Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0038 | 0.0224 | 0.0224 |
Brugia malayi | Carboxylesterase family protein | 0.0234 | 0.1644 | 0.1644 |
Brugia malayi | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Echinococcus granulosus | voltage gated potassium channel | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Echinococcus granulosus | carboxylesterase 5A | 0.1385 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0234 | 0.1644 | 0.1644 |
Echinococcus granulosus | acetylcholinesterase | 0.1385 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0038 | 0.0224 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.1385 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1385 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0026 | 0.0026 |
Echinococcus multilocularis | neuroligin | 0.0234 | 0.1644 | 0.1644 |
Onchocerca volvulus | 0.0234 | 0.1644 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0234 | 0.1644 | 0.1644 |
Onchocerca volvulus | 0.0234 | 0.1644 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Echinococcus multilocularis | acetylcholinesterase | 0.1385 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0234 | 0.1644 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1385 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0187 | 0.0187 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0234 | 0.1644 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0234 | 0.1644 | 0.1644 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0234 | 0.1644 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.1385 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.025 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0038 | 0.0224 | 0.0224 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.0026 | 0.0026 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0234 | 0.1644 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0234 | 0.1644 | 0.1644 |
Brugia malayi | Carboxylesterase family protein | 0.1385 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0234 | 0.1644 | 0.1644 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0011 | 0.0026 | 0.0026 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0234 | 0.1644 | 0.1644 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0011 | 0.0026 | 0.0026 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0038 | 0.0224 | 0.0224 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0234 | 0.1644 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0234 | 0.1644 | 0.1644 |
Echinococcus granulosus | acetylcholinesterase | 0.1385 | 1 | 1 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Onchocerca volvulus | 0.0234 | 0.1644 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Loa Loa (eye worm) | hypothetical protein | 0.1385 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0206 | 0.1251 |
Loa Loa (eye worm) | carboxylesterase | 0.0234 | 0.1644 | 0.1644 |
Echinococcus multilocularis | acetylcholinesterase | 0.1385 | 1 | 1 |
Onchocerca volvulus | 0.0234 | 0.1644 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Schistosoma mansoni | gliotactin | 0.0234 | 0.1644 | 0.1644 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0206 | 0.1251 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0234 | 0.1644 | 0.1644 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0234 | 0.1644 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.025 | 0.025 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1644 | 0.1644 |
Onchocerca volvulus | 0.0234 | 0.1644 | 0.5 | |
Echinococcus granulosus | neuroligin | 0.0234 | 0.1644 | 0.1644 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0234 | 0.1644 | 0.1644 |
Brugia malayi | Carboxylesterase family protein | 0.0234 | 0.1644 | 0.1644 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1385 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.