Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0202 | 0.1196 | 0.1211 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0202 | 0.1196 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.013 | 0.0532 | 0.3985 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0202 | 0.1196 | 0.1211 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0202 | 0.1196 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0202 | 0.1196 | 0.8958 |
Schistosoma mansoni | thyroid hormone receptor | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0202 | 0.1196 | 0.1211 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0202 | 0.1196 | 0.8958 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0202 | 0.1196 | 0.8958 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.013 | 0.0532 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.1156 | 1 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.013 | 0.0532 | 0.4448 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.0409 | 0.0414 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.0409 | 0.0414 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | nuclear receptor NHR-88 | 0.0202 | 0.1196 | 0.1211 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Brugia malayi | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Schistosoma mansoni | nuclear hormone receptor | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0202 | 0.1196 | 0.1211 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0202 | 0.1196 | 0.8958 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0202 | 0.1196 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0202 | 0.1196 | 0.1211 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1143 | 0.988 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0217 | 0.1335 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0346 | 0.2531 | 0.2562 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0202 | 0.1196 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.013 | 0.0532 | 0.0539 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0202 | 0.1196 | 0.8958 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0202 | 0.1196 | 0.1211 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0202 | 0.1196 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.013 | 0.0532 | 0.0539 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0202 | 0.1196 | 0.1211 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0202 | 0.1196 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0202 | 0.1196 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0202 | 0.1196 | 0.1211 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0202 | 0.1196 | 0.8958 |
Brugia malayi | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.0409 | 0.0414 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0202 | 0.1196 | 0.1211 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0202 | 0.1196 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0202 | 0.1196 | 0.8958 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0202 | 0.1196 | 0.1211 |
Onchocerca volvulus | 0.0202 | 0.1196 | 0.1211 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0202 | 0.1196 | 0.8958 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.013 | 0.0532 | 0.4448 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.013 | 0.0532 | 0.4448 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0202 | 0.1196 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0202 | 0.1196 | 0.8958 |
Schistosoma mansoni | coup transcription factor | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0202 | 0.1196 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0202 | 0.1196 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.1143 | 0.988 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0202 | 0.1196 | 1 |
Brugia malayi | nuclear receptor RXR | 0.013 | 0.0532 | 0.0539 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0202 | 0.1196 | 0.1211 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | steroid hormone receptor | 0.0346 | 0.2531 | 0.2562 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0202 | 0.1196 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0532 | 0.0539 |
Brugia malayi | ecdysteroid receptor | 0.1143 | 0.988 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0202 | 0.1196 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | nuclear hormone receptor | 0.0202 | 0.1196 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.1196 | 0.1211 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0202 | 0.1196 | 0.1211 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.