Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0025 | 0.0517 | 0.0482 |
Brugia malayi | Carboxylesterase family protein | 0.0146 | 0.4291 | 0.9737 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0517 | 0.1174 |
Echinococcus multilocularis | frizzled | 0.0015 | 0.0212 | 0.0176 |
Schistosoma mansoni | cell adhesion molecule | 0.0012 | 0.013 | 0.0303 |
Echinococcus granulosus | frizzled | 0.0015 | 0.0212 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0036 | 0.0037 |
Echinococcus multilocularis | neuroglian | 0.0012 | 0.011 | 0.0073 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0009 | 0.0036 | 0.0085 |
Loa Loa (eye worm) | carboxylesterase | 0.0025 | 0.0517 | 0.0528 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0036 | 0.0037 |
Echinococcus multilocularis | frizzled 5 | 0.0015 | 0.0212 | 0.0176 |
Echinococcus multilocularis | acetylcholinesterase | 0.0146 | 0.4291 | 0.427 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4291 | 0.4384 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0146 | 0.4291 | 0.427 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.015 | 0.4407 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0146 | 0.4291 | 0.427 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0.0517 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0036 | 0.0037 |
Echinococcus granulosus | frizzled | 0.0015 | 0.0212 | 0.0176 |
Schistosoma mansoni | vesicular amine transporter | 0.0009 | 0.0036 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0036 | 0.0037 |
Echinococcus granulosus | neuroglian | 0.0012 | 0.011 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0025 | 0.0517 | 0.0482 |
Schistosoma mansoni | frizzled-like receptor | 0.0015 | 0.0212 | 0.0494 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0.0517 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0025 | 0.0517 | 0.0482 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0517 | 0.1174 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0025 | 0.0517 | 0.0482 |
Brugia malayi | Frizzled/Smoothened family membrane region containing protein | 0.0015 | 0.0212 | 0.0481 |
Echinococcus granulosus | twitchin | 0.0012 | 0.011 | 0.0073 |
Echinococcus multilocularis | smoothened | 0.033 | 1 | 1 |
Schistosoma mansoni | frizzled-like receptor | 0.0015 | 0.0212 | 0.0494 |
Loa Loa (eye worm) | carboxylesterase | 0.0146 | 0.4291 | 0.4384 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0203 | 0.0207 |
Echinococcus granulosus | frizzled 5 | 0.0015 | 0.0212 | 0.0176 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0025 | 0.0517 | 0.5 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.014 | 0.41 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0009 | 0.0036 | 0.0083 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0025 | 0.0517 | 0.1205 |
Schistosoma mansoni | gliotactin | 0.0025 | 0.0517 | 0.1205 |
Echinococcus multilocularis | frizzled 4 | 0.0015 | 0.0212 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Echinococcus granulosus | acetylcholinesterase | 0.0146 | 0.4291 | 0.427 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0009 | 0.0036 | 0.0085 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.015 | 0.4407 | 0.4502 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0146 | 0.4291 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.013 | 0.0133 |
Brugia malayi | Carboxylesterase family protein | 0.0146 | 0.4291 | 0.9737 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Echinococcus granulosus | frizzled 4 | 0.0015 | 0.0212 | 0.0176 |
Schistosoma mansoni | nephrin | 0.0012 | 0.011 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4291 | 0.4384 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.9788 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0025 | 0.0517 | 0.1205 |
Echinococcus multilocularis | frizzled | 0.0015 | 0.0212 | 0.0176 |
Echinococcus multilocularis | neuroligin | 0.0025 | 0.0517 | 0.0482 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0517 | 0.1174 |
Loa Loa (eye worm) | frizzled/Smoothened family membrane region containing protein | 0.0015 | 0.0212 | 0.0216 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0025 | 0.0517 | 0.0482 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0025 | 0.0517 | 0.5 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0036 | 0.0083 |
Echinococcus granulosus | frizzled | 0.0015 | 0.0212 | 0.0176 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0146 | 0.4291 | 0.4384 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0517 | 0.1205 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0025 | 0.0517 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Echinococcus granulosus | acetylcholinesterase | 0.0146 | 0.4291 | 0.427 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0025 | 0.0517 | 0.5 |
Loa Loa (eye worm) | frizzled/Smoothened family membrane region containing protein | 0.0015 | 0.0212 | 0.0216 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0517 | 0.1205 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0036 | 0.0037 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0517 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0036 | 0.0037 |
Echinococcus multilocularis | frizzled 10 | 0.0015 | 0.0212 | 0.0176 |
Loa Loa (eye worm) | carboxylesterase | 0.0025 | 0.0517 | 0.0528 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0025 | 0.0517 | 0.1205 |
Echinococcus multilocularis | acetylcholinesterase | 0.0146 | 0.4291 | 0.427 |
Echinococcus granulosus | roundabout 2 | 0.0015 | 0.0203 | 0.0167 |
Brugia malayi | Carboxylesterase family protein | 0.0025 | 0.0517 | 0.1174 |
Brugia malayi | Frizzled/Smoothened family membrane region containing protein | 0.0015 | 0.0212 | 0.0481 |
Schistosoma mansoni | frizzled | 0.0015 | 0.0212 | 0.0494 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0025 | 0.0517 | 0.0482 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0009 | 0.0036 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0517 | 0.0528 |
Echinococcus multilocularis | roundabout 2 | 0.0015 | 0.0203 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0203 | 0.0207 |
Schistosoma mansoni | acetylcholinesterase | 0.0025 | 0.0517 | 0.1205 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0012 | 0.013 | 0.0094 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0025 | 0.0517 | 0.5 |
Onchocerca volvulus | 0.0137 | 0.4001 | 0.9723 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.