Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0044 | 0.3031 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0044 | 0.3031 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0124 | 0.9727 | 0.9727 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0044 | 0.3031 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0044 | 0.3031 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0044 | 0.3031 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 1 | 0.5 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0124 | 0.9727 | 0.9727 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0044 | 0.3031 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 1 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 1 | 0.5 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0044 | 0.3031 | 0.3031 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0044 | 0.3031 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0044 | 0.3031 | 0.5 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0044 | 0.3031 | 0.3031 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0044 | 0.3031 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0044 | 0.3031 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0044 | 0.3031 | 0.5 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0044 | 0.3031 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0124 | 0.9727 | 0.9727 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0044 | 0.3031 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0044 | 0.3031 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0044 | 0.3031 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.