Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | chromobox protein | 0.0137 | 0.3638 | 0.2766 |
Echinococcus multilocularis | geminin | 0.0165 | 0.4952 | 0.2066 |
Brugia malayi | hypothetical protein | 0.0086 | 0.1206 | 0.0456 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0272 | 1 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0077 | 0.0786 | 0.7399 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.4952 | 0.426 |
Schistosoma mansoni | chromobox protein | 0.0137 | 0.3638 | 0.2766 |
Trichomonas vaginalis | chromobox protein, putative | 0.0083 | 0.1062 | 0.0969 |
Echinococcus multilocularis | acetylcholinesterase | 0.0272 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0272 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0165 | 0.4952 | 0.2066 |
Echinococcus multilocularis | acetylcholinesterase | 0.0272 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0786 | 0.0786 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0272 | 1 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0137 | 0.3638 | 0.3638 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.7982 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1206 | 0.1206 |
Brugia malayi | Carboxylesterase family protein | 0.0272 | 1 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0083 | 0.1062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1206 | 0.1206 |
Trichomonas vaginalis | chromobox protein, putative | 0.0137 | 0.3638 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.4952 | 0.426 |
Loa Loa (eye worm) | carboxylesterase | 0.0272 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0272 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0272 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0137 | 0.3638 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0137 | 0.3638 | 0.3096 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0272 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0083 | 0.1062 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.