Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | acetylcholinesterase | 0.0494 | 0.1158 | 0.1158 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.0494 | 0.1158 | 0.5 | |
Echinococcus granulosus | neuroligin | 0.0494 | 0.1158 | 0.1158 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0494 | 0.1158 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0494 | 0.1158 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0494 | 0.1158 | 0.1158 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.0494 | 0.1158 | 0.5 | |
Onchocerca volvulus | 0.0494 | 0.1158 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0494 | 0.1158 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0494 | 0.1158 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2923 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0494 | 0.1158 | 0.1158 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0494 | 0.1158 | 0.1158 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0494 | 0.1158 | 0.1158 |
Brugia malayi | Carboxylesterase family protein | 0.2923 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0494 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.0494 | 0.1158 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.2923 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0494 | 0.1158 | 0.1158 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2923 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2923 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0494 | 0.1158 | 0.1158 |
Echinococcus multilocularis | acetylcholinesterase | 0.2923 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0494 | 0.1158 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0494 | 0.1158 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2923 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2923 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2923 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.2923 | 1 | 1 |
Onchocerca volvulus | 0.0494 | 0.1158 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.2923 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2923 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.