TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 354.446 | Formula: C20H26N4O2
H donors: 0 H acceptors: 2 LogP: 3.29 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CCCCN(C(=O)C(n1c2ccccc2c2n1c(C)cc(=O)n2)CC)C
InChi: 1S/C20H26N4O2/c1-5-7-12-22(4)20(26)16(6-2)24-17-11-9-8-10-15(17)19-21-18(25)13-14(3)23(19)24/h8-11,13,16H,5-7,12H2,1-4H3
InChiKey: FZTYAVGCXANEQN-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	amine GPCR	0.0052	0.0904	0.1114
Echinococcus granulosus	furin	0.0157	0.5371	1
Schistosoma mansoni	hypothetical protein	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0052	0.0904	0.1114
Echinococcus granulosus	serotonin receptor	0.0052	0.0904	0.1218
Onchocerca volvulus		0.0052	0.0904	0.5
Loa Loa (eye worm)	neuropeptide F receptor	0.0052	0.0904	0.0652
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Echinococcus multilocularis	neuropeptide Y receptor	0.0052	0.0904	0.1632
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Echinococcus multilocularis	neuropeptide receptor	0.0052	0.0904	0.1632
Schistosoma mansoni	furin-1 (S08 family)	0.0068	0.1608	0.1982
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	hypothetical protein	0.0052	0.0904	0.1114
Schistosoma mansoni	opsin-like receptor	0.0052	0.0904	0.1114
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0052	0.0904	0.1218
Echinococcus multilocularis	g protein coupled receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0052	0.0904	0.0652
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0037	0.0285	0.1032
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0052	0.0904	0.0652
Echinococcus multilocularis	G protein coupled receptor 139	0.0052	0.0904	0.1632
Echinococcus granulosus	neuropeptides capa receptor	0.0052	0.0904	0.1218
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.0095	0.2759	0.4865
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus granulosus	allatostatin A receptor	0.0052	0.0904	0.1218
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0052	0.0904	0.1632
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0052	0.0904	0.1114
Echinococcus granulosus	neuropeptide receptor	0.0052	0.0904	0.1218
Echinococcus granulosus	neuropeptides capa receptor	0.0052	0.0904	0.1218
Echinococcus granulosus	tm gpcr rhodopsin	0.0052	0.0904	0.1218
Echinococcus multilocularis	allatostatin A receptor	0.0052	0.0904	0.1632
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0052	0.0904	0.1632
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0052	0.0904	0.1632
Giardia lamblia	High cysteine membrane protein Group 2	0.0058	0.1186	1
Echinococcus multilocularis	serotonin receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	hypothetical protein	0.0222	0.8114	1
Echinococcus granulosus	g protein coupled receptor	0.0052	0.0904	0.1218
Echinococcus granulosus	fmrfamide receptor	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.026	0.9758	0.9973
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Echinococcus granulosus	neuropeptide FF receptor 2	0.0052	0.0904	0.1218
Brugia malayi	Nuclear hormone receptor-like 1	0.0261	0.9783	0.9762
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0052	0.0904	0.1632
Loa Loa (eye worm)	melatonin receptor type 1A	0.0052	0.0904	0.0652
Schistosoma mansoni	biogenic amine receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0157	0.5371	0.6619
Echinococcus granulosus	g protein coupled receptor	0.0052	0.0904	0.1218
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Echinococcus multilocularis	neuropeptides capa receptor	0.0052	0.0904	0.1632
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0095	0.2759	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0052	0.0904	0.1114
Loa Loa (eye worm)	neuropeptide F receptor	0.0052	0.0904	0.0652
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0052	0.0904	0.1114
Onchocerca volvulus		0.0052	0.0904	0.5
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0052	0.0904	0.0652
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0052	0.0904	0.1114
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0052	0.0904	0.1218
Schistosoma mansoni	hypothetical protein	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	serotonin receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Echinococcus granulosus	tm gpcr rhodopsin	0.0052	0.0904	0.1218
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0052	0.0904	0.1114
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	neuropeptide F-like receptor	0.0052	0.0904	0.1114
Echinococcus multilocularis	neuropeptide receptor A26	0.0052	0.0904	0.1632
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0052	0.0904	0.1114
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Loa Loa (eye worm)	TYRA-2 protein	0.0052	0.0904	0.0652
Schistosoma mansoni	amine GPCR	0.0052	0.0904	0.1114
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0052	0.0904	0.5
Loa Loa (eye worm)	G-protein coupled receptor	0.0052	0.0904	0.0652
Schistosoma mansoni	amine GPCR	0.0052	0.0904	0.1114
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0052	0.0904	0.1218
Onchocerca volvulus		0.0052	0.0904	0.5
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	endoprotease bli-4	0.0157	0.5371	0.5354
Echinococcus granulosus	neuroendocrine convertase 2	0.0099	0.2896	0.5135
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0037	0.0285	0.1032
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus granulosus	g-protein coupled receptor	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	growth hormone secretagogue receptor	0.0052	0.0904	0.1114
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.0095	0.2759	0.6515
Echinococcus granulosus	sex peptide receptor	0.0052	0.0904	0.1218
Schistosoma mansoni	neuropeptide receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	myosin xvIII	0.0052	0.0904	0.1114
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0037	0.0285	0.1032
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0037	0.0285	0.1032
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0037	0.0285	0.1032
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	neuropeptide receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	histamine h1 receptor	0.0052	0.0904	0.1114
Brugia malayi	neuroendocrine convertase 1 precursor	0.0099	0.2896	0.219
Echinococcus granulosus	biogenic amine 5HT receptor	0.0052	0.0904	0.1218
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0052	0.0904	0.1114
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0052	0.0904	0.1218
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0052	0.0904	0.1632
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0052	0.0904	0.1632
Echinococcus granulosus	neuropeptide Y receptor	0.0052	0.0904	0.1218
Echinococcus granulosus	hypothetical protein	0.0052	0.0904	0.1218
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	neuropeptide f receptor 76f	0.0052	0.0904	0.1114
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0052	0.0904	0.1114
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0037	0.0285	0.1032
Echinococcus multilocularis	neuropeptide Y receptor	0.0052	0.0904	0.1632
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0052	0.0904	0.1632
Echinococcus multilocularis	neuropeptide s receptor	0.0052	0.0904	0.1632
Echinococcus multilocularis	g-protein coupled receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Echinococcus granulosus	dro:myosuppressin receptor	0.0052	0.0904	0.1218
Echinococcus granulosus	biogenic amine 5HT receptor	0.0052	0.0904	0.1218
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Brugia malayi	proprotein convertase 2	0.0099	0.2896	0.219
Schistosoma mansoni	opsin-like receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	amine GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0052	0.0904	0.1114
Echinococcus multilocularis	fmrfamide receptor	0.0052	0.0904	0.1632
Schistosoma mansoni	opsin-like receptor	0.0052	0.0904	0.1114
Echinococcus multilocularis	dro:myosuppressin receptor	0.0052	0.0904	0.1632
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0095	0.2759	1
Schistosoma mansoni	biogenic amine receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	neuropeptide F-like receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.0037	0.0285	0.0351
Schistosoma mansoni	adenoreceptor	0.0052	0.0904	0.1114
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0052	0.0904	0.1218
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0052	0.0904	0.1114
Echinococcus multilocularis	sex peptide receptor	0.0052	0.0904	0.1632
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Echinococcus multilocularis	neuroendocrine convertase 2	0.0099	0.2896	0.6877
Echinococcus granulosus	neuropeptide s receptor	0.0052	0.0904	0.1218
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus granulosus	7TM GPCR rhodopsin	0.0052	0.0904	0.1218
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus multilocularis	neuropeptides capa receptor	0.0052	0.0904	0.1632
Echinococcus granulosus	neuropeptide Y receptor	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0157	0.5371	0.5354
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0052	0.0904	0.1632
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus granulosus	orexin receptor type 2	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	orexin receptor type 2	0.0052	0.0904	0.1632
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0261	0.9783	1
Loa Loa (eye worm)	hypothetical protein	0.0062	0.1324	0.1094
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0052	0.0904	0.1632
Echinococcus multilocularis	fmrfamide receptor	0.0052	0.0904	0.1632
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0052	0.0904	0.5
Onchocerca volvulus		0.0052	0.0904	0.5
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus granulosus	g protein coupled receptor	0.0052	0.0904	0.1218
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0052	0.0904	0.1114
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis	neuropeptide receptor	0.0052	0.0904	0.1632
Onchocerca volvulus		0.0052	0.0904	0.5
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus multilocularis		0.0127	0.4083	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0052	0.0904	0.1632
Echinococcus multilocularis	g protein coupled receptor	0.0052	0.0904	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	neuropeptide receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0052	0.0904	0.1218
Onchocerca volvulus		0.0052	0.0904	0.5
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus granulosus	neuropeptide receptor A26	0.0052	0.0904	0.1218
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0052	0.0904	0.1632
Schistosoma mansoni	amine GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Brugia malayi	endoprotease bli-4 precursor	0.0157	0.5371	0.491
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	G-protein coupled receptor	0.0052	0.0904	0.0652
Echinococcus granulosus	neuropeptide receptor	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Onchocerca volvulus		0.0052	0.0904	0.5
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0052	0.0904	0.1114
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0052	0.0904	0.1632
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus granulosus	7tm_1 domain containing protein	0.0052	0.0904	0.1218
Echinococcus multilocularis	somatostatin receptor	0.0052	0.0904	0.1632
Onchocerca volvulus		0.0052	0.0904	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Brugia malayi	celfurPC protein	0.0127	0.4083	0.3494
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Brugia malayi	Nuclear hormone receptor-like 1	0.0261	0.9783	0.9762
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Echinococcus granulosus	somatostatin receptor	0.0052	0.0904	0.1218
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Echinococcus granulosus	G protein coupled receptor 139	0.0052	0.0904	0.1218
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0052	0.0904	0.1218
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0052	0.0904	0.1632
Trypanosoma brucei	RNA helicase, putative	0.0222	0.8114	0.5
Echinococcus granulosus	tm gpcr rhodopsin	0.0052	0.0904	0.1218
Echinococcus multilocularis	g protein coupled receptor	0.0052	0.0904	0.1632
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Schistosoma mansoni	hypothetical protein	0.0052	0.0904	0.1114
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0904	0.0652
Onchocerca volvulus		0.0052	0.0904	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0052	0.0904	0.1218
Schistosoma mansoni	neuropeptide receptor	0.0052	0.0904	0.1114
Schistosoma mansoni	biogenic amine receptor	0.0052	0.0904	0.1114

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 823179