Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0339 | 0.0901 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0339 | 0.0901 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0339 | 0.0901 | 0.0757 |
Onchocerca volvulus | 0.0339 | 0.0901 | 1 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.2005 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0339 | 0.0901 | 0.0901 |
Brugia malayi | Carboxylesterase family protein | 0.0339 | 0.0901 | 0.0757 |
Echinococcus granulosus | carboxylesterase 5A | 0.2005 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0339 | 0.0901 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0156 | 0.0156 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0339 | 0.0901 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0339 | 0.0901 | 0.0757 |
Onchocerca volvulus | 0.0339 | 0.0901 | 1 | |
Echinococcus granulosus | acetylcholinesterase | 0.2005 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0339 | 0.0901 | 0.0901 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0339 | 0.0901 | 0.5 |
Onchocerca volvulus | 0.0339 | 0.0901 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0339 | 0.0901 | 0.0757 |
Onchocerca volvulus | 0.0339 | 0.0901 | 1 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0339 | 0.0901 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.2005 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0339 | 0.0901 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0156 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2005 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0339 | 0.0901 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0339 | 0.0901 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.2005 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0339 | 0.0901 | 0.0757 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0339 | 0.0901 | 0.0757 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0339 | 0.0901 | 0.0757 |
Loa Loa (eye worm) | carboxylesterase | 0.2005 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0339 | 0.0901 | 0.0757 |
Onchocerca volvulus | 0.0339 | 0.0901 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.2005 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0339 | 0.0901 | 0.0757 |
Echinococcus multilocularis | acetylcholinesterase | 0.2005 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2005 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2005 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.0901 | 0.0901 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2005 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.