Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0035 | 0.4775 | 0.4775 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0041 | 0.6924 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.6924 | 0.6924 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.6924 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0041 | 0.6924 | 0.6924 |
Loa Loa (eye worm) | inositol-1 | 0.0041 | 0.6924 | 0.6924 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0037 | 0.5404 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0041 | 0.6924 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.6924 | 0.6924 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0041 | 0.6924 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0041 | 0.6924 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.005 | 1 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.6924 | 0.6924 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.005 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.005 | 1 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0041 | 0.6924 | 0.6924 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.005 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0035 | 0.4775 | 0.4775 |
Schistosoma mansoni | DNA polymerase eta | 0.005 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0041 | 0.6924 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0041 | 0.6924 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.6924 | 0.6924 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0041 | 0.6924 | 0.6924 |
Echinococcus multilocularis | dna polymerase eta | 0.005 | 1 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0041 | 0.6924 | 0.6924 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0037 | 0.5404 | 0.5 |
Brugia malayi | Inositol-1 | 0.0041 | 0.6924 | 0.6924 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.