Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | DNA polymerase eta, putative | 0.0048 | 0.9701 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Echinococcus granulosus | dna polymerase eta | 0.0048 | 0.9701 | 0.9633 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0048 | 0.9701 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0034 | 0.5597 | 0.4775 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0048 | 0.9701 | 0.9633 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0034 | 0.5597 | 0.4775 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.1847 | 0.1904 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.1847 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.1847 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0048 | 0.9701 | 0.9633 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.1847 | 0.1904 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.1847 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.1847 | 0.5 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0034 | 0.5597 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.1847 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.1847 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.9701 | 0.9633 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.1847 | 0.1904 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0048 | 0.9701 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0048 | 0.9701 | 0.9633 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.