Detailed information for compound 812202

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 382.539 | Formula: C24H34N2O2
  • H donors: 1 H acceptors: 1 LogP: 4.13 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1=CCCCC1)NCC1CCC2(O1)CCN(CC2)Cc1ccccc1C
  • InChi: 1S/C24H34N2O2/c1-19-7-5-6-10-21(19)18-26-15-13-24(14-16-26)12-11-22(28-24)17-25-23(27)20-8-3-2-4-9-20/h5-8,10,22H,2-4,9,11-18H2,1H3,(H,25,27)
  • InChiKey: GJZNNGWGEMACEE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis abcb9, putative 0.0044 0.0052 0.053
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.002 0.0202
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0052 0.053
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Echinococcus granulosus Polycystic kidney disease protein 0.0063 0.0086 0.0367
Echinococcus multilocularis muscleblind protein 1 0.0295 0.0488 0.2086
Trypanosoma cruzi MFS transporter, putative 0.0304 0.0503 0.505
Onchocerca volvulus 0.0025 0.002 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.002 0.0136
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0031 0.003 0.0599
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0104 0.0445
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0084 0.0123 0.0821
Plasmodium vivax unspecified product 0.0014 0 0.0005
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Mycobacterium ulcerans hypothetical protein 0.0036 0.0039 0.0039
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0003 0.0012
Brugia malayi beta-lactamase family protein 0.0036 0.0039 0.026
Brugia malayi Cathepsin L-like cysteine proteinase 0.005 0.0062 0.0418
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0 0.0001
Trypanosoma cruzi major cysteine proteinase, putative 0.0014 0 0.0001
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.003 0.013
Schistosoma mansoni organic anion transporter 0.0304 0.0503 0.2151
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0418
Mycobacterium leprae putative cytochrome p450 0.0019 0.001 0.001
Schistosoma mansoni lozenge 0.011 0.0167 0.0712
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0178 0.1193
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Echinococcus granulosus agrin 0.0177 0.0284 0.1212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0151 0.1544
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.0151 0.0645
Brugia malayi MH2 domain containing protein 0.0117 0.0178 0.1193
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0025 0.002 0.0135
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0043 0.0436
Onchocerca volvulus 0.0036 0.0039 0.0259
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Echinococcus multilocularis 0.0019 0.001 0.0042
Brugia malayi jmjC domain containing protein 0.0031 0.003 0.0202
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0025 0.002 0.0087
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0177 0.0284 0.1899
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0039 0.0039
Brugia malayi jmjC domain containing protein 0.012 0.0183 0.1228
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.0151 0.1514
Loa Loa (eye worm) hypothetical protein 0.0068 0.0095 0.0636
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0048
Mycobacterium tuberculosis Conserved protein 0.0036 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0095 0.0406
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.001 0.001
Mycobacterium ulcerans beta-lactamase 0.0036 0.0039 0.0039
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0001 0.0006
Brugia malayi nuclear receptor NHR-88 0.0025 0.002 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0 0.0001
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0074 0.0105 0.1523
Echinococcus multilocularis cathepsin L 0.0014 0 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.034 0.2274
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0018 0.0176
Brugia malayi Inositol-1 0.0037 0.004 0.0271
Echinococcus granulosus cathepsin L 0.0014 0 0.0001
Echinococcus granulosus ecdysone induced protein 78C 0.0025 0.002 0.0087
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0014 0 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.003 0.013
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0105 0.0448
Loa Loa (eye worm) hypothetical protein 0.0177 0.0284 0.1899
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0103 0.0154 0.0659
Schistosoma mansoni nuclear hormone receptor 0.0025 0.002 0.0087
Echinococcus multilocularis RUN 0.0063 0.0086 0.0367
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0083 0.012 0.1203
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0059 0.0079 0.0526
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0049 0.0062 0.0265
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Giardia lamblia NH3-dependent NAD+ synthetase 0.0082 0.0119 0.1217
Echinococcus granulosus follistatin 0.0177 0.0284 0.1212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Entamoeba histolytica cysteine protease, putative 0.0014 0 0.0001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0038 0.0043 0.0182
Trypanosoma brucei Metacaspase-4 0.0018 0.0007 0.0071
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0052 0.0221
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0014 0 0.0001
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0025 0.002 0.0087
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0006
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0084 0.0123 0.0821
Plasmodium vivax vivapain-1 0.0038 0.0043 0.1433
Echinococcus multilocularis phd:f box containing protein 0.0031 0.003 0.0129
Schistosoma mansoni cathepsin B (C01 family) 0.0014 0 0.0001
Schistosoma mansoni phd/f-box containing protein 0.0031 0.003 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0038 0.0043 0.0428
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0424 0.4343
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0014 0 0.0001
Schistosoma mansoni hypothetical protein 0.0074 0.0105 0.0448
Trypanosoma brucei cysteine peptidase C (CPC) 0.0014 0 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0039 0.0398
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0052 0.053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0025 0.002 0.0136
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0014 0 0.0001
Entamoeba histolytica P-glycoprotein-2, putative 0.0044 0.0052 0.053
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0025 0.002 0.0087
Leishmania major cysteinyl-tRNA synthetase, putative 0.0084 0.0123 0.123
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0018 0.0176
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.004 0.0406
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0039 0.0039
Echinococcus granulosus lysine specific demethylase 6a 0.0031 0.003 0.0129
Echinococcus granulosus caspase 8 0.0018 0.0007 0.003
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.002 0.0292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0202
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0412 0.0689 0.6643
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0025 0.002 0.0295
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Schistosoma mansoni hypothetical protein 0.0048 0.006 0.0257
Onchocerca volvulus 0.0024 0.0018 0.0117
Plasmodium falciparum cysteine proteinase falcipain 3 0.0074 0.0105 0.1523
Mycobacterium ulcerans hypothetical protein 0.0024 0.0018 0.0018
Brugia malayi Papain family cysteine protease containing protein 0.0014 0 0.0001
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.001 0.001
Brugia malayi Papain family cysteine protease containing protein 0.0038 0.0043 0.0285
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0037 0.0379
Echinococcus granulosus multidrug resistance protein 1 0.003 0.0029 0.0124
Giardia lamblia Encystation-specific protease 0.0014 0 0.0001
Echinococcus multilocularis cysteine protease 0.0074 0.0105 0.0449
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0025 0.002 0.0087
Trypanosoma cruzi cruzipain precursor, putative 0.0025 0.0019 0.019
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0014 0 0.0005
Brugia malayi glutaminase DH11.1 0.0274 0.0451 0.3018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0117
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0039 0.0039
Onchocerca volvulus 0.0036 0.0039 0.0259
Onchocerca volvulus Putative organic anion transporter 0.0304 0.0503 0.337
Schistosoma mansoni cpg binding protein 0.006 0.008 0.0344
Trypanosoma cruzi cysteine protease, putative 0.0038 0.0043 0.0428
Brugia malayi beta-lactamase 0.0036 0.0039 0.026
Echinococcus multilocularis cysteine protease 0.0074 0.0105 0.0449
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Mycobacterium tuberculosis Conserved protein 0.0036 0.0039 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.0151 0.0645
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0025 0.002 0.0136
Treponema pallidum cysteinyl-tRNA synthetase 0.0084 0.0123 0.0043
Schistosoma mansoni multidrug resistance protein 0.0044 0.0052 0.0221
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.0151 0.1514
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0304 0.0503 0.2151
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0048 0.006 0.006
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0052 0.0221
Echinococcus multilocularis lysine specific demethylase 6a 0.0031 0.003 0.0129
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.003 0.013
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0036 0.0153
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0103 0.0154 0.0659
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0589 0.0997 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0127
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0154 0.0659
Brugia malayi Cell death protein 3 precursor 0.0059 0.0079 0.0526
Trichomonas vaginalis conserved hypothetical protein 0.0014 0 0.0001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0018 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0037 0.0736
Loa Loa (eye worm) hypothetical protein 0.0876 0.1493 1
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.001 0.001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0074 0.0105 0.0449
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.0151 0.1514
Schistosoma mansoni cathepsin s 0.0025 0.0019 0.0081
Plasmodium falciparum serine repeat antigen 4 0.0014 0 0.0002
Leishmania major cathepsin L-like protease 0.0074 0.0105 0.1053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0048
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Echinococcus multilocularis multidrug resistance protein 1 0.003 0.0029 0.0124
Echinococcus granulosus Ankyrin 0.0015 0.0002 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0424 0.4343
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0003 0.0012
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0044 0.0052 0.1029
Entamoeba histolytica cysteine protease, putative 0.0014 0 0.0001
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0014 0 0.0001
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.004 0.0414
Schistosoma mansoni caspase-7 (C14 family) 0.0059 0.0079 0.0336
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0074 0.0105 0.0449
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Schistosoma mansoni cathepsin F (C01 family) 0.0074 0.0105 0.0449
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0039 0.0398
Mycobacterium leprae Probable lipase LipE 0.0036 0.0039 0.0039
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.004 0.0414
Onchocerca volvulus 0.0304 0.0503 0.337
Mycobacterium tuberculosis Conserved hypothetical protein 0.031 0.0514 0.0514
Plasmodium vivax JmjC domain containing protein 0.0031 0.003 0.1013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0048
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0014 0 0.0005
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0038 0.0043 0.0182
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0039 0.0166
Plasmodium falciparum JmjC domain-containing protein, putative 0.0031 0.003 0.0437
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0033 0.0033 0.0484
Loa Loa (eye worm) hypothetical protein 0.0295 0.0488 0.3268
Brugia malayi hypothetical protein 0.0876 0.1493 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0048
Entamoeba histolytica hypothetical protein 0.0074 0.0105 0.1072
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0039 0.039
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Leishmania major p-glycoprotein 0.0044 0.0052 0.052
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0014 0 0.0002
Plasmodium falciparum LCCL domain-containing protein 0.0063 0.0086 0.1246
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.0151 0.1011
Entamoeba histolytica hypothetical protein 0.0074 0.0105 0.1072
Echinococcus granulosus multidrug resistance protein 1 0.0044 0.0052 0.0221
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0154 0.0659
Brugia malayi Protein kinase domain containing protein 0.0015 0.0003 0.002
Leishmania major metacaspase, putative 0.0018 0.0007 0.0071
Echinococcus granulosus transcription factor btf3 0.0035 0.0037 0.0158
Echinococcus granulosus caspase 0.0018 0.0007 0.003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0111 0.0168 0.0718
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0154 0.0659
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.001 0.001
Echinococcus multilocularis cathepsin L 0.0038 0.0043 0.0182
Brugia malayi Cathepsin L-like precursor 0.005 0.0062 0.0418
Echinococcus multilocularis lysine specific demethylase 5A 0.0116 0.0178 0.076
Chlamydia trachomatis cysteine--tRNA ligase 0.0084 0.0123 0.1692
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0007 0.0073
Toxoplasma gondii histone lysine methyltransferase SET1 0.0109 0.0165 0.3271
Brugia malayi sodium-independent organic anion transporter family protein 0.0304 0.0503 0.3371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0052 0.053
Schistosoma mansoni multidrug resistance protein 0.0044 0.0052 0.0221
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0202
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0304 0.0503 0.2151
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0039 0.0039
Schistosoma mansoni steroid hormone receptor ad4bp 0.0025 0.002 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.012 0.1203
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.003 0.0202
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.003 0.013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Echinococcus multilocularis pol protein 0.1287 0.2205 0.9423
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0007 0.0071
Echinococcus granulosus multidrug resistance protein 1 0.0044 0.0052 0.0221
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0044 0.0052 0.0655
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0014 0 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0589 0.0997 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.004 0.0406
Schistosoma mansoni inositol monophosphatase 0.0037 0.004 0.0173
Leishmania major hypothetical protein, conserved 0.0031 0.003 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0 0.0001
Echinococcus granulosus multidrug resistance protein 1 0.0044 0.0052 0.0221
Trichomonas vaginalis glutaminase, putative 0.0274 0.0451 0.4611
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.003 0.013
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.001 0.0195
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0412 0.0689 0.0689
Brugia malayi hypothetical protein 0.0025 0.002 0.0135
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0082 0.0119 0.3997
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0074 0.0105 0.1074
Echinococcus multilocularis microtubule associated protein 2 0.1365 0.234 1
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0044 0.0052 0.052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0025 0.002 0.0136
Entamoeba histolytica cysteine proteinase 2 0.0038 0.0043 0.0436
Loa Loa (eye worm) cysteine protease 0.0074 0.0105 0.0703
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0038 0.0043 0.0428
Echinococcus granulosus muscleblind protein 0.0295 0.0488 0.2086
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0034 0.0034
Echinococcus granulosus cathepsin l1 0.0074 0.0105 0.0449
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0014 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0025 0.002 0.0136
Brugia malayi Pre-SET motif family protein 0.021 0.034 0.2274
Loa Loa (eye worm) hypothetical protein 0.0063 0.0086 0.0575
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.004 0.0406
Schistosoma mansoni hypothetical protein 0.0809 0.1377 0.5886
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.003 0.0302
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0008 0.0056
Echinococcus multilocularis pol protein 0.1287 0.2205 0.9423
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0025 0.002 0.0087
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.0052 0.1029
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0084 0.0123 0.0524
Mycobacterium leprae Conserved hypothetical protein 0.0019 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0018 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0105 0.1074
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0052 0.0221
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0202
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0082 0.0119 0.2362
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0007 0.024
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.004 0.0406
Entamoeba histolytica cysteine proteinase, putative 0.0074 0.0105 0.1074
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.0151 0.2998
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.001 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.002 0.0202
Mycobacterium tuberculosis Possible penicillin-binding protein 0.023 0.0375 0.0375
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.002 0.001 0.0343
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0018 0.018
Brugia malayi Cathepsin L-like precursor 0.0074 0.0105 0.0703
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0084 0.0123 0.123
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.002 0.0136
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Trypanosoma brucei metacaspase MCA2 0.0018 0.0007 0.0071
Leishmania major basic transcription factor 3a, putative 0.0035 0.0037 0.0372
Brugia malayi Cathepsin L-like precursor 0.0074 0.0105 0.0703
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0025 0.002 0.0136
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0286 0.2928
Trypanosoma cruzi metacaspase, putative 0.0018 0.0007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0039 0.0039
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0031 0.003 0.0599
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0084 0.0123 0.0123
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0018 0.0018
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.001 0.001
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0007 0.0141
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0018 0.0117
Schistosoma mansoni follistatin 0.0177 0.0284 0.1212
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0052 0.0221
Trypanosoma brucei NAD+ synthase, putative 0.0082 0.0119 0.1193
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0001 0.0009
Trichomonas vaginalis esterase, putative 0.0036 0.0039 0.0398
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0185 0.0297 0.0297
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0082 0.0119 0.0119
Echinococcus granulosus cysteinyl tRNA synthetase 0.0084 0.0123 0.0524
Brugia malayi cathepsin F-like cysteine proteinase 0.0025 0.0019 0.0127
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0135
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0048 0.006 0.0597
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0007 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0037 0.0379
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.001 0.001
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0039 0.0039
Giardia lamblia Cathepsin L-like protease 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Brugia malayi MAP kinase sur-1 0.0101 0.0151 0.1011
Onchocerca volvulus 0.0063 0.0086 0.0574
Trichomonas vaginalis DNA helicase recq, putative 0.0029 0.0026 0.027
Plasmodium vivax serine-repeat antigen (SERA) 0.0014 0 0.0005
Echinococcus granulosus jumonji domain containing 1A 0.0031 0.003 0.0129
Brugia malayi Papain family cysteine protease containing protein 0.0014 0 0.0001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.001 0.01
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0014 0 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0 0.0001
Onchocerca volvulus 0.0074 0.0105 0.0702
Echinococcus multilocularis multidrug resistance protein 1 0.0044 0.0052 0.0221
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Onchocerca volvulus 0.0304 0.0503 0.337
Leishmania major cathepsin L-like protease 0.0074 0.0105 0.1053
Trypanosoma cruzi cytochrome P450, putative 0.0048 0.006 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0037 0.0379
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0412 0.0689 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0039 0.026
Schistosoma mansoni phosphatidylserine receptor 0.0031 0.003 0.0129
Echinococcus granulosus cathepsin b 0.0014 0 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Loa Loa (eye worm) cytochrome P450 0.0019 0.001 0.0067
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0341
Brugia malayi Cathepsin L-like precursor 0.0074 0.0105 0.0703
Brugia malayi hypothetical protein 0.0041 0.0048 0.0321
Trypanosoma brucei cytochrome P450, putative 0.0048 0.006 0.0597
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.001 0.001
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.001 0.001
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0014 0 0.0005
Toxoplasma gondii cathepsin B 0.0014 0 0.0003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Echinococcus granulosus lysine specific demethylase 5A 0.012 0.0183 0.0784
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.002 0.0136
Loa Loa (eye worm) hypothetical protein 0.0876 0.1493 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0025 0.002 0.0136
Trypanosoma cruzi NAD+ synthase, putative 0.0082 0.0119 0.1193
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0389 0.3985
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Echinococcus multilocularis cpg binding protein 0.006 0.008 0.0344
Onchocerca volvulus 0.0177 0.0284 0.1899
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0014 0 0.0001
Trichomonas vaginalis taga, putative 0.0044 0.0052 0.053
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Echinococcus granulosus cysteine protease 0.0038 0.0043 0.0182
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.001 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.005 0.0062 0.0639
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0279 0.0459 0.4608
Brugia malayi sodium-independent organic anion transporter family protein 0.0304 0.0503 0.3371
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.001 0.001
Plasmodium falciparum cysteine--tRNA ligase 0.0084 0.0123 0.1779
Echinococcus granulosus cathepsin b 0.0014 0 0.0001
Plasmodium falciparum serine repeat antigen 5 0.0014 0 0.0002
Brugia malayi ecdysteroid receptor 0.0025 0.002 0.0136
Plasmodium vivax vivapain-2 0.0074 0.0105 0.3528
Giardia lamblia Hypothetical protein 0.0014 0 0.0001
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Trypanosoma cruzi cysteine peptidase, putative 0.0025 0.0019 0.019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0025 0.002 0.0087
Plasmodium falciparum serine repeat antigen 8 0.0014 0 0.0002
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.004 0.0414
Echinococcus granulosus cathepsin L 0.0038 0.0043 0.0182
Onchocerca volvulus 0.0304 0.0503 0.337
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0 0.0001
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0185 0.0297 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Brugia malayi sodium-independent organic anion transporter family protein 0.0304 0.0503 0.3371
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.001 0.001
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0014 0 0.0001
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0086 0.0367
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0177 0.0284 0.5635
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0007 0.0073
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0104 0.0445
Brugia malayi Melibiase family protein 0.0068 0.0095 0.0636
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0014 0 0.0001
Plasmodium falciparum serine repeat antigen 3 0.0014 0 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.002 0.0087
Onchocerca volvulus Bile acid receptor homolog 0.0025 0.002 0.0135
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0224
Echinococcus granulosus JmjC domain containing protein 4 0.0031 0.003 0.0129
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0009 0.0037
Loa Loa (eye worm) glutaminase 0.0274 0.0451 0.3018
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0039 0.0398
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.0151 0.1514
Brugia malayi Cytochrome P450 family protein 0.0019 0.001 0.0067
Giardia lamblia Cysteine protease 0.0014 0 0.0001
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.001 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0589 0.0997 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0039 0.0398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0086 0.0369
Schistosoma mansoni thyroid hormone receptor 0.0025 0.002 0.0087
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0001 0.0006
Onchocerca volvulus 0.0057 0.0075 0.05
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.0007 0.0048
Onchocerca volvulus 0.0074 0.0105 0.0702
Giardia lamblia Cysteine protease 0.0014 0 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.002 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.001 0.001
Brugia malayi Cathepsin L-like precursor 0.0074 0.0105 0.0703
Echinococcus granulosus lipoxygenase domain containing protein 0.0063 0.0086 0.0367
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0039 0.039
Schistosoma mansoni loxhd1 0.0063 0.0086 0.0367
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0052 0.053
Onchocerca volvulus Protein ultraspiracle homolog 0.0025 0.002 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.001 0.001
Mycobacterium ulcerans glutaminase 0.0274 0.0451 0.0451
Leishmania major cytochrome p450-like protein 0.0048 0.006 0.0597
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0424 0.4343
Trichomonas vaginalis conserved hypothetical protein 0.0014 0 0.0001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.024 0.0392 0.1674
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0037 0.1246
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0018 0.018
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.004 0.0587
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0018 0.0018
Schistosoma mansoni jumonji/arid domain-containing protein 0.012 0.0183 0.0784
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0014 0 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0086 0.0369
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0127
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0025 0.0019 0.0127
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.0387 0.1652
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0082 0.0119 0.0119
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.001 0.001
Echinococcus granulosus dnaJ subfamily B 0.0809 0.1377 0.5886
Entamoeba histolytica P-glycoprotein-2 0.0044 0.0052 0.053
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0185 0.0297 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0048 0.0205
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0101 0.0151 0.1011
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0043 0.0436
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0018 0.0018
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0003 0.0012
Echinococcus multilocularis geminin 0.017 0.027 0.1156
Loa Loa (eye worm) hypothetical protein 0.0074 0.0105 0.0703
Onchocerca volvulus Putative organic anion transporter 0.0304 0.0503 0.337
Echinococcus multilocularis cathepsin L cysteine protease 0.0074 0.0105 0.0449
Schistosoma mansoni hypothetical protein 0.017 0.027 0.1156
Schistosoma mansoni cathepsin S (C01 family) 0.0014 0 0.0001
Schistosoma mansoni hypothetical protein 0.0041 0.0048 0.0205
Giardia lamblia Cysteine protease 0.0014 0 0.0001
Onchocerca volvulus 0.0031 0.003 0.0202
Echinococcus granulosus phd:f box containing protein 0.0031 0.003 0.0129
Brugia malayi Muscleblind-like protein 0.0295 0.0488 0.3268
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0304 0.0503 0.2151
Trypanosoma cruzi metacaspase, putative 0.0018 0.0007 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0025 0.002 0.0136
Plasmodium falciparum serine repeat antigen 7 0.0014 0 0.0002
Schistosoma mansoni cathepsin C 0.0014 0 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0005 0.0005
Trichomonas vaginalis hypothetical protein 0.0185 0.0297 0.3043
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0151 0.1544
Loa Loa (eye worm) multidrug resistance protein 3 0.0044 0.0052 0.0347
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0116 0.0178 0.076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0033 0.0033 0.0143
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0001 0.0009
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0258 0.0424 0.425
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0025 0.002 0.0087
Echinococcus granulosus caspase 2 0.0059 0.0079 0.0336
Brugia malayi ABC transporter family protein 0.0044 0.0052 0.0347
Schistosoma mansoni hypothetical protein 0.0063 0.0086 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0007 0.0073
Echinococcus multilocularis caspase 8 0.0018 0.0007 0.003
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.0151 0.0645
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0187 0.0799
Mycobacterium ulcerans NAD synthetase 0.0082 0.0119 0.0119
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0001 0.0008
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0014 0 0.0001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0282 0.0465 0.0465
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.006 0.0402
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0007 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0014 0 0.0001
Brugia malayi cathepsin Z-like cysteine proteinase 0.0014 0 0.0001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0025 0.002 0.0087
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0031 0.003 0.0302
Echinococcus multilocularis cathepsin b 0.0014 0 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.003 0.013
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0025 0.002 0.0136
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0418
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.0151 0.0645
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0007 0.0073
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0052 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0 0.0001
Schistosoma mansoni cathepsin F (C01 family) 0.005 0.0062 0.0267
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0151 0.1514
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0084 0.0123 0.2435
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0103 0.0154 0.0659
Brugia malayi Cathepsin L-like precursor 0.005 0.0062 0.0418
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0048
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0007 0.0007
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0304 0.0503 0.3371
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0151 0.1544
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.004 0.0804
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0025 0.002 0.0087
Echinococcus multilocularis caspase 2 0.0059 0.0079 0.0336
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.5788 1 1
Entamoeba histolytica recQ family helicase, putative 0.0015 0.0003 0.0032
Entamoeba histolytica hypothetical protein 0.0074 0.0105 0.1072
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0009
Leishmania major cathepsin L-like protease 0.0283 0.0466 0.4676
Plasmodium vivax unspecified product 0.0038 0.0043 0.1433
Onchocerca volvulus Putative organic anion transporter 0.0304 0.0503 0.337
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0084 0.0123 0.0524
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.001 0.001
Plasmodium falciparum enoyl-acyl carrier reductase 0.0185 0.0297 0.4316
Echinococcus granulosus multidrug resistance protein 1 0.003 0.0029 0.0124
Brugia malayi hypothetical protein 0.0074 0.0105 0.0701
Toxoplasma gondii cathepsin CPC1 0.0014 0 0.0003
Toxoplasma gondii transporter, major facilitator family protein 0.0304 0.0503 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Trypanosoma brucei RNA helicase, putative 0.0101 0.0151 0.152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Echinococcus multilocularis dnaJ subfamily B 0.0809 0.1377 0.5886
Plasmodium falciparum serine repeat antigen 9 0.0014 0 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.002 0.0087
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0412 0.0689 0.0689
Brugia malayi Cathepsin L-like precursor 0.0074 0.0105 0.0703
Brugia malayi beta-lactamase family protein 0.0036 0.0039 0.026
Loa Loa (eye worm) beta-lactamase 0.0036 0.0039 0.026
Schistosoma mansoni coup transcription factor 0.0025 0.002 0.0087
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0177 0.0284 0.1899
Schistosoma mansoni jumonji domain containing protein 0.0031 0.003 0.0129
Onchocerca volvulus Cell death protein 3 homolog 0.0059 0.0079 0.0525
Entamoeba histolytica hypothetical protein 0.0074 0.0105 0.1072
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0002 0.0007
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.001 0.001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.001 0.001
Brugia malayi Papain family cysteine protease containing protein 0.0038 0.0043 0.0285
Echinococcus granulosus cpg binding protein 0.006 0.008 0.0344
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0084 0.0123 0.1779
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.003 0.013
Trypanosoma cruzi cysteine proteinase, putative 0.0038 0.0043 0.0428
Echinococcus granulosus bloom syndrome protein 0.0029 0.0026 0.0113
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0279 0.0459 0.4608
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0052 0.053
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0412 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.0304 0.0503 0.3371
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0203
Brugia malayi cytochrome P450 0.0019 0.001 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0005 0.0005
Echinococcus multilocularis muscleblind protein 0.0295 0.0488 0.2086
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0018 0.018
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0086 0.0578
Brugia malayi RNA binding protein 0.0063 0.0086 0.0578
Entamoeba histolytica cysteine protease, putative 0.0074 0.0105 0.1074
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0007 0.0073
Loa Loa (eye worm) cathepsin B 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Leishmania major cytochrome p450-like protein 0.0019 0.001 0.01
Schistosoma mansoni jumonji/arid domain-containing protein 0.012 0.0183 0.0784
Trichomonas vaginalis DNA helicase recq, putative 0.0015 0.0003 0.0032
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.001 0.001
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0424 0.2842
Onchocerca volvulus 0.0074 0.0105 0.0702
Schistosoma mansoni agrin 0.0177 0.0284 0.1212
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0084 0.0123 0.123
Echinococcus granulosus RUN 0.0063 0.0086 0.0367
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0014 0 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0043 0.0436
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0074 0.0105 0.0449
Onchocerca volvulus 0.0239 0.039 0.2609
Loa Loa (eye worm) fibroinase 0.0074 0.0105 0.0703
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0009 0.0059
Trypanosoma cruzi major cysteine proteinase, putative 0.0222 0.0361 0.3625
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0014 0 0.0001
Loa Loa (eye worm) inositol-1 0.0037 0.004 0.0271
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0044 0.0052 0.053
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0086 0.0369
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0014 0 0.0001
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0014 0 0.0005
Onchocerca volvulus 0.0074 0.0105 0.0702
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0038 0.0043 0.0182
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0036 0.0153
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.003 0.0603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0 0.0001
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.5788 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0043 0.0436
Plasmodium falciparum multidrug resistance protein 1 0.0044 0.0052 0.0752
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0124 0.0191 0.0817
Brugia malayi prostaglandin transporter 0.0304 0.0503 0.3371
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0101 0.0151 0.1518
Loa Loa (eye worm) doublecortin family protein 0.0063 0.0086 0.0575
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.001 0.001
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Plasmodium falciparum cysteine--tRNA ligase 0.0084 0.0123 0.1779
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0039 0.0039
Brugia malayi Cytochrome P450 family protein 0.0048 0.006 0.0398
Loa Loa (eye worm) hypothetical protein 0.0063 0.0086 0.0575
Plasmodium vivax serine-repeat antigen (SERA) 0.0014 0 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Loa Loa (eye worm) steroid hormone receptor 0.0025 0.002 0.0136
Trypanosoma cruzi cysteine peptidase, putative 0.0038 0.0043 0.0428
Trypanosoma brucei metacaspase 0.0018 0.0007 0.0071
Trypanosoma cruzi NAD+ synthase, putative 0.0082 0.0119 0.1193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0185 0.0297 0.4316
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0002 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.001 0.001
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0037 0.0372
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0101 0.0151 0.1011
Trichomonas vaginalis abcb9, putative 0.0044 0.0052 0.053
Leishmania major cathepsin L-like protease 0.0074 0.0105 0.1053
Plasmodium falciparum metacaspase-like protein 0.0018 0.0007 0.0103
Echinococcus multilocularis Ankyrin 0.0015 0.0002 0.0007
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0039 0.0166
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.002 0.0677
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0037 0.0379
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.001 0.001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.002 0.0087
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0007 0.003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0025 0.002 0.0136
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0018 0.0117
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.001 0.001
Echinococcus multilocularis caspase 0.0018 0.0007 0.003
Brugia malayi nuclear hormone receptor 0.0025 0.002 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Onchocerca volvulus 0.005 0.0062 0.0417
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0151 0.1514
Schistosoma mansoni multidrug resistance protein 0.0044 0.0052 0.0221
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0014 0 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0025 0.002 0.0136
Plasmodium falciparum serine repeat antigen 1 0.0014 0 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.0151 0.0645
Schistosoma mansoni retinoic acid receptor RXR 0.0124 0.0191 0.0817
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0412 0.0689 0.0689
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0025 0.002 0.0136
Schistosoma mansoni cpg binding protein 0.0057 0.0075 0.032
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.001 0.01
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0003 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0116 0.0178 0.076
Schistosoma mansoni hypothetical protein 0.017 0.027 0.1156
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0105 0.0703
Schistosoma mansoni netrin receptor unc5 0.0014 0.0001 0.0006
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0025 0.002 0.0087
Entamoeba histolytica P-glycoprotein-1 0.0044 0.0052 0.053
Schistosoma mansoni lipoxygenase 0.0126 0.0195 0.0832
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.006 0.0398
Brugia malayi cathepsin L-like cysteine proteinase 0.0014 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.001 0.001
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0014 0 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Loa Loa (eye worm) CYP4Cod1 0.0048 0.006 0.0398
Giardia lamblia Cysteinyl-tRNA synthetase 0.0084 0.0123 0.1254
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0052 0.0221
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0039 0.0039
Onchocerca volvulus Cathepsin F homolog 0.0074 0.0105 0.0702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0286 0.2928
Entamoeba histolytica cysteine protease, putative 0.0014 0 0.0001
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0014 0 0.0001
Brugia malayi cathepsin Z-like cysteine proteinase 0.0014 0 0.0001
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.0009
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0037 0.0538
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0018 0.0018
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0083 0.012 0.1203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0025 0.002 0.0136
Onchocerca volvulus 0.0304 0.0503 0.337
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0578 0.0977 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0048 0.0321
Toxoplasma gondii melibiase subfamily protein 0.0103 0.0154 0.3062
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0039 0.0166
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0086 0.0578
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0018 0.0018
Echinococcus multilocularis jumonji domain containing 1A 0.0031 0.003 0.0129
Brugia malayi Cytochrome P450 family protein 0.0048 0.006 0.0398
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.004 0.0414
Trypanosoma cruzi cysteine peptidase, putative 0.0283 0.0466 0.4676
Onchocerca volvulus 0.0044 0.0052 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Mycobacterium ulcerans GMP synthase 0.0033 0.0033 0.0033
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0018 0.0018
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0025 0.002 0.0087
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Trypanosoma cruzi cruzipain precursor, putative 0.0283 0.0466 0.4676
Leishmania major NAD synthase, putative 0.0082 0.0119 0.1193
Treponema pallidum fructose-bisphosphate aldolase 0.0578 0.0977 1
Mycobacterium ulcerans lipase LipD 0.0036 0.0039 0.0039
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.027 0.181
Brugia malayi TAR-binding protein 0.0063 0.0086 0.0578
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.001 0.001
Echinococcus granulosus arachidonate 5 lipoxygenase 0.024 0.0392 0.1674
Giardia lamblia Cathepsin L precursor 0.0014 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0025 0.002 0.0136
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0 0.0001
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.004 0.0173
Brugia malayi cathepsin F-like cysteine proteinase 0.0014 0 0.0001
Echinococcus multilocularis bloom syndrome protein 0.0029 0.0026 0.0113
Echinococcus granulosus FTZ F1 alpha 0.0025 0.002 0.0087
Trichomonas vaginalis abcb9, putative 0.0044 0.0052 0.053
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Loa Loa (eye worm) hypothetical protein 0.0145 0.0228 0.1527
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.0151 0.0645
Schistosoma mansoni hypothetical protein 0.0101 0.0151 0.0647
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0018 0.0117
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0037 0.0372
Brugia malayi steroid hormone receptor 0.0025 0.002 0.0136
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0018 0.0007 0.003
Entamoeba histolytica NAD synthetase, putative 0.0082 0.0119 0.1217
Entamoeba histolytica hypothetical protein 0.0035 0.0037 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.003 0.0202
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0025 0.002 0.0136
Schistosoma mansoni lipoxygenase 0.024 0.0392 0.1674
Onchocerca volvulus 0.0041 0.0048 0.032
Trichomonas vaginalis DNA helicase recq1, putative 0.0029 0.0026 0.027
Loa Loa (eye worm) hypothetical protein 0.0177 0.0284 0.1899
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.001 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.026
Echinococcus multilocularis pol protein 0.1287 0.2205 0.9423
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0174
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.004 0.0173
Giardia lamblia Cysteine protease 0.0014 0 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.004 0.004
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0084 0.0123 0.123
Brugia malayi Doublecortin family protein 0.0063 0.0086 0.0575
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0095 0.0971
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0003 0.0012
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0044 0.0052 0.053
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.026
Schistosoma mansoni protein phosphatase 2C 0.0031 0.003 0.0129
Schistosoma mansoni RAR-like nuclear receptor 0.0025 0.002 0.0087
Entamoeba histolytica P-glycoprotein-2 0.0044 0.0052 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0105 0.1074
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.001 0.001
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0007 0.0239
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0105 0.0448
Brugia malayi fibroinase precursor 0.0014 0 0.0001
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Loa Loa (eye worm) agrin synaptic family protein 0.0177 0.0284 0.1899
Loa Loa (eye worm) RecQ helicase 0.0029 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.026
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.002 0.0292
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.001 0.001
Plasmodium vivax multidomain scavenger receptor, putative 0.0063 0.0086 0.2887
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0033 0.0033 0.0335
Schistosoma mansoni thyroid hormone receptor 0.0025 0.002 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.027 0.2766
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0048
Entamoeba histolytica cysteine protease, putative 0.0014 0 0.0001
Onchocerca volvulus 0.0048 0.006 0.0402
Entamoeba histolytica P-glyco protein 6, putative 0.0044 0.0052 0.053
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0033 0.0033 0.0663
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0074 0.0105 0.0703
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0044 0.0052 0.0347
Entamoeba histolytica cysteine protease, putative 0.0014 0 0.0001
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.001 0.001
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0044 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.006 0.0398
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0025 0.0019 0.0127
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.001 0.001
Plasmodium vivax vivapain-3 0.0038 0.0043 0.1433
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0039 0.026
Brugia malayi Pre-SET motif family protein 0.0031 0.003 0.0203
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Toxoplasma gondii protease inhibitor PI2 0.0177 0.0284 0.5635
Trypanosoma cruzi metacaspase, putative 0.0018 0.0007 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0 0.0001
Onchocerca volvulus 0.0876 0.1493 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0578 0.0977 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0086 0.0369
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Schistosoma mansoni GMP synthetase 0.0033 0.0033 0.0143
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0052 0.053
Trypanosoma cruzi cysteine proteinase, putative 0.0038 0.0043 0.0428
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0082 0.0119 0.1217
Leishmania major hypothetical protein, conserved 0.0036 0.0039 0.039
Echinococcus granulosus geminin 0.017 0.027 0.1156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0043 0.0436
Entamoeba histolytica hypothetical protein 0.0014 0 0.0001
Plasmodium falciparum serine repeat antigen 2 0.0014 0 0.0002
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0178 0.1193
Schistosoma mansoni smdr2 0.0044 0.0052 0.0221
Toxoplasma gondii cathepsin CPC2 0.0014 0 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0005 0.0005
Loa Loa (eye worm) glutaminase 2 0.0274 0.0451 0.3018
Echinococcus multilocularis expressed protein 0.0177 0.0284 0.1212
Echinococcus granulosus cathepsin l1 0.005 0.0062 0.0267
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0039 0.0398
Brugia malayi CXXC zinc finger family protein 0.0057 0.0075 0.0501
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0177 0.0284 0.1899
Onchocerca volvulus 0.0074 0.0105 0.0702
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0048 0.0205
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0052 0.053
Entamoeba histolytica P-glycoprotein-5 0.0044 0.0052 0.053
Brugia malayi Bloom's syndrome protein homolog 0.0029 0.0026 0.0177
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.0127
Brugia malayi Cytochrome P450 family protein 0.0061 0.0083 0.0554
Brugia malayi jmjC domain containing protein 0.0031 0.003 0.0202
Loa Loa (eye worm) hypothetical protein 0.0044 0.0052 0.0347
Loa Loa (eye worm) hypothetical protein 0.0084 0.0123 0.0821
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0014 0 0.0005
Entamoeba histolytica cysteine proteinase 1, putative 0.0038 0.0043 0.0436
Echinococcus multilocularis Protein lozenge 0.011 0.0167 0.0712
Plasmodium vivax SET domain protein, putative 0.0031 0.003 0.102
Leishmania major cathepsin L-like protease 0.0283 0.0466 0.4676
Echinococcus granulosus tar DNA binding protein 0.0063 0.0086 0.0369
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0018 0.0018
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0282 0.0465 0.0465
Trypanosoma cruzi cysteine peptidase, putative 0.0283 0.0466 0.4676
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.001 0.001
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0014 0 0.0005
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0282 0.0465 0.0465
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.026
Toxoplasma gondii hypothetical protein 0.0095 0.0141 0.2801
Giardia lamblia Hypothetical protein 0.0014 0 0.0001
Brugia malayi multidrug resistance protein 3 0.0044 0.0052 0.0347
Brugia malayi secreted modular calcium-binding protein 1 0.0177 0.0284 0.1899
Brugia malayi cathepsin L-like precursor 0.005 0.0062 0.0418
Schistosoma mansoni polycystin 1-related 0.0063 0.0086 0.0367
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0185 0.0297 0.4256
Entamoeba histolytica cysteine protease, putative 0.0014 0 0.0001
Leishmania major hypothetical protein, conserved 0.0025 0.002 0.0202
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0018 0.0007 0.003
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0082 0.0119 0.1725
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0039 0.039
Brugia malayi hypothetical protein 0.0237 0.0387 0.2589
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0086 0.0369
Leishmania major cathepsin L-like protease 0.0074 0.0105 0.1053
Mycobacterium ulcerans hypothetical protein 0.031 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0418
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0025 0.002 0.0087
Echinococcus multilocularis ATP binding cassette sub family B 0.0043 0.0051 0.0218
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0037 0.0372
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.001 0.001
Echinococcus multilocularis transcription factor btf3 0.0035 0.0037 0.0158
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.002 0.0136
Schistosoma mansoni glutaminase 0.0274 0.0451 0.1926
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.001 0.001
Brugia malayi beta-NAC-like protein 0.0035 0.0037 0.0248
Onchocerca volvulus 0.0304 0.0503 0.337
Leishmania major mitochondrial DNA polymerase beta 0.0589 0.0997 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0116 0.0178 0.076
Onchocerca volvulus 0.0063 0.0086 0.0574
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0086 0.0367
Brugia malayi hypothetical protein 0.0304 0.0503 0.3371
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0185 0.0297 0.0297
Echinococcus granulosus cathepsin L cysteine protease 0.0038 0.0043 0.0182
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.001 0.0198
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0001 0.0006
Leishmania major cathepsin L-like protease 0.0074 0.0105 0.1053
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0044 0.0052 0.053
Schistosoma mansoni cpg binding protein 0.006 0.008 0.0344
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0007 0.0141
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Brugia malayi Cathepsin L-like precursor 0.0025 0.0019 0.0127
Schistosoma mansoni cathepsin F (C01 family) 0.0074 0.0105 0.0449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Plasmodium vivax cysteine--tRNA ligase, putative 0.0084 0.0123 0.4121
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0007 0.0073
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0279 0.0459 0.4608
Trypanosoma cruzi metacaspase, putative 0.0018 0.0007 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0062 0.0639
Brugia malayi hypothetical protein 0.0063 0.0086 0.0575
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0007 0.0104
Brugia malayi hypothetical protein 0.0063 0.0086 0.0575
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0033 0.0033 0.0143
Echinococcus multilocularis FTZ F1 alpha 0.0025 0.002 0.0087
Giardia lamblia Cathepsin L precursor 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0044 0.0052 0.0347
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Toxoplasma gondii preprocathepsin c precursor, putative 0.0014 0 0.0003
Loa Loa (eye worm) hypothetical protein 0.0177 0.0284 0.1899
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.001 0.001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0025 0.002 0.0087
Loa Loa (eye worm) hypothetical protein 0.0237 0.0387 0.2589
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0177 0.0284 0.5635
Loa Loa (eye worm) hypothetical protein 0.0177 0.0284 0.1899
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0025 0.002 0.0136
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0018 0.0018
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.0151 0.0645
Plasmodium vivax vivapain-2 0.0074 0.0105 0.3528
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0003 0.0031
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.001 0.001
Schistosoma mansoni rab6-interacting 0.0063 0.0086 0.0367
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0014 0 0.0001
Plasmodium vivax GMP synthetase, putative 0.0033 0.0033 0.1122
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.002 0.0202
Brugia malayi Death domain containing protein 0.0014 0.0001 0.0009
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.003 0.0029 0.0297
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0084 0.0123 0.1254
Plasmodium vivax multidrug resistance protein 1, putative 0.0044 0.0052 0.1741
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0084 0.0123 0.1254
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0007 0.0007
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.002 0.04
Brugia malayi SPARC precursor 0.0177 0.0284 0.1899
Brugia malayi cathepsin L precursor 0.0014 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.026
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0014 0 0.0001
Loa Loa (eye worm) runx1 0.011 0.0167 0.1116
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0039 0.1307
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0039 0.0039
Brugia malayi Steroid receptor seven-up type 2 0.0025 0.002 0.0136
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0086 0.0369
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0177 0.0284 0.5635
Schistosoma mansoni survival motor neuron protein 0.0048 0.006 0.0257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.0151 0.0645
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0 0.0001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0031 0.003 0.0302
Echinococcus granulosus microtubule associated protein 2 0.1365 0.234 1
Onchocerca volvulus 0.0074 0.0105 0.0702
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.0151 0.0645
Echinococcus granulosus Solute carrier organic anion transporter family 0.0304 0.0503 0.2151
Schistosoma mansoni microtubule-associated protein tau 0.1365 0.234 1
Echinococcus multilocularis follistatin 0.0177 0.0284 0.1212
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.0016 0.0068
Echinococcus multilocularis cathepsin b 0.0014 0 0.0001
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0044 0.0052 0.0221
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0185 0.0297 0.5909
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Echinococcus granulosus cathepsin l cysteine peptidase 0.0074 0.0105 0.0449
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0075 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0 0.0001
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0424 0.2842
Brugia malayi Cathepsin L-like precursor 0.0074 0.0105 0.0703
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0025 0.002 0.0136
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0033 0.0033 0.0335
Trypanosoma brucei metacaspase 5, putative 0.0018 0.0007 0.0071
Trypanosoma cruzi cysteine peptidase, putative 0.0283 0.0466 0.4676
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0086 0.0578
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0424 0.4343
Plasmodium falciparum metacaspase 1 0.0018 0.0007 0.0103
Toxoplasma gondii ABC1 family protein 0.0036 0.0039 0.0772
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.0183 0.1228
Plasmodium falciparum serine repeat antigen 6 0.0014 0 0.0002
Loa Loa (eye worm) RNA binding protein 0.0063 0.0086 0.0578
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0177 0.0284 0.1899
Plasmodium vivax unspecified product 0.0025 0.0019 0.0636
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0026 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0151 0.0645
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0031 0.003 0.0129
Brugia malayi photoreceptor-specific nuclear receptor 0.0025 0.002 0.0136
Schistosoma mansoni rab6-interacting 0.0063 0.0086 0.0367
Trypanosoma brucei protein kinase, putative 0.0101 0.0151 0.1514
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.0042
Echinococcus multilocularis thyroid hormone receptor alpha 0.0025 0.002 0.0087
Leishmania major cysteine peptidase A (CPA) 0.0074 0.0105 0.1053
Trypanosoma brucei metacaspase MCA3 0.0018 0.0007 0.0071
Giardia lamblia Cathepsin L precursor 0.0014 0 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.0387 0.1652
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0095 0.0406
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0014 0 0.0002
Echinococcus multilocularis pol protein 0.1287 0.2205 0.9423
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.0151 0.1514
Loa Loa (eye worm) hypothetical protein 0.0024 0.0018 0.0117
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.002 0.0087
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.0052 0.053
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0082 0.0119 0.0508
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0039 0.0039
Toxoplasma gondii Alpha-galactosidase 0.0015 0.0002 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.0151 0.0645
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.0151 0.0645
Brugia malayi jmjC domain containing protein 0.0031 0.003 0.0202
Schistosoma mansoni inositol monophosphatase 0.0037 0.004 0.0173
Brugia malayi jmjC domain containing protein 0.0116 0.0178 0.1191
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0177 0.0284 0.1899
Mycobacterium tuberculosis Conserved protein 0.0036 0.0039 0.0039
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0412 0.0689 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0074 0.0105 0.0703
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0003 0.0031
Giardia lamblia Cathepsin L-like protease 0.0014 0 0.0001
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.0151 0.1544
Brugia malayi Papain family cysteine protease containing protein 0.0014 0 0.0001
Echinococcus multilocularis Polycystic kidney disease protein 0.0063 0.0086 0.0367
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0014 0 0.0005
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.001 0.001
Loa Loa (eye worm) ctsf protein 0.0074 0.0105 0.0703
Schistosoma mansoni transcription factor btf3 0.0035 0.0037 0.0158
Giardia lamblia Fructose-bisphosphate aldolase 0.0578 0.0977 1
Leishmania major cytochrome p450-like protein 0.0019 0.001 0.01
Onchocerca volvulus 0.0074 0.0105 0.0702
Echinococcus granulosus death domain containing protein 0.0014 0.0001 0.0006
Schistosoma mansoni organic anion transporter 0.0304 0.0503 0.2151
Brugia malayi hypothetical protein 0.0304 0.0503 0.3371
Brugia malayi cathepsin B-like cysteine proteinase 0.0014 0 0.0001
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0014 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0025 0.002 0.0136
Trichomonas vaginalis ABC transporter, putative 0.0044 0.0052 0.053
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0074 0.0105 0.1523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0 0.0001
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0052 0.0221
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0039 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.005 0.0062 0.0639
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0074 0.0105 0.1074
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0083 0.012 0.1203
Echinococcus granulosus leucyl tRNA synthetase 0.0084 0.0123 0.0524
Brugia malayi GMP synthase 0.0033 0.0033 0.0224
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.001 0.001
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0038 0.0043 0.0428
Giardia lamblia Cathepsin L precursor 0.0014 0 0.0001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0044 0.0052 0.053
Giardia lamblia Cathepsin L precursor 0.0014 0 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0038 0.0043 0.0436
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0014 0 0.0001
Plasmodium vivax metacaspase 1, putative 0.0018 0.0007 0.0239
Loa Loa (eye worm) hypothetical protein 0.0014 0 0.0001
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.001 0.001
Brugia malayi hypothetical protein 0.0016 0.0005 0.0031
Echinococcus multilocularis multidrug resistance protein 1 0.0044 0.0052 0.0221
Onchocerca volvulus 0.0036 0.0039 0.0259
Brugia malayi jmjC domain containing protein 0.0031 0.003 0.0202
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0578 0.0977 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0025 0.002 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0018 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0151 0.1544
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0105 0.0448
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.001 0.01
Giardia lamblia Cathepsin B precursor 0.0014 0 0.0001
Giardia lamblia Cathepsin L precursor 0.0014 0 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0154 0.0659
Schistosoma mansoni cytochrome P450 0.0019 0.001 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0 0.0001
Toxoplasma gondii cathepsin CPL 0.0074 0.0105 0.2085
Entamoeba histolytica P-glycoprotein 5, putative 0.0044 0.0052 0.053
Echinococcus multilocularis lipoxygenase domain containing protein 0.0063 0.0086 0.0367
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.026
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0105 0.1053
Entamoeba histolytica cysteine protease, putative 0.0038 0.0043 0.0436
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0105 0.1074
Onchocerca volvulus Cathepsin L homolog 0.0074 0.0105 0.0702
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0043 0.0051 0.0218
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.0007 0.003
Echinococcus multilocularis agrin 0.0177 0.0284 0.1212
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0044 0.0052 0.0221
Echinococcus granulosus cathepsin L cysteine proteinase 0.0074 0.0105 0.0449
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0009 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.0466 0.4676
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0007 0.0071
Leishmania major cathepsin L-like protease 0.0283 0.0466 0.4676
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0003 0.0031
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0295 0.0488 0.3268
Onchocerca volvulus 0.0084 0.0123 0.082
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.003 0.0202
Onchocerca volvulus Cathepsin L homolog 0.0074 0.0105 0.0702
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0177 0.0284 0.5635
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0424 0.4343
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0424 0.4343
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.001 0.001
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0084 0.0123 0.0524
Echinococcus multilocularis JmjC domain containing protein 4 0.0031 0.003 0.0129
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0083 0.0554
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0136
Plasmodium falciparum cysteine proteinase falcipain 1 0.0038 0.0043 0.0618
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0037 0.0248

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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