Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.1105 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0165 | 0.2849 | 0.4031 |
Brugia malayi | glutaminase DH11.1 | 0.0264 | 0.5204 | 0.4608 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0222 | 0.4208 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.1105 | 0.5 |
Loa Loa (eye worm) | glutaminase 2 | 0.0264 | 0.5204 | 0.5166 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.1105 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.7025 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0264 | 0.5204 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Echinococcus granulosus | geminin | 0.0341 | 0.7025 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0127 | 0.1951 | 0.1428 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.008 | 0.0073 |
Mycobacterium ulcerans | glutaminase | 0.0264 | 0.5204 | 0.5 |
Echinococcus granulosus | tumor protein p63 | 0.0334 | 0.6865 | 0.973 |
Echinococcus multilocularis | tumor protein p63 | 0.0334 | 0.6865 | 0.973 |
Echinococcus multilocularis | geminin | 0.0341 | 0.7025 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0264 | 0.5204 | 0.5166 |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.7025 | 1 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.1105 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.1105 | 0.5 |
Schistosoma mansoni | glutaminase | 0.0264 | 0.5204 | 0.7397 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1105 | 0.1539 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 0.1951 | 0.2747 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0127 | 0.1951 | 0.1428 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0165 | 0.2849 | 0.2946 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1105 | 0.2124 |
Schistosoma mansoni | thyroid hormone receptor | 0.0165 | 0.2849 | 0.4031 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0465 | 1 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.1105 | 0.1034 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.1105 | 0.5 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.1105 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.