Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.1693 | 0.6656 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0011 | 0.0067 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0011 | 0.0067 | 0.0067 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0068 | 0.2543 | 0.2543 |
Loa Loa (eye worm) | carboxylesterase | 0.0011 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0011 | 0.0067 | 0.0067 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0011 | 0.0067 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2543 | 0.2543 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.2543 | 0.2543 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0011 | 0.0067 | 0.0067 |
Schistosoma mansoni | acetylcholinesterase | 0.0011 | 0.0067 | 0.0265 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0049 | 0.1693 | 1 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0011 | 0.0067 | 0.0265 |
Onchocerca volvulus | 0.0011 | 0.0067 | 0.0398 | |
Brugia malayi | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0011 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0.0067 | 0.5 |
Onchocerca volvulus | 0.0011 | 0.0067 | 0.0398 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.1693 | 0.6656 |
Brugia malayi | follicle stimulating hormone receptor | 0.0236 | 0.9888 | 0.9888 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.2543 | 1 |
Echinococcus multilocularis | neuroligin | 0.0011 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0011 | 0.0067 | 0.0398 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2543 | 0.2543 |
Schistosoma mansoni | gliotactin | 0.0011 | 0.0067 | 0.0265 |
Onchocerca volvulus | 0.0011 | 0.0067 | 0.0398 | |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0011 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0011 | 0.0067 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0068 | 0.2543 | 0.2543 |
Echinococcus multilocularis | acetylcholinesterase | 0.0068 | 0.2543 | 0.2543 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0067 | 0.0265 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0067 | 0.0067 |
Echinococcus multilocularis | acetylcholinesterase | 0.0068 | 0.2543 | 0.2543 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0067 | 0.0067 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.2543 | 0.2543 |
Echinococcus granulosus | carboxylesterase 5A | 0.0068 | 0.2543 | 0.2543 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0236 | 0.9888 | 0.9888 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0067 | 0.0265 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0011 | 0.0067 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | carboxylesterase | 0.0068 | 0.2543 | 0.2543 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0011 | 0.0067 | 0.0067 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.1693 | 0.1693 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0068 | 0.2543 | 0.2543 |
Onchocerca volvulus | 0.0011 | 0.0067 | 0.0398 | |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0011 | 0.0067 | 0.0265 |
Echinococcus granulosus | acetylcholinesterase | 0.0068 | 0.2543 | 0.2543 |
Loa Loa (eye worm) | carboxylesterase | 0.0011 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0067 | 0.0067 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0011 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0.0067 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0067 | 0.0265 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.