Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | voltage-gated cation channel | 0.0086 | 0.0054 | 0.0054 |
Brugia malayi | Hexokinase family protein | 0.2744 | 0.622 | 0.622 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0086 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hexokinase type II | 0.4374 | 1 | 1 |
Entamoeba histolytica | hexokinase 2 | 0.4374 | 1 | 1 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | hexokinase | 0.4374 | 1 | 1 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Echinococcus multilocularis | hexokinase | 0.4374 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.4374 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.4374 | 1 | 0.5 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0086 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hexokinase | 0.4374 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.4374 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.4374 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.4374 | 1 | 1 |
Loa Loa (eye worm) | calcium channel | 0.0086 | 0.0054 | 0.0054 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0086 | 0.0054 | 0.0054 |
Leishmania major | hexokinase, putative | 0.4374 | 1 | 0.5 |
Plasmodium vivax | hexokinase, putative | 0.4374 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.2744 | 0.622 | 0.622 |
Echinococcus granulosus | hexokinase | 0.4374 | 1 | 1 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Echinococcus multilocularis | hexokinase | 0.4374 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2983 | 0.6775 | 0.6775 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Trypanosoma brucei | hexokinase, putative | 0.4374 | 1 | 0.5 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0086 | 0.0054 | 0.0054 |
Schistosoma mansoni | hexokinase | 0.4374 | 1 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0086 | 0.0054 | 0.0054 |
Trypanosoma cruzi | hexokinase, putative | 0.4374 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.4374 | 1 | 1 |
Plasmodium falciparum | hexokinase | 0.4374 | 1 | 0.5 |
Onchocerca volvulus | Hexokinase homolog | 0.2744 | 0.622 | 0.622 |
Brugia malayi | Hexokinase family protein | 0.1353 | 0.2995 | 0.2995 |
Treponema pallidum | hexokinase (hxk) | 0.4374 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.1391 | 0.3081 | 0.3081 |
Leishmania major | hexokinase, putative | 0.4374 | 1 | 0.5 |
Onchocerca volvulus | 0.4374 | 1 | 1 | |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0086 | 0.0054 | 0.0054 |
Onchocerca volvulus | 0.2744 | 0.622 | 0.622 | |
Loa Loa (eye worm) | hypothetical protein | 0.1391 | 0.3081 | 0.3081 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | hexokinase | 0.4374 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.4374 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.4374 | 1 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0086 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hexokinase | 0.1353 | 0.2995 | 0.2995 |
Onchocerca volvulus | 0.4374 | 1 | 1 | |
Onchocerca volvulus | 0.4374 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1391 | 0.3081 | 0.3081 |
Echinococcus multilocularis | hexokinase type 2 | 0.4374 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1146 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1146 | 0.2513 | 0.2513 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Trypanosoma brucei | hexokinase | 0.4374 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.