Detailed information for compound 81587

Basic information

Technical information
  • TDR Targets ID: 81587
  • Name: 1-benzyl-1-[3-[benzyl(tert-butylcarbamoyl)ami no]-2-hydroxypropyl]-3-tert-butylurea
  • MW: 468.632 | Formula: C27H40N4O3
  • H donors: 3 H acceptors: 3 LogP: 3.22 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(CN(C(=O)NC(C)(C)C)Cc1ccccc1)CN(C(=O)NC(C)(C)C)Cc1ccccc1
  • InChi: 1S/C27H40N4O3/c1-26(2,3)28-24(33)30(17-21-13-9-7-10-14-21)19-23(32)20-31(25(34)29-27(4,5)6)18-22-15-11-8-12-16-22/h7-16,23,32H,17-20H2,1-6H3,(H,28,33)(H,29,34)
  • InChiKey: DFQJKQKFAYTKKW-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-benzyl-1-[3-[benzyl(tert-butylcarbamoyl)amino]-2-hydroxy-propyl]-3-tert-butyl-urea
  • 1-benzyl-1-[3-[benzyl-[(tert-butylamino)-oxomethyl]amino]-2-hydroxypropyl]-3-tert-butylurea
  • 3-tert-butyl-1-[3-[tert-butylcarbamoyl(phenylmethyl)amino]-2-hydroxy-propyl]-1-(phenylmethyl)urea
  • 3-tert-butyl-1-[3-(tert-butylcarbamoyl-(phenylmethyl)amino)-2-hydroxypropyl]-1-(phenylmethyl)urea
  • 3-tert-butyl-1-[3-(tert-butylcarbamoyl-(phenylmethyl)amino)-2-hydroxy-propyl]-1-(phenylmethyl)urea
  • 3-tert-butyl-1-[3-[[(tert-butylamino)-oxomethyl]-(phenylmethyl)amino]-2-hydroxypropyl]-1-(phenylmethyl)urea
  • 1-(benzyl)-1-[3-(benzyl-(tert-butylcarbamoyl)amino)-2-hydroxy-propyl]-3-tert-butyl-urea
  • AIDS-006541
  • AIDS006541
  • N,N-(2-Hydroxy-1,3-propanediyl)bis[N-benzyl-N'-(1,1-dimethylethyl)urea]

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0021 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0188 0.1879
Onchocerca volvulus 0.0056 0.0191 0.1825
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0091 0.0228
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0019 0.0304
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0098 0.0247
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0084 0.0379
Schistosoma mansoni cpg binding protein 0.0028 0.0065 0.0162
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0169 0.0288
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0091 0.0228
Trichomonas vaginalis C-MYB, putative 0.0061 0.0214 0.2143
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Echinococcus granulosus cation transporting ATPase 13A3 0.0026 0.0055 0.0139
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0176 0.2803
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0055 0.0914
Echinococcus granulosus cathepsin b 0.0018 0.0019 0.0048
Trypanosoma brucei DNA polymerase eta, putative 0.0171 0.0717 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0046 0.0648
Mycobacterium tuberculosis Probable dehydrogenase 0.0347 0.1518 0.2119
Loa Loa (eye worm) hypothetical protein 0.0089 0.0342 0.135
Plasmodium vivax glutathione reductase, putative 0.0152 0.063 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0484 0.1909
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0394 0.099
Leishmania major trypanothione reductase 0.0152 0.063 0.8782
Echinococcus granulosus dnaJ subfamily B 0.0401 0.1765 0.4433
Brugia malayi Cathepsin L-like precursor 0.0034 0.0092 0.0413
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0004 0.0009
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0019 0.0075
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0035 0.0159
Echinococcus granulosus cpg binding protein 0.003 0.0072 0.0181
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0176 0.0301
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0019 0.0317
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0019 0.0304
Schistosoma mansoni smad 0.0026 0.0057 0.0142
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0026 0.0055 0.0077
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0176 0.0696
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0007 0.0007
Brugia malayi hypothetical protein 0.0019 0.0024 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0019 0.0033
Leishmania major DNA polymerase eta, putative 0.0091 0.035 0.4889
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0164 0.028
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0497 0.6933
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0069 0.0253 0.3524
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0101 0.0173
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0057 0.0224
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0092 0.023
Brugia malayi Cathepsin L-like precursor 0.0022 0.0035 0.0159
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0622 0.2773 0.2773
Trypanosoma brucei hypothetical protein, conserved 0.0069 0.0253 0.3524
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0164 0.0647
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0117 0.0471 0.1698
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Onchocerca volvulus 0.0056 0.0191 0.1825
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0055 0.0522
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0069 0.0253 0.3524
Plasmodium vivax calcium-transporting ATPase, putative 0.0117 0.0471 0.748
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0019 0.0086
Loa Loa (eye worm) fibroinase 0.0056 0.0191 0.0752
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0065 0.0163
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0036 0.0101 0.0172
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0026 0.0055 0.0249
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0098 0.0981
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0164 0.0412
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Brugia malayi Na,K-ATPase alpha subunit 0.0083 0.0313 0.1412
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0046 0.0147 0.243
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0096
Trichomonas vaginalis cation-transporting ATPase, putative 0.0117 0.0471 0.4717
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0077
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0046 0.0465
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0394 0.099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Loa Loa (eye worm) hypothetical protein 0.005 0.0163 0.0643
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0019 0.0304
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0035 0.0159
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.3524
Giardia lamblia Hypothetical protein 0.0018 0.0019 0.0075
Loa Loa (eye worm) pax transcription factor protein 2 0.0243 0.1045 0.4123
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0012 0.002
Brugia malayi Pre-SET motif family protein 0.003 0.0073 0.0327
Mycobacterium tuberculosis Conserved hypothetical protein 0.0116 0.0468 0.0653
Echinococcus multilocularis lamin dm0 0.0026 0.0057 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0612 0.1044
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0332 0.4633
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0101 0.0365
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0093 0.0359 0.1295
Echinococcus granulosus calcium transporting atpase 0.0101 0.0396 0.0993
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0447
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0176 0.0176
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0076 0.0284 0.0713
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0621
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0118 0.0202
Echinococcus multilocularis protein patched 0.0041 0.0125 0.0314
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.087 0.3431
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0191 0.1911
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Onchocerca volvulus 0.0092 0.0358 0.3422
Entamoeba histolytica cysteine protease, putative 0.0056 0.0191 0.3158
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Giardia lamblia Cathepsin L-like protease 0.0018 0.0019 0.0075
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0074 0.0267
Brugia malayi intermediate filament protein 0.0026 0.0057 0.0256
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.1004 0.396
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0169 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0118 0.1648
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0169 0.2677
Schistosoma mansoni cation-transporting ATPase 0.0026 0.0055 0.0139
Trypanosoma cruzi DNA polymerase eta, putative 0.0091 0.035 0.0598
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0024 0.0096
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0026 0.0055 0.0077
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0176 0.2803
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) MH2 domain-containing protein 0.0387 0.1702 0.6713
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0137 0.0344
Loa Loa (eye worm) hypothetical protein 0.0117 0.0471 0.1858
Brugia malayi Pax transcription factor protein 2 0.0243 0.1045 0.471
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0096 0.1343
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0996
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0069 0.0253 0.0634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0084
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.0091 0.0328
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0622 0.2773 0.3872
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0019 0.0086
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0057 0.0223
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2206 1 1
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0021 0.0054
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0308 0.0773
Giardia lamblia GTOR 0.0044 0.0137 0.0541
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0665 0.1669
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0069 0.0253 0.1138
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0214 0.0536
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Loa Loa (eye worm) hypothetical protein 0.0032 0.0084 0.0331
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.091
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0012
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0117 0.0471 0.1182
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0069 0.0253 0.1138
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Trypanosoma brucei unspecified product 0.0136 0.0557 0.7769
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0012 0.002
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0169 0.0608
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0026 0.0055 0.0055
Trypanosoma cruzi cruzipain precursor, putative 0.1298 0.5856 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0073 0.0182
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Brugia malayi RNA binding protein 0.0068 0.0245 0.1104
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0191 0.1825
Echinococcus multilocularis tumor protein p63 0.0331 0.1447 0.3634
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Toxoplasma gondii thioredoxin reductase 0.0152 0.063 0.227
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0098 0.1621
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Loa Loa (eye worm) hypothetical protein 0.0139 0.057 0.225
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0021 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.022 0.3069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.091
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.1504
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0394 0.099
Leishmania major proton motive ATPase, putative 0.0026 0.0055 0.0771
Echinococcus granulosus X box binding protein 1 0.0282 0.1225 0.3075
Loa Loa (eye worm) RecQ helicase 0.0045 0.0143 0.0562
Leishmania major hypothetical protein, conserved 0.0069 0.0253 0.3524
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi MH1 domain containing protein 0.0026 0.0057 0.0255
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0612 0.1044
Schistosoma mansoni ATPase 0.0117 0.0471 0.1182
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0026 0.0055 0.0914
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0176 0.0636
Brugia malayi calcium ATPase 0.004 0.0119 0.0538
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0152 0.063 0.0879
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0093 0.0359 0.0902
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0447
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.2462
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0019 0.0069
Onchocerca volvulus 0.0056 0.0191 0.1825
Loa Loa (eye worm) nuclear factor I 0.0015 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Giardia lamblia Hypothetical protein 0.0018 0.0019 0.0075
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0066 0.0238 0.0598
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0396 0.0993
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0055 0.0215
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0098 0.0981
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0665 0.1669
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.0191 0.303
Echinococcus granulosus death domain containing protein 0.0014 0.0001 0.0001
Echinococcus granulosus cation transporting atpase worm 0.0026 0.0055 0.0139
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0019 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0041
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0019 0.0304
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0143 0.0642
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.0552
Echinococcus granulosus copper transporting ATPase 1 0.0026 0.0055 0.0139
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0359 0.0613
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0076 0.1203
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0001 0.0002
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2206 1 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0019 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0332 0.4633
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.0091 0.1443
Trypanosoma brucei cation-transporting ATPase, putative 0.0026 0.0055 0.0771
Trypanosoma brucei glucosidase, putative 0.0035 0.0098 0.1366
Trichomonas vaginalis hypothetical protein 0.0034 0.0091 0.091
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0069 0.0253 0.1138
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0385 0.1694 0.2365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0118 0.1956
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0098 0.0981
Echinococcus granulosus lamin 0.0026 0.0057 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0019 0.0192
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0176 0.0636
Giardia lamblia hypothetical protein 0.0069 0.0253 0.0996
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0004 0.0009
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0069 0.0253 0.0634
Onchocerca volvulus 0.0019 0.0024 0.0233
Leishmania major DNA polymerase eta, putative 0.0171 0.0717 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.2462
Leishmania major hypothetical protein, conserved 0.0051 0.0169 0.2351
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0026 0.0055 0.0077
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Entamoeba histolytica cysteine proteinase 2 0.004 0.0118 0.1956
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Onchocerca volvulus 0.0056 0.0191 0.1825
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0019 0.0304
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0021 0.0054
Schistosoma mansoni netrin receptor unc5 0.0014 0.0001 0.0001
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0164 0.028
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0359 0.0613
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0076 0.0284 0.0713
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0101 0.0173
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0098 0.1366
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0218
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0053 0.021
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0019 0.0075
Toxoplasma gondii P-type ATPase PMA1 0.0053 0.0176 0.0635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0342 0.3428
Echinococcus multilocularis Chromobox protein 3 0.0034 0.0091 0.0228
Echinococcus multilocularis Chromo domain 0.0034 0.0091 0.0228
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0056 0.0192 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0019 0.0192
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0176 0.0795
Echinococcus granulosus Na:K ATPase alpha subunit 0.0066 0.0238 0.0598
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0041
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0019 0.0304
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0164 0.2289
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.0026 0.0428
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Loa Loa (eye worm) transcription factor SMAD2 0.0387 0.1702 0.6713
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0032
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0117 0.0471 0.748
Schistosoma mansoni hypothetical protein 0.0034 0.0091 0.0228
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0116 0.0468 0.1174
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.05 0.2219 0.5571
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0176 0.0301
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Giardia lamblia Encystation-specific protease 0.0018 0.0019 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi MAP kinase sur-1 0.005 0.0164 0.074
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0031 0.0436
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0137 0.0344
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0026 0.0055 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.0191 0.0752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0118 0.1183
Mycobacterium tuberculosis Probable reductase 0.0347 0.1518 0.2119
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Giardia lamblia DNA damage repair protein 0.0036 0.0101 0.0399
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0164 0.2289
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Echinococcus multilocularis neuropeptide receptor A26 0.046 0.2033 0.5103
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0169 0.2351
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0137 0.1914
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0069 0.0253 0.3524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0001 0.0005
Echinococcus granulosus cathepsin L 0.0018 0.0019 0.0048
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0012 0.0042
Giardia lamblia Myb 1-like protein 0.0061 0.0215 0.0849
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.002 0.0275
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0176 0.2462
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0069 0.0253 0.0634
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0308 0.0773
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0253 0.253
Schistosoma mansoni DNA helicase recq5 0.0019 0.0021 0.0054
Loa Loa (eye worm) hypothetical protein 0.0061 0.0215 0.0846
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Brugia malayi Peroxidasin 0.0026 0.0055 0.0246
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Leishmania major cathepsin L-like protease 0.0148 0.0612 0.8532
Brugia malayi cathepsin L-like precursor 0.0034 0.0092 0.0413
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0066 0.0238 0.0939
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.0094 0.0131
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0139
Echinococcus multilocularis cation transporting ATPase 13A1 0.0026 0.0055 0.0139
Loa Loa (eye worm) hypothetical protein 0.0122 0.0493 0.1944
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0385 0.1694 0.2365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0096
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0164 0.2289
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0012 0.0029
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0019 0.0048
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0057 0.0223
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.0117 0.1633
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0004 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0055 0.0914
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0019 0.0048
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0338 0.0849
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0012 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0055 0.0218
Echinococcus granulosus lamin dm0 0.0026 0.0057 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0108 0.108
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0019 0.0304
Onchocerca volvulus Huntingtin homolog 0.012 0.0484 0.4632
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0055 0.0522
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0634
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0055 0.0522
Trypanosoma cruzi cruzipain precursor, putative 0.0148 0.0612 0.1044
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0006
Echinococcus multilocularis copper transporting ATPase 1 0.0026 0.0055 0.0139
Loa Loa (eye worm) hypothetical protein 0.057 0.2535 1
Echinococcus multilocularis cpg binding protein 0.003 0.0072 0.0181
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0019 0.0075
Onchocerca volvulus 0.0026 0.0057 0.0544
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0069 0.0253 0.3524
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0073 0.0182
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0057 0.0142
Leishmania major cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.3524
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0098 0.0981
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Plasmodium falciparum DNA repair protein REV1, putative 0.0036 0.0101 0.1606
Schistosoma mansoni patched 1 0.0041 0.0125 0.0314
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0191 0.3158
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0191 0.0479
Leishmania major calcium motive p-type ATPase, putative 0.0066 0.0238 0.332
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0019 0.0304
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei chrX additional, unordered contigs 0.0036 0.0101 0.1411
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0091 0.091
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0118 0.0297
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0176 0.2803
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0091 0.1443
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0604 0.1517
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0125 0.1254
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0169 0.2677
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0019 0.0304
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus multilocularis cathepsin b 0.0018 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0004
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Echinococcus multilocularis cathepsin L 0.0018 0.0019 0.0048
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0057 0.0142
Plasmodium falciparum heterochromatin protein 1 0.0034 0.0091 0.1443
Loa Loa (eye worm) hypothetical protein 0.0069 0.0253 0.0996
Onchocerca volvulus 0.0122 0.0493 0.4715
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0143 0.1427
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0041 0.0147
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.0091 0.0228
Echinococcus multilocularis musashi 0.0026 0.0057 0.0143
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0176 0.0301
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0024 0.0388
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.0091 0.041
Loa Loa (eye worm) hypothetical protein 0.0311 0.1355 0.5344
Echinococcus granulosus cathepsin L 0.004 0.0118 0.0297
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0137 0.0618
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0113 0.0508
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Loa Loa (eye worm) cathepsin B 0.0018 0.0019 0.0075
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0443
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.0191 0.0479
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0074 0.0275 0.1238
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.1504
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0012 0.0042
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0137 0.2271
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0183 0.046
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.3524
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0622 0.2773 0.2773
Trypanosoma brucei trypanothione reductase 0.0152 0.063 0.8782
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0098 0.0441
Trypanosoma brucei DNA polymerase IV, putative 0.0136 0.0557 0.7769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni peroxidasin 0.0026 0.0055 0.0137
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0612 0.1044
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0101 0.1411
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Entamoeba histolytica hypothetical protein 0.0034 0.0091 0.1504
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0104 0.1045
Brugia malayi MH2 domain containing protein 0.0026 0.0057 0.0255
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0665 0.2622
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0026 0.0055 0.0553
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0176 0.0176
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0098 0.0386
Leishmania major cathepsin L-like protease 0.0148 0.0612 0.8532
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0001 0.0003
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0176 0.2458
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Schistosoma mansoni loxhd1 0.0019 0.0024 0.0061
Loa Loa (eye worm) hypothetical protein 0.0122 0.0493 0.1946
Brugia malayi glutathione reductase 0.0152 0.063 0.2837
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0026 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Schistosoma mansoni hypothetical protein 0.0282 0.1225 0.3075
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0245 0.0967
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0266 0.0667
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0021 0.0054
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0238 0.0406
Brugia malayi chromobox protein homolog 3 0.0089 0.0342 0.1542
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.3524
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0137 0.0541
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0012 0.002
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0026 0.0055 0.0249
Brugia malayi MH1 domain containing protein 0.0026 0.0057 0.0255
Echinococcus multilocularis neuropeptide s receptor 0.046 0.2033 0.5103
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0101 0.0396 0.0993
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0069 0.0253 0.4012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0055 0.0553
Brugia malayi CHD4 protein 0.0036 0.0098 0.0443
Echinococcus multilocularis smad 0.0026 0.0057 0.0142
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0242 0.2421
Leishmania major cysteine peptidase A (CPA) 0.0056 0.0191 0.2661
Echinococcus multilocularis lamin 0.0026 0.0057 0.0143
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0019 0.0086
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0098 0.0387
Trypanosoma cruzi P-type H+-ATPase, putative 0.0036 0.0101 0.0172
Schistosoma mansoni hypothetical protein 0.0051 0.0168 0.0421
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.0117 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0116 0.0468 0.1174
Onchocerca volvulus 0.0064 0.0227 0.2173
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0091 0.0328
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0093 0.0359 0.5012
Echinococcus multilocularis cathepsin L 0.004 0.0118 0.0297
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0067 0.0668
Plasmodium falciparum glutathione reductase 0.0152 0.063 1
Entamoeba histolytica hypothetical protein 0.0034 0.0091 0.1504
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0057 0.0142
Mycobacterium ulcerans hypothetical protein 0.0036 0.0101 0.0101
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Toxoplasma gondii cathepsin CPC1 0.0018 0.0019 0.0069
Trichomonas vaginalis pc-MYB2, putative 0.0061 0.0214 0.2143
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0026 0.0055 0.0055
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0026 0.0055 0.0199
Schistosoma mansoni cpg binding protein 0.003 0.0072 0.0181
Brugia malayi hypothetical protein 0.0122 0.0493 0.2223
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.057 0.2535 0.6366
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0192
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0101 0.1411
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0118 0.0297
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0019 0.0304
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0376 0.0945
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.5947
Plasmodium falciparum copper-transporting ATPase 0.0026 0.0055 0.0878
Brugia malayi Smad1 0.0026 0.0057 0.0255
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0565 0.142
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0093 0.0359 0.1417
Onchocerca volvulus 0.0243 0.1045 1
Trichomonas vaginalis chromobox protein, putative 0.015 0.0621 0.6216
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0036 0.0101 0.0398
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0622 0.2773 1
Leishmania major cathepsin L-like protease 0.0148 0.0612 0.8532
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0001 0.0004
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0073 0.0182
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0137 0.1374
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0137 0.2271
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0066 0.0238 0.0598
Echinococcus granulosus neuropeptide receptor A26 0.046 0.2033 0.5103
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0176 0.2462
Onchocerca volvulus Peroxidase homolog 0.0026 0.0055 0.0522
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0182
Echinococcus granulosus tar DNA binding protein 0.0068 0.0245 0.0615
Loa Loa (eye worm) hypothetical protein 0.0069 0.0253 0.0996
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0113 0.0508
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.057 0.2535 1
Echinococcus granulosus chromobox protein 2 0.0034 0.0091 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0084 0.0379
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0098 0.0353
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Plasmodium falciparum calcium-transporting ATPase 0.0101 0.0396 0.6284
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0137 0.0344
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.0621 0.2448
Brugia malayi hypothetical protein 0.0146 0.0604 0.2723
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.3022 0.7588
Loa Loa (eye worm) E1-E2 ATPase 0.0053 0.0176 0.0695
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.0191 0.303
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0176 0.2458
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0403 0.1591
Echinococcus granulosus chromobox protein 1 0.015 0.0621 0.1558
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0308 0.1388
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0771
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0057 0.0142
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0665 0.2996
Plasmodium vivax P-type ATPase4, putative 0.0117 0.0471 0.748
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0036 0.0101 0.0172
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Entamoeba histolytica hypothetical protein 0.0023 0.0041 0.0675
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0041 0.0648
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0055 0.0139
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0634
Trypanosoma cruzi cysteine protease, putative 0.004 0.0118 0.0202
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0242 0.0607
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0447
Brugia malayi TAR-binding protein 0.0068 0.0245 0.1104
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0347 0.1518 0.2119
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Brugia malayi hypothetical protein 0.0232 0.0994 0.4478
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Schistosoma mansoni Smad4 0.0026 0.0057 0.0142
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Schistosoma mansoni alpha-glucosidase 0.0137 0.0563 0.1414
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0564
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0019 0.0086
Loa Loa (eye worm) hypothetical protein 0.003 0.0073 0.0286
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0001 0.0003
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0338 0.0849
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1584 0.7163 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0117 0.0471 0.1182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0137 0.1374
Loa Loa (eye worm) hypothetical protein 0.0082 0.0308 0.1215
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0117 0.0471 0.1182
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni alpha glucosidase 0.0035 0.0098 0.0246
Echinococcus granulosus dna polymerase eta 0.0171 0.0717 0.18
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0019 0.0304
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0245 0.0967
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0019 0.0033
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0069 0.0253 0.1138
Schistosoma mansoni rab6-interacting 0.0019 0.0024 0.0061
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0117 0.1866
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0497 0.6933
Loa Loa (eye worm) calcium ATPase 0.0057 0.0195 0.0768
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0019 0.0048
Brugia malayi ImpB/MucB/SamB family protein 0.0171 0.0717 0.3231
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0069 0.0253 0.0431
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0443
Schistosoma mansoni hypothetical protein 0.0023 0.004 0.0102
Echinococcus multilocularis cysteine protease 0.0056 0.0191 0.0479
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0117 0.0471 0.0471
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0183 0.046
Schistosoma mansoni hypothetical protein 0.0887 0.3983 1
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0118 0.0202
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Brugia malayi Heterochromatin protein 1 0.015 0.0621 0.2796
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0191 0.3158
Plasmodium vivax unspecified product 0.0018 0.0019 0.0304
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0019 0.0086
Loa Loa (eye worm) hypothetical protein 0.0051 0.0168 0.0661
Plasmodium falciparum phosphodiesterase gamma, putative 0.0069 0.0253 0.4012
Trypanosoma cruzi DNA polymerase eta, putative 0.0171 0.0717 0.1224
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0083 0.0313 0.0313
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0036 0.0101 0.0364
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0069 0.0253 0.4012
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.0191 0.303
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Loa Loa (eye worm) hypothetical protein 0.012 0.0484 0.1909
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0359 0.5012
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0019 0.0267
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0083 0.0313 0.5186
Trichomonas vaginalis MYB3r3, putative 0.0061 0.0214 0.2143
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0137 0.1914
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0101 0.0173
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0091 0.1443
Echinococcus granulosus cathepsin l1 0.0034 0.0092 0.023
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0101 0.1411
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0065 0.0231 0.0394
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0164 0.0412
Leishmania major copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0771
Plasmodium vivax unspecified product 0.0022 0.0035 0.056
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Leishmania major P-type ATPase, putative 0.0076 0.0284 0.3961
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0098 0.0167
Echinococcus granulosus Smad4 0.0026 0.0057 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0342 0.3274
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0084 0.0331
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0083 0.0313 0.1236
Plasmodium falciparum thioredoxin reductase 0.0152 0.063 1
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0041 0.0569
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0004 0.0009
Trypanosoma brucei calcium-translocating P-type ATPase 0.0101 0.0396 0.5519
Loa Loa (eye worm) cysteine protease 0.0056 0.0191 0.0752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0118 0.1183
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0066 0.0238 0.0939
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0164 0.0412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Echinococcus multilocularis cation transporting atpase worm 0.0026 0.0055 0.0139
Leishmania major DNA polymerase kappa, putative 0.0123 0.0497 0.6933
Mycobacterium ulcerans DNA polymerase IV 0.0143 0.0586 0.0586
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus multilocularis GPCR, family 2 0.0032 0.0084 0.0211
Loa Loa (eye worm) hypothetical protein 0.003 0.0073 0.0289
Onchocerca volvulus 0.0026 0.0055 0.0522
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0019 0.0304
Schistosoma mansoni smad1 5 8 and 0.0026 0.0057 0.0142
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0095 0.0369 0.3532
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0362
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0396 0.0993
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Onchocerca volvulus 0.0047 0.0152 0.1453
Onchocerca volvulus 0.0122 0.0493 0.4715
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0041 0.0041
Echinococcus granulosus geminin 0.0887 0.3983 1
Loa Loa (eye worm) Smad1 0.0026 0.0057 0.0223
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0191 0.1825
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Schistosoma mansoni cpg binding protein 0.003 0.0072 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Toxoplasma gondii cathepsin B 0.0018 0.0019 0.0069
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0057 0.0256
Treponema pallidum cation-transporting ATPase, P-type 0.0026 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.007 0.0256 0.0642
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0164 0.0412
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0026 0.0055 0.0139
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Echinococcus granulosus RUN 0.0019 0.0024 0.0061
Brugia malayi Cytochrome P450 family protein 0.0026 0.0053 0.024
Echinococcus granulosus cathepsin b 0.0018 0.0019 0.0048
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0994 0.2495
Schistosoma mansoni copper ABC transporter ATPase 0.0026 0.0055 0.0139
Schistosoma mansoni rab6-interacting 0.0019 0.0024 0.0061
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0176 0.0176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0176
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0586 0.8181
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0004 0.0051
Plasmodium vivax copper-transporting ATPase, putative 0.0026 0.0055 0.0878
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0001 0.0002
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0284 0.0713
Brugia malayi Membrane calcium atpase protein 3 0.0076 0.0284 0.128
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0073 0.0262
Mycobacterium tuberculosis Probable oxidoreductase 0.0385 0.1694 0.2365
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0001 0.0001
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis cation transporting ATPase 13A3 0.0026 0.0055 0.0139
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0256 0.1152
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Brugia malayi Pre-SET motif family protein 0.0205 0.087 0.392
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0176 0.0301
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0084 0.0211
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0007 0.0098
Echinococcus multilocularis thioredoxin glutathione reductase 0.0152 0.063 0.1581
Trichomonas vaginalis MYB, putative 0.0061 0.0215 0.2156
Onchocerca volvulus 0.0083 0.0313 0.2998
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0191 0.0479
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0098 0.1621
Treponema pallidum NADH oxidase 0.0053 0.0176 0.0176
Plasmodium vivax SET domain protein, putative 0.003 0.0073 0.1152
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0176 0.0176
Schistosoma mansoni lamin 0.0026 0.0057 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0245 0.1104
Loa Loa (eye worm) hypothetical protein 0.0046 0.0147 0.0579
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0101 0.0396 0.1783
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0019 0.0086
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0024 0.0388
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0253 0.253
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1584 0.7163 1
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0055 0.0522
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0019 0.0304
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0046 0.0769
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0332 0.4633
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0096
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0634
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0098 0.0246
Brugia malayi hypothetical protein 0.0051 0.0169 0.076
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0118 0.0297
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0152 0.0685
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0143 0.0586 0.5874
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0096 0.1343
Echinococcus granulosus cysteine protease 0.004 0.0118 0.0297
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.0191 0.0752
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0362
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0065 0.0255
Brugia malayi CXXC zinc finger family protein 0.0028 0.0065 0.0291
Schistosoma mansoni chromobox protein 0.015 0.0621 0.1558
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0092 0.0919
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0069 0.0253 0.0634
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0092 0.1519
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0012
Schistosoma mansoni survival motor neuron protein 0.0047 0.0152 0.0381
Entamoeba histolytica hypothetical protein 0.0034 0.0091 0.1504
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0041 0.0057
Plasmodium vivax unspecified product 0.004 0.0118 0.1877
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Leishmania major hypothetical protein, conserved 0.0069 0.0253 0.3524
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0092 0.0413
Brugia malayi E1-E2 ATPase family protein 0.0053 0.0176 0.0794
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Brugia malayi Doublecortin family protein 0.0019 0.0024 0.011
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0019 0.0304
Schistosoma mansoni hypothetical protein 0.0019 0.0024 0.0061
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0077
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0149 0.067
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0176 0.1768
Schistosoma mansoni DNA polymerase IV / kappa 0.0036 0.0101 0.0254
Loa Loa (eye worm) PDE1B protein 0.0069 0.0253 0.0996
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0665 0.1669
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0238 0.0406
Toxoplasma gondii cathepsin CPL 0.0056 0.0191 0.0688
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0176 0.2462
Plasmodium vivax vivapain-3 0.004 0.0118 0.1877
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0026 0.0055 0.0077
Schistosoma mansoni DNA polymerase eta 0.0171 0.0717 0.18
Giardia lamblia Cathepsin L-like protease 0.0018 0.0019 0.0075
Echinococcus multilocularis chromobox protein 2 0.0034 0.0091 0.0228
Loa Loa (eye worm) calcium ATPase 0.002 0.0026 0.0102
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0019 0.0048
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Plasmodium vivax vivapain-2 0.0056 0.0191 0.303
Echinococcus granulosus bloom syndrome protein 0.0045 0.0143 0.0358
Onchocerca volvulus 0.0028 0.0065 0.0619
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0041 0.0569
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0118 0.0297
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0253 0.253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.0552
Leishmania major calcium-translocating P-type ATPase 0.0117 0.0471 0.657
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0227 0.057
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0057 0.0142
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0093 0.0359 0.5012
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0036 0.0101 0.0455
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Onchocerca volvulus Cathepsin F homolog 0.0056 0.0191 0.1825
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trichomonas vaginalis cation-transporting ATPase, putative 0.0093 0.0359 0.3599
Echinococcus granulosus smad 0.0026 0.0057 0.0142
Trichomonas vaginalis C-MYB, putative 0.0061 0.0214 0.2143
Trypanosoma brucei protein kinase, putative 0.005 0.0164 0.2289
Brugia malayi cathepsin L precursor 0.0018 0.0019 0.0086
Entamoeba histolytica deoxycytidyl transferase, putative 0.0116 0.0468 0.7739
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Giardia lamblia Copper-transporting P-type ATPase 0.0026 0.0055 0.0218
Echinococcus granulosus GPCR family 2 0.0032 0.0084 0.0211
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.012 0.1202
Schistosoma mansoni alpha-glucosidase 0.0137 0.0563 0.1414
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0091 0.091
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0176 0.2462
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0376 0.1697
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0116 0.0468 0.1174
Echinococcus granulosus peroxidasin 0.0026 0.0055 0.0137
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0359 0.5012
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0026 0.0055 0.0139
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0099 0.0249
Schistosoma mansoni DNA helicase recq1 0.0019 0.0021 0.0054
Plasmodium falciparum phosphodiesterase delta, putative 0.0069 0.0253 0.4012
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Onchocerca volvulus 0.0034 0.0092 0.0878
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi hypothetical protein 0.0019 0.0024 0.011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0385 0.1694 0.2365
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0094
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0019 0.0267
Schistosoma mansoni polycystin 1-related 0.0019 0.0024 0.0061
Echinococcus granulosus Chromo domain 0.0034 0.0091 0.0228
Onchocerca volvulus 0.0019 0.0024 0.0233
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0102 0.0403 0.1591
Brugia malayi calcium ATPase 0.0036 0.0101 0.0455
Loa Loa (eye worm) hypothetical protein 0.0171 0.0717 0.2827
Plasmodium vivax DNA repair protein REV1, putative 0.0036 0.0101 0.1606
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0176 0.2462
Echinococcus multilocularis Smad4 0.0026 0.0057 0.0142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.0091 0.041
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0117 0.0471 0.0804
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0218
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0019 0.0075
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0604 0.1517
Schistosoma mansoni smad1 5 8 and 0.0026 0.0057 0.0142
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0069 0.0253 0.0634
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0118 0.0202
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) helicase 0.0034 0.0091 0.0358
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0125 0.0314
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0051
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0091 0.1443
Schistosoma mansoni ATPase 0.0117 0.0471 0.1182
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0021 0.0054
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.012 0.1202
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.1504
Schistosoma mansoni chromobox protein 0.0034 0.0091 0.0228
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0007 0.0028
Trichomonas vaginalis cation-transporting ATPase, putative 0.0117 0.0471 0.4717
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0084 0.0211
Echinococcus multilocularis RUN 0.0019 0.0024 0.0061
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.05 0.2219 0.8752
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0004 0.0014
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis X box binding protein 1 0.0282 0.1225 0.3075
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0376 0.6232
Loa Loa (eye worm) hypothetical protein 0.0056 0.0191 0.0752
Echinococcus granulosus neuropeptide s receptor 0.046 0.2033 0.5103
Echinococcus multilocularis cathepsin b 0.0018 0.0019 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0057 0.0224
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Schistosoma mansoni smad1 5 8 and 0.0026 0.0057 0.0142
Loa Loa (eye worm) glutathione reductase 0.0152 0.063 0.2483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0369 0.3698
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0157 0.0395
Plasmodium vivax thioredoxin reductase, putative 0.0152 0.063 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0362
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0176 0.2462
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.044 0.0751
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) hypothetical protein 0.0062 0.022 0.0868
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0215 0.2156
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0184 0.0665
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Loa Loa (eye worm) thioredoxin reductase 0.0152 0.063 0.2483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0564
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0266 0.0667
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.0091 0.0228
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0083 0.0313 0.0787
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0176 0.0246
Schistosoma mansoni hypothetical protein 0.0887 0.3983 1
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0019 0.0304
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Loa Loa (eye worm) hypothetical protein 0.0069 0.0253 0.0996
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0586 0.8181
Loa Loa (eye worm) ctsf protein 0.0056 0.0191 0.0752
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0176 0.0176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0091 0.091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0004 0.0016
Echinococcus multilocularis peroxidasin 0.0026 0.0055 0.0137
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Onchocerca volvulus Peroxidase homolog 0.0026 0.0055 0.0522
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0091 0.035 0.1264
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0001 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Trichomonas vaginalis pc-MYB2, putative 0.0061 0.0214 0.2143
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0012 0.0042
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0069 0.0253 0.0634
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0069 0.0253 0.0634
Echinococcus multilocularis geminin 0.0887 0.3983 1
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0101 0.1411
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0046 0.0648
Trichomonas vaginalis chromobox protein, putative 0.015 0.0621 0.6216
Echinococcus granulosus intermediate filament protein 0.0026 0.0057 0.0143
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Echinococcus multilocularis protein dispatched 1 0.0047 0.0152 0.0381
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0493 0.2221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0164 0.0647
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0012 0.0029
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0164 0.028
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0051
Brugia malayi Cathepsin L-like precursor 0.0034 0.0092 0.0413
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Plasmodium vivax vivapain-1 0.004 0.0118 0.1877
Leishmania major P-type H -ATPase, putative 0.0053 0.0176 0.2458
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0164 0.028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0071 0.0712
Toxoplasma gondii melibiase subfamily protein 0.01 0.0394 0.1422
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0342 0.3428
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0019 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0106 0.1067
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0026 0.0055 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0118 0.0202
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0026 0.0055 0.0077
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0093 0.0359 0.5012
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0096 0.0164
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0137 0.1374
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0215 0.2156
Brugia malayi Valyl-tRNA synthetase 0.0034 0.0091 0.041
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0035 0.0139
Schistosoma mansoni hypothetical protein 0.0047 0.0152 0.0381
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi hypothetical protein 0.0017 0.0012 0.0052
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0019 0.0183
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0069 0.0253 0.1138
Loa Loa (eye worm) hypothetical protein 0.007 0.0256 0.1008
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0056 0.0192 0.0867
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0403 0.1818
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0176 0.1765
Schistosoma mansoni type V p-type atpase isoform 0.0026 0.0055 0.0139
Loa Loa (eye worm) hypothetical protein 0.0041 0.0125 0.0494
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0137 0.0234
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0443
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0245 0.0615
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0069 0.0253 0.0634
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0125 0.0494
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi hypothetical protein 0.012 0.0484 0.2182
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0024 0.0061
Onchocerca volvulus 0.0056 0.0191 0.1825
Brugia malayi CHE-14 protein 0.0041 0.0125 0.0564
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.253
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0041 0.0648
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0118 0.1648
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0019 0.0304
Echinococcus granulosus cation transporting ATPase 13A1 0.0026 0.0055 0.0139
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0091 0.0328
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0019 0.0086
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0093 0.0359 0.0902
Schistosoma mansoni peroxidasin 0.0026 0.0055 0.0137
Trypanosoma cruzi trypanothione reductase, putative 0.0152 0.063 0.1075
Leishmania major cytochrome p450-like protein 0.0016 0.0007 0.0098
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0012 0.0029
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0076 0.0284 0.0713
Brugia malayi Melibiase family protein 0.0067 0.0242 0.1089
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0019 0.0033
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0118 0.0532
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Onchocerca volvulus 0.0082 0.0308 0.2947
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.05 0.2219 1
Treponema pallidum hypothetical protein 0.0017 0.0012 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0347 0.1518 0.2119
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0403 0.1818
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0191 0.0326
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.0224
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.5947
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0098 0.0247
Onchocerca volvulus 0.0026 0.0057 0.0544
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0176 0.1768
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0182
Loa Loa (eye worm) hypothetical protein 0.0232 0.0994 0.3919
Brugia malayi hypothetical protein 0.0033 0.0086 0.0389
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0066 0.0238 0.332
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0019 0.0304
Brugia malayi MH2 domain containing protein 0.0026 0.0057 0.0255
Onchocerca volvulus Huntingtin homolog 0.012 0.0484 0.4632
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0019 0.0304
Plasmodium vivax phosphodiesterase gamma, putative 0.0069 0.0253 0.4012
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0242 0.0607
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Loa Loa (eye worm) hypothetical protein 0.0067 0.0242 0.0953
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0308 0.0773
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0338 0.0849
Onchocerca volvulus 0.0048 0.0157 0.1506
Echinococcus multilocularis expressed conserved protein 0.0091 0.035 0.0878
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0012 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0057 0.0195 0.3221
Mycobacterium ulcerans DNA polymerase IV 0.0143 0.0586 0.0586
Leishmania major calcium-transporting ATPase, putative 0.0066 0.0238 0.332
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0118 0.0532
Leishmania major DNA damage repair protein, putative 0.0036 0.0101 0.1411
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0098 0.0167
Schistosoma mansoni intermediate filament proteins 0.0026 0.0057 0.0143
Brugia malayi Protein cec-1. 0.0034 0.0091 0.041
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0019 0.0304
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0564
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0012 0.0029
Brugia malayi Death domain containing protein 0.0014 0.0001 0.0002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0347 0.1518 0.2119
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0125 0.0314
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0093 0.0359 0.3599
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0188 0.1879
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.0513 0.0875
Brugia malayi polk-prov protein 0.0062 0.022 0.0992
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0046 0.0079
Leishmania major P-type H -ATPase, putative 0.0053 0.0176 0.2458
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0998 1
Onchocerca volvulus 0.0056 0.0191 0.1825
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0019 0.0048
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0019 0.0048
Plasmodium falciparum glutathione reductase 0.0053 0.0176 0.2803
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0026 0.0055 0.0077
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0061 0.0215 0.0776
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0056 0.0192 0.0759
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0497 0.0694
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0139
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0383 0.0962
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0143 0.0358
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Trypanosoma cruzi cysteine peptidase, putative 0.1298 0.5856 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0164 0.0592
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0347 0.1518 0.2119
Trichomonas vaginalis MYB72, putative 0.0061 0.0214 0.2143
Toxoplasma gondii cathepsin CPC2 0.0018 0.0019 0.0069
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0094
Onchocerca volvulus 0.0056 0.0191 0.1825
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0019 0.0192
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi SET domain containing protein 0.0036 0.0099 0.0444
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0076 0.0284 0.0713
Schistosoma mansoni cathepsin C 0.0018 0.0019 0.0048
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0019 0.0304
Echinococcus multilocularis chromobox protein 1 0.015 0.0621 0.1558
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0143 0.1427
Trypanosoma cruzi cation-transporting ATPase, putative 0.0026 0.0055 0.0094
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0137 0.1914
Schistosoma mansoni lamin 0.0026 0.0057 0.0143
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0019 0.0075
Brugia malayi Thioredoxin reductase 0.0152 0.063 0.2837
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0191 0.0479
Loa Loa (eye worm) hypothetical protein 0.0061 0.0215 0.0847
Schistosoma mansoni chromobox protein 0.015 0.0621 0.1558
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.1765 0.4433
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0041 0.0057
Loa Loa (eye worm) hypothetical protein 0.0083 0.0313 0.1236
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0164 0.0412
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2206 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0182
Brugia malayi Blistered cuticle protein 3 0.0026 0.0055 0.0246
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0069 0.0253 0.0634
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.0131 0.0471
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0169 0.2677
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0026 0.0055 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Brugia malayi E1-E2 ATPase family protein 0.0026 0.0055 0.0249
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0137 0.1914
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0125 0.0314
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0019 0.0304
Brugia malayi hypothetical protein 0.0119 0.0481 0.2166
Echinococcus granulosus expressed conserved protein 0.0091 0.035 0.0878
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Loa Loa (eye worm) RNA binding protein 0.0068 0.0245 0.0967
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0139
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0019 0.0304
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0026 0.0055 0.0199
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0176 0.2803
Plasmodium vivax vivapain-2 0.0056 0.0191 0.303
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0041 0.0147
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.0191 0.086
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0098 0.0246
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Loa Loa (eye worm) hypothetical protein 0.0097 0.0376 0.1485
Schistosoma mansoni lipoxygenase 0.0054 0.0183 0.046
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0056 0.0192 0.0269
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0191 0.0479
Schistosoma mansoni lipoxygenase 0.0019 0.0024 0.0061
Onchocerca volvulus 0.0233 0.0999 0.9557
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Giardia lamblia DINP protein human, muc B family 0.0123 0.0497 0.196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.057 0.2535 0.9142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0092 0.0919
Plasmodium falciparum thioredoxin reductase 0.0053 0.0176 0.2803
Echinococcus multilocularis cysteine protease 0.0056 0.0191 0.0479
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0191 0.0479
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.0091 0.091
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.022 0.3069
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.3022 0.7588
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0026 0.0055 0.0553
Chlamydia trachomatis metal transport ATPase 0.0026 0.0055 0.0055
Brugia malayi fibroinase precursor 0.0018 0.0019 0.0086
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0074 0.0275 0.1083
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0021 0.0084
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Schistosoma mansoni cathepsin s 0.0022 0.0035 0.0088
Brugia malayi Protein kinase domain containing protein 0.0015 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0218
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0117 0.0471 0.1182
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0098 0.0247
Echinococcus granulosus tumor protein p63 0.0331 0.1447 0.3634
Brugia malayi MH2 domain containing protein 0.0387 0.1702 0.767
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Echinococcus multilocularis dna polymerase eta 0.0171 0.0717 0.18
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Giardia lamblia Hypothetical protein 0.0069 0.0253 0.0996
Toxoplasma gondii P-type ATPase4, putative 0.0083 0.0313 0.113
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0055 0.0553
Schistosoma mansoni terminal deoxycytidyl transferase 0.0116 0.0468 0.1174
Trypanosoma brucei unspecified product 0.008 0.0303 0.4222
Schistosoma mansoni hypothetical protein 0.0146 0.0604 0.1517
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0118 0.1877
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.0091 0.1443
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0069 0.0253 0.0634
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0176 0.0301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0347 0.1518 0.2119
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0284 0.0713
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.0028
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0003
Onchocerca volvulus 0.0018 0.0019 0.0183
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0076 0.0284 0.1024
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Onchocerca volvulus 0.0061 0.0215 0.2053
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0084 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0019 0.0192
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.5947
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0019 0.0304
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0369 0.3698
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0019 0.0304
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0041 0.0041
Plasmodium vivax cation transporting ATPase, putative 0.0026 0.0055 0.0878
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0101 0.0173
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0055 0.0139
Echinococcus multilocularis calcium transporting atpase 0.0101 0.0396 0.0993
Entamoeba histolytica hypothetical protein 0.0018 0.0019 0.0317
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0056 0.0192 0.0192
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Echinococcus granulosus Chromobox protein 3 0.0034 0.0091 0.0228
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0106 0.1067
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.0191 0.0479
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0565 0.142
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Echinococcus multilocularis dna polymerase kappa 0.0143 0.0586 0.1472
Echinococcus granulosus microtubule associated protein 2 0.0677 0.3022 0.7588
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0003
Trichomonas vaginalis DNA polymerase eta, putative 0.0143 0.0586 0.5874
Echinococcus granulosus cathepsin l1 0.0056 0.0191 0.0479
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0086 0.0309
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.0091 0.0228
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.05 0.2219 0.5571
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0069 0.0253 0.0634
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0032
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0024 0.0061
Brugia malayi follicle stimulating hormone receptor 0.0234 0.1004 0.4524
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0994 0.2495
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0069 0.0253 0.1138
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0084 0.0211
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0116 0.0468 0.1844
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0001 0.0001
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Brugia malayi hypothetical protein 0.0026 0.0055 0.0246
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0069 0.0253 0.0634
Loa Loa (eye worm) hypothetical protein 0.0051 0.0169 0.0665
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0057 0.0195 0.3221
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0338 0.0849
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus granulosus thioredoxin glutathione reductase 0.0152 0.063 0.1581
Trypanosoma brucei unspecified product 0.008 0.0303 0.4222
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0604 0.1517
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0055 0.0914
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0191 0.0479
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0026 0.0055 0.0055
Echinococcus granulosus chromobox protein 1 0.015 0.0621 0.1558
Onchocerca volvulus 0.0026 0.0055 0.0522
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0284 0.2844
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Leishmania major DNA polymerase kappa, putative 0.0036 0.0101 0.1411
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0019 0.0086
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0376 0.0945
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0137 0.0234
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0468 0.2107
Schistosoma mansoni hypothetical protein 0.0401 0.1765 0.4433
Schistosoma mansoni chromobox protein 0.0034 0.0091 0.0228
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.004 0.0102
Echinococcus multilocularis chromobox protein 1 0.015 0.0621 0.1558
Echinococcus granulosus dna polymerase kappa 0.0143 0.0586 0.1472
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0091 0.091
Onchocerca volvulus 0.0026 0.0055 0.0522

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 100 uM Cytotoxicity of the compound was evaluated against uninfected MT-4 cells ChEMBL. 9873448
CC50 (functional) > 100 uM Cytotoxicity of the compound was evaluated against uninfected MT-4 cells ChEMBL. 9873448
IC50 (functional) = 1 uM Inhibitory activity against syncytia formation in HIV-infected MT-4 cells was evaluated ChEMBL. 9873448
IC50 (functional) = 1 uM Inhibitory activity against syncytia formation in HIV-infected MT-4 cells was evaluated ChEMBL. 9873448
Inhibition (binding) = 50 % In vitro inhibitory activity of the compound against HIV-1 protease at a concentration of 10 microM ChEMBL. No reference
Inhibition (binding) = 50 % In vitro inhibitory activity of the compound against HIV-1 protease at a concentration of 10 microM ChEMBL. No reference
logP (ADMET) = 4.12 Partition coefficient (logP) ChEMBL. 9873448

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9873448

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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