Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0384 | 1 | 1 |
Onchocerca volvulus | 0.0384 | 1 | 1 | |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0261 | 0.2725 | 0.2725 |
Loa Loa (eye worm) | SRC-1 | 0.0384 | 1 | 1 |
Brugia malayi | SRC-1 | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK protein kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0384 | 1 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0261 | 0.2725 | 0.2725 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0384 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0384 | 1 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0384 | 1 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0297 | 0.4866 | 0.4866 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0297 | 0.4866 | 0.4866 |
Brugia malayi | Protein kinase domain containing protein | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine kinase | 0.0384 | 1 | 1 |
Onchocerca volvulus | 0.0384 | 1 | 1 | |
Onchocerca volvulus | 0.0384 | 1 | 1 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Onchocerca volvulus | 0.0384 | 1 | 1 | |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0384 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0261 | 0.2725 | 0.2725 |
Schistosoma mansoni | tyrosine kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0384 | 1 | 1 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0384 | 1 | 1 |
Onchocerca volvulus | 0.0384 | 1 | 1 | |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0384 | 1 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.0384 | 1 | 1 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0297 | 0.4866 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0384 | 1 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0297 | 0.4866 | 0.4866 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0297 | 0.4866 | 0.4866 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0384 | 1 | 1 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Echinococcus granulosus | c src tyrosine kinase | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0384 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0384 | 1 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0384 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0384 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0297 | 0.4866 | 0.4866 |
Onchocerca volvulus | 0.0384 | 1 | 1 | |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0297 | 0.4866 | 0.5 |
Echinococcus granulosus | tyrosine kinase | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0384 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0261 | 0.2725 | 0.2725 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0384 | 1 | 1 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0384 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0384 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0297 | 0.4866 | 0.4866 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0384 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0384 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0384 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0384 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.