Detailed information for compound 817978

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 378.489 | Formula: C18H26N4O3S
  • H donors: 2 H acceptors: 3 LogP: 2.91 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(OCCNC(=O)c1sc2c(c1C)c(NCC1CCCO1)ncn2)C
  • InChi: 1S/C18H26N4O3S/c1-11(2)24-8-6-19-17(23)15-12(3)14-16(21-10-22-18(14)26-15)20-9-13-5-4-7-25-13/h10-11,13H,4-9H2,1-3H3,(H,19,23)(H,20,21,22)
  • InChiKey: KIAMMKBWNZUWDW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0122 0.0165 0.0354
Echinococcus multilocularis voltage dependent calcium channel 0.017 0.0267 0.0256
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0048 0.0011 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Echinococcus multilocularis G-protein coupled receptor, putative 0.0705 0.139 0.1381
Schistosoma mansoni neurotransmitter gated ion channel 0.0122 0.0165 0.0392
Echinococcus multilocularis transient receptor potential cation channel 0.017 0.0267 0.0256
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Schistosoma mansoni vesicular amine transporter 0.0218 0.0368 0.0905
Loa Loa (eye worm) ACC-1 protein 0.0264 0.0464 0.0994
Brugia malayi Protein kinase domain containing protein 0.2265 0.467 1
Echinococcus multilocularis transient receptor potential cation channel 0.017 0.0267 0.0256
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0705 0.139 0.2977
Echinococcus granulosus neuropeptide receptor A26 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0914 0.183 0.392
Echinococcus multilocularis beta tubulin 0.0317 0.0576 0.0565
Trichomonas vaginalis alpha-amylase, putative 0.0125 0.0171 0.2653
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0336 0.0615 0.0605
Brugia malayi Cation transporter family protein 0.0264 0.0464 0.0994
Loa Loa (eye worm) melatonin receptor type 1A 0.0705 0.139 0.2977
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.017 0.0267 0.0649
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.017 0.0267 0.0571
Echinococcus granulosus voltage dependent calcium channel 0.017 0.0267 0.0256
Echinococcus granulosus short transient receptor potential channel 6 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.041 0.0771 0.1652
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Brugia malayi excitatory GABA receptor EXP-1A 0.0264 0.0464 0.0994
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0024
Echinococcus multilocularis GPCR, family 2 0.019 0.0308 0.0298
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0218 0.0368 0.0788
Onchocerca volvulus 0.0705 0.139 0.6113
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Toxoplasma gondii hypothetical protein 0.017 0.0267 0.4535
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Brugia malayi Melatonin receptor type 1A 0.0705 0.139 0.2977
Echinococcus multilocularis nAChR subunit 0.0264 0.0464 0.0454
Trichomonas vaginalis alpha-amylase, putative 0.0111 0.0143 0.2132
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.017 0.0267 0.0649
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0705 0.139 0.1381
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1861 0.3821 0.9647
Echinococcus granulosus g-protein coupled receptor 0.0705 0.139 0.1381
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0315 0.0572 0.0562
Brugia malayi hypothetical protein 0.0122 0.0165 0.0354
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0011 0.0001
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Onchocerca volvulus 0.0264 0.0464 0.2009
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0705 0.139 0.3492
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0142 0.0208 0.0446
Echinococcus multilocularis transient receptor potential cation channel 0.017 0.0267 0.0256
Echinococcus granulosus 7tm_1 domain containing protein 0.0705 0.139 0.1381
Schistosoma mansoni starch branching enzyme II 0.0055 0.0026 0.0038
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Loa Loa (eye worm) neuropeptide F receptor 0.0705 0.139 0.2977
Onchocerca volvulus 0.0154 0.0233 0.0987
Loa Loa (eye worm) hypothetical protein 0.1231 0.2497 0.5347
Onchocerca volvulus 0.0197 0.0323 0.1386
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0142 0.0208 0.0446
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Mycobacterium tuberculosis Conserved hypothetical protein 0.0315 0.0572 0.0633
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0705 0.139 0.3492
Echinococcus multilocularis neuropeptide s receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0142 0.0208 0.05
Echinococcus granulosus tm gpcr rhodopsin 0.0705 0.139 0.1381
Brugia malayi solute carrier family 40, member 1 0.0197 0.0323 0.0693
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.017 0.0267 0.0649
Loa Loa (eye worm) calcium channel 0.017 0.0267 0.0571
Trypanosoma brucei beta tubulin 0.0317 0.0576 1
Brugia malayi ion channel NompC 0.017 0.0267 0.0571
Schistosoma mansoni voltage-gated potassium channel 0.0218 0.0368 0.0905
Schistosoma mansoni voltage-gated potassium channel 0.0218 0.0368 0.0905
Schistosoma mansoni amine GPCR 0.0705 0.139 0.3492
Echinococcus multilocularis alpha 2 macroglobulin 0.0161 0.0249 0.0238
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.017 0.0267 0.0571
Echinococcus granulosus transient receptor potential cation channel 0.017 0.0267 0.0256
Brugia malayi G-protein coupled receptor 0.0705 0.139 0.2977
Onchocerca volvulus 0.0142 0.0208 0.0876
Loa Loa (eye worm) hypothetical protein 0.0197 0.0323 0.0693
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Brugia malayi Dopamine receptor 0.0705 0.139 0.2977
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0073 0.0064 0.0137
Brugia malayi SWIRM domain containing protein 0.0315 0.0572 0.1224
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Onchocerca volvulus 0.0048 0.0011 0.0002
Trichomonas vaginalis alpha-amylase, putative 0.0125 0.0171 0.2653
Onchocerca volvulus 0.0122 0.0165 0.0685
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0336 0.0615 0.0605
Loa Loa (eye worm) integrin beta-2 0.0579 0.1127 0.2413
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.017 0.0267 0.0256
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.017 0.0267 0.0256
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0705 0.139 0.2977
Brugia malayi hypothetical protein 0.0122 0.0165 0.0354
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.019 0.0308 0.066
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Brugia malayi hypothetical protein 0.0315 0.0572 0.1224
Echinococcus granulosus serotonin receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) brahma associated protein 0.0055 0.0025 0.0054
Plasmodium vivax amine transporter, putative 0.0048 0.0011 0.0009
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Schistosoma mansoni tubulin subunit beta 0.0317 0.0576 0.143
Brugia malayi G-protein coupled receptor 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Echinococcus granulosus cyclic nucleotide gated cation channel 0.017 0.0267 0.0256
Trypanosoma brucei beta tubulin 0.0317 0.0576 1
Echinococcus multilocularis shaker cognate 0.0218 0.0368 0.0358
Onchocerca volvulus 0.0048 0.0011 0.0002
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.017 0.0267 0.0571
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0122 0.0165 0.0155
Echinococcus multilocularis neuropeptide receptor A26 0.0705 0.139 0.1381
Echinococcus granulosus neuropeptide receptor 0.0705 0.139 0.1381
Brugia malayi neuropeptide F receptor 0.0705 0.139 0.2977
Echinococcus granulosus Tubulin beta 2C chain 0.0317 0.0576 0.0565
Trichomonas vaginalis alpha-amylase, putative 0.0125 0.0171 0.2653
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0705 0.139 0.1381
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.017 0.0267 0.0256
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Echinococcus multilocularis Tubulin beta 2C chain 0.0317 0.0576 0.0565
Echinococcus multilocularis acetylcholinesterase 0.1861 0.3821 0.3815
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Echinococcus multilocularis g-protein coupled receptor 0.0705 0.139 0.1381
Schistosoma mansoni transient receptor potential channel 4 0.017 0.0267 0.0649
Trichomonas vaginalis tubulin gamma chain, putative 0.0317 0.0576 1
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.1122 0.2268 0.4856
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0315 0.057 0.056
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0218 0.0368 0.0358
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0363 0.0672 0.1673
Brugia malayi hypothetical protein 0.0122 0.0165 0.0354
Schistosoma mansoni alpha-1 adrenergic receptor 0.0705 0.139 0.3492
Loa Loa (eye worm) solute carrier family 6 member 4 0.0285 0.0509 0.109
Mycobacterium ulcerans monoamine oxidase 0.0315 0.0572 0.0588
Onchocerca volvulus 0.0264 0.0464 0.2009
Echinococcus multilocularis integrin beta 2 0.05 0.096 0.095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.019 0.0308 0.0298
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0048 0.0011 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Brugia malayi K+ channel tetramerisation domain containing protein 0.0048 0.0011 0.0023
Schistosoma mansoni neuropeptide receptor 0.1928 0.3961 1
Echinococcus granulosus g protein coupled receptor 0.0705 0.139 0.1381
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0315 0.0572 0.9933
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0705 0.139 0.3492
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Onchocerca volvulus 0.0705 0.139 0.6113
Loa Loa (eye worm) A-macroglobulin complement component family protein 0.0161 0.0249 0.0532
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0218 0.0368 0.0358
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Trypanosoma brucei beta tubulin 0.0317 0.0576 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.0572 0.1224
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0055 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Brugia malayi hypothetical protein 0.017 0.0267 0.0571
Echinococcus granulosus transient receptor potential gamma protein 0.017 0.0267 0.0256
Brugia malayi G protein-coupled receptor 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0336 0.0615 0.1317
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus glycine receptor subunit beta 0.0264 0.0464 0.0454
Schistosoma mansoni two-pore calcium channel 0.017 0.0267 0.0649
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0264 0.0464 0.1148
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0055
Onchocerca volvulus 0.0315 0.057 0.248
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0142 0.0208 0.0446
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0025 0.0261
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0024
Onchocerca volvulus 0.0705 0.139 0.6113
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Toxoplasma gondii alpha amylase, catalytic domain-containing protein 0.0055 0.0026 0.0267
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0218 0.0368 0.0358
Entamoeba histolytica tubulin family protein 0.0317 0.0576 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.0165 0.0354
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0122 0.0165 0.0354
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Schistosoma mansoni tubulin subunit beta 0.0317 0.0576 0.143
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0055 0.0026 0.026
Echinococcus granulosus Tubulin beta 2C chain 0.0317 0.0576 0.0565
Schistosoma mansoni opsin-like receptor 0.0705 0.139 0.3492
Echinococcus granulosus short transient receptor potential channel 6 0.017 0.0267 0.0256
Echinococcus granulosus g protein coupled receptor 0.0705 0.139 0.1381
Brugia malayi Adenylyl cyclase protein 0.0161 0.0248 0.0531
Echinococcus granulosus adenylate cyclase 9 0.0161 0.0248 0.0237
Treponema pallidum sodium- and chloride- dependent transporter 0.0285 0.0509 0.5
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0264 0.0464 0.1148
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0264 0.0464 0.0454
Toxoplasma gondii hypothetical protein 0.0048 0.0011 0.0009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0705 0.139 0.1381
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0572 0.9933
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0055 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Echinococcus multilocularis BC026374 protein (S09 family) 0.0315 0.057 0.056
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Schistosoma mansoni transient receptor potential channel 0.017 0.0267 0.0649
Schistosoma mansoni netrin 0.0063 0.0042 0.0078
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Brugia malayi neuropeptide F receptor 0.0705 0.139 0.2977
Trichomonas vaginalis amylase, putative 0.0125 0.0171 0.2653
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0011 0.0001
Onchocerca volvulus 0.0705 0.139 0.6113
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0142 0.0208 0.0446
Echinococcus granulosus sodium and chloride dependent glycine 0.0048 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus multilocularis SWI:SNF matrix associated 0.0055 0.0025 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis cd109 antigen 0.015 0.0224 0.0214
Brugia malayi Dopamine receptor protein 2 0.0705 0.139 0.2977
Echinococcus granulosus tubulin subunit beta 0.0317 0.0576 0.0565
Brugia malayi hypothetical protein 0.0048 0.0011 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Onchocerca volvulus 0.0705 0.139 0.6113
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Schistosoma mansoni nAChR subunit 0.0122 0.0165 0.0392
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Echinococcus granulosus calcium activated potassium channel 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Onchocerca volvulus Putative nachr subunit 0.0336 0.0615 0.2677
Mycobacterium tuberculosis Possible oxidoreductase 0.0315 0.0572 0.0633
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Brugia malayi brahma associated protein 60 kDa 0.0055 0.0025 0.0054
Echinococcus granulosus transient receptor potential cation channel 0.017 0.0267 0.0256
Echinococcus granulosus neuropeptide Y receptor 0.0705 0.139 0.1381
Echinococcus granulosus neuropeptide FF receptor 2 0.0705 0.139 0.1381
Trichomonas vaginalis tubulin epsilon chain, putative 0.0317 0.0576 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0705 0.139 0.3492
Echinococcus granulosus cyclic nucleotide gated cation channel 0.017 0.0267 0.0256
Echinococcus multilocularis sodium channel protein 0.2028 0.4172 0.4165
Trypanosoma cruzi beta tubulin, putative 0.0317 0.0576 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0264 0.0464 0.0454
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0336 0.0615 0.1317
Echinococcus granulosus two pore calcium channel protein 1 0.017 0.0267 0.0256
Loa Loa (eye worm) carboxylesterase 0.0315 0.057 0.1222
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Onchocerca volvulus 0.0705 0.139 0.6113
Echinococcus granulosus tachykinin peptides receptor 99D 0.0705 0.139 0.1381
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0705 0.139 0.3492
Echinococcus multilocularis potassium voltage gated channel protein 0.0218 0.0368 0.0358
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Echinococcus multilocularis tumor protein p63 0.0345 0.0635 0.0625
Echinococcus multilocularis potassium voltage gated channel protein 0.1231 0.2497 0.2489
Echinococcus multilocularis SWI:SNF matrix associated 0.0055 0.0025 0.0015
Onchocerca volvulus 0.017 0.0267 0.1135
Echinococcus multilocularis fmrfamide receptor 0.0705 0.139 0.1381
Onchocerca volvulus 0.0705 0.139 0.6113
Schistosoma mansoni peptide (allatostatin)-like receptor 0.1122 0.2268 0.5713
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus potassium voltage gated channel subfamily A 0.1231 0.2497 0.2489
Onchocerca volvulus 0.0705 0.139 0.6113
Echinococcus granulosus Tubulin beta 2C chain 0.0317 0.0576 0.0565
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0315 0.057 0.0631
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0315 0.0572 0.142
Onchocerca volvulus 0.0055 0.0025 0.0065
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0048 0.0011 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0705 0.139 0.2977
Schistosoma mansoni opsin-like receptor 0.0705 0.139 0.3492
Echinococcus multilocularis transient receptor potential cation channel 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Toxoplasma gondii beta-1 tubulin, putative 0.0317 0.0576 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0042 0.0089
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0705 0.139 0.1381
Echinococcus granulosus alpha 1A adrenergic receptor 0.0705 0.139 0.1381
Echinococcus granulosus 7TM GPCR rhodopsin 0.0705 0.139 0.1381
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0336 0.0615 0.1317
Trypanosoma cruzi UDP-galactopyranose mutase 0.0315 0.0572 0.9933
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Echinococcus granulosus voltage gated potassium channel 0.0218 0.0368 0.0358
Trichomonas vaginalis tubulin, putative 0.0317 0.0576 1
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.017 0.0267 0.0571
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0016 0.0013
Schistosoma mansoni hypothetical protein 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0705 0.139 0.6113
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0315 0.0572 0.0588
Loa Loa (eye worm) voltage-gated calcium channel 0.017 0.0267 0.0571
Brugia malayi Unc-6 protein precursor 0.0063 0.0042 0.0089
Echinococcus multilocularis serotonin receptor 0.0705 0.139 0.1381
Onchocerca volvulus 0.0063 0.0042 0.0137
Echinococcus granulosus sodium leak channel non selective protein 0.017 0.0267 0.0256
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0315 0.057 0.056
Echinococcus granulosus potassium voltage gated channel protein 0.1231 0.2497 0.2489
Schistosoma mansoni voltage-gated potassium channel 0.0218 0.0368 0.0905
Schistosoma mansoni hypothetical protein 0.019 0.0308 0.0754
Echinococcus granulosus hypothetical protein 0.0705 0.139 0.1381
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.017 0.0267 0.1135
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0102 0.0125 0.0267
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Echinococcus granulosus potassium voltage gated channel subfamily H 0.017 0.0267 0.0256
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.017 0.0267 0.0571
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0315 0.0572 0.1224
Toxoplasma gondii histone lysine-specific demethylase 0.0315 0.0572 0.9933
Brugia malayi brahma associated protein 60 kDa 0.0055 0.0025 0.0054
Schistosoma mansoni hypothetical protein 0.019 0.0308 0.0754
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0705 0.139 0.2977
Echinococcus granulosus potassium voltage gated channel subfamily D 0.017 0.0267 0.0256
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.0165 0.0354
Onchocerca volvulus 0.0705 0.139 0.6113
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.017 0.0267 0.0571
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0705 0.139 0.1381
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0264 0.0464 0.0994
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Echinococcus multilocularis two pore calcium channel protein 2 0.017 0.0267 0.0256
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Schistosoma mansoni hypothetical protein 0.017 0.0267 0.0649
Onchocerca volvulus 0.0048 0.0011 0.0002
Schistosoma mansoni voltage-dependent calcium channel 0.017 0.0267 0.0649
Echinococcus granulosus acetylcholinesterase 0.1861 0.3821 0.3815
Echinococcus granulosus g protein coupled receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Trypanosoma cruzi UDP-galactopyranose mutase 0.0315 0.0572 0.9933
Echinococcus granulosus potassium voltage gated channel protein 0.0218 0.0368 0.0358
Echinococcus multilocularis serotonin transporter 0.0285 0.0509 0.0499
Brugia malayi Carboxylesterase family protein 0.0315 0.057 0.1222
Loa Loa (eye worm) beta-tubulin 0.0317 0.0576 0.1233
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.017 0.0267 0.0571
Echinococcus granulosus glycine receptor subunit beta 0.0264 0.0464 0.0454
Brugia malayi RE15519p 0.0705 0.139 0.2977
Echinococcus multilocularis calcium activated potassium channel 0.017 0.0267 0.0256
Loa Loa (eye worm) acetylcholinesterase 1 0.1861 0.3821 0.8184
Echinococcus multilocularis short transient receptor potential channel 6 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0705 0.139 0.1381
Schistosoma mansoni acetylcholinesterase 0.0315 0.057 0.1417
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Mycobacterium ulcerans oxidoreductase 0.0315 0.0572 0.0588
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0207 0.0196
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0264 0.0464 0.0994
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.017 0.0267 0.0256
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.0048 0.0011 0.0023
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0264 0.0464 0.0454
Brugia malayi Angiotensin-converting enzyme family protein 0.0336 0.0616 0.1318
Echinococcus granulosus SWI:SNF matrix associated 0.0055 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0315 0.057 0.1417
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0122 0.0165 0.0155
Echinococcus multilocularis glycine receptor subunit beta 0.0264 0.0464 0.0454
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.017 0.0267 0.0571
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0446 0.0847 0.3706
Schistosoma mansoni biogenic amine (5HT) receptor 0.0705 0.139 0.3492
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Brugia malayi Carboxylesterase family protein 0.0315 0.057 0.1222
Schistosoma mansoni neurotransmitter gated ion channel 0.0142 0.0208 0.05
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.017 0.0267 0.4389
Schistosoma mansoni opsin-like receptor 0.0705 0.139 0.3492
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0264 0.0464 0.0994
Echinococcus granulosus tumor protein p63 0.0345 0.0635 0.0625
Schistosoma mansoni BC026374 protein (S09 family) 0.0315 0.057 0.1417
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.017 0.0267 0.0571
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Echinococcus granulosus voltage gated hydrogen channel 1 0.017 0.0267 0.0256
Echinococcus granulosus potassium voltage gated channel protein 0.0218 0.0368 0.0358
Brugia malayi K+ channel tetramerisation domain containing protein 0.0048 0.0011 0.0023
Schistosoma mansoni hypothetical protein 0.0705 0.139 0.3492
Echinococcus multilocularis voltage dependent calcium channel 0.017 0.0267 0.0256
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0218 0.0368 0.0358
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0122 0.0165 0.0354
Brugia malayi hypothetical protein 0.0122 0.0165 0.0354
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0264 0.0464 0.0994
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Echinococcus granulosus neuropeptide s receptor 0.0705 0.139 0.1381
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.017 0.0267 0.0649
Toxoplasma gondii glycosyltransferase 0.0055 0.0026 0.0267
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus Tubulin beta 2C chain 0.0317 0.0576 0.0565
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Schistosoma mansoni neuropeptide F-like receptor 0.0705 0.139 0.3492
Leishmania major calcium channel protein, putative,ion transporter, putative 0.2028 0.4172 1
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Schistosoma mansoni nAChR subunit 0.0122 0.0165 0.0392
Leishmania major hypothetical protein, conserved 0.017 0.0267 0.0616
Brugia malayi Serotonin receptor 0.0705 0.139 0.2977
Echinococcus multilocularis voltage gated potassium channel 0.017 0.0267 0.0256
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0264 0.0464 0.1148
Loa Loa (eye worm) carboxylesterase 0.0315 0.057 0.1222
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0055 0.0025 0.0261
Giardia lamblia Beta tubulin 0.0317 0.0576 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0011 0.0001
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0264 0.0464 0.0994
Schistosoma mansoni biogenic amine receptor 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0264 0.0464 0.0454
Loa Loa (eye worm) hypothetical protein 0.0285 0.0509 0.109
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Loa Loa (eye worm) tubulin beta-1 chain 0.0317 0.0576 0.1233
Toxoplasma gondii 1,4-alpha-glucan-branching enzyme 0.0055 0.0026 0.0267
Brugia malayi Carboxylesterase family protein 0.1861 0.3821 0.8184
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0285 0.0509 0.1261
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0122 0.0165 0.0155
Onchocerca volvulus 0.0073 0.0064 0.0235
Echinococcus granulosus BC026374 protein S09 family 0.0315 0.057 0.056
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0264 0.0464 0.0994
Brugia malayi SWIB/MDM2 domain containing protein 0.0055 0.0025 0.0054
Onchocerca volvulus 0.0264 0.0464 0.2009
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0264 0.0464 0.0994
Toxoplasma gondii beta tubulin 0.0317 0.0576 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Schistosoma mansoni hypothetical protein 0.015 0.0224 0.054
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0122 0.0165 0.0155
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Echinococcus granulosus hyperpolarization activated cyclic 0.017 0.0267 0.0256
Schistosoma mansoni ryanodine receptor related 0.017 0.0267 0.0649
Echinococcus multilocularis potassium voltage gated channel protein 0.017 0.0267 0.0256
Schistosoma mansoni hypothetical protein 0.019 0.0308 0.0754
Schistosoma mansoni biogenic amine (5HT) receptor 0.0705 0.139 0.3492
Brugia malayi cation channel family protein 0.017 0.0267 0.0571
Schistosoma mansoni hypothetical protein 0.019 0.0308 0.0754
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Echinococcus multilocularis neuropeptide FF receptor 2 0.0705 0.139 0.1381
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.017 0.0267 0.0256
Echinococcus granulosus neuropeptide Y receptor 0.0705 0.139 0.1381
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0285 0.0509 0.109
Schistosoma mansoni tubulin subunit beta 0.0317 0.0576 0.143
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Schistosoma mansoni gliotactin 0.0315 0.057 0.1417
Echinococcus granulosus hypothetical protein 0.017 0.0267 0.0256
Mycobacterium ulcerans dehydrogenase 0.0315 0.0572 0.0588
Schistosoma mansoni amine GPCR 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis potassium large conductance calcium activated 0.017 0.0267 0.0256
Onchocerca volvulus 0.0122 0.0165 0.0685
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.017 0.0267 0.0571
Brugia malayi Cation transporter family protein 0.0264 0.0464 0.0994
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Trichomonas vaginalis tubulin beta chain, putative 0.0317 0.0576 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0705 0.139 0.2977
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0264 0.0464 0.0994
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.006 0.0035 0.0075
Echinococcus granulosus lysine specific histone demethylase 1A 0.0315 0.0572 0.0562
Loa Loa (eye worm) LGC-31 protein 0.0264 0.0464 0.0994
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0207 0.0442
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Onchocerca volvulus 0.0705 0.139 0.6113
Echinococcus multilocularis Tubulin beta 2C chain 0.0317 0.0576 0.0565
Onchocerca volvulus Neuropeptide F receptor homolog 0.0705 0.139 0.6113
Echinococcus multilocularis allatostatin A receptor 0.1122 0.2268 0.2259
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0705 0.139 0.1381
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.1183 0.2396 0.2387
Loa Loa (eye worm) latrophilin receptor protein 2 0.019 0.0308 0.066
Echinococcus granulosus TRP transient receptor potential channel 0.017 0.0267 0.0256
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0264 0.0464 0.0994
Echinococcus multilocularis beta tubulin 0.0317 0.0576 0.0565
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.416 0.8653 1
Schistosoma mansoni voltage-gated potassium channel 0.0218 0.0368 0.0905
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0264 0.0464 0.0454
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0023
Echinococcus granulosus voltage dependent calcium channel 0.017 0.0267 0.0256
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0048 0.0011 0.0023
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0264 0.0464 0.0454
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.017 0.0267 0.4535
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0315 0.0572 0.9933
Schistosoma mansoni voltage-gated potassium channel 0.1231 0.2497 0.6293
Schistosoma mansoni transient receptor potential channel 0.017 0.0267 0.0649
Brugia malayi Carboxylesterase family protein 0.0315 0.057 0.1222
Schistosoma mansoni brg-1 associated factor 0.0055 0.0025 0.0037
Schistosoma mansoni biogenic amine receptor 0.0705 0.139 0.3492
Echinococcus multilocularis neuropeptide Y receptor 0.0705 0.139 0.1381
Echinococcus multilocularis transient receptor potential gamma protein 0.017 0.0267 0.0256
Chlamydia trachomatis SWIB complex protein 0.0055 0.0025 0.0254
Schistosoma mansoni 60S ribosomal protein L21 0.017 0.0267 0.0649
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0048 0.0011 0.0001
Toxoplasma gondii transporter, cation channel family protein 0.017 0.0267 0.4535
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0705 0.139 0.1381
Mycobacterium ulcerans carboxylesterase, LipT 0.0315 0.057 0.0586
Plasmodium falciparum transporter, putative 0.0048 0.0011 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.0705 0.139 0.1381
Echinococcus granulosus acetylcholinesterase 0.1861 0.3821 0.3815
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Echinococcus multilocularis neuropeptide receptor 0.1928 0.3961 0.3955
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Plasmodium vivax hypothetical protein, conserved 0.0315 0.0572 0.9933
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0048 0.0011 0.0001
Plasmodium falciparum tubulin beta chain 0.0317 0.0576 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0122 0.0165 0.0392
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0705 0.139 0.2977
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0048 0.0011 0.0001
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0315 0.057 0.0631
Schistosoma mansoni voltage-gated potassium channel 0.0218 0.0368 0.0905
Echinococcus granulosus cd109 antigen 0.015 0.0224 0.0214
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0264 0.0464 0.0994
Echinococcus multilocularis hyperpolarization activated cyclic 0.017 0.0267 0.0256
Schistosoma mansoni neuropeptide receptor 0.0705 0.139 0.3492
Echinococcus granulosus peptide allatostatin:somatostatin 0.0705 0.139 0.1381
Brugia malayi Latrophilin receptor protein 2 0.019 0.0308 0.066
Echinococcus multilocularis netrin 1 0.0063 0.0042 0.0031
Brugia malayi GnHR receptor homolog 0.0705 0.139 0.2977
Schistosoma mansoni hypothetical protein 0.0055 0.0025 0.0037
Brugia malayi hypothetical protein 0.0914 0.183 0.392
Brugia malayi hypothetical protein 0.0073 0.0064 0.0137
Plasmodium falciparum protoporphyrinogen oxidase 0.0315 0.0572 0.9933
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Brugia malayi Carboxylesterase family protein 0.1861 0.3821 0.8184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Echinococcus granulosus voltage gated potassium channel 0.017 0.0267 0.0256
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0048 0.0011 0.0001
Toxoplasma gondii transporter, cation channel family protein 0.017 0.0267 0.4535
Trichomonas vaginalis starch branching enzyme II, putative 0.0055 0.0026 0.0006
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0336 0.0616 0.1318
Leishmania major hypothetical protein, unknown function 0.017 0.0267 0.0616
Brugia malayi Transient-receptor-potential like protein 0.017 0.0267 0.0571
Echinococcus granulosus beta tubulin 0.0317 0.0576 0.0565
Toxoplasma gondii hypothetical protein 0.0048 0.0011 0.0009
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.017 0.0267 0.4535
Onchocerca volvulus 0.0705 0.139 0.6113
Onchocerca volvulus 0.0315 0.057 0.248
Toxoplasma gondii hypothetical protein 0.017 0.0267 0.4535
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0705 0.139 0.1381
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.017 0.0267 0.0649
Loa Loa (eye worm) acetyltransferase 0.0141 0.0207 0.0442
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0023
Loa Loa (eye worm) adenylyl cyclase 3 0.0161 0.0248 0.0531
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.017 0.0267 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Trichomonas vaginalis tubulin alpha chain, putative 0.0317 0.0576 1
Echinococcus granulosus nAChR subunit 0.0264 0.0464 0.0454
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.017 0.0267 0.0649
Brugia malayi follicle stimulating hormone receptor 0.0705 0.139 0.2977
Onchocerca volvulus 0.0705 0.139 0.6113
Loa Loa (eye worm) hypothetical protein 0.006 0.0035 0.0075
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Trypanosoma brucei beta tubulin 0.0317 0.0576 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.017 0.0267 0.0571
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.019 0.0308 0.0298
Loa Loa (eye worm) norepinephrine transporter 0.0285 0.0509 0.109
Echinococcus multilocularis glycine receptor subunit beta 0.0264 0.0464 0.0454
Echinococcus multilocularis transient receptor potential cation channel 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0705 0.139 0.3492
Onchocerca volvulus 0.1122 0.2268 1
Schistosoma mansoni acetylcholine receptor-related 0.0122 0.0165 0.0392
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni voltage-gated potassium channel 0.0218 0.0368 0.0905
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0336 0.0615 0.0605
Echinococcus granulosus allatostatin A receptor 0.1122 0.2268 0.2259
Loa Loa (eye worm) tubulin beta chain 0.0317 0.0576 0.1233
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0264 0.0464 0.0994
Echinococcus granulosus Tubulin beta 2C chain 0.0317 0.0576 0.0565
Echinococcus multilocularis neuropeptide Y receptor 0.0705 0.139 0.1381
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0122 0.0165 0.0354
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.017 0.0267 0.0571
Onchocerca volvulus 0.0264 0.0465 0.2013
Echinococcus multilocularis tubulin beta 1 chain 0.0317 0.0576 0.0565
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.017 0.0267 0.0256
Brugia malayi mKIAA0176 protein 0.0048 0.0011 0.0023
Schistosoma mansoni tubulin subunit beta 0.0317 0.0576 0.143
Schistosoma mansoni calcium-activated potassium channel 0.017 0.0267 0.0649
Echinococcus granulosus tubulin beta 4A class IVa 0.0317 0.0576 0.0565
Brugia malayi hypothetical protein 0.0315 0.057 0.1222
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0011 0.0009
Schistosoma mansoni integrin beta subunit 0.0397 0.0744 0.1857
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0009
Trichomonas vaginalis amylase, putative 0.0055 0.0026 0.0006
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0264 0.0464 0.0454
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0705 0.139 0.3492
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Mycobacterium tuberculosis Carboxylesterase LipT 0.0315 0.057 0.0631
Echinococcus multilocularis sodium leak channel non selective protein 0.017 0.0267 0.0256
Brugia malayi Dopamine receptor protein 1 0.0705 0.139 0.2977
Brugia malayi beta-tubulin, identical 0.0317 0.0576 0.1233
Schistosoma mansoni biogenic amine receptor 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0055 0.0025 0.0261
Schistosoma mansoni hypothetical protein 0.01 0.012 0.0278
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Onchocerca volvulus 0.0705 0.139 0.6113
Schistosoma mansoni transient receptor potential channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0264 0.0464 0.0454
Schistosoma mansoni hypothetical protein 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Schistosoma mansoni voltage-gated ion channel 0.017 0.0267 0.0649
Echinococcus multilocularis para nitrobenzyl esterase 0.0315 0.057 0.056
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.017 0.0267 0.0649
Echinococcus multilocularis short transient receptor potential channel 6 0.017 0.0267 0.0256
Echinococcus granulosus neuroligin 0.0315 0.057 0.056
Loa Loa (eye worm) hypothetical protein 0.0161 0.0248 0.0531
Echinococcus multilocularis neuropeptides capa receptor 0.0705 0.139 0.1381
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0336 0.0615 0.0605
Onchocerca volvulus 0.0161 0.0248 0.1051
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0142 0.0208 0.05
Echinococcus multilocularis transfer RNA-Gly 0.0218 0.0368 0.0358
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0264 0.0464 0.0994
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.017 0.0267 0.0256
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0024
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0264 0.0464 0.0454
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.017 0.0267 0.4535
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0122 0.0165 0.0354
Leishmania major UDP-galactopyranose mutase 0.0315 0.0572 0.1349
Echinococcus granulosus glycine receptor subunit alpha 1 0.0264 0.0464 0.0454
Loa Loa (eye worm) voltage-dependent calcium channel 0.017 0.0267 0.0571
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0198 0.0188
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0011 0.0001
Onchocerca volvulus 0.0315 0.057 0.248
Brugia malayi latrophilin 2 splice variant baaae 0.041 0.0771 0.1652
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0264 0.0464 0.0454
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0048 0.0011 0.0023
Schistosoma mansoni voltage-gated cation channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.1861 0.3821 0.8184
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) voltage-gated potassium channel 0.017 0.0267 0.0571
Echinococcus granulosus potassium voltage gated channel protein 0.017 0.0267 0.0256
Schistosoma mansoni histamine h1 receptor 0.0705 0.139 0.3492
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.017 0.0267 0.0571
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.4475 0.9315 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0705 0.139 0.3492
Echinococcus multilocularis g protein coupled receptor 0.0705 0.139 0.1381
Echinococcus granulosus netrin 1 0.0063 0.0042 0.0031
Echinococcus granulosus serotonin transporter 0.0285 0.0509 0.0499
Echinococcus granulosus shaker cognate 0.0218 0.0368 0.0358
Echinococcus granulosus glycine receptor subunit alpha 1 0.0264 0.0464 0.0454
Chlamydia trachomatis protoporphyrinogen oxidase 0.0315 0.0572 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0315 0.057 0.1417
Echinococcus multilocularis tubulin subunit beta 0.0317 0.0576 0.0565
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0264 0.0464 0.0994
Onchocerca volvulus 0.0315 0.057 0.248
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0315 0.0572 0.9933
Echinococcus granulosus transient receptor potential cation channel 0.017 0.0267 0.0256
Loa Loa (eye worm) carboxylesterase 0.1861 0.3821 0.8184
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0317 0.0576 0.0565
Echinococcus granulosus nAChR subunit 0.0142 0.0208 0.0198
Schistosoma mansoni hypothetical protein 0.0055 0.0025 0.0037
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Loa Loa (eye worm) ryanodine receptor 0.017 0.0267 0.0571
Schistosoma mansoni amine GPCR 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Schistosoma mansoni neuropeptide receptor 0.0705 0.139 0.3492
Echinococcus multilocularis Tubulin beta 2C chain 0.0317 0.0576 0.0565
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis potassium voltage gated channel protein 0.0218 0.0368 0.0358
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.017 0.0267 0.0256
Schistosoma mansoni acetylcholine receptor subunit beta 0.0122 0.0165 0.0392
Schistosoma mansoni myosin xvIII 0.0705 0.139 0.3492
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.017 0.0267 0.4535
Schistosoma mansoni amine oxidase 0.0315 0.0572 0.142
Echinococcus multilocularis orexin receptor type 2 0.0705 0.139 0.1381
Loa Loa (eye worm) ion channel NompC 0.017 0.0267 0.0571
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Onchocerca volvulus 0.0264 0.0464 0.2009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.019 0.0308 0.066
Onchocerca volvulus 0.006 0.0035 0.0108
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0705 0.139 0.1381
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0122 0.0165 0.0155
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0218 0.0368 0.0788
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis hyperpolarization activated cyclic 0.017 0.0267 0.0256
Echinococcus multilocularis fmrfamide receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) pigment dispersing factor receptor c 0.06 0.117 0.2506
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0264 0.0464 0.0454
Loa Loa (eye worm) neuropeptide F receptor 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0315 0.0572 0.1224
Echinococcus granulosus fmrfamide receptor 0.0705 0.139 0.1381
Onchocerca volvulus 0.0264 0.0464 0.2009
Echinococcus granulosus two pore calcium channel protein 2 0.017 0.0267 0.0256
Schistosoma mansoni sodium-dependent amino acid transporter 0.0048 0.0011 0.0001
Echinococcus granulosus hyperpolarization activated cyclic 0.017 0.0267 0.0256
Echinococcus multilocularis protoporphyrinogen oxidase 0.0315 0.0572 0.0562
Echinococcus granulosus sodium channel protein 0.2028 0.4172 0.4165
Brugia malayi K+ channel tetramerisation domain containing protein 0.0048 0.0011 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0264 0.0464 0.0994
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus tubulin beta 1 chain 0.0317 0.0576 0.0565
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0264 0.0464 0.0994
Echinococcus multilocularis nAChR subunit 0.0142 0.0208 0.0198
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Brugia malayi hypothetical protein 0.0102 0.0125 0.0267
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.017 0.0267 0.0256
Schistosoma mansoni tubulin subunit beta 0.0317 0.0576 0.143
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Brugia malayi Integrin beta pat-3 precursor 0.0579 0.1127 0.2413
Trypanosoma brucei RNA helicase, putative 0.01 0.012 0.1941
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.017 0.0267 0.0649
Trichomonas vaginalis spcc417.12 protein, putative 0.0315 0.057 0.9907
Echinococcus multilocularis conserved hypothetical protein 0.017 0.0267 0.0256
Echinococcus granulosus sex peptide receptor 0.0705 0.139 0.1381
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Trichomonas vaginalis amylase, putative 0.0125 0.0171 0.2653
Echinococcus granulosus transient receptor potential cation channel 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0705 0.139 0.3492
Brugia malayi larval opioid receptor 0.0705 0.139 0.2977
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0705 0.139 0.2977
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0055 0.0026 0.0015
Trichomonas vaginalis alpha-amylase, putative 0.0125 0.0171 0.2653
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0055 0.0026 0.0015
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Entamoeba histolytica alpha-amylase family protein 0.0125 0.0171 0.2648
Loa Loa (eye worm) GABA receptor subunit 0.0142 0.0208 0.0446
Echinococcus multilocularis sex peptide receptor 0.0705 0.139 0.1381
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0315 0.0572 0.9933
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0264 0.0464 0.0994
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0218 0.0368 0.0358
Onchocerca volvulus 0.0122 0.0165 0.0685
Schistosoma mansoni neuropeptide F-like receptor 0.0705 0.139 0.3492
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.019 0.0308 0.0298
Echinococcus multilocularis neuroligin 0.0315 0.057 0.056
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0264 0.0464 0.0454
Giardia lamblia Beta tubulin 0.0317 0.0576 1
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.4475 0.9315 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Schistosoma mansoni nAChR subunit 0.0264 0.0464 0.1148
Echinococcus multilocularis transient receptor potential cation channel 0.017 0.0267 0.0256
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0264 0.0464 0.1148
Loa Loa (eye worm) hypothetical protein 0.0051 0.0016 0.0034
Loa Loa (eye worm) TYRA-2 protein 0.0705 0.139 0.2977
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0055 0.0025 0.0261
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.0048 0.0011 0.0023
Loa Loa (eye worm) hypothetical protein 0.0315 0.0572 0.1224
Loa Loa (eye worm) G-protein coupled receptor 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.06 0.117 0.2506
Brugia malayi Cation transporter family protein 0.0264 0.0464 0.0994
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus multilocularis G protein coupled receptor 139 0.1928 0.3961 0.3955
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.2265 0.467 1
Echinococcus granulosus G protein coupled receptor 139 0.0705 0.139 0.1381
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.017 0.0267 0.0571
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus transient receptor potential cation channel 0.017 0.0267 0.0256
Echinococcus granulosus potassium large conductance calcium activated 0.017 0.0267 0.0256
Onchocerca volvulus 0.0285 0.0509 0.2207
Echinococcus granulosus orexin receptor type 2 0.0705 0.139 0.1381
Echinococcus multilocularis carboxylesterase 5A 0.1861 0.3821 0.3815
Onchocerca volvulus 0.0264 0.0464 0.2009
Entamoeba histolytica hypothetical protein 0.0142 0.0208 0.332
Echinococcus granulosus neuropeptide receptor 0.1928 0.3961 0.3955
Brugia malayi Carboxylesterase family protein 0.0315 0.057 0.1222
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.017 0.0267 0.0571
Schistosoma mansoni hypothetical protein 0.0055 0.0025 0.0037
Echinococcus granulosus potassium voltage gated channel subfamily H 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus granulosus biogenic amine 5HT receptor 0.0705 0.139 0.1381
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Echinococcus granulosus transient receptor potential cation channel 0.017 0.0267 0.0256
Echinococcus granulosus dro:myosuppressin receptor 0.0705 0.139 0.1381
Schistosoma mansoni amine oxidase 0.0315 0.0572 0.142
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.017 0.0267 0.1135
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0267 0.4535
Echinococcus granulosus ryanodine receptor 44f 0.017 0.0267 0.0256
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Brugia malayi complement component C3-like protein 0.006 0.0035 0.0075
Brugia malayi cation channel family protein 0.017 0.0267 0.0571
Schistosoma mansoni amine GPCR 0.0705 0.139 0.3492
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.017 0.0267 0.0256
Echinococcus granulosus para nitrobenzyl esterase 0.0315 0.057 0.056
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0055 0.0025 0.0261
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Schistosoma mansoni macroglobulin/complement 0.0161 0.0249 0.0602
Toxoplasma gondii transporter, cation channel family protein 0.017 0.0267 0.4535
Loa Loa (eye worm) tubulin beta-2A chain 0.0317 0.0576 0.1233
Onchocerca volvulus 0.0142 0.0208 0.0876
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.1231 0.2497 0.5347
Echinococcus multilocularis adenylate cyclase 9 0.0161 0.0248 0.0237
Schistosoma mansoni sodium/chloride dependent transporter 0.0285 0.0509 0.1261
Schistosoma mansoni neuroligin 3 (S09 family) 0.0315 0.057 0.1417
Echinococcus multilocularis somatostatin receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0705 0.139 0.1381
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Loa Loa (eye worm) hypothetical protein 0.0439 0.0833 0.1783
Onchocerca volvulus 0.0315 0.0572 0.2486
Loa Loa (eye worm) tubulin beta-4 chain 0.0317 0.0576 0.1233
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0264 0.0464 0.0994
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Echinococcus multilocularis dro:myosuppressin receptor 0.0705 0.139 0.1381
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0705 0.139 0.3492
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.4801 1 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0317 0.0576 1
Onchocerca volvulus 0.0705 0.139 0.6113
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.017 0.0267 0.0256
Onchocerca volvulus 0.0051 0.0016 0.0022
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0048 0.0011 0.0001
Echinococcus multilocularis voltage gated potassium channel 0.0218 0.0368 0.0358
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.06 0.117 0.2506
Echinococcus multilocularis ryanodine receptor 44f 0.017 0.0267 0.0256
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0336 0.0615 0.0605
Brugia malayi olfactory channel protein osm-9 0.017 0.0267 0.0571
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus integrin beta 2 0.05 0.096 0.095
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus granulosus rhodopsin orphan GPCR 0.0705 0.139 0.1381
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.017 0.0267 0.4389
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni voltage-gated potassium channel 0.1231 0.2497 0.6293
Loa Loa (eye worm) hypothetical protein 0.0315 0.0572 0.1224
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis g protein coupled receptor 0.0705 0.139 0.1381
Brugia malayi Kelch motif family protein 0.0102 0.0125 0.0267
Onchocerca volvulus 0.0705 0.139 0.6113
Loa Loa (eye worm) serotonin transporter b 0.0285 0.0509 0.109
Loa Loa (eye worm) hypothetical protein 0.0285 0.0509 0.109
Brugia malayi G protein-coupled receptor F59B2.13 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.1861 0.3821 0.8184
Loa Loa (eye worm) BEN-1 protein 0.0317 0.0576 0.1233
Schistosoma mansoni amine GPCR 0.0705 0.139 0.3492
Echinococcus multilocularis voltage gated hydrogen channel 1 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Plasmodium vivax tubulin beta chain, putative 0.0317 0.0576 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0705 0.139 0.2977
Echinococcus multilocularis Tubulin beta 2C chain 0.0317 0.0576 0.0565
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0218 0.0368 0.0358
Schistosoma mansoni neuropeptide f receptor 76f 0.0705 0.139 0.3492
Schistosoma mansoni sodium/chloride dependent transporter 0.0048 0.0011 0.0001
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0048 0.0011 0.0001
Echinococcus granulosus lysine specific histone demethylase 1A 0.0315 0.0572 0.0562
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0055 0.0025 0.0261
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0218 0.0368 0.0358
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Chlamydia trachomatis DNA topoisomerase I 0.0055 0.0025 0.0254
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0705 0.139 0.3492
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0705 0.139 0.3492
Echinococcus multilocularis TRP (transient receptor potential) channel 0.017 0.0267 0.0256
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Loa Loa (eye worm) hypothetical protein 0.0048 0.0011 0.0024
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Brugia malayi A-macroglobulin complement component family protein 0.0161 0.0249 0.0532
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.017 0.0267 0.0649
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.017 0.0267 0.0649
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0102 0.0125 0.0267
Echinococcus multilocularis acetylcholinesterase 0.1861 0.3821 0.3815
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0705 0.139 0.2977
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0218 0.0368 0.0788
Toxoplasma gondii beta-tubulin, putative 0.0317 0.0576 1
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0161 0.0248 0.1051
Schistosoma mansoni hypothetical protein 0.0705 0.139 0.3492
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0264 0.0464 0.1148
Schistosoma mansoni adenoreceptor 0.0705 0.139 0.3492
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0264 0.0464 0.0994
Echinococcus granulosus beta tubulin 0.0317 0.0576 0.0565
Entamoeba histolytica alpha-amylase family protein 0.0125 0.0171 0.2648
Schistosoma mansoni inositol 145-trisphosphate receptor 0.017 0.0267 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0264 0.0464 0.0994
Echinococcus granulosus biogenic amine 5HT receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) acetylcholine receptor protein 0.0122 0.0165 0.0354
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0048 0.0011 0.0023
Brugia malayi ORL1-like opioid receptor 0.0705 0.139 0.2977
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.017 0.0267 0.0256
Echinococcus granulosus neuropeptides capa receptor 0.0705 0.139 0.1381
Brugia malayi Calcitonin receptor-like protein seb-1 0.06 0.117 0.2506
Schistosoma mansoni neuropeptide receptor 0.0705 0.139 0.3492
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis two pore calcium channel protein 1 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.017 0.0267 0.0649
Brugia malayi hypothetical protein 0.0705 0.139 0.2977
Brugia malayi K+ channel tetramerisation domain containing protein 0.0048 0.0011 0.0023
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.2028 0.4172 0.4165
Brugia malayi amine oxidase, flavin-containing family protein 0.0315 0.0572 0.1224
Brugia malayi AKH receptor 0.0705 0.139 0.2977
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0142 0.0208 0.0446
Loa Loa (eye worm) hypothetical protein 0.0315 0.0572 0.1224
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0009
Echinococcus multilocularis neuropeptides capa receptor 0.0705 0.139 0.1381
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0055 0.0026 0.0055
Brugia malayi Serotonin receptor 0.0705 0.139 0.2977
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0315 0.0572 0.142
Loa Loa (eye worm) hypothetical protein 0.0285 0.0509 0.109
Brugia malayi Tubulin beta-1 chain 0.0317 0.0576 0.1233
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus granulosus carboxylesterase 5A 0.1861 0.3821 0.3815
Loa Loa (eye worm) hypothetical protein 0.0315 0.057 0.1222
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0055 0.0025 0.0015
Brugia malayi putative neuropeptide receptor 0.0705 0.139 0.2977
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0264 0.0464 0.1148
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Entamoeba histolytica tubulin family protein 0.0317 0.0576 1
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0048 0.0011 0.0024
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0122 0.0165 0.0354
Echinococcus multilocularis Tubulin beta 2C chain 0.0317 0.0576 0.0565
Loa Loa (eye worm) ACC-1 protein 0.0264 0.0464 0.0994
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0267 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0705 0.139 0.3492
Echinococcus granulosus somatostatin receptor 0.0705 0.139 0.1381
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0122 0.0165 0.0354
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Plasmodium falciparum amino acid transporter, putative 0.0048 0.0011 0.0009
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0264 0.0464 0.0994
Onchocerca volvulus 0.0315 0.057 0.248
Brugia malayi putative neuropeptide receptor NPR1 0.0705 0.139 0.2977
Brugia malayi voltage-dependent calcium channel 0.017 0.0267 0.0571
Schistosoma mansoni hypothetical protein 0.041 0.0771 0.1925
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0264 0.0464 0.0454
Echinococcus multilocularis rhodopsin orphan GPCR 0.0705 0.139 0.1381
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0315 0.0572 0.9933
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0315 0.057 0.9907
Brugia malayi Tachykinin-like peptides receptor 99D 0.0705 0.139 0.2977
Echinococcus granulosus GPCR family 2 0.019 0.0308 0.0298
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0336 0.0615 0.0605
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0705 0.139 0.1381
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0267 0.4535
Echinococcus multilocularis SWI:SNF matrix associated 0.0055 0.0025 0.0015
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.017 0.0267 0.0649
Schistosoma mansoni netrin 0.0063 0.0042 0.0078
Onchocerca volvulus 0.0705 0.139 0.6113
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0207 0.0496
Echinococcus multilocularis g protein coupled receptor 0.0705 0.139 0.1381
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.017 0.0267 0.0571
Brugia malayi sulfakinin receptor protein 0.0914 0.183 0.392
Schistosoma mansoni tubulin subunit beta 0.0317 0.0576 0.143
Echinococcus granulosus potassium voltage gated channel protein 0.017 0.0267 0.0256
Loa Loa (eye worm) hypothetical protein 0.0705 0.139 0.2977
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0705 0.139 0.1381
Brugia malayi hypothetical protein 0.0122 0.0165 0.0354
Echinococcus multilocularis neuropeptide receptor 0.0705 0.139 0.1381
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0315 0.0572 0.5
Loa Loa (eye worm) voltage-gated potassium channel 0.0218 0.0368 0.0788
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0705 0.139 0.2977
Loa Loa (eye worm) hypothetical protein 0.0264 0.0464 0.0994
Loa Loa (eye worm) hypothetical protein 0.017 0.0267 0.0571
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.017 0.0267 0.0256
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.019 0.0308 0.0298
Echinococcus multilocularis serotonin receptor 0.0705 0.139 0.1381
Giardia lamblia Beta tubulin 0.0317 0.0576 1
Leishmania major beta tubulin 0.0317 0.0576 0.1358
Echinococcus multilocularis sodium and chloride dependent glycine 0.0048 0.0011 0.0001
Loa Loa (eye worm) BEN-1 protein 0.0317 0.0576 0.1233
Echinococcus multilocularis 0.0315 0.0572 0.0562

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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