TDR Targets

Basic information

Technical information

TDR Targets ID: 820141
Name: methyl 2-[(4-methoxyphenyl)-phenylsulfonylami no]acetate
MW: 335.375 | Formula: C16H17NO5S
H donors: 0 H acceptors: 3 LogP: 2.52 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: COC(=O)CN(S(=O)(=O)c1ccccc1)c1ccc(cc1)OC
InChi: 1S/C16H17NO5S/c1-21-14-10-8-13(9-11-14)17(12-16(18)22-2)23(19,20)15-6-4-3-5-7-15/h3-11H,12H2,1-2H3
InChiKey: NRMCLYAFAKUPIN-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

methyl 2-[(4-methoxyphenyl)-phenylsulfonyl-amino]acetate
2-[(4-methoxyphenyl)-phenylsulfonylamino]acetic acid methyl ester
2-[(4-methoxyphenyl)-phenylsulfonyl-amino]acetic acid methyl ester
methyl 2-[(4-methoxyphenyl)-phenylsulfonyl-amino]ethanoate
BIM-0011251.P001
Oprea1_718483
ZINC00379937
CBMicro_011321
BAS 02180862
[Benzenesulfonyl-(4-methoxy-phenyl)-amino]-acetic acid methyl ester
Oprea1_874440

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	hypothetical protein	0.0049	0.0066	0.0066
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0503	0.2446	0.3924
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	adenoreceptor	0.0105	0.0363	0.0363
Echinococcus multilocularis		0.1531	0.7841	1
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Toxoplasma gondii	sortilin, putative	0.0068	0.0165	0.2088
Onchocerca volvulus		0.0105	0.0363	0.1336
Schistosoma mansoni	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0105	0.0363	0.0462
Loa Loa (eye worm)	TYRA-2 protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	subtilase	0.0091	0.0287	0.0287
Plasmodium vivax	aspartyl proteinase, putative	0.0106	0.0367	0.3872
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0105	0.0363	0.0363
Echinococcus granulosus	7TM GPCR rhodopsin	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Chlamydia trachomatis	protoporphyrinogen oxidase	0.0087	0.0266	0.5
Echinococcus multilocularis	neuropeptide s receptor	0.0551	0.2698	0.3441
Loa Loa (eye worm)	hypothetical protein	0.0123	0.0455	0.0455
Echinococcus granulosus	sex peptide receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0105	0.0363	0.0363
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Schistosoma mansoni	serine/threonine protein kinase	0.0224	0.0985	0.0985
Echinococcus multilocularis	protoporphyrinogen oxidase	0.0087	0.0266	0.0339
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0105	0.0363	0.0462
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Loa Loa (eye worm)	hypothetical protein	0.1943	1	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0138	0.0535	0.0535
Brugia malayi	SWIRM domain containing protein	0.0463	0.224	0.224
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0105	0.0363	0.0462
Echinococcus granulosus	neuropeptide receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	lysine specific histone demethylase 1A	0.0427	0.205	0.2615
Echinococcus multilocularis	serotonin receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	hypothetical protein	0.0105	0.0363	0.0363
Onchocerca volvulus		0.0066	0.0157	0.0387
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Loa Loa (eye worm)	aspartic protease BmAsp-2	0.0106	0.0367	0.0367
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Toxoplasma gondii	peptidase family M13 protein	0.0187	0.0791	1
Toxoplasma gondii	cathepsin CPC2	0.0167	0.0687	0.868
Echinococcus granulosus	neuroendocrine convertase 2	0.1242	0.6325	0.6325
Echinococcus granulosus	tm gpcr rhodopsin	0.1109	0.5628	0.5628
Echinococcus granulosus	endothelin converting enzyme 1	0.0187	0.0791	0.0791
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0091	0.0287	0.0287
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0338	0.1582	0.1582
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0105	0.0363	0.1336
Schistosoma mansoni	neuropeptide F-like receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	c Jun NH2 terminal kinase	0.0224	0.0985	0.1257
Loa Loa (eye worm)	hypothetical protein	0.0427	0.205	0.205
Brugia malayi	amine oxidase, flavin-containing family protein	0.0123	0.0455	0.0455
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0105	0.0363	0.0462
Brugia malayi	Dopamine receptor protein 1	0.0105	0.0363	0.0363
Toxoplasma gondii	subtilisin SUB9	0.0091	0.0287	0.3634
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0105	0.0363	0.0462
Echinococcus granulosus	orexin receptor type 2	0.0105	0.0363	0.0363
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0105	0.0363	0.0363
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	GnHR receptor homolog	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	0.0106	0.0367	0.0486
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0552	0.0552
Brugia malayi	peptidase family M13 containing protein	0.0046	0.0049	0.0049
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1203	0.6121	1
Plasmodium vivax	subtilisin-like serine protease, putative	0.0091	0.0287	0.2346
Trichomonas vaginalis	leucine-rich repeat protein, BspA family	0.0412	0.1969	0.3135
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0138	0.0535	0.0535
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.1109	0.5628	0.7177
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Brugia malayi	hypothetical protein	0.0087	0.0266	0.0266
Echinococcus granulosus	peptidase s8 s53 subtilisin kexin sedolisin	0.0091	0.0287	0.0287
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	follicle stimulating hormone receptor	0.0105	0.0363	0.0363
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.1203	0.6121	0.7806
Loa Loa (eye worm)	neuropeptide F receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus granulosus	c-Jun N-terminal kinases	0.0224	0.0985	0.0985
Echinococcus multilocularis		0.0087	0.0266	0.0339
Trypanosoma brucei	subtilisin peptidase	0.0091	0.0287	1
Brugia malayi	larval opioid receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Loa Loa (eye worm)	endoprotease bli-4	0.1943	1	1
Echinococcus multilocularis	fmrfamide receptor	0.0105	0.0363	0.0462
Brugia malayi	Melatonin receptor type 1A	0.0105	0.0363	0.0363
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0042	0.0029	0.0029
Echinococcus granulosus	neuropeptide FF receptor 2	0.0338	0.1582	0.1582
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0094	0.0305	0.0305
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Leishmania major	UDP-galactopyranose mutase	0.0087	0.0266	0.8981
Schistosoma mansoni	amine oxidase	0.0087	0.0266	0.0266
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.0503	0.2446	0.2446
Trypanosoma cruzi	serine peptidase, clan SB, family S8-like protein	0.0091	0.0287	1
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0713	0.0713
Loa Loa (eye worm)	hypothetical protein	0.0138	0.0535	0.0535
Loa Loa (eye worm)	hypothetical protein	0.0167	0.0687	0.0687
Plasmodium falciparum	plasmepsin IV	0.0106	0.0367	0.3872
Brugia malayi	neuropeptide F receptor	0.0105	0.0363	0.0363
Echinococcus granulosus	neuropeptides capa receptor	0.0105	0.0363	0.0363
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	Serotonin receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	peptidase family M1 containing protein	0.0097	0.0318	0.0318
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0105	0.0363	0.0363
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0094	0.0305	0.0305
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0046	0.0049	0.0049
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Schistosoma mansoni	growth hormone secretagogue receptor	0.0105	0.0363	0.0363
Brugia malayi	G-protein coupled receptor	0.0105	0.0363	0.0363
Brugia malayi	Dopamine receptor protein 2	0.0105	0.0363	0.0363
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Echinococcus granulosus	neuropeptide receptor A26	0.0551	0.2698	0.2698
Mycobacterium ulcerans	proline rich membrane-anchored mycosin MycP5	0.0091	0.0287	0.0416
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0285	0.1306	0.1306
Loa Loa (eye worm)	hypothetical protein	0.0138	0.0535	0.0535
Echinococcus multilocularis	neuropeptide receptor A26	0.0551	0.2698	0.3441
Echinococcus granulosus	neuropeptides capa receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	neuropeptide F-like receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0552	0.0552
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Giardia lamblia	Furin precursor putative serine protease	0.0412	0.1969	0.5557
Brugia malayi	Cyclin, N-terminal domain containing protein	0.005	0.0073	0.0073
Mycobacterium tuberculosis	Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like)	0.0091	0.0287	0.0416
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Echinococcus granulosus	aminopeptidase N	0.012	0.0438	0.0438
Brugia malayi	putative neuropeptide receptor	0.0105	0.0363	0.0363
Echinococcus granulosus	g protein coupled receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus granulosus	Furin 1	0.0503	0.2446	0.2446
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Loa Loa (eye worm)	hypothetical protein	0.005	0.0073	0.0073
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	furin	0.1943	1	1
Mycobacterium ulcerans	membrane-anchored serine protease (mycosin), MycP4	0.0091	0.0287	0.0416
Plasmodium vivax	lysine-specific histone demethylase 1, putative	0.0087	0.0266	0.1927
Schistosoma mansoni	serine-type protease inhibitor	0.1734	0.8901	0.8901
Plasmodium vivax	plasmepsin IV, putative	0.0106	0.0367	0.3872
Onchocerca volvulus		0.0105	0.0363	0.1336
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	fmrfamide receptor	0.0105	0.0363	0.0363
Brugia malayi	Subtilase family protein	0.0091	0.0287	0.0287
Toxoplasma gondii	subtilisin SUB11	0.0091	0.0287	0.3634
Loa Loa (eye worm)	hypothetical protein	0.0187	0.0791	0.0791
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0105	0.0363	0.0363
Plasmodium vivax	hypothetical protein, conserved	0.0087	0.0266	0.1927
Onchocerca volvulus		0.0105	0.0363	0.1336
Brugia malayi	RE15519p	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0266	0.0266
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Brugia malayi	G protein-coupled receptor F59B2.13	0.0105	0.0363	0.0363
Brugia malayi	AKH receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0503	0.2446	0.3924
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Schistosoma mansoni	neprilysin	0.0049	0.0066	0.0066
Trichomonas vaginalis	conserved hypothetical protein	0.0091	0.0287	0.0354
Schistosoma mansoni	amine GPCR	0.0105	0.0363	0.0363
Echinococcus granulosus	g-protein coupled receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	tyrosine kinase	0.0285	0.1306	0.1306
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0503	0.2446	0.3924
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1203	0.6121	1
Echinococcus granulosus	cyclin B	0.005	0.0073	0.0073
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0046	0.0049	0.0049
Onchocerca volvulus		0.0105	0.0363	0.1336
Echinococcus multilocularis	neuropeptides capa receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0187	0.0791	0.0791
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0552	0.0552
Schistosoma mansoni	opsin-like receptor	0.0105	0.0363	0.0363
Onchocerca volvulus		0.012	0.0438	0.1685
Schistosoma mansoni	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0106	0.0367	0.0367
Schistosoma mansoni	amine GPCR	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	neuropeptide receptor	0.0105	0.0363	0.0462
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0105	0.0363	0.0363
Echinococcus multilocularis	G protein coupled receptor 139	0.0105	0.0363	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0107	0.0373	0.0373
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	amine GPCR	0.0105	0.0363	0.0363
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	0.0187	0.0791	0.0791
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Trichomonas vaginalis	conserved hypothetical protein	0.0091	0.0287	0.0354
Mycobacterium leprae	probable zinc metalloprotease	0.0187	0.0791	1
Loa Loa (eye worm)	hypothetical protein	0.0427	0.205	0.205
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	0.0106	0.0367	0.0468
Brugia malayi	Dopamine receptor	0.0105	0.0363	0.0363
Onchocerca volvulus		0.0105	0.0363	0.1336
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Brugia malayi	Stress-activated protein kinase jnk-1	0.0224	0.0985	0.0985
Schistosoma mansoni	neuropeptide f receptor 76f	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0187	0.0791	0.0791
Echinococcus granulosus	neuropeptide s receptor	0.0551	0.2698	0.2698
Echinococcus granulosus	neuropeptide receptor	0.0105	0.0363	0.0363
Brugia malayi	neuroendocrine convertase 1 precursor	0.1242	0.6325	0.6325
Schistosoma mansoni	opsin-like receptor	0.0105	0.0363	0.0363
Brugia malayi	G-protein coupled receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	CMGC/MAPK/JNK protein kinase	0.0224	0.0985	0.0985
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Loa Loa (eye worm)	zinc metallopeptidase 4	0.0046	0.0049	0.0049
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0094	0.0305	0.0305
Echinococcus multilocularis	serotonin receptor	0.0105	0.0363	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase)	0.0046	0.0049	0.0049
Loa Loa (eye worm)	hypothetical protein	0.0338	0.1582	0.1582
Trichomonas vaginalis	neuroendocrine convertase 2 precursor, putative	0.0412	0.1969	0.3135
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Plasmodium vivax	subtilisin-like protease 1	0.0091	0.0287	0.2346
Echinococcus multilocularis	g protein coupled receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	hypothetical protein	0.0049	0.0066	0.0066
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.1203	0.6121	0.6121
Mycobacterium ulcerans	zinc metalloprotease	0.0187	0.0791	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Schistosoma mansoni	serine-type protease inhibitor	0.1734	0.8901	0.8901
Echinococcus granulosus	hypothetical protein	0.0105	0.0363	0.0363
Plasmodium vivax	hypothetical protein, conserved	0.0087	0.0266	0.1927
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0046	0.0049	0.0049
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0105	0.0363	0.0363
Brugia malayi	Hypothetical subtilase-type proteinase F21H12.6 in chromosome II	0.0091	0.0287	0.0287
Loa Loa (eye worm)	hypothetical protein	0.005	0.0073	0.0073
Schistosoma mansoni	biogenic amine receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Plasmodium vivax	subtilisin-like protease 2, putative	0.0091	0.0287	0.2346
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	Lysine-specific histone demethylase 1	0.0427	0.205	0.205
Echinococcus granulosus	g protein coupled receptor	0.0105	0.0363	0.0363
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	0.0187	0.0791	1
Loa Loa (eye worm)	hypothetical protein	0.0138	0.0535	0.0535
Brugia malayi	Serotonin receptor	0.0105	0.0363	0.0363
Onchocerca volvulus		0.0105	0.0363	0.1336
Schistosoma mansoni	neuropeptide receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	amine oxidase	0.0087	0.0266	0.0266
Echinococcus granulosus	allatostatin A receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	hypothetical protein	0.0049	0.0066	0.0066
Echinococcus multilocularis	neuropeptide Y receptor	0.0105	0.0363	0.0462
Echinococcus multilocularis	fmrfamide receptor	0.0105	0.0363	0.0462
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Toxoplasma gondii	histone lysine-specific demethylase	0.0087	0.0266	0.3358
Loa Loa (eye worm)	neuropeptide F receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0552	0.0552
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0049	0.0066	0.0066
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Toxoplasma gondii	aspartyl protease ASP1	0.0106	0.0367	0.464
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0091	0.0287	0.0354
Plasmodium falciparum	plasmepsin VI	0.0106	0.0367	0.3872
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Onchocerca volvulus		0.0105	0.0363	0.1336
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	0.0106	0.0367	0.464
Schistosoma mansoni	hypothetical protein	0.0412	0.1969	0.1969
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Schistosoma mansoni	hypothetical protein	0.0049	0.0066	0.0066
Loa Loa (eye worm)	hypothetical protein	0.074	0.369	0.369
Toxoplasma gondii	subtilisin SUB7	0.0091	0.0287	0.3634
Brugia malayi	sulfakinin receptor protein	0.0105	0.0363	0.0363
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0105	0.0363	0.0363
Echinococcus granulosus	tm gpcr rhodopsin	0.0105	0.0363	0.0363
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0105	0.0363	0.0462
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0105	0.0363	0.0462
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Onchocerca volvulus		0.0093	0.0296	0.103
Plasmodium falciparum	subtilisin-like protease 2	0.0091	0.0287	0.2346
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0105	0.0363	0.1336
Brugia malayi	Cyclin, N-terminal domain containing protein	0.005	0.0073	0.0073
Plasmodium falciparum	plasmepsin V	0.015	0.0597	0.828
Echinococcus multilocularis	g protein coupled receptor	0.0105	0.0363	0.0462
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0105	0.0363	0.0363
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0105	0.0363	0.0462
Plasmodium falciparum	conserved Plasmodium protein, unknown function	0.0087	0.0266	0.1927
Giardia lamblia	High cysteine membrane protein Group 2	0.0701	0.3485	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0105	0.0363	0.0462
Echinococcus granulosus	serotonin receptor	0.0105	0.0363	0.0363
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0105	0.0363	0.0462
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0105	0.0363	0.0462
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0105	0.0363	0.0363
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0167	0.0687	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	Protoporphyrinogen oxidase chloroplast/mitochondrial precursor	0.0087	0.0266	0.0266
Echinococcus multilocularis	epidermal growth factor receptor	0.0285	0.1306	0.1665
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	membrane bound transcription factor site 1	0.0091	0.0287	0.0287
Plasmodium vivax	protoporphyrinogen oxidase, putative	0.0087	0.0266	0.1927
Loa Loa (eye worm)	G-protein coupled receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0266	0.0266
Plasmodium falciparum	protoporphyrinogen oxidase	0.0087	0.0266	0.1927
Echinococcus multilocularis	sex peptide receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	endothelin-converting enzyme-related	0.0046	0.0049	0.0049
Loa Loa (eye worm)	melatonin receptor type 1A	0.0105	0.0363	0.0363
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0338	0.1582	0.2018
Echinococcus multilocularis	sortilin	0.0068	0.0165	0.0211
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0106	0.0367	0.0367
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0091	0.0287	1
Loa Loa (eye worm)	hypothetical protein	0.0084	0.0253	0.0253
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0552	0.0552
Echinococcus multilocularis	aminopeptidase N	0.012	0.0438	0.0559
Echinococcus granulosus	tm gpcr rhodopsin	0.0105	0.0363	0.0363
Onchocerca volvulus		0.0105	0.0363	0.1336
Trichomonas vaginalis	proprotein convertase subtilisin/kexin type, putative	0.0412	0.1969	0.3135
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Echinococcus multilocularis	g-protein coupled receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Echinococcus granulosus	biogenic amine 5HT receptor	0.0105	0.0363	0.0363
Brugia malayi	celfurPC protein	0.1531	0.7841	0.7841
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0105	0.0363	0.0363
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0167	0.0687	1
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0091	0.0287	0.0354
Onchocerca volvulus		0.0105	0.0363	0.1336
Echinococcus multilocularis	orexin receptor type 2	0.0105	0.0363	0.0462
Echinococcus multilocularis	cyclin B	0.005	0.0073	0.0093
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Brugia malayi	Furin-like cysteine rich region family protein	0.0285	0.1306	0.1306
Toxoplasma gondii	subtilisin SUB10	0.0091	0.0287	0.3634
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0105	0.0363	0.0363
Toxoplasma gondii	subtilisin SUB1	0.0091	0.0287	0.3634
Mycobacterium leprae	PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)	0.0091	0.0287	0.0416
Toxoplasma gondii	subtilisin SUB4	0.0091	0.0287	0.3634
Toxoplasma gondii	subtilisin SUB12	0.0091	0.0287	0.3634
Schistosoma mansoni	neprilysin-2 (M13 family)	0.0094	0.0305	0.0305
Onchocerca volvulus		0.0105	0.0363	0.1336
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	0.016	0.0651	0.7335
Schistosoma mansoni	cathepsin D (A01 family)	0.0291	0.1336	0.1336
Brugia malayi	proprotein convertase 2	0.1242	0.6325	0.6325
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0105	0.0363	0.0363
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4)	0.0091	0.0287	0.0416
Echinococcus granulosus	sortilin	0.0068	0.0165	0.0165
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	hypothetical protein	0.0049	0.0066	0.0066
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0503	0.2446	0.3924
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.1943	1	1
Onchocerca volvulus		0.0105	0.0363	0.1336
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0105	0.0363	0.0363
Onchocerca volvulus		0.0463	0.224	1
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0105	0.0363	0.0363
Echinococcus granulosus	7tm_1 domain containing protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	allatostatin A receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Mycobacterium leprae	PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5)	0.0091	0.0287	0.0416
Onchocerca volvulus	CoRest homolog	0.0172	0.0713	0.2952
Brugia malayi	Myb-like DNA-binding domain containing protein	0.0167	0.0687	0.0687
Plasmodium falciparum	subtilisin-like protease 1	0.0091	0.0287	0.2346
Toxoplasma gondii	subtilisin SUB2	0.0091	0.0287	0.3634
Schistosoma mansoni	cyclin B	0.005	0.0073	0.0073
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0087	0.0266	0.8981
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0105	0.0363	0.0363
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0105	0.0363	0.0363
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0427	0.205	0.205
Schistosoma mansoni	Nep2 peptidase (M13 family)	0.0094	0.0305	0.0305
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	g protein coupled receptor	0.0105	0.0363	0.0462
Echinococcus multilocularis	neuropeptides capa receptor	0.0105	0.0363	0.0462
Echinococcus granulosus	somatostatin receptor	0.0105	0.0363	0.0363
Toxoplasma gondii	subtilisin SUB6	0.0091	0.0287	0.3634
Onchocerca volvulus		0.0105	0.0363	0.1336
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0046	0.0049	0.0049
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0138	0.0535	0.0535
Onchocerca volvulus		0.0105	0.0363	0.1336
Schistosoma mansoni	furin-1 (S08 family)	0.0831	0.4166	0.4166
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	putative neuropeptide receptor NPR1	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Trypanosoma cruzi	subtilisin peptidase	0.0091	0.0287	1
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0091	0.0287	1
Schistosoma mansoni	sortilin	0.0048	0.0062	0.0062
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	G-protein coupled receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Echinococcus granulosus	g protein coupled receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus multilocularis	neuroendocrine convertase 2	0.1242	0.6325	0.8066
Brugia malayi	ORL1-like opioid receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	neuropeptide Y receptor	0.0105	0.0363	0.0363
Toxoplasma gondii	subtilisin SUB8	0.0091	0.0287	0.3634
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	opsin-like receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus granulosus	epidermal growth factor receptor	0.0285	0.1306	0.1306
Schistosoma mansoni	neuropeptide receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	amine GPCR	0.0105	0.0363	0.0363
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0091	0.0287	0.0287
Brugia malayi	Membrane-bound transcription factor site-1 protease precursor	0.0091	0.0287	0.0287
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0105	0.0363	0.0363
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Trichomonas vaginalis	hypothetical protein	0.0412	0.1969	0.3135
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0287	0.0287
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0091	0.0287	0.0287
Mycobacterium ulcerans	membrane-anchored mycosin MycP3	0.0091	0.0287	0.0416
Schistosoma mansoni	cathepsin D (A01 family)	0.0291	0.1336	0.1336
Echinococcus multilocularis	Furin 1	0.0503	0.2446	0.312
Echinococcus multilocularis	neuropeptide receptor	0.0105	0.0363	0.0462
Schistosoma mansoni	neuropeptide receptor	0.0105	0.0363	0.0363
Echinococcus granulosus	neuropeptide Y receptor	0.0105	0.0363	0.0363
Entamoeba histolytica	cyclin, putative	0.005	0.0073	0.5
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	Peptidase family M13 containing protein	0.0187	0.0791	0.0791
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0105	0.0363	0.0363
Echinococcus granulosus	rhodopsin orphan GPCR	0.0105	0.0363	0.0363
Mycobacterium leprae	Possible secreted protease	0.0091	0.0287	0.0416
Plasmodium falciparum	subtilisin-like protease 3	0.0091	0.0287	0.2346
Trichomonas vaginalis	conserved hypothetical protein	0.0091	0.0287	0.0354
Echinococcus granulosus	lysine specific histone demethylase 1A	0.0087	0.0266	0.0266
Onchocerca volvulus		0.0105	0.0363	0.1336
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Echinococcus multilocularis	neuropeptide Y receptor	0.0105	0.0363	0.0462
Onchocerca volvulus		0.0091	0.0287	0.0989
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0105	0.0363	0.0462
Echinococcus multilocularis	Peptidase S8 S53, subtilisin kexin sedolisin	0.0091	0.0287	0.0367
Schistosoma mansoni	amine GPCR	0.0105	0.0363	0.0363
Echinococcus multilocularis	membrane bound transcription factor site 1	0.0091	0.0287	0.0367
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0105	0.0363	0.0363
Brugia malayi	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	hypothetical protein	0.0049	0.0066	0.0066
Schistosoma mansoni	tripeptidyl-peptidase II (S08 family)	0.0091	0.0287	0.0287
Echinococcus granulosus	biogenic amine 5HT receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0105	0.0363	0.0462
Toxoplasma gondii	histone lysine-specific demethylase LSD1/BHC110/KDMA1A	0.0087	0.0266	0.3358
Echinococcus multilocularis	endothelin converting enzyme 1	0.0187	0.0791	0.1009
Schistosoma mansoni	myosin xvIII	0.0105	0.0363	0.0363
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Schistosoma mansoni	biogenic amine receptor	0.0105	0.0363	0.0363
Toxoplasma gondii	subtilisin SUB5	0.0091	0.0287	0.3634
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Loa Loa (eye worm)	hypothetical protein	0.0463	0.224	0.224
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0552	0.0552
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Brugia malayi	Peptidase family M1 containing protein	0.012	0.0438	0.0438
Plasmodium falciparum	plasmepsin I	0.0106	0.0367	0.3872
Schistosoma mansoni	histamine h1 receptor	0.0105	0.0363	0.0363
Plasmodium falciparum	lysine-specific histone demethylase 1, putative	0.0087	0.0266	0.1927
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0503	0.2446	0.3924
Trichomonas vaginalis	conserved hypothetical protein	0.0412	0.1969	0.3135
Plasmodium falciparum	plasmepsin II	0.0106	0.0367	0.3872
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Loa Loa (eye worm)	hypothetical protein	0.0187	0.0791	0.0791
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0503	0.2446	0.3924
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus granulosus	G protein coupled receptor 139	0.0105	0.0363	0.0363
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0105	0.0363	0.0363
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0105	0.0363	0.0462
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	0.0106	0.0367	0.0367
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus granulosus	dro:myosuppressin receptor	0.0105	0.0363	0.0363
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3)	0.0091	0.0287	0.0416
Onchocerca volvulus		0.0105	0.0363	0.1336
Mycobacterium ulcerans	epoxide hydrolase EphA	0.016	0.0651	0.7335
Plasmodium vivax	plasmepsin V, putative	0.015	0.0597	0.828
Mycobacterium tuberculosis	Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5)	0.0091	0.0287	0.0416
Loa Loa (eye worm)	hypothetical protein	0.0093	0.0296	0.0296
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Schistosoma mansoni	biogenic amine receptor	0.0105	0.0363	0.0363
Brugia malayi	G protein-coupled receptor	0.0105	0.0363	0.0363
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Schistosoma mansoni	neuropeptide receptor	0.0105	0.0363	0.0363
Echinococcus multilocularis	somatostatin receptor	0.0105	0.0363	0.0462
Brugia malayi	neuropeptide F receptor	0.0105	0.0363	0.0363
Leishmania major	subtilisin-like serine peptidase	0.0091	0.0287	1
Onchocerca volvulus		0.0105	0.0363	0.1336
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0105	0.0363	0.0363
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0105	0.0363	0.0363
Toxoplasma gondii	aspartyl protease ASP5	0.0116	0.042	0.5309
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0091	0.0287	0.0354
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0105	0.0363	0.0363
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0105	0.0363	0.0462
Onchocerca volvulus		0.0105	0.0363	0.1336
Trypanosoma cruzi	UDP-galactopyranose mutase	0.0087	0.0266	0.8981
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0363	0.0363
Loa Loa (eye worm)	proprotein convertase 2	0.0503	0.2446	0.2446
Trypanosoma brucei	serine peptidase, clan SB, family S8-like protein	0.0091	0.0287	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 820141