Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hexokinase type 2 | 0.4374 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1391 | 0.3081 | 0.3081 |
Onchocerca volvulus | 0.4374 | 1 | 1 | |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1146 | 0.2513 | 0.2513 |
Trypanosoma brucei | hexokinase | 0.4374 | 1 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1146 | 0.2513 | 0.2513 |
Brugia malayi | Hexokinase family protein | 0.4374 | 1 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | hexokinase | 0.4374 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.4374 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1391 | 0.3081 | 0.3081 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0086 | 0.0054 | 0.0054 |
Onchocerca volvulus | 0.4374 | 1 | 1 | |
Loa Loa (eye worm) | hexokinase | 0.1353 | 0.2995 | 0.2995 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0054 | 0.0054 |
Plasmodium falciparum | hexokinase | 0.4374 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.4374 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.4374 | 1 | 1 |
Onchocerca volvulus | 0.2744 | 0.622 | 0.622 | |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0086 | 0.0054 | 0.0054 |
Onchocerca volvulus | 0.4374 | 1 | 1 | |
Brugia malayi | hexokinase type II | 0.1391 | 0.3081 | 0.3081 |
Treponema pallidum | hexokinase (hxk) | 0.4374 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.4374 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.1353 | 0.2995 | 0.2995 |
Onchocerca volvulus | Hexokinase homolog | 0.2744 | 0.622 | 0.622 |
Schistosoma mansoni | hexokinase | 0.4374 | 1 | 1 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0086 | 0.0054 | 0.0054 |
Echinococcus multilocularis | hexokinase | 0.4374 | 1 | 1 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Trypanosoma brucei | hexokinase, putative | 0.4374 | 1 | 0.5 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.2983 | 0.6775 | 0.6775 |
Loa Loa (eye worm) | hexokinase | 0.2744 | 0.622 | 0.622 |
Echinococcus granulosus | hexokinase | 0.4374 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.4374 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.4374 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.4374 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.4374 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.4374 | 1 | 0.5 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0086 | 0.0054 | 0.0054 |
Plasmodium vivax | hexokinase, putative | 0.4374 | 1 | 0.5 |
Loa Loa (eye worm) | calcium channel | 0.0086 | 0.0054 | 0.0054 |
Leishmania major | hexokinase, putative | 0.4374 | 1 | 0.5 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0086 | 0.0054 | 0.0054 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | hexokinase | 0.4374 | 1 | 1 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0086 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hexokinase type II | 0.4374 | 1 | 1 |
Entamoeba histolytica | hexokinase 2 | 0.4374 | 1 | 1 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0086 | 0.0054 | 0.0054 |
Brugia malayi | Hexokinase family protein | 0.2744 | 0.622 | 0.622 |
Schistosoma mansoni | voltage-gated cation channel | 0.0086 | 0.0054 | 0.0054 |
Echinococcus granulosus | hexokinase type 2 | 0.4374 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.4374 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.