Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | zinc finger protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0338 | 1 | 1 |
Onchocerca volvulus | 0.0338 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1228 | 0.1228 |
Brugia malayi | nuclear receptor RXR | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0338 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0338 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0179 | 0.5143 | 0.5143 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0338 | 1 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | DR-78 | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0179 | 0.5143 | 0.5143 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0338 | 1 | 1 |
Onchocerca volvulus | 0.016 | 0.4561 | 0.4561 | |
Brugia malayi | nuclear hormone receptor | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0338 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0338 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.016 | 0.4561 | 0.4561 |
Toxoplasma gondii | hypothetical protein | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0179 | 0.5143 | 0.5143 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | nuclear hormone receptor | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0338 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0338 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0338 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1228 | 0.1228 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0338 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0338 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0338 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0179 | 0.5143 | 0.5143 |
Brugia malayi | nuclear receptor RXR | 0.0179 | 0.5143 | 0.5143 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | nuclear hormone receptor | 0.0338 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0179 | 0.5143 | 0.5143 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.1228 | 0.1228 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0338 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0338 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0338 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | nuclear hormone receptor | 0.0338 | 1 | 1 |
Onchocerca volvulus | 0.016 | 0.4561 | 0.4561 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1228 | 0.1228 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0338 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0338 | 1 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0198 | 0.572 | 0.572 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0338 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0338 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0338 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | ecdysone receptor | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0338 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0338 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.1228 | 0.1228 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0338 | 1 | 1 |
Brugia malayi | conserved hypotetical protein | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | steroid hormone receptor | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0179 | 0.5143 | 0.5143 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.1228 | 0.1228 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0338 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0338 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | thyroid hormone receptor | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0338 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0338 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.1228 | 0.1228 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Brugia malayi | tailless protein | 0.016 | 0.4561 | 0.4561 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0338 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1228 | 0.1228 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | FTZ F1 alpha | 0.0338 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0338 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0338 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.5143 | 0.5143 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.1228 | 0.1228 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0338 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0179 | 0.5143 | 0.5143 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.572 | 0.572 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.016 | 0.4561 | 0.4561 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0338 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.016 | 0.4561 | 0.4561 |
Brugia malayi | N-terminal motif family protein | 0.0198 | 0.572 | 0.572 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.016 | 0.4561 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.4561 | 0.4561 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0338 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0338 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0338 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.