 0.1456 | 0.1611 | 0.2088 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0049 | 0.0032 |
Trypanosoma brucei | DNA polymerase zeta catalytic subunit, putative | 0.0085 | 0.0044 | 0.0055 |
Schistosoma mansoni | DNA polymerase alpha catalytic subunit | 0.0166 | 0.0136 | 0.0145 |
Onchocerca volvulus | DNA polymerase delta catalytic subunit homolog | 0.0202 | 0.0177 | 0.0174 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0369 |
Plasmodium vivax | DNA polymerase epsilon, catalytic subunit a, putative | 0.0085 | 0.0044 | 0.0055 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0296 | 0.0284 | 0.0369 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0107 | 0.0069 | 0.0069 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0337 |
Echinococcus multilocularis | thymidylate kinase | 0.0478 | 0.0493 | 0.0639 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0246 | 0.0227 | 0.0295 |
Toxoplasma gondii | hypothetical protein | 0.0296 | 0.0284 | 0.0356 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0049 | 0.0032 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0049 | 0.0064 |
Trypanosoma brucei | RNA helicase, putative | 0.1735 | 0.193 | 0.2415 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0195 | 0.0169 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Plasmodium vivax | DNA polymerase delta catalytic subunit, putative | 0.0202 | 0.0177 | 0.0222 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0052 | 0.0006 | 0.0008 |
Leishmania major | hypothetical protein, conserved | 0.0188 | 0.0161 | 0.0201 |
Echinococcus granulosus | DNA polymerase delta catalytic subunit | 0.0202 | 0.0177 | 0.0229 |
Echinococcus granulosus | neuroligin | 0.0246 | 0.0227 | 0.0295 |
Leishmania major | ribonuclease H1, putative | 0.0158 | 0.0127 | 0.0159 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7035 | 0.7991 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.7035 | 0.7991 | 1 |
Trypanosoma brucei | DNA polymerase delta catalytic subunit, putative | 0.0202 | 0.0177 | 0.0222 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0296 | 0.0284 | 0.0337 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0296 | 0.0284 | 0.0369 |
Trichomonas vaginalis | DNA polymerase delta catalytic subunit, putative | 0.0085 | 0.0044 | 0.0119 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0049 | 0.0064 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0453 | 0.0465 | 0.8634 |
Mycobacterium ulcerans | thymidylate kinase | 0.0478 | 0.0493 | 0.0305 |
Mycobacterium tuberculosis | Probable reductase | 0.0107 | 0.0069 | 0.0069 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0192 | 0.0166 | 0.0208 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.0617 |
Toxoplasma gondii | hypothetical protein | 0.0067 | 0.0022 | 0.0028 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0154 | 0.0123 | 0.0154 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0049 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0246 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.1456 | 0.1611 | 0.2088 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0246 | 0.0227 | 0.0263 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.0227 | 0.0295 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0158 | 0.0127 | 0.0108 |
Onchocerca volvulus | 0.0246 | 0.0227 | 0.0239 | |
Trypanosoma brucei | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.0617 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.0471 | 0.0611 |
Onchocerca volvulus | 0.0246 | 0.0227 | 0.0239 | |
Toxoplasma gondii | thymidylate kinase | 0.0478 | 0.0493 | 0.0617 |
Mycobacterium tuberculosis | Hypothetical protein | 0.3232 | 0.3642 | 0.3642 |
Giardia lamblia | CDC8 | 0.0478 | 0.0493 | 1 |
Onchocerca volvulus | DNA polymerase alpha catalytic subunit homolog | 0.0208 | 0.0184 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Trypanosoma brucei | ribonuclease H1 | 0.0158 | 0.0127 | 0.0159 |
Trypanosoma cruzi | DNA polymerase I alpha catalytic subunit, putative | 0.0103 | 0.0064 | 0.0081 |
Brugia malayi | RNase H family protein | 0.0158 | 0.0127 | 0.0164 |
Loa Loa (eye worm) | carboxylesterase | 0.0246 | 0.0227 | 0.0295 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0453 | 0.0465 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.0284 | 0.0369 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0478 | 0.0493 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0246 | 0.0227 | 0.0295 |
Chlamydia trachomatis | thymidylate kinase | 0.0478 | 0.0493 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0049 | 0.0064 |
Giardia lamblia | DNA polymerase epsilon, catalytic subunit | 0.0085 | 0.0044 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.1381 | 0.1526 | 0.1978 |
Toxoplasma gondii | DNA polymerase family B protein | 0.0085 | 0.0044 | 0.0055 |
Schistosoma mansoni | DNA polymerase epsilon catalytic subunit | 0.0085 | 0.0044 | 0.0025 |
Loa Loa (eye worm) | thymidylate kinase | 0.0478 | 0.0493 | 0.0639 |
Loa Loa (eye worm) | hypothetical protein | 0.1456 | 0.1611 | 0.2088 |
Brugia malayi | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0296 | 0.0284 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.0284 | 0.0369 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0119 | 0.0083 | 0.0014 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0246 | 0.0227 | 0.0623 |
Schistosoma mansoni | phosphoglucomutase | 0.0158 | 0.0127 | 0.0132 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0049 | 0.0064 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0459 | 0.0471 | 0.058 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.6794 | 0.7716 | 0.7716 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0049 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Trichomonas vaginalis | DNA polymerase alpha catalytic subunit, putative | 0.0085 | 0.0044 | 0.0119 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.3232 | 0.3642 | 0.4558 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0107 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.0284 | 0.0369 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0453 | 0.0465 | 0.0275 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0453 | 0.0465 | 0.0602 |
Brugia malayi | DNA polymerase family B, exonuclease domain containing protein | 0.0085 | 0.0044 | 0.0057 |
Echinococcus multilocularis | hypothetical protein | 0.0069 | 0.0025 | 0.0032 |
Leishmania major | thymidine kinase, putative | 0.0421 | 0.0428 | 0.0536 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0058 | 0.0012 | 0.0016 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0421 | 0.0428 | 0.1174 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0246 | 0.0227 | 0.0623 |
Echinococcus granulosus | dna polymerase epsilon catalytic subunit a | 0.0085 | 0.0044 | 0.0057 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.1353 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7035 | 0.7991 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.0284 | 0.0369 |
Echinococcus multilocularis | neuroligin | 0.0246 | 0.0227 | 0.0295 |
Trypanosoma cruzi | DNA polymerase delta catalytic subunit, putative | 0.0202 | 0.0177 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0 | 0.0001 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.1381 | 0.1526 | 0.1978 |
Echinococcus granulosus | DNA polymerase zeta catalytic subunit | 0.0085 | 0.0044 | 0.0057 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0192 | 0.0166 | 0.0208 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0071 | 0.0027 | 0.0034 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0296 | 0.0284 | 0.0337 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0119 | 0.0083 | 0.0083 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0158 | 0.0127 | 0.0159 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0478 | 0.0493 | 1 |
Echinococcus multilocularis | DNA polymerase zeta catalytic subunit | 0.0085 | 0.0044 | 0.0057 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0453 | 0.0465 | 0.0398 |
Giardia lamblia | DNA polymerase alpha subunit A | 0.0119 | 0.0082 | 0.1561 |
Toxoplasma gondii | hypothetical protein | 0.0296 | 0.0284 | 0.0356 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0246 | 0.0227 | 0.0263 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0413 | 0.0418 | 0.0523 |
Brugia malayi | DNA polymerase family B containing protein | 0.0085 | 0.0044 | 0.0057 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0296 | 0.0284 | 0.0356 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0296 | 0.0284 | 0.0356 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0246 | 0.0227 | 0.0227 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0107 | 0.0069 | 0.0069 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0296 | 0.0284 | 0.0369 |
Brugia malayi | Carboxylesterase family protein | 0.1456 | 0.1611 | 0.2088 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0296 | 0.0284 | 0.0369 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0246 | 0.0227 | 0.0227 |
Plasmodium falciparum | DNA polymerase epsilon catalytic subunit A, putative | 0.0047 | 0 | 0.0001 |
Echinococcus multilocularis | DNA polymerase delta catalytic subunit | 0.0202 | 0.0177 | 0.0229 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0296 | 0.0284 | 0.0369 |
Echinococcus granulosus | carboxylesterase 5A | 0.1456 | 0.1611 | 0.2088 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0025 | 0.0032 |
Plasmodium vivax | amine transporter, putative | 0.0296 | 0.0284 | 0.0356 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0192 | 0.0166 | 0.0208 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.1381 | 0.1526 | 0.1978 |
Onchocerca volvulus | 0.0246 | 0.0227 | 0.0239 | |
Mycobacterium ulcerans | FAD-dependent thymidylate synthase | 0.8792 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0246 | 0.0227 | 0.0295 |
Schistosoma mansoni | acetylcholinesterase | 0.0246 | 0.0227 | 0.0263 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0413 | 0.0418 | 0.0523 |
Leishmania major | DNA polymerase epsilon catalytic subunit, putative | 0.0085 | 0.0044 | 0.0055 |
Echinococcus multilocularis | serotonin transporter | 0.0459 | 0.0471 | 0.0611 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0478 | 0.0493 | 0.0493 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.1381 | 0.1526 | 0.1978 |
Echinococcus multilocularis | dna polymerase epsilon catalytic subunit a | 0.0085 | 0.0044 | 0.0057 |
Trypanosoma cruzi | thymidine kinase, putative | 0.0421 | 0.0428 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.0471 | 0.0611 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0052 | 0.0006 | 0.0008 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0246 | 0.0227 | 0.0263 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0459 | 0.0471 | 0.058 |
Trichomonas vaginalis | conserved hypothetical protein | 0.3232 | 0.3642 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1381 | 0.1526 | 0.1978 |
Schistosoma mansoni | DNA polymerase zeta catalytic subunit | 0.0085 | 0.0044 | 0.0025 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0107 | 0.0069 | 0.0069 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0158 | 0.0127 | 0.0347 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0246 | 0.0227 | 0.0295 |
Trichomonas vaginalis | DNA polymerase II, putative | 0.0103 | 0.0064 | 0.0176 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0413 | 0.0418 | 0.0523 |
Onchocerca volvulus | 0.0459 | 0.0471 | 0.0557 | |
Plasmodium falciparum | DNA polymerase delta catalytic subunit | 0.0202 | 0.0177 | 0.0222 |
Loa Loa (eye worm) | carboxylesterase | 0.1456 | 0.1611 | 0.2088 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0296 | 0.0284 | 0.0369 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.0227 | 0.0295 |
Echinococcus multilocularis | acetylcholinesterase | 0.1456 | 0.1611 | 0.2088 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.0617 |
Echinococcus granulosus | ribonuclease H1 | 0.0158 | 0.0127 | 0.0164 |
Trichomonas vaginalis | DNA polymerase zeta catalytic subunit, putative | 0.0202 | 0.0177 | 0.0485 |
Brugia malayi | DNA polymerase delta catalytic subunit | 0.0202 | 0.0177 | 0.0229 |
Echinococcus multilocularis | thymidylate synthase | 0.6794 | 0.7716 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.7035 | 0.7991 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0107 | 0.0069 | 0.0069 |
Brugia malayi | hypothetical protein | 0.3232 | 0.3642 | 0.4721 |
Onchocerca volvulus | 0.0246 | 0.0227 | 0.0239 | |
Brugia malayi | hypothetical protein | 0.0296 | 0.0284 | 0.0369 |
Brugia malayi | RNase H family protein | 0.0158 | 0.0127 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.0471 | 0.0611 |
Onchocerca volvulus | 0.0296 | 0.0284 | 0.0313 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0049 | 0.0064 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0052 | 0.0006 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.0227 | 0.0295 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0246 | 0.0227 | 0.0295 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.6794 | 0.7716 | 0.77 |
Trypanosoma brucei | DNA polymerase alpha catalytic subunit | 0.0103 | 0.0064 | 0.0081 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0459 | 0.0471 | 0.9395 |
Trichomonas vaginalis | thymidine kinase, putative | 0.0421 | 0.0428 | 0.1174 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0459 | 0.0471 | 0.0611 |
Leishmania major | DNA polymerase I alpha catalytic subunit, putative | 0.0103 | 0.0064 | 0.0081 |
Echinococcus granulosus | dihydrofolate reductase | 0.0453 | 0.0465 | 0.0602 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.1381 | 0.1526 | 0.1952 |
Schistosoma mansoni | phosphoglucomutase | 0.0158 | 0.0127 | 0.0132 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0052 | 0.0006 | 0.0008 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0478 | 0.0493 | 0.0617 |
Loa Loa (eye worm) | DNA-directed DNA polymerase III | 0.0202 | 0.0177 | 0.0229 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0085 | 0.0044 | 0.0055 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0478 | 0.0493 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0459 | 0.0471 | 0.0611 |
Toxoplasma gondii | DNA polymerase (pol2) superfamily protein | 0.0145 | 0.0112 | 0.014 |
Echinococcus granulosus | thymidylate kinase | 0.0478 | 0.0493 | 0.0639 |
Onchocerca volvulus | 0.0296 | 0.0284 | 0.0313 | |
Echinococcus granulosus | acetylcholinesterase | 0.1456 | 0.1611 | 0.2088 |
Brugia malayi | DNA polymerase I family protein | 0.0069 | 0.0025 | 0.0032 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0192 | 0.0166 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0 | 0.0001 |
Brugia malayi | thymidylate synthase | 0.6794 | 0.7716 | 1 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0188 | 0.0161 | 0.0201 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0195 | 0.0169 | 0.0212 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0119 | 0.0083 | 0.0083 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.0227 | 0.0295 |
Brugia malayi | Carboxylesterase family protein | 0.0246 | 0.0227 | 0.0295 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.1381 | 0.1526 | 0.1978 |
Echinococcus granulosus | serotonin transporter | 0.0459 | 0.0471 | 0.0611 |
Toxoplasma gondii | ribonuclease HI protein | 0.0158 | 0.0127 | 0.0159 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.1381 | 0.1526 | 0.1952 |
Schistosoma mansoni | hypothetical protein | 0.0478 | 0.0493 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.0284 | 0.0369 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.7035 | 0.7991 | 1 |
Plasmodium vivax | DNA polymerase alpha, putative | 0.0145 | 0.0112 | 0.014 |
Loa Loa (eye worm) | serotonin transporter b | 0.0459 | 0.0471 | 0.0611 |
Echinococcus multilocularis | acetylcholinesterase | 0.1456 | 0.1611 | 0.2088 |
Schistosoma mansoni | dihydrofolate reductase | 0.0453 | 0.0465 | 0.0572 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.7035 | 0.7991 | 1 |
Echinococcus granulosus | thymidylate synthase | 0.6794 | 0.7716 | 1 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.6794 | 0.7716 | 1 |
Trypanosoma cruzi | DNA polymerase epsilon catalytic subunit, putative | 0.0085 | 0.0044 | 0.0055 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0058 | 0.0012 | 0.0016 |
Mycobacterium ulcerans | thymidylate synthase | 0.6794 | 0.7716 | 0.767 |
Loa Loa (eye worm) | thymidylate synthase | 0.6794 | 0.7716 | 1 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0296 | 0.0284 | 0.0369 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0478 | 0.0493 | 0.0586 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.