Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.2503 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.032 | 0.5 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.032 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.032 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.032 | 0.032 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0081 | 0.2503 | 0.3692 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0081 | 0.2503 | 0.3692 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0054 | 0.0054 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.032 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0054 | 0.0054 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.032 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.2503 | 0.3692 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.1478 | 0.1478 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0779 | 0.0779 |
Echinococcus granulosus | geminin | 0.0188 | 0.6779 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.1478 | 0.1478 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.6779 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0268 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.2503 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.032 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.6779 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.032 | 0.032 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.032 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.032 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0268 | 1 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0054 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.032 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.2503 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.032 | 0.032 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.032 | 0.032 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0779 | 0.0779 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.0054 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0779 | 0.1149 |
Brugia malayi | hypothetical protein | 0.0081 | 0.2503 | 0.2503 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.032 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.032 | 1 |
Echinococcus multilocularis | geminin | 0.0188 | 0.6779 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1478 | 0.1478 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.032 | 0.032 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0054 | 0.139 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.032 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.0054 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.032 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.032 | 0.5 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0081 | 0.2503 | 0.3692 |
Entamoeba histolytica | hypothetical protein | 0.0081 | 0.2503 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.032 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.032 | 0.032 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.1478 | 0.1478 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0054 | 0.0054 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.