Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0142 | 0.6639 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.6639 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0142 | 0.6639 | 0.5 |
Echinococcus granulosus | alkaline phosphatase | 0.017 | 1 | 1 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.017 | 1 | 1 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.017 | 1 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.017 | 1 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.017 | 1 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.017 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.6639 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0142 | 0.6639 | 0.6639 |
Brugia malayi | Carboxylesterase family protein | 0.0142 | 0.6639 | 0.5 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.017 | 1 | 1 |
Echinococcus multilocularis | alkaline phosphatase | 0.017 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0142 | 0.6639 | 0.5 |
Schistosoma mansoni | alkaline phosphatase | 0.017 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.