Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | neuroligin | 0.0152 | 0.1252 | 0.1252 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0095 | 0.0587 | 0.0587 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0152 | 0.1252 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | carboxylesterase | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | microtubule associated protein 2 | 0.069 | 0.7567 | 0.7567 |
Schistosoma mansoni | kinase | 0.0048 | 0.0042 | 0.0042 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.0075 | 0.0075 |
Onchocerca volvulus | 0.0152 | 0.1252 | 1 | |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.0075 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0152 | 0.1252 | 0.1252 |
Brugia malayi | Carboxylesterase family protein | 0.0152 | 0.1252 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0898 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.069 | 0.7567 | 0.7567 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0095 | 0.0587 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0075 | 0.0387 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0152 | 0.1252 | 0.1252 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0152 | 0.1252 | 0.1252 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Loa Loa (eye worm) | carboxylesterase | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.0075 | 0.0075 |
Onchocerca volvulus | 0.0152 | 0.1252 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0075 | 0.0387 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0095 | 0.0587 | 0.0587 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0898 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0898 | 1 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.0075 | 0.0075 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0095 | 0.0587 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.0075 | 0.0075 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0075 | 0.0387 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Giardia lamblia | Kinase, PLK | 0.0095 | 0.0587 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0152 | 0.1252 | 0.1252 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | carboxylesterase 5A | 0.0898 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Schistosoma mansoni | acetylcholinesterase | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0095 | 0.0587 | 0.0587 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0095 | 0.0587 | 0.0587 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0152 | 0.1252 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0898 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Onchocerca volvulus | 0.0152 | 0.1252 | 1 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0152 | 0.1252 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | acetylcholinesterase | 0.0898 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.0075 | 0.0075 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0075 | 0.0387 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0152 | 0.1252 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.0587 | 0.4568 |
Onchocerca volvulus | 0.0152 | 0.1252 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Echinococcus multilocularis | acetylcholinesterase | 0.0898 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0058 | 0.0058 |
Brugia malayi | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0152 | 0.1252 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0152 | 0.1252 | 0.1252 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.0075 | 0.0075 |
Echinococcus multilocularis | neuroligin | 0.0152 | 0.1252 | 0.1252 |
Onchocerca volvulus | 0.0152 | 0.1252 | 1 | |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0095 | 0.0587 | 0.5 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0095 | 0.0587 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0898 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0152 | 0.1252 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0898 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0898 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0898 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1252 | 0.1252 |
Trypanosoma brucei | polo-like protein kinase | 0.0095 | 0.0587 | 1 |
Schistosoma mansoni | gliotactin | 0.0152 | 0.1252 | 0.1252 |
Brugia malayi | Carboxylesterase family protein | 0.0152 | 0.1252 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0058 | 0.0058 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0095 | 0.0587 | 0.0587 |
Schistosoma mansoni | microtubule-associated protein tau | 0.069 | 0.7567 | 0.7567 |
Echinococcus multilocularis | acetylcholinesterase | 0.0898 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0152 | 0.1252 | 0.1252 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0152 | 0.1252 | 0.1252 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0058 | 0.0058 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.