Detailed information for compound 824079

Basic information

Technical information
  • TDR Targets ID: 824079
  • Name: ethyl 5-[(4-ethoxyphenyl)carbamoylamino]-2,4- dimethyl-1H-pyrrole-3-carboxylate
  • MW: 345.393 | Formula: C18H23N3O4
  • H donors: 3 H acceptors: 2 LogP: 2.75 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)NC(=O)Nc1[nH]c(c(c1C)C(=O)OCC)C
  • InChi: 1S/C18H23N3O4/c1-5-24-14-9-7-13(8-10-14)20-18(23)21-16-11(3)15(12(4)19-16)17(22)25-6-2/h7-10,19H,5-6H2,1-4H3,(H2,20,21,23)
  • InChiKey: UJPRCIZTKWOCKP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[[[(4-ethoxyphenyl)amino]-oxomethyl]amino]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester
  • 5-[(4-ethoxyphenyl)carbamoylamino]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.005 0.0071
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.011 0.113 0.113
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.002 0.005 0.0071
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0053 0.0128
Trichomonas vaginalis DNA polymerase II, putative 0.0138 0.1459 0.3549
Brugia malayi hypothetical protein 0.0056 0.0483 0.0682
Echinococcus granulosus carboxylesterase 5A 0.0146 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.011 0.1129 0.1593
Echinococcus multilocularis thyroid hormone receptor alpha 0.0231 0.2572 0.2572
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0137 0.0334
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0106 0.108 0.108
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0051 0.0123
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0326 0.0326
Brugia malayi Pre-SET motif family protein 0.0031 0.0189 0.0266
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0051 0.0123
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0189 0.0189
Echinococcus multilocularis carbonic anhydrase 0.0082 0.0789 0.0789
Onchocerca volvulus 0.002 0.005 0.0123
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0053 0.0128
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0137 0.0334
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.1306 0.1306
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0419 0.1018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.1441 0.1441
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0129 0.1354 0.3294
Onchocerca volvulus 0.0025 0.0108 0.0263
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0085 0.0824 0.0824
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0189 0.0189
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0051 0.0071
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0051 0.0123
Loa Loa (eye worm) hypothetical protein 0.0108 0.1097 0.1549
Echinococcus multilocularis nervana 2 0.0068 0.0624 0.0624
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0731 0.6008
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0014 0.0035
Toxoplasma gondii hypothetical protein 0.0082 0.0789 0.192
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0006 0.0006
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0106 0.108 0.108
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.1624 0.2292
Trichomonas vaginalis spcc417.12 protein, putative 0.0025 0.0108 0.0263
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0106 0.108 0.1524
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Echinococcus multilocularis protein patched 0.0088 0.0862 0.0862
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0106 0.108 0.1524
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Brugia malayi laminin alpha chain 0.0025 0.0118 0.0166
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0051 0.0123
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0205 0.2254 0.3181
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0731 0.1032
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0326 0.0792
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0106 0.108 0.1524
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0247 0.0247
Brugia malayi Carboxylesterase family protein 0.0025 0.0108 0.0152
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0106 0.108 0.108
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0326 0.0792
Schistosoma mansoni transcription factor btf3 0.0037 0.0255 0.0255
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0049 0.0049
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0189 0.0189
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.005 0.0412 0.0412
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.1441 0.1441
Loa Loa (eye worm) ACC-1 protein 0.002 0.005 0.0071
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0106 0.108 0.108
Echinococcus granulosus expressed conserved protein 0.0192 0.2106 0.2106
Onchocerca volvulus 0.002 0.005 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0326 0.0792
Echinococcus multilocularis protein dispatched 1 0.01 0.101 0.101
Echinococcus multilocularis nervana 2 0.011 0.113 0.113
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0014 0.002
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0066 0.0605 0.1471
Schistosoma mansoni intermediate filament proteins 0.0111 0.1142 0.1142
Echinococcus multilocularis pikachurin 0.0025 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0125 0.1306 0.1306
Loa Loa (eye worm) hypothetical protein 0.0238 0.265 0.374
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.8087 0.8087
Schistosoma mansoni nuclear hormone receptor 0.005 0.0412 0.0412
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0051 0.0123
Echinococcus multilocularis BC026374 protein (S09 family) 0.0025 0.0108 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.3066 0.7456
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.002 0.005 0.005
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0025 0.0118 0.0166
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.1217 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.1217 1
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.012 0.124 0.3016
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0106 0.108 0.108
Echinococcus multilocularis carbonic anhydrase 0.0082 0.0789 0.0789
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0731 0.1778
Echinococcus multilocularis Niemann Pick C1 protein 0.0205 0.2254 0.2254
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0051 0.0123
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0326 0.0326
Echinococcus granulosus transcription factor btf3 0.0037 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.011 0.1129 0.1593
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0129 0.1354 0.3294
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Echinococcus granulosus acetylcholinesterase 0.0146 0.1549 0.1549
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0326 0.0326
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0731 0.1778
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0006 0.0006
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0455 0.0455
Echinococcus granulosus Niemann Pick C1 protein 0.0293 0.3301 0.3301
Echinococcus granulosus lamin 0.0111 0.1142 0.1142
Loa Loa (eye worm) hypothetical protein 0.0056 0.0483 0.0682
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0205 0.2254 0.5482
Echinococcus multilocularis GPCR, family 2 0.0048 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Loa Loa (eye worm) DR-78 0.005 0.0412 0.0581
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0051 0.0123
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0053 0.0053
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0056 0.0483 0.0483
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0137 0.0334
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0731 0.1778
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0483 0.0682
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0106 0.108 0.1524
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Echinococcus granulosus BC026374 protein S09 family 0.0025 0.0108 0.0108
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0129 0.1354 0.3294
Loa Loa (eye worm) hypothetical protein 0.0152 0.1624 0.2292
Loa Loa (eye worm) hypothetical protein 0.0082 0.0789 0.1114
Echinococcus granulosus nervana 2 0.0068 0.0624 0.0624
Brugia malayi Cation transporter family protein 0.002 0.005 0.0071
Entamoeba histolytica hypothetical protein 0.0037 0.0255 0.0621
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0053 0.0074
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0129 0.1354 0.1911
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0483 0.0483
Schistosoma mansoni patched 1 0.0088 0.0862 0.0862
Trichomonas vaginalis cdc25b, putative 0.012 0.124 0.3016
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.002 0.005 0.0071
Schistosoma mansoni nuclear receptor 0.005 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Schistosoma mansoni hypothetical protein 0.0085 0.0824 0.0824
Echinococcus multilocularis jun protein 0.0082 0.0797 0.0797
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0389 0.4445 0.4445
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0387 0.0547
Brugia malayi hypothetical protein 0.0164 0.1772 0.25
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Echinococcus granulosus jun protein 0.0082 0.0797 0.0797
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0129 0.1354 0.1354
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0129 0.1354 0.3294
Brugia malayi hypothetical protein 0.0238 0.265 0.374
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.002 0.005 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0106 0.108 0.1524
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0014 0.0035
Brugia malayi Steroid receptor seven-up type 2 0.0106 0.108 0.1524
Echinococcus multilocularis nervana 2 0.011 0.113 0.113
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.162 0.2286
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0731 0.0731
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0051 0.0051
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.265 0.265
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.011 0.1122 0.1584
Loa Loa (eye worm) hypothetical protein 0.0104 0.1051 0.1484
Onchocerca volvulus 0.0031 0.0189 0.0459
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.005 0.0071
Brugia malayi follicle stimulating hormone receptor 0.0252 0.2818 0.3978
Echinococcus granulosus bloom syndrome protein 0.002 0.0053 0.0053
Brugia malayi nuclear receptor NHR-88 0.005 0.0412 0.0581
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0082 0.0789 0.1114
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0118 0.0118
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0483 0.0682
Toxoplasma gondii DNA polymerase family B protein 0.0129 0.1354 0.3294
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0361 0.4112 1
Echinococcus granulosus para nitrobenzyl esterase 0.0025 0.0108 0.0108
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0255 0.0621
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Loa Loa (eye worm) nuclear receptor nhr-7B 0.005 0.0412 0.0581
Trypanosoma brucei protein kinase, putative 0.0051 0.0419 0.1018
Loa Loa (eye worm) acetylcholinesterase 1 0.0146 0.1549 0.2186
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.002 0.005 0.0071
Echinococcus multilocularis lamin dm0 0.0111 0.1142 0.1142
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0014 0.002
Schistosoma mansoni hypothetical protein 0.0082 0.0789 0.0789
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0129 0.1354 0.1354
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0106 0.108 0.108
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0106 0.108 0.1524
Loa Loa (eye worm) hypothetical protein 0.0109 0.1118 0.1578
Echinococcus granulosus nuclear receptor 2DBD gamma 0.005 0.0412 0.0412
Echinococcus multilocularis Niemann Pick C1 protein 0.0293 0.3301 0.3301
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0068 0.0624 0.0624
Schistosoma mansoni carbonic anhydrase-related 0.0082 0.0789 0.0789
Giardia lamblia DNA polymerase alpha subunit A 0.0097 0.0974 0.2369
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0106 0.108 0.108
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Toxoplasma gondii DNA polymerase family B protein 0.0057 0.05 0.1216
Echinococcus granulosus nuclear receptor nhr 48 0.005 0.0412 0.0412
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0129 0.1354 0.3294
Schistosoma mansoni lamin 0.0111 0.1142 0.1142
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.012 0.124 0.3016
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0051 0.0123
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0326 0.0326
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0051 0.0123
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0247 0.0348
Echinococcus granulosus nervana 2 0.011 0.113 0.113
Brugia malayi Niemann-Pick C1 protein precursor 0.0205 0.2254 0.3181
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0731 0.1778
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0361 0.4112 0.5803
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0051 0.0123
Loa Loa (eye worm) hypothetical protein 0.0025 0.0118 0.0166
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0255 0.0621
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.002 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.0072 0.0669 0.0945
Brugia malayi conserved hypotetical protein 0.005 0.0412 0.0581
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0047 0.0066
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0051 0.0123
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0419 0.0419
Brugia malayi Carboxylesterase family protein 0.0146 0.1549 0.2186
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1441 0.1441
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0419 0.1018
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0106 0.108 0.1524
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.011 0.113 0.113
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.002 0.0051 0.0051
Echinococcus granulosus cpg binding protein 0.0063 0.0571 0.0571
Brugia malayi hypothetical protein 0.0027 0.0137 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0419 0.0419
Brugia malayi nuclear receptor NHR-67 0.005 0.0412 0.0581
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0057 0.05 0.0705
Brugia malayi DNA polymerase delta catalytic subunit 0.0361 0.4112 0.5803
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0118 0.1217 0.2959
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.005 0.005
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.002 0.005 0.005
Echinococcus granulosus thyroid hormone receptor alpha 0.005 0.0412 0.0412
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0326 0.0326
Echinococcus granulosus glycine receptor subunit beta 0.002 0.005 0.005
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.1441 0.2033
Brugia malayi beta-NAC-like protein 0.0037 0.0255 0.036
Schistosoma mansoni hypothetical protein 0.0192 0.21 0.21
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0106 0.108 0.1524
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0051 0.0123
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.005 0.0071
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0053 0.0128
Schistosoma mansoni hypothetical protein 0.0048 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0419 0.0419
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.1051 0.1484
Schistosoma mansoni hypothetical protein 0.0049 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.012 0.124 0.175
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.005 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.002 0.005 0.005
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0419 0.1018
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0106 0.108 0.108
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.005 0.0071
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0419 0.0591
Brugia malayi Rhodanese-like domain containing protein 0.012 0.124 0.175
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0862 0.2096
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0412 0.1002
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0731 0.1778
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.2063 0.5017
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.002 0.005 0.005
Trichomonas vaginalis cdc25b, putative 0.012 0.124 0.3016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1441 0.1441
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0419 0.1018
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0051 0.0123
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0419 0.1018
Loa Loa (eye worm) hypothetical protein 0.0123 0.1284 0.1812
Onchocerca volvulus 0.012 0.124 0.3016
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.1217 0.1217
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.3066 0.7456
Brugia malayi Cation transporter family protein 0.002 0.005 0.0071
Schistosoma mansoni hypothetical protein 0.0104 0.1051 0.1051
Echinococcus granulosus carbonic anhydrase 0.0082 0.0789 0.0789
Brugia malayi hypothetical protein 0.0025 0.0108 0.0152
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0138 0.1459 0.3549
Echinococcus granulosus single minded 2 0.0036 0.0247 0.0247
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.1441 0.1441
Echinococcus multilocularis FTZ F1 alpha 0.0106 0.108 0.108
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0174 0.1889 0.4595
Schistosoma mansoni carbonic anhydrase-related 0.0082 0.0789 0.0789
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.008 0.0768 0.6308
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0106 0.108 0.1524
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1441 0.1441
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.3066 0.7456
Loa Loa (eye worm) hypothetical protein 0.0262 0.2938 0.4146
Schistosoma mansoni coup transcription factor 0.0106 0.108 0.108
Loa Loa (eye worm) carboxylesterase 0.0146 0.1549 0.2186
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0051 0.0071
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0106 0.108 0.108
Onchocerca volvulus DNA polymerase homolog 0.0129 0.1354 0.3294
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0051 0.0123
Loa Loa (eye worm) hypothetical protein 0.0025 0.0118 0.0166
Brugia malayi MAP kinase sur-1 0.0051 0.0419 0.0591
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Loa Loa (eye worm) hypothetical protein 0.0054 0.0455 0.0643
Loa Loa (eye worm) hypothetical protein 0.0164 0.1772 0.25
Loa Loa (eye worm) hypothetical protein 0.0146 0.1549 0.2186
Echinococcus multilocularis carbonic anhydrase 0.0082 0.0789 0.0789
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.005 0.0071
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0129 0.1354 0.1354
Echinococcus granulosus nervana 2 0.011 0.113 0.113
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0053 0.0128
Echinococcus granulosus intermediate filament protein 0.0111 0.1142 0.1142
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0189 0.0266
Schistosoma mansoni hypothetical protein 0.0085 0.0824 0.0824
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.0526 0.0742
Brugia malayi CHE-14 protein 0.0088 0.0862 0.1216
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.1217 0.1217
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0137 0.0334
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0025 0.0108 0.0888
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0273 0.3066 0.4327
Loa Loa (eye worm) hypothetical protein 0.0056 0.0483 0.0682
Brugia malayi Cation transporter family protein 0.002 0.005 0.0071
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.011 0.113 0.113
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.005 0.005
Schistosoma mansoni cpg binding protein 0.006 0.053 0.053
Echinococcus multilocularis ecdysone induced protein 78C 0.0106 0.108 0.108
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.002 0.005 0.0071
Trypanosoma cruzi UDP-glucoronosyl and UDP-glucosyl transferase, putative 0.0054 0.0464 0.1128
Brugia malayi Cytochrome P450 family protein 0.0017 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0056 0.0483 0.0483
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.005 0.0412 0.1002
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0051 0.0123
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.1624 0.2292
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0082 0.0789 0.1114
Onchocerca volvulus Bile acid receptor homolog 0.0262 0.2938 0.7145
Trichomonas vaginalis set domain proteins, putative 0.024 0.267 0.6494
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0129 0.1354 0.3294
Brugia malayi steroid hormone receptor 0.0106 0.108 0.1524
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0072 0.0669 0.1628
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.012 0.124 0.124
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0419 0.0419
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0123 0.1284 0.1812
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0068 0.0624 0.0624
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Schistosoma mansoni RAR-like nuclear receptor 0.0106 0.108 0.108
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.0071
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0129 0.1354 0.3294
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0118 0.0118
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.005 0.005
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0412 0.0412
Entamoeba histolytica rodhanase-like domain containing protein 0.012 0.124 0.3016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0387 0.0387
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0106 0.108 0.1524
Schistosoma mansoni DNA helicase recq1 0.002 0.0053 0.0053
Echinococcus granulosus Desert hedgehog protein 0.0212 0.2341 0.2341
Echinococcus multilocularis nuclear receptor nhr 48 0.005 0.0412 0.0412
Echinococcus granulosus glycine receptor subunit beta 0.002 0.005 0.005
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0273 0.3066 0.4327
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.002 0.005 0.005
Schistosoma mansoni cpg binding protein 0.0063 0.0571 0.0571
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.8087 0.8087
Echinococcus multilocularis nervana 2 0.0068 0.0624 0.0624
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0387 0.0547
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0025 0.0108 0.0108
Echinococcus granulosus Nuclear hormone receptor HR96 0.005 0.0412 0.0412
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0137 0.0334
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.002 0.005 0.005
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0361 0.4112 1
Schistosoma mansoni hypothetical protein 0.0192 0.21 0.21
Loa Loa (eye worm) hypothetical protein 0.0056 0.0483 0.0682
Loa Loa (eye worm) hypothetical protein 0.0058 0.0501 0.0707
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0053 0.0053
Brugia malayi photoreceptor-specific nuclear receptor 0.0106 0.108 0.1524
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0053 0.0053
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0189 0.0189
Echinococcus granulosus carbonic anhydrase 0.0082 0.0789 0.0789
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0051 0.0123
Brugia malayi Pre-SET motif family protein 0.0211 0.2326 0.3282
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0051 0.0123
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.016 0.016
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0731 0.5
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0731 0.1032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0106 0.108 0.1524
Echinococcus multilocularis glycine receptor subunit beta 0.002 0.005 0.005
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.012 0.124 0.124
Schistosoma mansoni hypothetical protein 0.0048 0.0387 0.0387
Schistosoma mansoni single-minded 0.0049 0.0398 0.0398
Schistosoma mansoni nuclear hormone receptor 0.005 0.0412 0.0412
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0326 0.0792
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0255 0.0621
Onchocerca volvulus 0.012 0.124 0.3016
Echinococcus multilocularis cpg binding protein 0.0063 0.0571 0.0571
Loa Loa (eye worm) abnormal epIthelia family member 0.0025 0.0118 0.0166
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.002 0.005 0.005
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.012 0.124 0.3016
Brugia malayi laminin-like protein K08C7.3 precursor 0.0025 0.0118 0.0166
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Brugia malayi Carboxylesterase family protein 0.0025 0.0108 0.0152
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0129 0.1354 0.3294
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0072 0.0669 0.0945
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0082 0.0789 0.1114
Brugia malayi hypothetical protein 0.005 0.0412 0.0581
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0361 0.4112 1
Schistosoma mansoni hypothetical protein 0.0048 0.0387 0.0387
Brugia malayi hypothetical protein 0.0065 0.0586 0.0827
Brugia malayi Nuclear hormone receptor E75 0.005 0.0412 0.0581
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.005 0.0412 0.0412
Echinococcus granulosus Niemann Pick C1 protein 0.0205 0.2254 0.2254
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0255 0.0621
Brugia malayi nuclear receptor RXR 0.005 0.0412 0.0581
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0731 0.1778
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0731 0.1778
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.005 0.0412 0.0412
Brugia malayi ecdysteroid receptor 0.0262 0.2938 0.4146
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0862 0.1216
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0082 0.0789 0.1114
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0051 0.0071
Schistosoma mansoni jun-related protein 0.0067 0.0613 0.0613
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0053 0.0128
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0255 0.0621
Trypanosoma cruzi lanosterol synthase, putative 0.0144 0.1536 0.3735
Loa Loa (eye worm) histone methyltransferase 0.002 0.0049 0.007
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.005 0.0412 0.0581
Schistosoma mansoni nuclear receptor 0.005 0.0412 0.0412
Onchocerca volvulus 0.0025 0.0108 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.0071
Schistosoma mansoni hypothetical protein 0.0085 0.0824 0.0824
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.011 0.113 0.1596
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0252 0.2818 0.3978
Onchocerca volvulus 0.012 0.124 0.3016
Schistosoma mansoni BC026374 protein (S09 family) 0.0025 0.0108 0.0108
Brugia malayi excitatory GABA receptor EXP-1A 0.002 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.0111 0.1142 0.1612
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0255 0.0621
Echinococcus multilocularis geminin 0.0192 0.21 0.21
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0326 0.0459
Onchocerca volvulus 0.0068 0.0624 0.1517
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0106 0.108 0.108
Brugia malayi ecdysone receptor 0.005 0.0412 0.0581
Loa Loa (eye worm) LGC-31 protein 0.002 0.005 0.0071
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.1183 0.2877
Onchocerca volvulus Putative nachr subunit 0.002 0.005 0.0123
Brugia malayi DNA polymerase family B containing protein 0.0129 0.1354 0.1911
Echinococcus multilocularis carboxylesterase 5A 0.0146 0.1549 0.1549
Schistosoma mansoni survival motor neuron protein 0.0049 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0731 0.1778
Entamoeba histolytica recQ family helicase, putative 0.002 0.0053 0.0128
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0082 0.0789 0.1114
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0174 0.1889 0.4595
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Onchocerca volvulus 0.0049 0.0393 0.0956
Onchocerca volvulus 0.0025 0.0108 0.0263
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0106 0.108 0.108
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.1306 0.1306
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Schistosoma mansoni acetylcholinesterase 0.0025 0.0108 0.0108
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.005 0.0412 0.0412
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0049 0.0049
Brugia malayi nuclear receptor RXR 0.0056 0.0483 0.0682
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0137 0.0334
Brugia malayi Carboxylesterase family protein 0.0146 0.1549 0.2186
Loa Loa (eye worm) hypothetical protein 0.0025 0.0118 0.0166
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.002 0.005 0.005
Onchocerca volvulus 0.012 0.124 0.3016
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0361 0.4112 1
Echinococcus multilocularis transcription factor btf3 0.0037 0.0255 0.0255
Brugia malayi Hint module family protein 0.0058 0.0501 0.0707
Onchocerca volvulus 0.024 0.267 0.6494
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0419 0.1018
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0129 0.1354 0.3294
Brugia malayi Carboxylesterase family protein 0.0025 0.0108 0.0152
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.008 0.077 0.1086
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0431 0.0609
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0361 0.4112 0.4112
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0361 0.4112 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0326 0.0792
Onchocerca volvulus 0.0111 0.1142 0.2778
Schistosoma mansoni ap endonuclease 0.0077 0.0731 0.0731
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0255 0.0621
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0387 0.0547
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0326 0.0326
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0106 0.108 0.1524
Brugia malayi Nuclear hormone receptor-like 1 0.0106 0.108 0.1524
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0051 0.0071
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0053 0.0074
Brugia malayi EGF-like domain containing protein 0.0025 0.0118 0.0166
Echinococcus granulosus pikachurin 0.0025 0.0118 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0106 0.108 0.1524
Trypanosoma brucei carbonic anhydrase-like protein 0.0174 0.1889 0.4595
Brugia malayi Hint module family protein 0.0058 0.0501 0.0707
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.005 0.005
Leishmania major geranylgeranyltransferase, putative 0.002 0.0051 0.0123
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0731 0.1778
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0088 0.0862 0.1216
Echinococcus granulosus carbonic anhydrase 0.0082 0.0789 0.0789
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0106 0.108 0.1524
Echinococcus multilocularis nAChR subunit 0.002 0.005 0.005
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0053 0.0053
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0208 0.2292 0.2292
Schistosoma mansoni gliotactin 0.0025 0.0108 0.0108
Entamoeba histolytica rodhanase-like domain containing protein 0.012 0.124 0.3016
Loa Loa (eye worm) hypothetical protein 0.002 0.0053 0.0074
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0393 0.0555
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.1441 0.1441
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0419 0.1018
Echinococcus multilocularis carbonic anhydrase II 0.0174 0.1889 0.1889
Brugia malayi nuclear receptor NHR-88 0.0106 0.108 0.1524
Onchocerca volvulus 0.005 0.0412 0.1002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0056 0.0483 0.0682
Loa Loa (eye worm) steroid hormone receptor 0.0106 0.108 0.1524
Leishmania major farnesyltransferase beta subunit 0.002 0.0051 0.0123
Echinococcus granulosus glycine receptor subunit alpha 1 0.002 0.005 0.005
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0174 0.1889 0.1889
Loa Loa (eye worm) hypothetical protein 0.0146 0.1549 0.2186
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0053 0.0128
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0189 0.0459
Onchocerca volvulus 0.011 0.113 0.2749
Mycobacterium ulcerans carboxylesterase, LipT 0.0025 0.0108 0.0778
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0138 0.1459 0.3549
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.1624 0.2292
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0255 0.0621
Loa Loa (eye worm) hypothetical protein 0.011 0.113 0.1596
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0014 0.002
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0118 0.1217 0.1217
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0106 0.108 0.108
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0419 0.1018
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0051 0.0123
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0021 0.0061 0.0061
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0106 0.108 0.108
Echinococcus multilocularis lamin 0.0111 0.1142 0.1142
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0419 0.1018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0108 0.0108
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0326 0.0792
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0361 0.4112 1
Plasmodium falciparum DNA polymerase zeta catalytic subunit, putative 0.0057 0.05 0.1216
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Schistosoma mansoni hypothetical protein 0.0067 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.002 0.005 0.0071
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0255 0.0621
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0051 0.0123
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0731 1
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.2063 0.5017
Onchocerca volvulus 0.0106 0.108 0.2627
Loa Loa (eye worm) hypothetical protein 0.0057 0.05 0.0705
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.002 0.0051 0.0123
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.002 0.005 0.0071
Echinococcus granulosus lamin dm0 0.0111 0.1142 0.1142
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.002 0.005 0.005
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0138 0.1459 0.3549
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0361 0.4112 1
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0387 0.0547
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0189 0.0189
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.005 0.0071
Giardia lamblia Prenyltransferase 0.002 0.0051 0.0123
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0862 0.0862
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.011 0.113 0.113
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0051 0.0123
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.002 0.005 0.0071
Entamoeba histolytica DNA polymerase zeta catalytic subunit, putative 0.0057 0.05 0.1216
Loa Loa (eye worm) hypothetical protein 0.0058 0.0501 0.0707
Echinococcus granulosus nAChR subunit 0.002 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0048 0.0387 0.0387
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0051 0.0051
Brugia malayi hypothetical protein 0.0017 0.0023 0.0033
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0731 0.1778
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0053 0.0128
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0398 0.0398
Schistosoma mansoni DNA helicase recq5 0.002 0.0053 0.0053
Leishmania major basic transcription factor 3a, putative 0.0037 0.0255 0.0621
Onchocerca volvulus 0.006 0.053 0.129
Loa Loa (eye worm) hypothetical protein 0.0043 0.0326 0.0459
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Loa Loa (eye worm) carbonic anhydrase 3 0.0174 0.1889 0.2666
Loa Loa (eye worm) hypothetical protein 0.0025 0.0108 0.0152
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0731 0.0731
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0053 0.0128
Toxoplasma gondii exonuclease III APE 0.0077 0.0731 0.1778
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0361 0.4112 1
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0025 0.0118 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0255 0.0621
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0068 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.019 0.2074 0.2927
Schistosoma mansoni thyroid hormone receptor 0.0231 0.2572 0.2572
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0051 0.0123
Giardia lamblia Rab geranylgeranyltransferase 0.002 0.0051 0.0123
Brugia malayi nuclear hormone receptor 0.005 0.0412 0.0581
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0169 0.1828 0.1828
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0111 0.1142 0.1612
Echinococcus multilocularis dnaJ subfamily B 0.0855 1 1
Schistosoma mansoni hypothetical protein 0.0055 0.0466 0.0466
Onchocerca volvulus 0.002 0.005 0.0123
Loa Loa (eye worm) hypothetical protein 0.0056 0.0483 0.0682
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0387 0.0387
Schistosoma mansoni ap endonuclease 0.0077 0.0731 0.0731
Brugia malayi nuclear hormone receptor family member odr-7 0.005 0.0412 0.0581
Leishmania major hypothetical protein, conserved 0.0027 0.0137 0.0334
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0387 0.0387
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.053 0.0748
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0247 0.1932
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0106 0.108 0.1524
Schistosoma mansoni carbonic anhydrase 0.0082 0.0789 0.0789
Echinococcus multilocularis acetylcholinesterase 0.0146 0.1549 0.1549
Schistosoma mansoni hypothetical protein 0.0855 1 1
Loa Loa (eye worm) intermediate filament protein 0.0111 0.1142 0.1612
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0326 0.0792
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0082 0.0797 0.0797
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0106 0.108 0.108
Loa Loa (eye worm) hypothetical protein 0.0057 0.05 0.0705
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0129 0.1354 0.3294
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0106 0.108 0.1524
Schistosoma mansoni nAChR subunit 0.002 0.005 0.005
Schistosoma mansoni nuclear hormone receptor 0.0106 0.108 0.108
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.012 0.124 0.175
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0862 0.0862
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0051 0.0051
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0106 0.108 0.2627
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0053 0.0074
Schistosoma mansoni carbonic anhydrase-related 0.0082 0.0789 0.0789
Echinococcus granulosus slit 2 protein 0.0025 0.0118 0.0118
Echinococcus multilocularis bloom syndrome protein 0.002 0.0053 0.0053
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0106 0.108 0.108
Echinococcus granulosus ecdysone induced protein 78C 0.0106 0.108 0.108
Schistosoma mansoni neuroligin 3 (S09 family) 0.0025 0.0108 0.0108
Echinococcus granulosus neuroligin 0.0025 0.0108 0.0108
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0146 0.1549 0.1549
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.005 0.0071
Trypanosoma cruzi lanosterol synthase, putative 0.0144 0.1536 0.3735
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Loa Loa (eye worm) hypothetical protein 0.0052 0.0431 0.0609
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.3066 0.7456
Loa Loa (eye worm) hypothetical protein 0.0072 0.0669 0.0945
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Schistosoma mansoni cpg binding protein 0.0063 0.0571 0.0571
Schistosoma mansoni cell polarity protein 0.0025 0.0118 0.0118
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0129 0.1354 0.1354
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0419 0.1018
Echinococcus granulosus acetylcholinesterase 0.0146 0.1549 0.1549
Plasmodium vivax SET domain protein, putative 0.0031 0.0189 0.0459
Entamoeba histolytica rodhanase-like domain containing protein 0.012 0.124 0.3016
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.3066 0.7456
Echinococcus multilocularis acetylcholinesterase 0.0146 0.1549 0.1549
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0326 0.0792
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0025 0.0108 0.0108
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.002 0.005 0.005
Trichomonas vaginalis cdc25c, putative 0.012 0.124 0.3016
Trichomonas vaginalis glucosylceramidase, putative 0.0273 0.3066 0.7456
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0066 0.0605 0.1471
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0106 0.108 0.1524
Brugia malayi Nuclear hormone receptor E75 0.005 0.0412 0.0581
Brugia malayi nuclear hormone receptor family member nhr-6 0.005 0.0412 0.0581
Brugia malayi nuclear hormone receptor 0.0106 0.108 0.1524
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.011 0.113 0.113
Loa Loa (eye worm) nuclear receptor NHR-67 0.005 0.0412 0.0581
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.012 0.124 0.3016
Brugia malayi tailless protein 0.005 0.0412 0.0581
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Echinococcus granulosus microtubule associated protein 2 0.0694 0.8087 0.8087
Echinococcus granulosus m phase inducer phosphatasecdc25 0.012 0.124 0.124
Brugia malayi hypothetical protein 0.005 0.0412 0.0581
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0082 0.0789 0.1114
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.0526 0.0742
Loa Loa (eye worm) carboxylesterase 0.0025 0.0108 0.0152
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0159 0.1705 0.4146
Echinococcus granulosus GPCR family 2 0.0048 0.0387 0.0387
Echinococcus granulosus FTZ F1 alpha 0.0106 0.108 0.108
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.012 0.124 0.3016
Brugia malayi CXXC zinc finger family protein 0.006 0.053 0.0748
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0051 0.0123
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0014 0.0035
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0051 0.0123
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.1441 0.2033
Brugia malayi Cytochrome P450 family protein 0.0017 0.0014 0.002
Echinococcus granulosus carbonic anhydrase II 0.0174 0.1889 0.1889
Echinococcus multilocularis expressed conserved protein 0.0192 0.2106 0.2106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0106 0.108 0.1524
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0174 0.1889 0.1889
Loa Loa (eye worm) hypothetical protein 0.0027 0.0137 0.0194
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0326 0.0792
Brugia malayi hypothetical protein 0.0056 0.0483 0.0682
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.011 0.113 0.113
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.005 0.005
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0419 0.0419
Brugia malayi hypothetical protein 0.0123 0.1284 0.1812
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0025 0.0108 0.0108
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0455 0.0455
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Schistosoma mansoni hypothetical protein 0.0154 0.1655 0.1655
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0025 0.0108 0.0263
Loa Loa (eye worm) ACC-1 protein 0.002 0.005 0.0071
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0118 0.1217 0.1717
Loa Loa (eye worm) RecQ helicase 0.002 0.0053 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Brugia malayi small heat shock protein 0.061 0.7085 1
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.2326 0.3282
Toxoplasma gondii DNA polymerase 0.0361 0.4112 1
Onchocerca volvulus 0.002 0.005 0.0123
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0118 0.1217 1
Onchocerca volvulus Glucosylceramidase homolog 0.0179 0.1948 0.4738
Onchocerca volvulus 0.002 0.005 0.0123
Onchocerca volvulus Huntingtin homolog 0.0123 0.1284 0.3122
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0419 0.1018
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0361 0.4112 1
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.002 0.005 0.005
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.002 0.005 0.0071
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0053 0.0074
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0361 0.4112 0.4112
Leishmania major lanosterol synthase, putative 0.0125 0.13 0.3162
Echinococcus multilocularis Nuclear hormone receptor HR96 0.005 0.0412 0.0412
Brugia malayi orphan nuclear receptor NR2E1 0.005 0.0412 0.0581
Echinococcus multilocularis musashi 0.0111 0.1142 0.1142
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0129 0.1354 0.1354
Leishmania major carbonic anhydrase-like protein 0.0174 0.1889 0.4595
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0106 0.108 0.1524
Plasmodium vivax DNA polymerase alpha, putative 0.0159 0.1705 0.4146
Onchocerca volvulus 0.005 0.0412 0.1002
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.05 0.1216
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.011 0.113 0.113
Onchocerca volvulus 0.002 0.005 0.0123
Schistosoma mansoni nuclear receptor nhr-48 0.005 0.0412 0.0412
Echinococcus multilocularis slit 2 protein 0.0025 0.0118 0.0118
Echinococcus granulosus geminin 0.0192 0.21 0.21
Loa Loa (eye worm) hypothetical protein 0.0082 0.0789 0.1114
Schistosoma mansoni zinc finger protein 0.005 0.0412 0.0412
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0106 0.108 0.1524
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.002 0.005 0.005
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0326 0.0326
Echinococcus granulosus nervana 2 0.0068 0.0624 0.0624
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0174 0.1889 0.2666
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0053 0.0128
Brugia malayi PAS domain containing protein 0.0049 0.0398 0.0562
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0189 0.0189
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0106 0.108 0.108
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0419 0.1018
Leishmania major DNA polymerase zeta catalytic subunit, putative 0.0057 0.05 0.1216
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0082 0.0789 0.1114
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0731 0.596
Brugia malayi bZIP transcription factor family protein 0.0082 0.0797 0.1124
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0138 0.1459 0.3549
Echinococcus multilocularis para nitrobenzyl esterase 0.0025 0.0108 0.0108
Onchocerca volvulus 0.0025 0.0108 0.0263
Schistosoma mansoni transmemberane protein 0.011 0.113 0.113
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0051 0.0071
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0862 0.0862
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0169 0.1828 0.1828
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0106 0.108 0.108
Mycobacterium tuberculosis Carboxylesterase LipT 0.0025 0.0108 0.0888
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0056 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0056 0.0483 0.0682
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0106 0.108 0.108
Brugia malayi DNA polymerase alpha catalytic subunit 0.0159 0.1705 0.2406
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.019 0.2074 0.5044
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.265 0.265
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.002 0.005 0.0071
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0068 0.0624 0.0624
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0053 0.0128
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.1889 0.2666
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0051 0.0123
Schistosoma mansoni retinoic acid receptor RXR 0.0106 0.108 0.108
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0051 0.0123
Brugia malayi Rhodanese-like domain containing protein 0.012 0.124 0.175
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0326 0.0326
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1948 0.4738
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0387 0.0387
Onchocerca volvulus 0.0065 0.0586 0.1425
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0053 0.0128
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0137 0.0334
Brugia malayi Intermediate filament tail domain containing protein 0.0111 0.1142 0.1612
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.1345 0.1345
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0255 0.036
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0174 0.1889 0.2666
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0118 0.0118
Leishmania major cytochrome p450-like protein 0.0017 0.0014 0.0035
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0082 0.0797 0.0797
Schistosoma mansoni thyroid hormone receptor 0.0231 0.2572 0.2572
Trypanosoma brucei lanosterol synthase 0.0144 0.1536 0.3735
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.002 0.005 0.0071
Onchocerca volvulus Protein ultraspiracle homolog 0.0106 0.108 0.2627
Loa Loa (eye worm) nuclear hormone receptor 0.005 0.0412 0.0581
Schistosoma mansoni lamin 0.0111 0.1142 0.1142
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.011 0.113 0.113
Onchocerca volvulus 0.0036 0.0247 0.06
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0289 0.3257 0.7922
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0051 0.0123
Schistosoma mansoni slit 0.0025 0.0118 0.0118
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0051 0.0123
Plasmodium falciparum carbonic anhydrase 0.0082 0.0789 0.192
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.002 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0106 0.108 0.1524
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0419 0.1018
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0169 0.1828 0.1828
Trypanosoma cruzi DNA polymerase zeta catalytic subunit, putative 0.0057 0.05 0.1216
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.002 0.005 0.0071
Brugia malayi intermediate filament protein 0.0111 0.1142 0.1612
Brugia malayi hypoxia-induced factor 1 0.0152 0.162 0.2286
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.005 0.0412 0.0412
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0361 0.4112 0.4112
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0129 0.1354 0.3294
Brugia malayi Carboxylesterase family protein 0.0025 0.0108 0.0152
Echinococcus multilocularis neuroligin 0.0025 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.005 0.0412 0.0581
Plasmodium falciparum DNA polymerase epsilon catalytic subunit A, putative 0.0072 0.0669 0.1628
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0129 0.1354 0.1354
Echinococcus multilocularis hedgehog 0.0212 0.2341 0.2341
Schistosoma mansoni steroid hormone receptor ad4bp 0.0106 0.108 0.108
Onchocerca volvulus Huntingtin homolog 0.0123 0.1284 0.3122
Loa Loa (eye worm) carboxylesterase 0.0025 0.0108 0.0152
Onchocerca volvulus 0.0111 0.1142 0.2778
Loa Loa (eye worm) hypothetical protein 0.0054 0.0464 0.0654
Loa Loa (eye worm) hypothetical protein 0.061 0.7085 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0106 0.108 0.108
Onchocerca volvulus 0.0025 0.0108 0.0263
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0025 0.0108 0.0888
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0071

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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