Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | acetylcholinesterase | 0.0271 | 1 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0149 | 0.4577 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0271 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0271 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0271 | 1 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.013 | 0.3738 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0149 | 0.4577 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0149 | 0.4577 | 0.5 |
Onchocerca volvulus | 0.0046 | 0 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0271 | 1 | 1 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0149 | 0.4577 | 0.4577 |
Echinococcus multilocularis | acetylcholinesterase | 0.0271 | 1 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.013 | 0.3738 | 0.3738 |
Onchocerca volvulus | 0.0046 | 0 | 0.5 | |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.013 | 0.3738 | 1 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0149 | 0.4577 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.013 | 0.3738 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 1 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.013 | 0.3738 | 1 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0149 | 0.4577 | 0.4577 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.013 | 0.3738 | 1 |
Onchocerca volvulus | 0.0046 | 0 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0271 | 1 | 1 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.013 | 0.3738 | 0.3738 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0149 | 0.4577 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.013 | 0.3738 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0046 | 0 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.013 | 0.3738 | 0.3738 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.013 | 0.3738 | 1 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0149 | 0.4577 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0149 | 0.4577 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0271 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0046 | 0 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0149 | 0.4577 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0271 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0271 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.013 | 0.3738 | 0.5 |
Onchocerca volvulus | 0.0046 | 0 | 0.5 | |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0149 | 0.4577 | 1 |
Onchocerca volvulus | 0.0046 | 0 | 0.5 | |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0149 | 0.4577 | 0.4577 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0149 | 0.4577 | 0.4577 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.013 | 0.3738 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.