Detailed information for compound 812886

Basic information

Technical information
  • TDR Targets ID: 812886
  • Name: [diethoxyphosphoryl-(4-nitrophenyl)methyl] ca rbamate
  • MW: 332.246 | Formula: C12H17N2O7P
  • H donors: 1 H acceptors: 4 LogP: 0.98 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOP(=O)(C(c1ccc(cc1)[N+](=O)[O-])OC(=O)N)OCC
  • InChi: 1S/C12H17N2O7P/c1-3-19-22(18,20-4-2)11(21-12(13)15)9-5-7-10(8-6-9)14(16)17/h5-8,11H,3-4H2,1-2H3,(H2,13,15)
  • InChiKey: AZUCIFQBAURMGE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • carbamic acid [diethoxyphosphoryl-(4-nitrophenyl)methyl] ester
  • CBMicro_014761
  • BIM-0014721.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Nicastrin 0.0097 0.0287 0.097
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0474 0.1802 0.1802
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0164 0.0558 0.2036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0425 0.1602 0.1602
Entamoeba histolytica presenilin 1 peptidase, putative 0.0199 0.0697 1
Loa Loa (eye worm) gamma-secretase subunit pen-2 0.0187 0.0648 0.0648
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0134 0.0212
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0046 0.0081 1
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0046 0.0081 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0164 0.0558 0.2036
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.0387 0.1364
Leishmania major presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative 0.0199 0.0697 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0046 0.0081 0.1165
Brugia malayi gamma-secretase subunit aph-1 0.0474 0.1802 0.1802
Echinococcus multilocularis presenilin 0.0199 0.0697 0.2582
Loa Loa (eye worm) hypothetical protein 0.2517 1 1
Brugia malayi hypothetical protein 0.007 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0081
Brugia malayi SWIRM domain containing protein 0.0046 0.0081 0.0081
Schistosoma mansoni hypothetical protein 0.0122 0.0387 0.1226
Echinococcus multilocularis protoporphyrinogen oxidase 0.0046 0.0081 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0425 0.1602 0.1602
Echinococcus granulosus Nuclear hormone receptor HR96 0.0164 0.0558 0.2036
Schistosoma mansoni hypothetical protein 0.0048 0.0089 0.0032
Onchocerca volvulus 0.0164 0.0558 0.0481
Echinococcus granulosus ecdysone induced protein 78C 0.0425 0.1602 0.6149
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0199 0.0697 1
Echinococcus granulosus nuclear receptor nhr 48 0.0164 0.0558 0.2036
Toxoplasma gondii histone lysine-specific demethylase 0.0046 0.0081 0.4563
Brugia malayi Presenilin family protein 0.0199 0.0697 0.0697
Brugia malayi nuclear receptor NHR-88 0.0425 0.1602 0.1602
Echinococcus multilocularis FTZ F1 alpha 0.0425 0.1602 0.6149
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0164 0.0558 0.0481
Brugia malayi nuclear hormone receptor 0.0425 0.1602 0.1602
Trypanosoma cruzi UDP-galactopyranose mutase 0.0046 0.0081 0.1165
Schistosoma mansoni hypothetical protein 0.0048 0.0089 0.0032
Trypanosoma brucei presenilin-like aspartic peptidase, putative 0.0199 0.0697 1
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Trypanosoma cruzi Aph-1 protein, putative 0.0185 0.064 0.9187
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0425 0.1602 0.6149
Echinococcus multilocularis presenilin enhancer 2 0.0187 0.0648 0.2389
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0164 0.0558 0.2036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0425 0.1602 0.1602
Onchocerca volvulus 0.0425 0.1602 0.1534
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0425 0.1602 0.1602
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0425 0.1602 0.6149
Echinococcus multilocularis nuclear receptor nhr 48 0.0164 0.0558 0.2036
Brugia malayi nuclear receptor NHR-67 0.0164 0.0558 0.0558
Brugia malayi orphan nuclear receptor NR2E1 0.0164 0.0558 0.0558
Brugia malayi hypothetical protein 0.0164 0.0558 0.0558
Schistosoma mansoni hypothetical protein 0.0103 0.0311 0.0918
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0164 0.0558 0.2036
Mycobacterium ulcerans short chain dehydrogenase 0.1172 0.4601 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Schistosoma mansoni nuclear receptor nhr-48 0.0164 0.0558 0.1909
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0425 0.1602 0.6149
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0164 0.0558 0.2036
Brugia malayi hypothetical protein 0.026 0.0942 0.0942
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0647 0.2496 0.5343
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0425 0.1602 0.6087
Schistosoma mansoni hypothetical protein 0.0097 0.0287 0.0825
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0425 0.1602 0.1602
Brugia malayi Nuclear hormone receptor E75 0.0164 0.0558 0.0558
Echinococcus granulosus thyroid hormone receptor alpha 0.0454 0.1719 0.661
Schistosoma mansoni nuclear hormone receptor 0.0164 0.0558 0.1909
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0089 0.0189
Brugia malayi Presenilin spe-4 0.007 0.0178 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0425 0.1602 0.1602
Loa Loa (eye worm) nuclear hormone receptor 0.0164 0.0558 0.0558
Brugia malayi hypothetical protein 0.0097 0.0287 0.0287
Echinococcus multilocularis ecdysone induced protein 78C 0.0425 0.1602 0.6149
Schistosoma mansoni hypothetical protein 0.0048 0.0089 0.0032
Loa Loa (eye worm) steroid hormone receptor 0.0714 0.2763 0.2763
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0311 0.0311
Schistosoma mansoni thyroid hormone receptor 0.0547 0.2092 0.8045
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0199 0.0697 1
Brugia malayi Nuclear hormone receptor-like 1 0.026 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.026 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0081
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0164 0.0558 0.0558
Schistosoma mansoni nuclear receptor 0.0164 0.0558 0.1909
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0425 0.1602 0.1602
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Brugia malayi nuclear receptor NHR-88 0.0164 0.0558 0.0558
Brugia malayi Nuclear hormone receptor E75 0.0164 0.0558 0.0558
Brugia malayi photoreceptor-specific nuclear receptor 0.0425 0.1602 0.1602
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0046 0.0081 0.0157
Schistosoma mansoni nuclear receptor 0.0164 0.0558 0.1909
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0089 0.0189
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.026 0.0941 0.3545
Loa Loa (eye worm) nuclear receptor NHR-67 0.0164 0.0558 0.0558
Schistosoma mansoni RAR-like nuclear receptor 0.0425 0.1602 0.6087
Brugia malayi amine oxidase, flavin-containing family protein 0.0046 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0081
Brugia malayi Presenilin spe-4 0.007 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0357 0.1329 0.1329
Loa Loa (eye worm) hypothetical protein 0.026 0.0942 0.0942
Echinococcus granulosus Nuclear hormone receptor HR96 0.0164 0.0558 0.2036
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0425 0.1602 0.1602
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0425 0.1602 0.6087
Trypanosoma cruzi Nicastrin, putative 0.0036 0.0041 0.0591
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.026 0.0942 0.3549
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0425 0.1602 0.6149
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0046 0.0081 0.5
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.026 0.0942 0.3446
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0081 1
Mycobacterium tuberculosis Probable oxidoreductase 0.1172 0.4601 1
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0134 0.7545
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0425 0.1602 0.1602
Trypanosoma brucei Aph-1 protein, putative 0.0185 0.064 0.9187
Chlamydia trachomatis protoporphyrinogen oxidase 0.0046 0.0081 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0425 0.1602 0.1602
Brugia malayi tailless protein 0.0164 0.0558 0.0558
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0134 0.0117
Schistosoma mansoni steroid hormone receptor ad4bp 0.0425 0.1602 0.6087
Echinococcus granulosus presenilin 0.0199 0.0697 0.2582
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0081
Trypanosoma brucei Presenilin enhancer-2 subunit of gamma secretase, putative 0.0056 0.0124 0.1776
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0425 0.1602 0.6149
Brugia malayi conserved hypotetical protein 0.0164 0.0558 0.0558
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0081 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0425 0.1602 0.1602
Schistosoma mansoni microtubule-associated protein tau 0.0668 0.258 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0425 0.1602 0.1602
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.015 0.0502 0.0502
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0134 0.1926
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0425 0.1602 0.6149
Echinococcus granulosus microtubule associated protein 2 0.0668 0.258 1
Echinococcus granulosus gamma secretase subunit aph 1 0.0474 0.1802 0.6935
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0164 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0134 0.0117
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Brugia malayi hypothetical protein 0.026 0.0942 0.0942
Schistosoma mansoni thyroid hormone receptor 0.0547 0.2092 0.8045
Loa Loa (eye worm) pigment dispersing factor receptor c 0.015 0.0502 0.0502
Echinococcus granulosus lysine specific histone demethylase 1A 0.0046 0.0081 0.0157
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.026 0.0942 0.0942
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0134 0.0117
Brugia malayi hypothetical protein 0.0164 0.0558 0.0558
Brugia malayi Calcitonin receptor-like protein seb-1 0.015 0.0502 0.0502
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0425 0.1602 0.6087
Brugia malayi nuclear hormone receptor 0.0164 0.0558 0.0558
Schistosoma mansoni hypothetical protein 0.0048 0.0089 0.0032
Trypanosoma cruzi presenilin-like aspartic peptidase, putative 0.0199 0.0697 1
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0199 0.0697 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0089 0.0089
Schistosoma mansoni nuclear hormone receptor 0.0425 0.1602 0.6087
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0425 0.1602 0.1602
Loa Loa (eye worm) hypothetical protein 0.0048 0.0089 0.0089
Trypanosoma cruzi Aph-1 protein, putative 0.0185 0.064 0.9187
Plasmodium falciparum protoporphyrinogen oxidase 0.0046 0.0081 1
Brugia malayi nuclear receptor RXR 0.026 0.0942 0.0942
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.026 0.0942 0.3549
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0425 0.1602 0.6149
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Trichomonas vaginalis Clan AD, family A22, presenilin-like aspartic peptidase 0.0199 0.0697 1
Echinococcus granulosus Nicastrin 0.0097 0.0287 0.097
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0089 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0425 0.1602 0.1602
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0134 0.0366
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0164 0.0558 0.0481
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0046 0.0081 0.4563
Loa Loa (eye worm) DR-78 0.0164 0.0558 0.0558
Leishmania major hypothetical protein, conserved 0.0056 0.0124 0.1776
Toxoplasma gondii hypothetical protein 0.007 0.0178 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0164 0.0558 0.1909
Brugia malayi hypothetical protein 0.007 0.0178 0.0178
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0602 0.2313 0.4938
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0425 0.1602 0.6149
Echinococcus multilocularis gamma secretase subunit aph 1 0.0474 0.1802 0.6935
Brugia malayi steroid hormone receptor 0.0714 0.2763 0.2763
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Brugia malayi Nuclear hormone receptor-like 1 0.0425 0.1602 0.1602
Trypanosoma brucei Nicastrin, putative 0.0036 0.0041 0.0591
Brugia malayi ecdysone receptor 0.0164 0.0558 0.0558
Echinococcus granulosus retinoic acid receptor rxr beta a 0.052 0.1985 0.7658
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0425 0.1602 0.1602
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0425 0.1602 0.1602
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0046 0.0081 1
Brugia malayi nuclear receptor RXR 0.0164 0.0558 0.0558
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0425 0.1602 0.1602
Brugia malayi MH2 domain containing protein 0.0244 0.0879 0.0879
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.0879 0.0879
Brugia malayi hypothetical protein 0.0046 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Loa Loa (eye worm) hypothetical protein 0.0097 0.0287 0.0287
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0425 0.1602 0.6149
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0134 0.0212
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0357 0.1329 0.1258
Echinococcus multilocularis 0.0046 0.0081 0.0157
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Trypanosoma cruzi Nicastrin, putative 0.0036 0.0041 0.0591
Schistosoma mansoni nuclear hormone receptor 0.0164 0.0558 0.1909
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0046 0.0081 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0425 0.1602 0.1602
Brugia malayi hypothetical protein 0.0097 0.0287 0.0287
Echinococcus multilocularis Nicastrin 0.0097 0.0287 0.097
Toxoplasma gondii hypothetical protein 0.0056 0.0124 0.6956
Loa Loa (eye worm) hypothetical protein 0.026 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Brugia malayi Nuclear hormone receptor-like 1 0.026 0.0942 0.0942
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0134 0.0117
Brugia malayi gamma-secretase subunit pen-2 0.0187 0.0648 0.0648
Brugia malayi N-terminal motif family protein 0.0357 0.1329 0.1329
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0081
Schistosoma mansoni subfamily A22A unassigned peptidase (A22 family) 0.0199 0.0697 0.2463
Onchocerca volvulus Protein ultraspiracle homolog 0.0425 0.1602 0.1534
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0164 0.0558 0.2036
Brugia malayi nuclear hormone receptor family member odr-7 0.0164 0.0558 0.0558
Echinococcus granulosus FTZ F1 alpha 0.0425 0.1602 0.6149
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0425 0.1602 0.6149
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0089 0.0089
Leishmania major UDP-galactopyranose mutase 0.0046 0.0081 0.1165
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0425 0.1602 0.6087
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0425 0.1602 0.1602
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0089 0.0089
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0425 0.1602 0.6149
Schistosoma mansoni retinoid-x-receptor (RXR) 0.026 0.0942 0.3446
Loa Loa (eye worm) hypothetical protein 0.0425 0.1602 0.1602
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0647 0.2496 0.5343
Brugia malayi Presenilin spe-4 0.007 0.0178 0.0178
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0164 0.0558 0.1909
Brugia malayi nuclear hormone receptor family member nhr-6 0.0164 0.0558 0.0558
Echinococcus multilocularis microtubule associated protein 2 0.0668 0.258 1
Loa Loa (eye worm) hypothetical protein 0.026 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.0103 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.015 0.0502 0.0502
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0425 0.1602 0.6087
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0089 0.0189
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0134 0.0366
Echinococcus granulosus GPCR family 2 0.0048 0.0089 0.0189
Schistosoma mansoni zinc finger protein 0.0164 0.0558 0.1909
Echinococcus granulosus lysine specific histone demethylase 1A 0.0046 0.0081 0.0157
Onchocerca volvulus 0.0164 0.0558 0.0481
Echinococcus multilocularis thyroid hormone receptor alpha 0.0547 0.2092 0.8076
Brugia malayi Presenilin-like protein At2g29900 0.007 0.0178 0.0178
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.0879 0.0879
Echinococcus granulosus presenilin enhancer 2 0.0187 0.0648 0.2389
Schistosoma mansoni gamma-secretase subunit aph-1 0.0474 0.1802 0.6886
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0425 0.1602 0.1602
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0425 0.1602 0.6087
Loa Loa (eye worm) hypothetical protein 0.026 0.0942 0.0942
Loa Loa (eye worm) presenilin spe-4 0.007 0.0178 0.0178
Onchocerca volvulus Bile acid receptor homolog 0.2517 1 1
Brugia malayi Steroid receptor seven-up type 2 0.0425 0.1602 0.1602
Echinococcus multilocularis GPCR, family 2 0.0048 0.0089 0.0189
Loa Loa (eye worm) hypothetical protein 0.0164 0.0558 0.0558
Brugia malayi hypothetical protein 0.007 0.0178 0.0178
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.0387 0.1364
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0425 0.1602 0.6149
Schistosoma mansoni coup transcription factor 0.0425 0.1602 0.6087
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0425 0.1602 0.1534
Schistosoma mansoni retinoic acid receptor RXR 0.052 0.1985 0.762
Loa Loa (eye worm) hypothetical protein 0.0046 0.0081 0.0081

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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