Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Echinococcus multilocularis | acetylcholinesterase | 0.1976 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0334 | 0.0903 | 0.0759 |
Brugia malayi | Carboxylesterase family protein | 0.0334 | 0.0903 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1976 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0334 | 0.0903 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0334 | 0.0903 | 0.0759 |
Loa Loa (eye worm) | carboxylesterase | 0.1976 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0334 | 0.0903 | 0.0759 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0334 | 0.0903 | 0.0759 |
Onchocerca volvulus | 0.0334 | 0.0903 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0334 | 0.0903 | 0.0759 |
Onchocerca volvulus | 0.0334 | 0.0903 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0156 | 0.0156 |
Echinococcus granulosus | acetylcholinesterase | 0.1976 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1976 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1976 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0334 | 0.0903 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.1976 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Loa Loa (eye worm) | carboxylesterase | 0.0334 | 0.0903 | 0.0903 |
Schistosoma mansoni | gliotactin | 0.0334 | 0.0903 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Onchocerca volvulus | 0.0334 | 0.0903 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0334 | 0.0903 | 0.0903 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0334 | 0.0903 | 0.5 |
Onchocerca volvulus | 0.0334 | 0.0903 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.1976 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1976 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0334 | 0.0903 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.1976 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0334 | 0.0903 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0334 | 0.0903 | 0.5 |
Onchocerca volvulus | 0.0334 | 0.0903 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0334 | 0.0903 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1976 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0334 | 0.0903 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0334 | 0.0903 | 0.0759 |
Echinococcus multilocularis | acetylcholinesterase | 0.1976 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.0903 | 0.0903 |
Brugia malayi | Carboxylesterase family protein | 0.0334 | 0.0903 | 0.0759 |
Brugia malayi | Carboxylesterase family protein | 0.0334 | 0.0903 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0156 | 0.0156 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.