Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0192 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0054 | 0.1105 | 0.0931 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.006 | 0.1336 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0054 | 0.1105 | 0.0931 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | DR-78 | 0.0054 | 0.1105 | 0.0931 |
Schistosoma mansoni | nuclear hormone receptor | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0114 | 0.3262 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | ecdysone receptor | 0.0054 | 0.1105 | 0.2973 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0192 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | nuclear hormone receptor | 0.0054 | 0.1105 | 0.2973 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0114 | 0.3262 | 1 |
Brugia malayi | nuclear receptor RXR | 0.006 | 0.1336 | 0.3726 |
Schistosoma mansoni | hypothetical protein | 0.0302 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0054 | 0.1105 | 0.2973 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1336 | 0.1166 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0054 | 0.1105 | 0.0931 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0114 | 0.3262 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.1336 | 0.3726 |
Onchocerca volvulus | 0.0114 | 0.3262 | 1 | |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0114 | 0.3262 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | nuclear hormone receptor | 0.0054 | 0.1105 | 0.0931 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0054 | 0.1105 | 0.0931 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0114 | 0.3262 | 0.3131 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0192 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0192 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | nuclear hormone receptor | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Schistosoma mansoni | coup transcription factor | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | hypothetical protein | 0.0054 | 0.1105 | 0.2973 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0114 | 0.3262 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0114 | 0.3262 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.006 | 0.1336 | 0.1166 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0114 | 0.3262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1336 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1336 | 0.1166 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0054 | 0.1105 | 0.2973 |
Brugia malayi | nuclear receptor NHR-67 | 0.0054 | 0.1105 | 0.2973 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1336 | 0.1166 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0114 | 0.3262 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0302 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0054 | 0.1105 | 0.2973 |
Schistosoma mansoni | nuclear receptor | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | nuclear receptor NHR-88 | 0.0114 | 0.3262 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0114 | 0.3262 | 0.3131 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | conserved hypotetical protein | 0.0054 | 0.1105 | 0.2973 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | ecdysteroid receptor | 0.0114 | 0.3262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.006 | 0.1336 | 0.3726 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0 | 0.5 |
Brugia malayi | nuclear receptor RXR | 0.0054 | 0.1105 | 0.2973 |
Schistosoma mansoni | nuclear receptor | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0114 | 0.3262 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0114 | 0.3262 | 0.3131 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | zinc finger protein | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | tailless protein | 0.0054 | 0.1105 | 0.2973 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.006 | 0.1336 | 0.1166 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0114 | 0.3262 | 0.3131 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0114 | 0.3262 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0054 | 0.1105 | 0.0931 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1336 | 0.1166 |
Brugia malayi | nuclear receptor NHR-88 | 0.0054 | 0.1105 | 0.2973 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0054 | 0.1105 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1105 | 0.0931 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0114 | 0.3262 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0054 | 0.1105 | 0.0931 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0114 | 0.3262 | 0.3131 |
Echinococcus granulosus | FTZ F1 alpha | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0114 | 0.3262 | 0.3131 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0114 | 0.3262 | 0.3131 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.2061 | 0.6087 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0054 | 0.1105 | 0.0931 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0114 | 0.3262 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0114 | 0.3262 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.006 | 0.1336 | 0.1166 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0054 | 0.1105 | 0.2973 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.006 | 0.1336 | 0.1166 |
Schistosoma mansoni | thyroid hormone receptor | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0114 | 0.3262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | nuclear hormone receptor | 0.0114 | 0.3262 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0114 | 0.3262 | 0.3131 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0054 | 0.1105 | 0.0931 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0054 | 0.1105 | 0.2973 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0114 | 0.3262 | 1 |
Brugia malayi | hypothetical protein | 0.0054 | 0.1105 | 0.2973 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0192 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | hypothetical protein | 0.006 | 0.1336 | 0.3726 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0114 | 0.3262 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0114 | 0.3262 | 0.3131 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.1336 | 0.3726 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0302 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0114 | 0.3262 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0054 | 0.1105 | 0.2973 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3262 | 0.3131 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0114 | 0.3262 | 0.3131 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0114 | 0.3262 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0114 | 0.3262 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0114 | 0.3262 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.