Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | dual specificity testis specific protein kinase | 0.1605 | 0.6166 | 0.6166 |
Brugia malayi | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0438 | 0.1622 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.259 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | carboxylesterase 5A | 0.259 | 1 | 1 |
Onchocerca volvulus | 0.0021 | 0.0001 | 0.0005 | |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0438 | 0.1622 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | Microtubule-associated serine/threonine-protein kinase | 0.0021 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0438 | 0.1622 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.259 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.1605 | 0.6166 | 0.6166 |
Brugia malayi | hypothetical protein | 0.003 | 0.0036 | 0.0036 |
Echinococcus granulosus | acetylcholinesterase | 0.259 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.1605 | 0.6166 | 0.6166 |
Echinococcus granulosus | dual specificity testis-specific protein kinase | 0.1605 | 0.6166 | 0.6166 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Chlamydia trachomatis | tail-specific protease | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | MAGUK homolog | 0.0021 | 0.0001 | 0.0001 |
Echinococcus multilocularis | acetylcholinesterase | 0.259 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.259 | 1 | 1 |
Echinococcus multilocularis | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Echinococcus granulosus | peripheral plasma membrane protein CASK | 0.0021 | 0.0001 | 0.0001 |
Schistosoma mansoni | gliotactin | 0.0438 | 0.1622 | 0.1622 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0438 | 0.1622 | 0.5 |
Schistosoma mansoni | protein phosphatase 1 inhibitor potentiated by protein kinase C | 0.003 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.259 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | acetylcholinesterase | 0.259 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | neuroligin | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | PKC activated phosphatase 1 inhibitor | 0.003 | 0.0036 | 0.0036 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0036 | 0.0036 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.259 | 1 | 1 |
Echinococcus multilocularis | PKC activated phosphatase 1 inhibitor | 0.003 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | AGC/MAST/MAST protein kinase | 0.0021 | 0.0001 | 0.0001 |
Echinococcus granulosus | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Schistosoma mansoni | acetylcholinesterase | 0.0438 | 0.1622 | 0.1622 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Echinococcus granulosus | PDZ and LIM domain protein Zasp | 0.0022 | 0.0003 | 0.0003 |
Schistosoma mansoni | pdz and lim domain protein | 0.0022 | 0.0003 | 0.0003 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | microtubule associated serine:threonine protein | 0.0021 | 0.0001 | 0.0001 |
Echinococcus multilocularis | peripheral plasma membrane protein CASK | 0.0021 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0438 | 0.1622 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.259 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.259 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Onchocerca volvulus | 0.0438 | 0.1622 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | neuroligin | 0.0438 | 0.1622 | 0.1622 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0438 | 0.1622 | 0.5 |
Onchocerca volvulus | 0.003 | 0.0036 | 0.022 | |
Loa Loa (eye worm) | carboxylesterase | 0.0438 | 0.1622 | 0.1622 |
Brugia malayi | Carboxylesterase family protein | 0.0438 | 0.1622 | 0.1622 |
Loa Loa (eye worm) | hypothetical protein | 0.259 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.1622 | 0.1622 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0438 | 0.1622 | 0.1622 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0438 | 0.1622 | 0.1622 |
Schistosoma mansoni | lim domain | 0.0022 | 0.0003 | 0.0003 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.