Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | adenosylhomocysteinase | 0.1005 | 0.6029 | 0.6029 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.1624 | 1 | 1 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.1624 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.1624 | 1 | 0.5 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.1624 | 1 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.1624 | 1 | 0.5 |
Plasmodium falciparum | adenosylhomocysteinase | 0.1624 | 1 | 0.5 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.1624 | 1 | 1 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.1624 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1005 | 0.6029 | 0.6029 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.022 | 0.0995 | 0.0995 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.1624 | 1 | 0.5 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.1624 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.1624 | 1 | 1 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.1624 | 1 | 0.5 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1005 | 0.6029 | 0.6029 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1005 | 0.6029 | 0.6029 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.1624 | 1 | 0.5 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.1624 | 1 | 1 |
Echinococcus granulosus | adenosylhomocysteinase | 0.1624 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1624 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.1624 | 1 | 1 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.1624 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.