Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1304 | 0.2757 |
Entamoeba histolytica | cysteine protease, putative | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0329 | 0.4058 | 0.3167 |
Plasmodium vivax | vivapain-1 | 0.0169 | 0.1304 | 0.2757 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0185 | 0.157 | 0.3457 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Onchocerca volvulus | Cathepsin L homolog | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0185 | 0.157 | 0.0306 |
Toxoplasma gondii | cathepsin CPL | 0.0329 | 0.4058 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.022 | 0.218 | 0.1008 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.218 | 0.3182 |
Echinococcus granulosus | cathepsin l1 | 0.0329 | 0.4058 | 0.3167 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.022 | 0.218 | 0.5061 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1304 | 0.2757 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | vivapain-3 | 0.0169 | 0.1304 | 0.2757 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0329 | 0.4058 | 0.4058 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0673 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Onchocerca volvulus | Cathepsin L homolog | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Loa Loa (eye worm) | fibroinase | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.022 | 0.218 | 0.218 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Entamoeba histolytica | cysteine proteinase, putative | 0.022 | 0.218 | 0.3182 |
Trypanosoma brucei | polo-like protein kinase | 0.0185 | 0.157 | 0.0967 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0185 | 0.157 | 0.0306 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0329 | 0.4058 | 0.4058 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0673 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | unspecified product | 0.0169 | 0.1304 | 0.2757 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.218 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0169 | 0.1304 | 0.2757 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0185 | 0.157 | 0.3457 |
Trypanosoma cruzi | cysteine protease, putative | 0.0169 | 0.1304 | 0.2757 |
Plasmodium vivax | vivapain-2 | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.022 | 0.218 | 0.5061 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0185 | 0.157 | 0.157 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.1304 | 0.2757 |
Loa Loa (eye worm) | ctsf protein | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | cathepsin s | 0.0109 | 0.0255 | 0.0255 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0329 | 0.4058 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0185 | 0.157 | 0.3457 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Giardia lamblia | Kinase, PLK | 0.0185 | 0.157 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1304 | 0.2757 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1304 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Echinococcus multilocularis | cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Onchocerca volvulus | 0.022 | 0.218 | 0.2452 | |
Plasmodium vivax | vivapain-2 | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Echinococcus multilocularis | neuropeptide receptor | 0.0673 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Brugia malayi | cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0185 | 0.157 | 0.3457 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.