Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0634 | 0.0512 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4393 | 0.4331 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.1152 | 0.1156 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0059 | 0.8265 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0322 | 0.0124 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.1152 | 0.1156 |
Onchocerca volvulus | 0.0034 | 0.4393 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0059 | 0.8265 | 0.8246 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0939 | 0.0892 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.1152 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0059 | 0.8265 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | nuclear receptor | 0.0006 | 0.0222 | 0.0114 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.1152 | 0.1054 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0634 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.8265 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0322 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0322 | 0.0124 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0322 | 0.0124 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0059 | 0.8265 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0322 | 0.0124 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.1152 | 0.1054 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0634 | 0.0512 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.4393 | 0.5186 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0939 | 0.0892 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.1152 | 0.1054 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4678 | 0.4619 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.092 | 0.0867 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.1152 | 0.1156 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.1152 | 0.1054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.1152 | 0.1156 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0059 | 0.8265 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0322 | 0.0215 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | nuclear hormone receptor | 0.0006 | 0.0222 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Onchocerca volvulus | 0.0012 | 0.1152 | 0.2229 | |
Schistosoma mansoni | nuclear receptor | 0.0006 | 0.0222 | 0.0114 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.1152 | 0.1156 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.1152 | 0.1054 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.8265 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0059 | 0.8265 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.4678 | 0.554 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0059 | 0.8265 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.1152 | 0.1054 |
Trichomonas vaginalis | helicase, putative | 0.0008 | 0.0525 | 0.0635 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.4678 | 0.554 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0006 | 0.0222 | 0.0114 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0059 | 0.8265 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0939 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | zinc finger protein | 0.0006 | 0.0222 | 0.0114 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0059 | 0.8265 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4678 | 0.4619 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.4393 | 0.5186 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.1152 | 0.1156 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0059 | 0.8265 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0059 | 0.8265 | 0.5 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0322 | 0.0124 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0322 | 0.0215 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0.1152 | 0.2229 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0006 | 0.0222 | 0.0114 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Brugia malayi | MAP kinase sur-1 | 0.0059 | 0.8265 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.8867 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Schistosoma mansoni | nuclear hormone receptor | 0.0006 | 0.0222 | 0.0114 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.8265 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0322 | 0.0124 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.1152 | 0.1054 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.1152 | 0.1156 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0.1152 | 0.2229 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.1152 | 0.1054 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 0.8265 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Trypanosoma brucei | protein kinase, putative | 0.0059 | 0.8265 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.1152 | 0.1054 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0525 | 0.0635 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.1152 | 0.1054 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0634 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1152 | 0.1156 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.1152 | 0.1156 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0059 | 0.8265 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0059 | 0.8265 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.1152 | 0.1156 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0006 | 0.0222 | 0.0114 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0.1152 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.1152 | 0.1156 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0059 | 0.8265 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0634 | 0.0531 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.1152 | 0.1054 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.1152 | 0.1054 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.0525 | 0.0635 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.