Detailed information for compound 821923

Basic information

Technical information
  • TDR Targets ID: 821923
  • Name: 2-(3-fluorophenyl)-3-propyl-1,2-dihydroquinaz olin-4-one
  • MW: 284.328 | Formula: C17H17FN2O
  • H donors: 1 H acceptors: 1 LogP: 3.76 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN1C(Nc2c(C1=O)cccc2)c1cccc(c1)F
  • InChi: 1S/C17H17FN2O/c1-2-10-20-16(12-6-5-7-13(18)11-12)19-15-9-4-3-8-14(15)17(20)21/h3-9,11,16,19H,2,10H2,1H3
  • InChiKey: YTIPRWUPQRIBLV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • BIM-0006141.P001
  • Oprea1_306242
  • Oprea1_637265
  • 2-(3-Fluoro-phenyl)-3-propyl-2,3-dihydro-1H-quinazolin-4-one
  • BAS 02499400
  • CBMicro_006245
  • STOCK2S-13296

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Tubulin alpha 1 chain 0.0027 0.0197 0.0576
Echinococcus multilocularis Tubulin alpha 1 chain 0.0027 0.0197 0.0576
Trypanosoma brucei alpha tubulin 0.0027 0.0197 0.0631
Trichomonas vaginalis tubulin alpha chain, putative 0.0019 0.0002 0.0005
Onchocerca volvulus 0.0092 0.1769 0.311
Echinococcus multilocularis beta tubulin 0.0033 0.0359 0.1054
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Echinococcus multilocularis protein patched 0.006 0.1008 0.2971
Giardia lamblia Beta tubulin 0.0033 0.0359 0.2952
Brugia malayi alpha-tubulin 0.0027 0.0197 0.0438
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.04 0.0779
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.04 0.0779
Trichomonas vaginalis tubulin gamma chain, putative 0.0033 0.0359 0.07
Echinococcus granulosus Tubulin beta 2C chain 0.0033 0.0359 0.1054
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0069 0.1212 0.2362
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Schistosoma mansoni alpha-glucosidase 0.0136 0.2854 0.9219
Echinococcus multilocularis tubulin alpha 3 chain 0.0027 0.0197 0.0576
Schistosoma mansoni alpha tubulin 0.0027 0.0197 0.0631
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Trypanosoma brucei alpha tubulin 0.0027 0.0197 0.0631
Loa Loa (eye worm) BEN-1 protein 0.0033 0.0359 0.0807
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Brugia malayi beta-tubulin, identical 0.0033 0.0359 0.0802
Toxoplasma gondii alpha tubulin TUBA1 0.0027 0.0197 0.4489
Echinococcus multilocularis tubulin subunit beta 0.0033 0.0359 0.1054
Brugia malayi Tubulin alpha-2 chain 0.0027 0.0197 0.0438
Loa Loa (eye worm) alpha-tubulin 0.0027 0.0197 0.0443
Onchocerca volvulus 0.023 0.5132 1
Loa Loa (eye worm) tubulin alpha-2 chain 0.0027 0.0197 0.0443
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0146 0.3095 0.9134
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0197 0.0385
Echinococcus granulosus tubulin alpha 1C chain 0.0027 0.0197 0.0576
Loa Loa (eye worm) hypothetical protein 0.0122 0.2497 0.5607
Plasmodium vivax SET domain protein, putative 0.0029 0.0251 0.6975
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.04 0.0893
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0197 0.0576
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0251 0.0736
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0146 0.3095 1
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0069 0.1212 0.2362
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0146 0.3095 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0027 0.0197 0.0576
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0197 0.0576
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.3388 1
Echinococcus granulosus tubulin alpha chain 0.0027 0.0197 0.0576
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.04 0.0779
Loa Loa (eye worm) alpha-tubulin 0.0027 0.0197 0.0443
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0437 0.0851
Echinococcus granulosus Tubulin beta 2C chain 0.0033 0.0359 0.1054
Giardia lamblia Beta tubulin 0.0033 0.0359 0.2952
Echinococcus multilocularis Tubulin beta 2C chain 0.0033 0.0359 0.1054
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Loa Loa (eye worm) hypothetical protein 0.0029 0.0251 0.0564
Echinococcus granulosus Protein patched homolog 1 0.006 0.1008 0.2971
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Echinococcus multilocularis protein dispatched 1 0.006 0.1008 0.2971
Trypanosoma cruzi alpha tubulin, putative 0.0027 0.0197 0.0631
Giardia lamblia Beta tubulin 0.0033 0.0359 0.2952
Echinococcus granulosus tubulin alpha chain 0.0027 0.0197 0.0576
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.04 0.0779
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0344 0.5
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.04 0.0898
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.04 0.1285
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0069 0.1212 0.2362
Brugia malayi Tubulin beta-1 chain 0.0033 0.0359 0.0802
Schistosoma mansoni tubulin subunit beta 0.0033 0.0359 0.1154
Plasmodium falciparum alpha tubulin 2 0.0027 0.0197 0.5463
Brugia malayi Pre-SET motif family protein 0.0029 0.0251 0.0559
Echinococcus multilocularis Tubulin alpha 1 chain 0.0027 0.0197 0.0576
Echinococcus multilocularis tubulin alpha 1C chain 0.0027 0.0197 0.0576
Echinococcus granulosus Tubulin beta 2C chain 0.0033 0.0359 0.1054
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0226 0.0659
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.04 0.0779
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.4454 1
Loa Loa (eye worm) tubulin alpha chain 0.0027 0.0197 0.0443
Plasmodium vivax tubulin beta chain, putative 0.0033 0.0359 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0344 0.5
Echinococcus multilocularis tubulin beta 1 chain 0.0033 0.0359 0.1054
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.04 0.0779
Loa Loa (eye worm) hypothetical protein 0.006 0.1008 0.2264
Brugia malayi Pre-SET motif family protein 0.0202 0.4454 1
Schistosoma mansoni tubulin subunit alpha 0.0027 0.0197 0.0631
Echinococcus multilocularis Tubulin beta 2C chain 0.0033 0.0359 0.1054
Brugia malayi tubulin alpha-2 chain 0.0027 0.0197 0.0438
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0069 0.1212 1
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Schistosoma mansoni inositol monophosphatase 0.0037 0.0437 0.1405
Trichomonas vaginalis tubulin gamma chain, putative 0.0019 0.0002 0.0005
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.04 0.1285
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0251 0.0736
Trichomonas vaginalis tubulin gamma chain, putative 0.0019 0.0002 0.0005
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.04 0.1174
Loa Loa (eye worm) hypothetical protein 0.0027 0.0197 0.0443
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.006 0.1008 0.2264
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Toxoplasma gondii alpha-tubulin I, putative 0.0027 0.0197 0.4489
Echinococcus granulosus Tubulin beta 2C chain 0.0033 0.0359 0.1054
Echinococcus granulosus tubulin alpha 1C chain 0.0027 0.0197 0.0576
Echinococcus granulosus sterol regulatory element binding protein 0.006 0.1008 0.2971
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0033 0.0359 0.1054
Trichomonas vaginalis tubulin epsilon chain, putative 0.0033 0.0359 0.07
Brugia malayi Tubulin alpha-2 chain 0.0027 0.0197 0.0438
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0197 0.0576
Loa Loa (eye worm) inositol-1 0.0037 0.0437 0.0981
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.3388 0.7608
Schistosoma mansoni alpha-glucosidase 0.0136 0.2854 0.9219
Entamoeba histolytica tubulin alpha chain, putative 0.0027 0.0197 0.4489
Trypanosoma cruzi beta tubulin, putative 0.0033 0.0359 0.1154
Brugia malayi Inositol-1 0.0037 0.0437 0.0976
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0251 0.0805
Echinococcus granulosus beta tubulin 0.0033 0.0359 0.1054
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Echinococcus multilocularis tubulin alpha 1C chain 0.0027 0.0197 0.0576
Loa Loa (eye worm) beta-tubulin 0.0033 0.0359 0.0807
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0146 0.3095 1
Toxoplasma gondii beta-tubulin, putative 0.0033 0.0359 0.8217
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0251 0.0736
Schistosoma mansoni tubulin subunit alpha 0.0027 0.0197 0.0631
Echinococcus granulosus tubulin beta 1 chain 0.0033 0.0359 0.1054
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0251 0.0805
Loa Loa (eye worm) hypothetical protein 0.0122 0.2497 0.5607
Echinococcus granulosus Tubulin alpha 1 chain 0.0027 0.0197 0.0576
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0437 1
Schistosoma mansoni tubulin subunit beta 0.0033 0.0359 0.1154
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0437 1
Giardia lamblia Alpha-tubulin 0.0027 0.0197 0.1612
Echinococcus multilocularis beta tubulin 0.0033 0.0359 0.1054
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0197 0.0385
Echinococcus granulosus tubulin subunit beta 0.0033 0.0359 0.1054
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0437 0.1405
Giardia lamblia Alpha-tubulin 0.0027 0.0197 0.1612
Trypanosoma brucei alpha tubulin 0.0027 0.0197 0.0631
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.3388 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.04 0.1285
Echinococcus multilocularis Tubulin beta 2C chain 0.0033 0.0359 0.1054
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.04 0.915
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0197 0.0385
Loa Loa (eye worm) tubulin beta-1 chain 0.0033 0.0359 0.0807
Brugia malayi tubulin alpha chain - mouse 0.0027 0.0197 0.0438
Echinococcus multilocularis hypothetical protein 0.0027 0.0197 0.0576
Trypanosoma brucei beta tubulin 0.0033 0.0359 0.1154
Trichomonas vaginalis tubulin alpha chain, putative 0.0033 0.0359 0.07
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Toxoplasma gondii beta-1 tubulin, putative 0.0033 0.0359 0.8217
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Schistosoma mansoni tubulin subunit alpha 0.0027 0.0197 0.0631
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.04 0.915
Echinococcus granulosus tubulin alpha chain 0.0027 0.0197 0.0576
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0197 0.0576
Schistosoma mansoni patched 1 0.006 0.1008 0.3252
Trypanosoma brucei beta tubulin 0.0033 0.0359 0.1154
Plasmodium vivax tubulin alpha chain, putative 0.0027 0.0197 0.5463
Schistosoma mansoni inositol monophosphatase 0.0037 0.0437 0.1405
Loa Loa (eye worm) tubulin beta-2A chain 0.0033 0.0359 0.0807
Echinococcus multilocularis Tubulin beta 2C chain 0.0033 0.0359 0.1054
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0197 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.006 0.1008 0.1965
Onchocerca volvulus Huntingtin homolog 0.0122 0.2497 0.4601
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0197 0.0385
Loa Loa (eye worm) tubulin beta chain 0.0033 0.0359 0.0807
Echinococcus granulosus tubulin beta 4A class IVa 0.0033 0.0359 0.1054
Echinococcus granulosus beta tubulin 0.0033 0.0359 0.1054
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0197 0.0385
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0437 0.5
Echinococcus granulosus peroxisome assembly protein 26 0.0027 0.0197 0.0576
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0251 0.0805
Echinococcus multilocularis tubulin subunit TubB 0.0027 0.0197 0.0576
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Echinococcus granulosus Niemann Pick C1 protein 0.006 0.1008 0.2971
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0251 0.5732
Echinococcus multilocularis tubulin alpha 3 chain 0.0027 0.0197 0.0576
Echinococcus multilocularis Niemann Pick C1 protein 0.006 0.1008 0.2971
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0146 0.3095 1
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0146 0.3095 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.3388 1
Entamoeba histolytica tubulin alpha-1 chain 0.0027 0.0197 0.4489
Echinococcus granulosus tubulin alpha chain 0.0027 0.0197 0.0576
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0437 0.1405
Plasmodium falciparum tubulin beta chain 0.0033 0.0359 1
Schistosoma mansoni tubulin subunit beta 0.0033 0.0359 0.1154
Brugia malayi CHE-14 protein 0.006 0.1008 0.226
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0251 0.0805
Loa Loa (eye worm) hypothetical protein 0.0146 0.3095 0.695
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0437 0.1405
Trichomonas vaginalis tubulin beta chain, putative 0.0033 0.0359 0.07
Trichomonas vaginalis tubulin epsilon chain, putative 0.0027 0.0197 0.0385
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.04 0.915
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.04 0.0779
Trichomonas vaginalis tubulin, putative 0.0033 0.0359 0.07
Schistosoma mansoni niemann-pick C1 (NPC1) 0.006 0.1008 0.3252
Echinococcus granulosus tubulin subunit TubB 0.0027 0.0197 0.0576
Trypanosoma brucei glucosidase, putative 0.0035 0.04 0.1285
Plasmodium vivax tubulin alpha chain, putative 0.0027 0.0197 0.5463
Echinococcus granulosus Tubulin alpha 1 chain 0.0027 0.0197 0.0576
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0437 0.1283
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0146 0.3095 0.9134
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.3388 0.7606
Echinococcus granulosus Tubulin beta 2C chain 0.0033 0.0359 0.1054
Trypanosoma brucei beta tubulin 0.0033 0.0359 0.1154
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Echinococcus granulosus alpha tubulin 0.0027 0.0197 0.0576
Trypanosoma brucei alpha tubulin 0.0027 0.0197 0.0631
Echinococcus multilocularis tubulin alpha chain 0.0027 0.0197 0.0576
Schistosoma mansoni tubulin subunit beta 0.0033 0.0359 0.1154
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Loa Loa (eye worm) BEN-1 protein 0.0033 0.0359 0.0807
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0027 0.0197 0.0385
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Loa Loa (eye worm) tubulin beta-4 chain 0.0033 0.0359 0.0807
Echinococcus granulosus tubulin alpha 3 chain 0.0027 0.0197 0.0576
Echinococcus multilocularis Tubulin beta 2C chain 0.0033 0.0359 0.1054
Brugia malayi Tubulin alpha chain 0.0027 0.0197 0.0438
Entamoeba histolytica tubulin family protein 0.0033 0.0359 0.8217
Schistosoma mansoni tubulin subunit beta 0.0033 0.0359 0.1154
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.04 0.0779
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0437 0.0851
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0437 0.1405
Trichomonas vaginalis set domain proteins, putative 0.023 0.5132 1
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0437 0.1283
Echinococcus granulosus tubulin alpha 3 chain 0.0027 0.0197 0.0576
Entamoeba histolytica tubulin family protein 0.0033 0.0359 0.8217
Schistosoma mansoni alpha tubulin 0.0027 0.0197 0.0631
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.04 0.0779
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0437 0.0851
Echinococcus granulosus tubulin alpha chain 0.0027 0.0197 0.0576
Trypanosoma brucei beta tubulin 0.0033 0.0359 0.1154
Plasmodium falciparum alpha tubulin 1 0.0027 0.0197 0.5463
Loa Loa (eye worm) tubulin alpha chain 0.0027 0.0197 0.0443
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0146 0.3095 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.04 0.1174
Leishmania major alpha tubulin 0.0027 0.0197 0.0631
Onchocerca volvulus Huntingtin homolog 0.0122 0.2497 0.4601
Schistosoma mansoni alpha tubulin 0.0027 0.0197 0.0631
Loa Loa (eye worm) tubulin gamma chain 0.0019 0.0002 0.0005
Schistosoma mansoni tubulin subunit beta 0.0033 0.0359 0.1154
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.0197 0.0385
Leishmania major beta tubulin 0.0033 0.0359 0.1154
Brugia malayi hypothetical protein 0.0122 0.2497 0.5604
Trichomonas vaginalis tubulin epsilon chain, putative 0.0033 0.0359 0.07
Toxoplasma gondii beta tubulin 0.0033 0.0359 0.8217
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0146 0.3095 0.6948
Echinococcus multilocularis peroxisome assembly protein 26 0.0027 0.0197 0.0576
Echinococcus multilocularis sterol regulatory element binding protein 0.006 0.1008 0.2971
Schistosoma mansoni alpha glucosidase 0.0035 0.04 0.1285

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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