Detailed information for compound 82452

Basic information

Technical information
  • TDR Targets ID: 82452
  • Name: 2-amino-5-bromo-6-pyridin-4-yl-1H-pyrimidin-4 -one
  • MW: 267.082 | Formula: C9H7BrN4O
  • H donors: 2 H acceptors: 4 LogP: 1.12 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1nc(O)c(c(n1)c1ccncc1)Br
  • InChi: 1S/C9H7BrN4O/c10-6-7(5-1-3-12-4-2-5)13-9(11)14-8(6)15/h1-4H,(H3,11,13,14,15)
  • InChiKey: QIIMXDWNRPTCFV-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-amino-5-bromo-6-(4-pyridyl)-1H-pyrimidin-4-one
  • 2-azanyl-5-bromo-6-pyridin-4-yl-1H-pyrimidin-4-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0073 0.0434 0.0434
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0715 0.0733
Brugia malayi SET domain containing protein 0.0016 0.0015 0.0025
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Onchocerca volvulus 0.0702 0.5057 1
Leishmania major hypothetical protein, conserved 0.005 0.0266 0.0273
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0071 0.0421 0.0434
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0085 0.0522 0.0522
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0022 0.0055 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.0434 0.0434
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0098 0.0618 0.1388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Trypanosoma brucei unspecified product 0.0026 0.0091 0.0083
Brugia malayi SRC-1 0.0039 0.018 0.0397
Plasmodium falciparum LCCL domain-containing protein 0.0058 0.0325 0.0999
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0039 0.018 0.018
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0098 0.0618 0.1186
Loa Loa (eye worm) hypothetical protein 0.0037 0.0169 0.0382
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Mycobacterium ulcerans glutamate synthase subunit beta 0.0098 0.0618 0.1856
Schistosoma mansoni sulfide quinone reductase 0.0098 0.0618 0.0615
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0266 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0338 0.0629
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.009 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Loa Loa (eye worm) hypothetical protein 0.0198 0.135 0.3047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.042 0.0792
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0045 0.0045
Trichomonas vaginalis Ferredoxin 4 0.0022 0.0055 0.0068
Echinococcus granulosus g protein coupled receptor 0.0073 0.0434 0.0434
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0038 0.018 0.018
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.0601 0.2466
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0021 0.0039
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0021 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0272 0.1894 0.4269
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.0434 0.0434
Schistosoma mansoni hypothetical protein 0.0058 0.0325 0.0321
Schistosoma mansoni glutamate synthase 0.0098 0.0618 0.0615
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0045 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0643 0.1235
Schistosoma mansoni biogenic amine receptor 0.0073 0.0434 0.043
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0206 0.0202
Leishmania major cytochrome p450-like protein 0.0032 0.0129 0.013
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0045 0.0009
Echinococcus granulosus orexin receptor type 2 0.0073 0.0434 0.0434
Echinococcus granulosus dna polymerase eta 0.0038 0.0179 0.0179
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0038 0.0106
Onchocerca volvulus 0.0073 0.0434 0.0784
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium ulcerans oxidoreductase 0.0022 0.0055 0.0055
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.0643 0.0658
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0037 0.0168 0.0163
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0045 0.0101
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0168 0.0163
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0075 0.0107
Plasmodium falciparum ferrodoxin reductase-like protein 0.0098 0.0618 0.1911
Loa Loa (eye worm) hypothetical protein 0.0038 0.0179 0.0404
Trichomonas vaginalis PIKK family atypical protein kinase 0.0076 0.0459 0.0869
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.0129 0.0355
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0098 0.0618 0.1911
Onchocerca volvulus Dual oxidase homolog 0.007 0.0414 0.0745
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Trichomonas vaginalis apoptosis inducing factor, putative 0.0098 0.0618 0.1186
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0022 0.0056 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0286 0.0526
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0316 0.2223 0.6987
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0098 0.0618 0.1186
Echinococcus granulosus tm gpcr rhodopsin 0.0921 0.6664 0.6664
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0016 0.0004
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.0129 0.0291
Mycobacterium ulcerans epimerase 0.002 0.004 0.0006
Onchocerca volvulus 0.0042 0.0206 0.033
Brugia malayi RE15519p 0.0073 0.0434 0.097
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0244 0.0541
Mycobacterium ulcerans NADH dehydrogenase 0.0098 0.0618 0.1856
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0305 0.0689
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0152 0.0152
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0179 0.0395
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0098 0.0618 0.064
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.002 0.0046
Treponema pallidum oxidoreductase 0.0098 0.0618 0.2251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.042 0.0792
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0098 0.0618 0.1882
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0098 0.0618 0.2542
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0206 0.0202
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0715 0.0711
Echinococcus granulosus biogenic amine 5HT receptor 0.0198 0.135 0.135
Schistosoma mansoni opsin-like receptor 0.0073 0.0434 0.043
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0091 0.0083
Loa Loa (eye worm) hypothetical protein 0.0058 0.0325 0.0735
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0349 0.2461 0.2461
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0206 0.0455
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0033 0.0139 0.0133
Schistosoma mansoni microtubule-associated protein tau 0.1375 1 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0073 0.0434 0.043
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0098 0.0618 0.2251
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Giardia lamblia [2Fe-2S] ferredoxin 0.0022 0.0055 0.0066
Plasmodium falciparum ferredoxin, putative 0.0022 0.0055 0.0159
Brugia malayi hypothetical protein 0.0032 0.0135 0.0296
Brugia malayi Cytochrome P450 family protein 0.0032 0.0129 0.0282
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0073 0.0434 0.0434
Trichomonas vaginalis Ferredoxin 3 0.0022 0.0055 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0022 0.0055 0.0124
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0022 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Schistosoma mansoni amine GPCR 0.0073 0.0434 0.043
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.025 0.1735 0.391
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0098 0.0618 0.1911
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0004 0.0004
Brugia malayi Bromodomain containing protein 0.0039 0.0185 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0045 0.0092
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.0129 0.0355
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0075 0.0107
Toxoplasma gondii exonuclease III APE 0.0019 0.0038 0.0106
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.0129 0.0122
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0022 0.0055 0.0055
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0244 0.0244
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.0434 0.043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Brugia malayi sulfakinin receptor protein 0.0073 0.0434 0.097
Chlamydia trachomatis thioredoxin reductase 0.0098 0.0618 0.2199
Schistosoma mansoni hypothetical protein 0.0096 0.0603 0.0599
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0045 0.0101
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0117 0.0118
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0646 0.145
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi nuclear hormone receptor 0.002 0.0045 0.0092
Echinococcus granulosus lamin dm0 0.008 0.0483 0.0483
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0016 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0555 0.106
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0367 0.0819
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.016 0.0156
Echinococcus granulosus glutamate synthase 0.0098 0.0618 0.0618
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0016 0.0036
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.0643 0.1451
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0244 0.0244
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0442 0.099
Brugia malayi Protein kinase domain containing protein 0.0015 0.0006 0.0004
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0035 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0047 0.0244 0.0239
Leishmania major NADH dehydrogenase, putative 0.0098 0.0618 0.064
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.0129 0.0355
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0045 0.0045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.132 0.9597 1
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0117 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0038 0.0028
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0325 0.0325
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.037 0.2616 0.8245
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0098 0.0618 0.0618
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0544 0.1229
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0099 0.0621 0.1401
Echinococcus granulosus thioredoxin glutathione reductase 0.0452 0.3219 0.3219
Schistosoma mansoni hypothetical protein 0.0791 0.5712 0.5711
Echinococcus multilocularis fmrfamide receptor 0.0073 0.0434 0.0434
Plasmodium falciparum thioredoxin reductase 0.0452 0.3219 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0993 0.2233
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0056 0.0126
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.0643 0.0658
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0073 0.0434 0.043
Brugia malayi larval opioid receptor 0.0073 0.0434 0.097
Loa Loa (eye worm) AGC/PKG protein kinase 0.0015 0.0004 0.0009
Onchocerca volvulus 0.0058 0.0325 0.0569
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0098 0.0618 0.1882
Leishmania major C-8 sterol isomerase-like protein 0.0377 0.2667 0.2776
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0258 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.016 0.0276
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0038 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Echinococcus granulosus g protein coupled receptor 0.0073 0.0434 0.0434
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0021 0.001
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.002 0.002
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0199 0.1359 0.4225
Brugia malayi G-protein coupled receptor 0.0073 0.0434 0.097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0098 0.0618 0.064
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0179 0.045
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.037 0.2616 0.8117
Mycobacterium ulcerans oxygenase 0.0022 0.0055 0.0055
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0098 0.0618 0.1911
Onchocerca volvulus 0.0073 0.0434 0.0784
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.0129 0.0355
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0206 0.0202
Echinococcus multilocularis 0.0032 0.0129 0.0129
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.009 0.0555 0.0566
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0045 0.0092
Schistosoma mansoni lamin 0.008 0.0483 0.0479
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0025 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.0618 0.0633
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0038 0.0086
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0073 0.0434 0.0434
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0045 0.0045
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0555 0.1252
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0971 0.3614
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0075 0.0107
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0098 0.0618 0.1882
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0075 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Echinococcus granulosus tyrosine protein kinase Src64B 0.0039 0.018 0.018
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0056 0.0056
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Trypanosoma brucei electron transfer protein, putative 0.0022 0.0055 0.0045
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0167 0.0167
Schistosoma mansoni amine GPCR 0.0073 0.0434 0.043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.132 0.9597 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0055 0.0045
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.037 0.2616 0.8117
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0118 0.0319
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Onchocerca volvulus 0.0098 0.0618 0.1153
Treponema pallidum hypothetical protein 0.0109 0.0699 0.2562
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.016 0.059
Loa Loa (eye worm) hypothetical protein 0.0104 0.0659 0.1487
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0128 0.0839 0.256
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.0129 0.0291
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0098 0.0618 0.1882
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Loa Loa (eye worm) neuropeptide F receptor 0.0073 0.0434 0.0979
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0073 0.0434 0.0784
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0098 0.0618 0.1882
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0286 0.0526
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0367 0.037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Leishmania major ferric reductase, putative 0.0033 0.0139 0.0141
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0993 0.2233
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium ulcerans dehydrogenase 0.0098 0.0618 0.1856
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.009 0.0555 0.1244
Schistosoma mansoni biogenic amine receptor 0.0073 0.0434 0.043
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.0129 0.0291
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0442 0.1332
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0005 0.0001
Mycobacterium ulcerans hypothetical protein 0.0098 0.0618 0.1856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.042 0.0792
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.037 0.2616 1
Trypanosoma brucei unspecified product 0.0026 0.0091 0.0083
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0056 0.0069
Brugia malayi nuclear receptor NHR-88 0.002 0.0045 0.0092
Schistosoma mansoni neuropeptide F-like receptor 0.0073 0.0434 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0457
Brugia malayi ecdysteroid receptor 0.002 0.0045 0.0092
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0168 0.038
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0118 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0035 0.0028
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0022 0.0056 0.0056
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0085 0.052 0.052
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0098 0.0618 0.2245
Giardia lamblia Thioredoxin reductase 0.0098 0.0618 0.2251
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.037 0.2616 0.8245
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0098 0.0618 0.1882
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0056 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0045 0.0101
Brugia malayi GnHR receptor homolog 0.0073 0.0434 0.097
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0971 0.7034 0.7328
Echinococcus multilocularis tyrosine protein kinase Srms 0.0035 0.0152 0.0152
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0971 0.7034 0.7325
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0179 0.0175
Brugia malayi Melatonin receptor type 1A 0.0073 0.0434 0.097
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0227 0.1562 0.4875
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0531 0.3802 0.858
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0098 0.0618 0.1911
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0118 0.0353
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0045 0.0092
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0179 0.0174
Onchocerca volvulus 0.0022 0.0055 0.003
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0045 0.0009
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.0129 0.0355
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0021 0.0039
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0206 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0117 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0715 0.1377
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1111 0.8061 0.8399
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0075 0.0107
Echinococcus granulosus alpha 1A adrenergic receptor 0.0073 0.0434 0.0434
Schistosoma mansoni survival motor neuron protein 0.0096 0.0603 0.0599
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0179 0.0179
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0073 0.0434 0.043
Loa Loa (eye worm) intermediate filament protein 0.008 0.0483 0.109
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0247 0.1716 0.3867
Loa Loa (eye worm) G-protein coupled receptor 0.0073 0.0434 0.0979
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0206 0.0202
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0098 0.0618 0.0633
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0211 0.0476
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0098 0.0618 0.0633
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0118 0.0244
Echinococcus multilocularis lamin 0.008 0.0483 0.0483
Brugia malayi Dopamine receptor protein 1 0.0073 0.0434 0.097
Schistosoma mansoni hypothetical protein 0.0102 0.0646 0.0642
Loa Loa (eye worm) neuropeptide F receptor 0.0073 0.0434 0.0979
Brugia malayi G protein-coupled receptor 0.0073 0.0434 0.097
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.009 0.0555 0.0574
Schistosoma mansoni growth hormone secretagogue receptor 0.0073 0.0434 0.043
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0098 0.0618 0.1186
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.016 0.0472
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0038 0.018 0.0406
Brugia malayi hypothetical protein 0.005 0.0266 0.0591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0458
Schistosoma mansoni bromodomain containing protein 0.0068 0.0396 0.0392
Leishmania major ferredoxin, 2fe-2s-like protein 0.0022 0.0055 0.0053
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0042 0.0206 0.0587
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0021 0.0021
Trypanosoma cruzi NADH dehydrogenase, putative 0.0098 0.0618 0.0633
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.132 0.9597 1
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0045 0.0101
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.009 0.0555 0.227
Echinococcus granulosus serotonin transporter 0.0247 0.1716 0.1716
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0056 0.0052
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.0129 0.0291
Mycobacterium tuberculosis Possible oxygenase 0.0022 0.0055 0.0124
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0179 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0021 0.0021
Trypanosoma cruzi target of rapamycin kinase 3 0.0071 0.0421 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0643 0.0639
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0022 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0266 0.0265
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0227 0.1562 0.4828
Echinococcus multilocularis neuropeptide Y receptor 0.0073 0.0434 0.0434
Treponema pallidum NADH oxidase 0.037 0.2616 1
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0085 0.052 0.0516
Trypanosoma cruzi trypanothione reductase, putative 0.0452 0.3219 0.3346
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase Blk 0.0035 0.0152 0.0152
Echinococcus multilocularis neuropeptide s receptor 0.0518 0.3708 0.3708
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0098 0.0618 0.2542
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0038 0.0034
Onchocerca volvulus 0.0073 0.0434 0.0784
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0098 0.0618 0.1396
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.037 0.2616 0.2616
Schistosoma mansoni cpg binding protein 0.0056 0.0305 0.0301
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0073 0.0434 0.043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1111 0.8061 0.8398
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Onchocerca volvulus 0.0247 0.1716 0.3341
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.029 0.0534
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.016 0.016
Brugia malayi Dopamine receptor 0.0073 0.0434 0.097
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0206 0.0206
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0671 0.483 0.9551
Giardia lamblia DNA repair protein RAD52 0.0337 0.2371 0.9051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0045 0.0101
Echinococcus multilocularis thioredoxin glutathione reductase 0.0452 0.3219 0.3219
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0098 0.0618 0.1388
Loa Loa (eye worm) hypothetical protein 0.0497 0.3549 0.801
Brugia malayi 6-phosphofructokinase 0.0111 0.0716 0.1607
Mycobacterium tuberculosis Probable reductase 0.0098 0.0618 0.1882
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0386 0.0725
Mycobacterium ulcerans hypothetical protein 0.0109 0.0699 0.2112
Loa Loa (eye worm) hypothetical protein 0.0247 0.1716 0.3873
Brugia malayi hypothetical protein 0.0471 0.3359 0.7579
Loa Loa (eye worm) hypothetical protein 0.0247 0.1716 0.3873
Loa Loa (eye worm) hypothetical protein 0.0037 0.0171 0.0386
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0118 0.0244
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.002 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.3359 0.3359
Loa Loa (eye worm) solute carrier family 6 member 4 0.0247 0.1716 0.3873
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0118 0.0353
Onchocerca volvulus 0.0042 0.0206 0.033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0455
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.0434 0.043
Echinococcus granulosus neuropeptide receptor 0.0073 0.0434 0.0434
Leishmania major dihydrolipoamide dehydrogenase, putative 0.037 0.2616 0.2722
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.009 0.0555 0.0574
Loa Loa (eye worm) hypothetical protein 0.0017 0.0021 0.0048
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0098 0.0618 0.2245
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0106 0.0101
Leishmania major cytochrome p450-like protein 0.0032 0.0129 0.013
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.0129 0.0291
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0098 0.0618 0.1882
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0098 0.0618 0.1856
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.018 0.018
Echinococcus multilocularis geminin 0.0338 0.2378 0.2378
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0047 0.0244 0.055
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0098 0.0618 0.1856
Echinococcus multilocularis neuropeptide receptor 0.0073 0.0434 0.0434
Echinococcus multilocularis neuropeptides capa receptor 0.0073 0.0434 0.0434
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0022 0.0055 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0258 0.0581
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.3359 0.3359
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0118 0.0192
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.003 0.0067
Echinococcus multilocularis serotonin transporter 0.0247 0.1716 0.1716
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0073 0.0434 0.0434
Treponema pallidum sodium- and chloride- dependent transporter 0.0247 0.1716 0.651
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0081 0.0489 0.1096
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.009 0.0555 0.1713
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0464
Echinococcus multilocularis ferredoxin adrenodoxin 0.0022 0.0055 0.0055
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.009 0.0555 0.0551
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0045 0.0041
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0118 0.0411
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0037 0.0168 0.0371
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.0129 0.0345
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0098 0.0618 0.1186
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0045 0.0092
Echinococcus granulosus dna polymerase kappa 0.0038 0.0179 0.0179
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0081 0.0489 0.0489
Trypanosoma brucei cytochrome P450, putative 0.0049 0.0258 0.0256
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0085 0.052 0.052
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0445 0.3164 1
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0168 0.0292
Echinococcus granulosus tyrosine protein kinase Lyn 0.0039 0.0187 0.0187
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0098 0.0618 0.0633
Onchocerca volvulus 0.0042 0.0206 0.033
Echinococcus multilocularis neuropeptides capa receptor 0.0073 0.0434 0.0434
Schistosoma mansoni ap endonuclease 0.0019 0.0038 0.0034
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0247 0.1716 0.1713
Plasmodium falciparum transporter, putative 0.0042 0.0206 0.0627
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0037 0.0168 0.0168
Schistosoma mansoni neuropeptide f receptor 76f 0.0073 0.0434 0.043
Brugia malayi Bromodomain containing protein 0.008 0.0484 0.1085
Schistosoma mansoni histamine h1 receptor 0.0073 0.0434 0.043
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.037 0.2616 0.8117
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0098 0.0618 0.1882
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0056 0.0056
Echinococcus multilocularis allatostatin A receptor 0.0073 0.0434 0.0434
Onchocerca volvulus 0.0073 0.0434 0.0784
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0073 0.0434 0.097
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0452 0.3219 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0098 0.0618 0.1911
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0037 0.0168 0.0511
Loa Loa (eye worm) hypothetical protein 0.005 0.0266 0.06
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0045 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0055 0.0045
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0349 0.2461 0.2461
Schistosoma mansoni loxhd1 0.0058 0.0325 0.0321
Trichomonas vaginalis Ferredoxin 1 0.0022 0.0055 0.0068
Loa Loa (eye worm) TK protein kinase 0.0035 0.0152 0.0344
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.1735 0.3404
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0039 0.0185 0.0419
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0442 0.1363
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0369 0.0369
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0118 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0117 0.0191
Echinococcus multilocularis neuropeptide FF receptor 2 0.0073 0.0434 0.0434
Echinococcus granulosus Adrenodoxin mitochondrial 0.0022 0.0055 0.0055
Loa Loa (eye worm) SRC-1 0.0039 0.018 0.0406
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0045 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Echinococcus granulosus lamin 0.008 0.0483 0.0483
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Schistosoma mansoni hypothetical protein 0.0023 0.0062 0.0058
Onchocerca volvulus 0.0073 0.0434 0.0784
Schistosoma mansoni thyroid hormone receptor 0.002 0.0045 0.0041
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0621 0.0617
Echinococcus granulosus neuropeptide FF receptor 2 0.0073 0.0434 0.0434
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0073 0.0434 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.1735 0.3404
Echinococcus multilocularis cpg binding protein 0.0061 0.0343 0.0343
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0073 0.0434 0.0434
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0045 0.0041
Brugia malayi glutathione reductase 0.0452 0.3219 0.7262
Brugia malayi CHD4 protein 0.0017 0.002 0.0036
Loa Loa (eye worm) doublecortin family protein 0.0058 0.0325 0.0735
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.0129 0.0291
Echinococcus multilocularis fmrfamide receptor 0.0073 0.0434 0.0434
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.0683 0.0679
Onchocerca volvulus 0.0056 0.0305 0.0528
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0206 0.0206
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0071 0.0421 0.0421
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0244 0.0244
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0033 0.0139 0.0133
Schistosoma mansoni zinc finger protein 0.0016 0.0012 0.0008
Schistosoma mansoni hypothetical protein 0.0073 0.0434 0.043
Plasmodium falciparum thioredoxin reductase 0.037 0.2616 0.8124
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0367 0.0367
Schistosoma mansoni hypothetical protein 0.0032 0.0129 0.0125
Plasmodium vivax glutathione reductase, putative 0.0452 0.3219 1
Echinococcus multilocularis expressed conserved protein 0.0015 0.0004 0.0004
Onchocerca volvulus 0.002 0.0045 0.0009
Trichomonas vaginalis Ferredoxin 6 0.0022 0.0055 0.0068
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0073 0.0434 0.0434
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Loa Loa (eye worm) hypothetical protein 0.0042 0.0203 0.0459
Loa Loa (eye worm) cytochrome P450 0.0032 0.0129 0.0292
Schistosoma mansoni tyrosine kinase 0.0039 0.018 0.0176
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0603 0.1353
Entamoeba histolytica hypothetical protein 0.0096 0.0601 0.2466
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0098 0.0618 0.1856
Treponema pallidum hypothetical protein 0.009 0.0557 0.2013
Trypanosoma cruzi trypanothione reductase, putative 0.037 0.2616 0.2716
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0266 0.0814
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0993 0.224
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0045 0.0041
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0025 0.0021
Echinococcus multilocularis conserved hypothetical protein 0.0706 0.5089 0.5089
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0715 0.0733
Chlamydia trachomatis endonuclease IV 0.0074 0.0442 0.1511
Echinococcus granulosus tyrosine protein kinase HCK 0.0031 0.0124 0.0124
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0022 0.0055 0.0159
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0098 0.0618 0.0633
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0045 0.0045
Brugia malayi Doublecortin family protein 0.0058 0.0325 0.0726
Plasmodium falciparum glutathione reductase 0.0452 0.3219 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0058 0.0325 0.0325
Loa Loa (eye worm) apoptosis regulator protein 0.0085 0.052 0.1173
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.016 0.016
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0712 0.2202
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0016 0.0036
Echinococcus granulosus tachykinin peptides receptor 99D 0.0073 0.0434 0.0434
Trichomonas vaginalis aldehyde oxidase, putative 0.0671 0.483 0.9551
Echinococcus multilocularis GPCR, family 2 0.0047 0.0244 0.0244
Giardia lamblia NADH oxidase lateral transfer candidate 0.037 0.2616 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.042 0.0792
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0179 0.051
Loa Loa (eye worm) hypothetical protein 0.0072 0.0429 0.0968
Schistosoma mansoni polycystin 1-related 0.0058 0.0325 0.0321
Echinococcus granulosus neuropeptide s receptor 0.0518 0.3708 0.3708
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0715 0.2164
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0179 0.0313
Echinococcus granulosus dnaJ subfamily B 0.0791 0.5712 0.5712
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.0129 0.0291
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0367 0.0363
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.037 0.2616 0.2716
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0098 0.0618 0.1882
Schistosoma mansoni sulfide quinone reductase 0.0098 0.0618 0.0615
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0073 0.0434 0.043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0056 0.0126
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.0129 0.0291
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.018 0.018
Echinococcus multilocularis g-protein coupled receptor 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0017 0.0025 0.0057
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0022 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.0129 0.0355
Schistosoma mansoni opsin-like receptor 0.0073 0.0434 0.043
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0098 0.0618 0.1388
Mycobacterium ulcerans monoxygenase 0.0098 0.0618 0.1856
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0098 0.0618 0.0618
Leishmania major hypothetical protein, conserved 0.0022 0.0055 0.0053
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0055 0.0053
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0258 0.0581
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0047 0.0047
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.037 0.2616 0.8124
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0056 0.0052
Echinococcus granulosus nuclear factor of activated T cells 5 0.0071 0.0421 0.0421
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0179 0.0179
Schistosoma mansoni lipoxygenase 0.0244 0.1689 0.1686
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0098 0.0618 0.1882
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0179 0.0174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0555 0.0551
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0206 0.0206
Leishmania major ferredoxin 2fe-2s-like protein 0.0022 0.0055 0.0053
Entamoeba histolytica protein kinase, putative 0.0031 0.0124 0.0438
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0369 0.0369
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.0129 0.0389
Echinococcus multilocularis glutamate synthase 0.0098 0.0618 0.0618
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0017 0.0021 0.0021
Trichomonas vaginalis glutamate synthase, putative 0.0098 0.0618 0.1186
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0376 0.2659 0.2656
Echinococcus multilocularis neuropeptide receptor 0.0073 0.0434 0.0434
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0038 0.0028
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0098 0.0618 0.0618
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0022 0.0056 0.0056
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0206 0.0206
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0377 0.2667 0.277
Onchocerca volvulus 0.0073 0.0434 0.0784
Brugia malayi Intermediate filament tail domain containing protein 0.008 0.0483 0.1082
Leishmania major trypanothione reductase 0.0452 0.3219 0.3351
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0091 0.0083
Loa Loa (eye worm) CYP4Cod1 0.0049 0.0258 0.0581
Onchocerca volvulus 0.0073 0.0434 0.0784
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0179 0.0395
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0117 0.011
Onchocerca volvulus 0.0058 0.0325 0.0569
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0118 0.0319
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0056 0.0056
Brugia malayi neuropeptide F receptor 0.0073 0.0434 0.097
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.018 0.018
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0018 0.0031 0.007
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0098 0.0618 0.1186
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.006 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0921 0.6664 0.6664
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0045 0.0092
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0145 0.0145
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0098 0.0618 0.1186
Schistosoma mansoni apoptosis regulator bax 0.0085 0.052 0.0516
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0045 0.0092
Trichomonas vaginalis mercuric reductase, putative 0.037 0.2616 0.5153
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0062 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Plasmodium vivax ferredoxin, putative 0.0022 0.0055 0.0124
Brugia malayi follicle stimulating hormone receptor 0.0531 0.3802 0.8579
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0266 0.0265
Echinococcus granulosus neuropeptides capa receptor 0.0073 0.0434 0.0434
Schistosoma mansoni neuropeptide receptor 0.0073 0.0434 0.043
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.0129 0.0291
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0073 0.0434 0.0979
Echinococcus granulosus tyrosine protein kinase Blk 0.0035 0.0152 0.0152
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0028 0.0106 0.0106
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0045 0.0045
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0098 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0471 0.3359 0.7581
Schistosoma mansoni hypothetical protein 0.0073 0.0434 0.043
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0715 0.1377
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.0643 0.1987
Brugia malayi neuropeptide F receptor 0.0073 0.0434 0.097
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0179 0.0404
Echinococcus multilocularis neuropeptide Y receptor 0.0073 0.0434 0.0434
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0179 0.0174
Onchocerca volvulus 0.0073 0.0434 0.0784
Schistosoma mansoni hypothetical protein 0.0073 0.0434 0.043
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0073 0.0434 0.0979
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0073 0.0434 0.043
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi MAP kinase sur-1 0.0101 0.0643 0.1443
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0377 0.2667 0.6016
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0056 0.0056
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0643 0.1235
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0033 0.0139 0.0133
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0316 0.2223 0.689
Leishmania major DNA polymerase eta, putative 0.0038 0.0179 0.0182
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0039 0.018 0.018
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.009 0.009
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0025 0.0025
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0038 0.0028
Schistosoma mansoni neuropeptide receptor 0.0073 0.0434 0.043
Echinococcus multilocularis dnaJ subfamily B 0.0791 0.5712 0.5712
Loa Loa (eye worm) hypothetical protein 0.008 0.0483 0.109
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.018 0.018
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.016 0.016
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0025 0.0025
Toxoplasma gondii ferredoxin, putative 0.0022 0.0055 0.0159
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0715 0.2951
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0092 0.0573 0.0573
Toxoplasma gondii hypothetical protein 0.0042 0.0206 0.0627
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.0129 0.0355
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0715 0.1613
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0017 0.0021 0.0021
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0045 0.0041
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0073 0.0434 0.0979
Toxoplasma gondii selenide, water dikinase 0.0098 0.0618 0.1911
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.0129 0.0355
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0266 0.0814
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0715 0.1613
Onchocerca volvulus 0.0104 0.0659 0.1233
Onchocerca volvulus 0.008 0.0483 0.0883
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.037 0.2616 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0107 0.0683 0.0683
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.0129 0.0129
Echinococcus granulosus tyrosine kinase 0.0035 0.0152 0.0152
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0455
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0045 0.0045
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0045 0.0045
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0098 0.0618 0.2245
Mycobacterium ulcerans electron transfer protein 0.0022 0.0055 0.0055
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0098 0.0618 0.1856
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0073 0.0434 0.043
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0016 0.0036
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0206 0.0206
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0971 0.7034 0.7325
Loa Loa (eye worm) hypothetical protein 0.0198 0.135 0.3047
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0643 0.1235
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.0129 0.0291
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.1735 0.3404
Leishmania major DNA polymerase kappa, putative 0.0038 0.0179 0.0182
Giardia lamblia GTOR 0.009 0.0555 0.2004
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0325 0.0325
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0118 0.0353
Brugia malayi hypothetical protein 0.0058 0.0325 0.0726
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0098 0.0618 0.0618
Trichomonas vaginalis Ferredoxin 2 0.0022 0.0055 0.0068
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Mycobacterium leprae putative cytochrome p450 0.0032 0.0129 0.0345
Echinococcus granulosus biogenic amine 5HT receptor 0.0438 0.3113 0.3113
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0045 0.0041
Loa Loa (eye worm) hypothetical protein 0.0497 0.3549 0.801
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0073 0.0434 0.043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Echinococcus granulosus neuropeptide Y receptor 0.0073 0.0434 0.0434
Onchocerca volvulus 0.0073 0.0434 0.0784
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Brugia malayi hypothetical protein 0.0104 0.066 0.1481
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.009 0.009
Echinococcus granulosus Polycystic kidney disease protein 0.0058 0.0325 0.0325
Entamoeba histolytica disulphide oxidoreductase, putative 0.0098 0.0618 0.2542
Echinococcus granulosus cpg binding protein 0.0061 0.0343 0.0343
Schistosoma mansoni cytochrome P450 0.0032 0.0129 0.0125
Loa Loa (eye worm) hypothetical protein 0.0193 0.1313 0.2963
Echinococcus multilocularis zinc finger protein 0.0023 0.0067 0.0067
Schistosoma mansoni lipoxygenase 0.0349 0.2461 0.2458
Mycobacterium ulcerans hypothetical protein 0.002 0.004 0.0006
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0431 0.0813
Plasmodium vivax thioredoxin reductase, putative 0.0452 0.3219 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0367 0.037
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0272 0.1894 0.4269
Plasmodium vivax SET domain protein, putative 0.009 0.0555 0.1683
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.0129 0.0291
Echinococcus granulosus fmrfamide receptor 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trichomonas vaginalis set domain proteins, putative 0.0702 0.5056 1
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0098 0.0618 0.0633
Brugia malayi Tachykinin-like peptides receptor 99D 0.0073 0.0434 0.097
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0715 0.0741
Schistosoma mansoni nuclear hormone receptor 0.002 0.0045 0.0041
Schistosoma mansoni disulfide oxidoreductase 0.0098 0.0618 0.0615
Echinococcus multilocularis g protein coupled receptor 0.0073 0.0434 0.0434
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0022 0.0022
Brugia malayi Serotonin receptor 0.0544 0.3895 0.879
Echinococcus granulosus serotonin receptor 0.0073 0.0434 0.0434
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0081 0.0489 0.0489
Schistosoma mansoni hypothetical protein 0.0085 0.052 0.0516
Toxoplasma gondii hypothetical protein 0.0042 0.0206 0.0627
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.0643 0.0666
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0169 0.0169
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0045 0.0041
Schistosoma mansoni hypothetical protein 0.0338 0.2378 0.2374
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0038 0.0071
Schistosoma mansoni hypothetical protein 0.0021 0.0052 0.0048
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0045 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Loa Loa (eye worm) hypothetical protein 0.0194 0.1326 0.2994
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0179 0.0672
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0442 0.1332
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0098 0.0618 0.1186
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0206 0.0593
Schistosoma mansoni zinc finger protein 0.0023 0.0067 0.0063
Brugia malayi PHD-finger family protein 0.0029 0.0108 0.0233
Giardia lamblia DINP protein human, muc B family 0.0038 0.0179 0.0546
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0038 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.0618 0.0633
Toxoplasma gondii endonuclease IV APN 0.0074 0.0442 0.1363
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.008 0.0483 0.109
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0045 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0555 0.106
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0167 0.0167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.2096 0.8829
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Loa Loa (eye worm) hypothetical protein 0.0037 0.0169 0.0382
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0367 0.0367
Trypanosoma brucei C-8 sterol isomerase, putative 0.0377 0.2667 0.277
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.016 0.0156
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0118 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0016 0.0013 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0117 0.0191
Brugia malayi hypothetical protein 0.0042 0.0206 0.0455
Echinococcus multilocularis g protein coupled receptor 0.0073 0.0434 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0117 0.0191
Schistosoma mansoni cpg binding protein 0.0061 0.0343 0.0339
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.016 0.016
Onchocerca volvulus 0.0073 0.0434 0.0784
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.1168 0.2277
Brugia malayi Cytochrome P450 family protein 0.0049 0.0258 0.0572
Trichomonas vaginalis glutathione reductase, putative 0.037 0.2616 0.5153
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0035 0.0097
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0098 0.0618 0.2251
Plasmodium vivax ferrodoxin reductase, putative 0.0098 0.0618 0.1882
Brugia malayi intermediate filament protein 0.008 0.0483 0.1082
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.037 0.2616 0.2716
Echinococcus granulosus G protein coupled receptor 139 0.0073 0.0434 0.0434
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1111 0.8061 0.8398
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0016 0.0011
Mycobacterium ulcerans endonuclease IV 0.0074 0.0442 0.1292
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.009 0.0555 0.0555
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0045 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.029 0.0534
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0045 0.0045
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0101 0.0641 0.0637
Plasmodium vivax amine transporter, putative 0.0042 0.0206 0.0593
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0627
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0092 0.0573 0.0569
Echinococcus granulosus ferredoxin 0.0022 0.0055 0.0055
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0022 0.0056 0.0056
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0062 0.0062
Schistosoma mansoni myosin xvIII 0.0073 0.0434 0.043
Brugia malayi G protein-coupled receptor F59B2.13 0.0073 0.0434 0.097
Brugia malayi Pre-SET motif family protein 0.0617 0.4431 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0098 0.0618 0.0633
Onchocerca volvulus 0.0101 0.0641 0.1197
Schistosoma mansoni biogenic amine receptor 0.0073 0.0434 0.043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0075 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.0129 0.0355
Echinococcus multilocularis neuropeptide receptor A26 0.0518 0.3708 0.3708
Schistosoma mansoni hypothetical protein 0.0085 0.052 0.0516
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0021 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0021 0.001
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0085 0.052 0.052
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0039 0.018 0.018
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0045 0.0092
Loa Loa (eye worm) serotonin transporter b 0.0247 0.1716 0.3873
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0038 0.0077
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0056 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.042 0.0792
Schistosoma mansoni adrenodoxin 0.0022 0.0055 0.0051
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.0129 0.0291
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0098 0.0618 0.1186
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.0129 0.0355
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0266 0.0781
Onchocerca volvulus 0.0073 0.0434 0.0784
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0367 0.0827
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.029 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0045 0.0092
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.2096 0.8829
Echinococcus granulosus peptide allatostatin:somatostatin 0.0073 0.0434 0.0434
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.0129 0.0355
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0045 0.0092
Schistosoma mansoni amine GPCR 0.0073 0.0434 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0032 0.0022
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0206 0.0202
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0179 0.0182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0458
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.0643 0.2346
Mycobacterium tuberculosis Probable oxidoreductase 0.0022 0.0055 0.0124
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0179 0.0179
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0206 0.0206
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.018 0.018
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0085 0.052 0.052
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.0643 0.0643
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0038 0.018 0.018
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0971 0.2982
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0098 0.0618 0.1911
Echinococcus granulosus hypothetical protein 0.0779 0.5626 0.5626
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0118 0.0192
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0118 0.0192
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0117 0.0265
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0098 0.0618 0.1186
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0971 0.7034 0.7325
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0022 0.0056 0.0056
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0081 0.0489 0.1104
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0118 0.0192
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.0434 0.0434
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0039 0.018 0.018
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0118 0.0192
Onchocerca volvulus 0.0104 0.0659 0.1233
Brugia malayi hypothetical protein 0.0058 0.0325 0.0726
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.1103 0.2118
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0715 0.0715
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0022 0.0055 0.003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0129 0.0122
Trichomonas vaginalis glutamate synthase, putative 0.0098 0.0618 0.1186
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0045 0.0092
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0715 0.0711
Echinococcus granulosus GPCR family 2 0.0047 0.0244 0.0244
Echinococcus granulosus zinc finger protein 0.0023 0.0067 0.0067
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0098 0.0618 0.2251
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0117 0.011
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0098 0.0618 0.1856
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0627
Loa Loa (eye worm) hypothetical protein 0.0074 0.0442 0.0998
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.018 0.018
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0715 0.2951
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0039 0.018 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.1735 0.3404
Trichomonas vaginalis PIKK family atypical protein kinase 0.0058 0.0324 0.0601
Brugia malayi cytochrome P450 0.0032 0.0129 0.0282
Loa Loa (eye worm) G-protein coupled receptor 0.0073 0.0434 0.0979
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0227 0.1562 0.4875
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0073 0.0434 0.0979
Loa Loa (eye worm) hypothetical protein 0.0102 0.0646 0.1458
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0037 0.0168 0.0371
Brugia malayi Dopamine receptor protein 2 0.0073 0.0434 0.097
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.037 0.2616 0.2616
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0206 0.0627
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Schistosoma mansoni adrenodoxin 0.0022 0.0055 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0075 0.0107
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0028 0.0106 0.0229
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Echinococcus multilocularis dna polymerase eta 0.0038 0.0179 0.0179
Schistosoma mansoni amine GPCR 0.0073 0.0434 0.043
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.0129 0.0291
Echinococcus multilocularis tumor protein p63 0.0673 0.4844 0.4844
Schistosoma mansoni opsin-like receptor 0.0073 0.0434 0.043
Echinococcus multilocularis orexin receptor type 2 0.0073 0.0434 0.0434
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0128 0.0839 0.2569
Schistosoma mansoni neuropeptide receptor 0.0073 0.0434 0.043
Schistosoma mansoni sodium/chloride dependent transporter 0.0247 0.1716 0.1713
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0016 0.0004
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0627
Leishmania major dihydrolipoamide dehydrogenase, putative 0.132 0.9597 1
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0098 0.0618 0.2542
Entamoeba histolytica thioredoxin reductase, putative 0.0098 0.0618 0.2542
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0715 0.1377
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.016 0.0276
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.0643 0.0643
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0098 0.0618 0.2245
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0715 0.2618
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0117 0.011
Schistosoma mansoni voltage-gated potassium channel 0.0087 0.0539 0.0535
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0458
Schistosoma mansoni rab6-interacting 0.0058 0.0325 0.0321
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0098 0.0618 0.0618
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0455
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.0129 0.0355
Echinococcus granulosus histone lysine methyltransferase setb 0.0107 0.0683 0.0683
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0021 0.0017
Echinococcus multilocularis G protein coupled receptor 139 0.0073 0.0434 0.0434
Mycobacterium ulcerans oxidoreductase 0.0022 0.0055 0.0055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.037 0.2616 0.8117
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0022 0.0055 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0045 0.0101
Brugia malayi glutamate synthase 0.0098 0.0618 0.1388
Onchocerca volvulus 0.0073 0.0434 0.0784
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0037 0.0168 0.0164
Loa Loa (eye worm) hypothetical protein 0.0149 0.0993 0.224
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0715 0.2951
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0169 0.0169
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.009 0.0086
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Schistosoma mansoni voltage-gated potassium channel 0.0087 0.0539 0.0535
Plasmodium falciparum glutathione reductase 0.037 0.2616 0.8124
Echinococcus granulosus 7TM GPCR rhodopsin 0.0073 0.0434 0.0434
Brugia malayi Cytochrome P450 family protein 0.0049 0.0258 0.0572
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0715 0.2624
Giardia lamblia Glutamate synthase 0.0098 0.0618 0.2251
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.2096 0.7983
Mycobacterium ulcerans electron transfer protein FdxB 0.0022 0.0055 0.0055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.016 0.0154
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0056 0.0052
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.0129 0.0291
Onchocerca volvulus 0.0073 0.0434 0.0784
Echinococcus granulosus tumor protein p63 0.0673 0.4844 0.4844
Onchocerca volvulus 0.0073 0.0434 0.0784
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0128 0.0839 0.256
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0004 0.0004
Toxoplasma gondii target of rapamycin (TOR), putative 0.0067 0.0386 0.1188
Echinococcus granulosus allatostatin A receptor 0.0073 0.0434 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Schistosoma mansoni glutamate synthase 0.0098 0.0618 0.0615
Echinococcus multilocularis tyrosine protein kinase HCK 0.0031 0.0124 0.0124
Echinococcus multilocularis RUN 0.0058 0.0325 0.0325
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0037 0.0168 0.0163
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0179 0.0313
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0376 0.2659 0.5997
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.0129 0.0291
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.0129 0.0355
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0206 0.0202
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0052 0.0117
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.0129 0.0122
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0045 0.0009
Echinococcus granulosus FTZ F1 alpha 0.002 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Loa Loa (eye worm) hypothetical protein 0.0036 0.016 0.0361
Onchocerca volvulus 0.0073 0.0434 0.0784
Schistosoma mansoni rab6-interacting 0.0058 0.0325 0.0321
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0091 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0457
Schistosoma mansoni lamin 0.008 0.0483 0.0479
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0098 0.0618 0.1911
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.016 0.0352
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0073 0.0434 0.043
Schistosoma mansoni thyroid hormone receptor 0.002 0.0045 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Echinococcus multilocularis musashi 0.008 0.0483 0.0483
Schistosoma mansoni DNA polymerase eta 0.0038 0.0179 0.0175
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0118 0.0353
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0325 0.0325
Echinococcus granulosus 7tm_1 domain containing protein 0.0073 0.0434 0.0434
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.002 0.002
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0098 0.0618 0.2542
Mycobacterium tuberculosis Probable dehydrogenase 0.0098 0.0618 0.1882
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0028 0.0106 0.0106
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.0434 0.043
Echinococcus granulosus neuropeptide Y receptor 0.0073 0.0434 0.0434
Leishmania major hypothetical protein, conserved 0.0098 0.0618 0.064
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0179 0.0174
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Schistosoma mansoni neuropeptide receptor 0.0073 0.0434 0.043
Brugia malayi Cytochrome P450 family protein 0.0088 0.0544 0.122
Onchocerca volvulus 0.008 0.0483 0.0883
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Brugia malayi Cyclic-nucleotide gated cation channel 0.0022 0.0056 0.0117
Loa Loa (eye worm) hypothetical protein 0.0104 0.066 0.1489
Schistosoma mansoni biogenic amine (5HT) receptor 0.0438 0.3113 0.311
Schistosoma mansoni hypothetical protein 0.0047 0.0244 0.0239
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0045 0.0045
Brugia malayi Blistered cuticle protein 3 0.007 0.0414 0.0926
Schistosoma mansoni amine GPCR 0.0412 0.2926 0.2923
Loa Loa (eye worm) hypothetical protein 0.0247 0.1716 0.3873
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0045 0.0092
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.037 0.2616 0.2716
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0244 0.0244
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.0129 0.0355
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0073 0.0434 0.0434
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.016 0.016
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.009 0.0555 0.0566
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0037 0.0168 0.038
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0016 0.0004
Loa Loa (eye worm) histone methyltransferase 0.002 0.0047 0.0106
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.0129 0.0355
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0098 0.0618 0.1856
Echinococcus granulosus neuropeptide receptor 0.0073 0.0434 0.0434
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.018 0.018
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0073 0.0434 0.0434
Onchocerca volvulus 0.0073 0.0434 0.0784
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0073 0.0434 0.097
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0266 0.0814
Loa Loa (eye worm) blistered cuticle protein 3 0.007 0.0414 0.0934
Loa Loa (eye worm) TYRA-2 protein 0.0073 0.0434 0.0979
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0555 0.106
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0098 0.0618 0.0633
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0367 0.147
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0179 0.0175
Brugia malayi Pre-SET motif family protein 0.009 0.0555 0.1244
Brugia malayi putative neuropeptide receptor NPR1 0.0073 0.0434 0.097
Mycobacterium ulcerans ferredoxin reductase 0.0098 0.0618 0.1856
Schistosoma mansoni hypothetical protein 0.0098 0.0618 0.0615
Onchocerca volvulus 0.0096 0.0603 0.1122
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0671 0.483 0.9551
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0457
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0022 0.0055 0.0116
Echinococcus multilocularis dro:myosuppressin receptor 0.0073 0.0434 0.0434
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0071 0.0421 0.0426
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.004 0.0006
Echinococcus granulosus geminin 0.0338 0.2378 0.2378
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.004 0.0081
Echinococcus granulosus g-protein coupled receptor 0.0073 0.0434 0.0434
Echinococcus granulosus sex peptide receptor 0.0073 0.0434 0.0434
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1111 0.8061 0.8398
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.0129 0.0355
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0022 0.0055 0.0053
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0098 0.0618 0.2542
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.0129 0.0291
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.037 0.2616 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.037 0.2616 0.2613
Brugia malayi protein-tyrosine kinase 0.0035 0.0152 0.0335
Onchocerca volvulus Neuropeptide F receptor homolog 0.0073 0.0434 0.0784
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0206 0.0206
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0092 0.0573 0.0569
Schistosoma mansoni hypothetical protein 0.0047 0.0244 0.0239
Loa Loa (eye worm) glutathione reductase 0.0452 0.3219 0.7265
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.0129 0.0355
Loa Loa (eye worm) programmed cell death 8 0.0098 0.0618 0.1396
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0037 0.017 0.0165
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0073 0.0434 0.0434
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0206 0.0202
Loa Loa (eye worm) hypothetical protein 0.0078 0.0472 0.1066
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0098 0.0618 0.1856
Loa Loa (eye worm) norepinephrine transporter 0.0247 0.1716 0.3873
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0971 0.2984
Leishmania major hypothetical protein, conserved 0.0098 0.0618 0.064
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.016 0.0154
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi CXXC zinc finger family protein 0.0056 0.0305 0.068
Brugia malayi Thioredoxin reductase 0.0452 0.3219 0.7262
Echinococcus multilocularis serotonin receptor 0.0198 0.135 0.135
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0098 0.0618 0.1186
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0206 0.0202
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.0643 0.0658
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0643 0.0658
Echinococcus granulosus g protein coupled receptor 0.0073 0.0434 0.0434
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0118 0.0308
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0367 0.037
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0016 0.0012
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0106 0.0106
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.009 0.0555 0.0555
Schistosoma mansoni coup transcription factor 0.002 0.0045 0.0041
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0025 0.0008
Plasmodium vivax multidomain scavenger receptor, putative 0.0058 0.0325 0.0967
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0085 0.052 0.0516
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0085 0.052 0.1165
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0715 0.1377
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.0643 0.0666
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0042 0.0208 0.0205
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trypanosoma cruzi cytochrome P450, putative 0.0049 0.0258 0.0256
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0101
Schistosoma mansoni intermediate filament proteins 0.008 0.0483 0.0479
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.037 0.2616 0.8117
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0098 0.0618 0.0633
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0117 0.0113
Trypanosoma brucei protein kinase, putative 0.0101 0.0643 0.0658
Leishmania major hypothetical protein, conserved 0.0016 0.0012 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0787 0.0783
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0098 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.037 0.2616 0.8124
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0117 0.0117
Loa Loa (eye worm) thioredoxin reductase 0.0452 0.3219 0.7265
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0016 0.0016
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.009 0.0555 0.0566
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.037 0.2616 0.59
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0715 0.2182
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.0129 0.0122
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0008
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0098 0.0618 0.1882
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0045 0.0101
Toxoplasma gondii NADPH-glutathione reductase 0.037 0.2616 0.8124
Loa Loa (eye worm) hypothetical protein 0.0377 0.2667 0.602
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0056 0.0052
Echinococcus multilocularis lamin dm0 0.008 0.0483 0.0483
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0037 0.0168 0.0292
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0206 0.0464
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.0434 0.0434
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.037 0.2616 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0021 0.001
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0098 0.0618 0.0618
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0098 0.0618 0.0618
Schistosoma mansoni cpg binding protein 0.0061 0.0343 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.1735 0.3404
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.025 0.1735 0.3915
Echinococcus granulosus dro:myosuppressin receptor 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Schistosoma mansoni hypothetical protein 0.0073 0.0434 0.043
Loa Loa (eye worm) hypothetical protein 0.0042 0.0206 0.0464
Brugia malayi G-protein coupled receptor 0.0073 0.0434 0.097
Leishmania major hypothetical protein, conserved 0.0098 0.0618 0.064
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0056 0.0069
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0037 0.0168 0.0626
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0715 0.1613
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.0643 0.0658
Brugia malayi Serotonin receptor 0.0073 0.0434 0.097
Brugia malayi AKH receptor 0.0073 0.0434 0.097
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0617 0.4431 1
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0037 0.0168 0.0171
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0316 0.2223 0.6987
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.2096 0.7983
Brugia malayi N-terminal motif family protein 0.0194 0.1326 0.2987
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.0129 0.013
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.0643 0.0643
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0179 0.0174
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0073 0.0431 0.0813
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0179 0.045
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0055 0.0045
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0438 0.3113 0.3113
Echinococcus granulosus neuropeptide receptor A26 0.0518 0.3708 0.3708
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.1103 0.2148
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0715 0.0715
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0022 0.0055 0.0055
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.009 0.0555 0.0566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0073 0.0103
Echinococcus multilocularis serotonin receptor 0.0198 0.135 0.135
Loa Loa (eye worm) hypothetical protein 0.0058 0.0325 0.0735
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0098 0.0618 0.0633
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.016 0.0162
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0045 0.0101
Toxoplasma gondii thioredoxin reductase 0.0452 0.3219 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0073 0.0434 0.0434
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.0129 0.0291
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0194 0.1326 0.2564
Brugia malayi phosphofructokinase 0.0111 0.0715 0.1605
Trypanosoma brucei trypanothione reductase 0.0452 0.3219 0.3346
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0056 0.0056
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0098 0.0618 0.1882
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0643 0.1235
Mycobacterium tuberculosis Probable oxidoreductase 0.037 0.2616 0.8117
Schistosoma mansoni alpha-1 adrenergic receptor 0.0073 0.0434 0.043
Mycobacterium ulcerans flavoprotein disulfide reductase 0.037 0.2616 0.8245
Schistosoma mansoni hypothetical protein 0.0338 0.2378 0.2374
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0107 0.0683 0.1542
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0179 0.051
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.0129 0.0291
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0106 0.0101
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.037 0.2616 0.8124
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0045 0.0092
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0212 0.0208
Loa Loa (eye worm) hypothetical protein 0.0067 0.0389 0.0877
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.008
Brugia malayi putative neuropeptide receptor 0.0073 0.0434 0.097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0075 0.0107
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0337 0.2371 1
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0016 0.0026
Echinococcus granulosus neuropeptides capa receptor 0.0073 0.0434 0.0434
Loa Loa (eye worm) TK protein kinase 0.0031 0.0124 0.028
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0091
Brugia malayi isocitrate dehydrogenase 0.0016 0.0016 0.0026
Schistosoma mansoni hypothetical protein 0.0047 0.0244 0.0239
Brugia malayi hypothetical protein 0.0073 0.0434 0.097
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0049 0.0258 0.0701
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0032 0.0022
Loa Loa (eye worm) hypothetical protein 0.0047 0.0241 0.0544
Schistosoma mansoni ap endonuclease 0.0019 0.0038 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0045 0.0045
Schistosoma mansoni biogenic amine (5HT) receptor 0.0198 0.135 0.1346
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.0129 0.0291
Brugia malayi ORL1-like opioid receptor 0.0073 0.0434 0.097
Echinococcus multilocularis G-protein coupled receptor, putative 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Brugia malayi M-phase phosphoprotein, mpp8 0.0104 0.0659 0.1479
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.0643 0.0643
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0117 0.0117
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0098 0.0618 0.0618
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0367 0.0378
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.0434 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0045 0.0092
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0117 0.0118
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0073 0.0434 0.0434
Loa Loa (eye worm) hypothetical protein 0.0098 0.0618 0.1396
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0098 0.0618 0.0618
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0073 0.0434 0.097
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.0129 0.0355
Leishmania major cytochrome p450-like protein 0.0049 0.0258 0.0264
Echinococcus granulosus intermediate filament protein 0.008 0.0483 0.0483
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.0129 0.0355
Trypanosoma brucei NADH dehydrogenase 0.0098 0.0618 0.0633
Schistosoma mansoni adenoreceptor 0.0073 0.0434 0.043
Loa Loa (eye worm) hypothetical protein 0.0376 0.2659 0.6001
Treponema pallidum quinoline 2-oxidoreductase 0.0107 0.068 0.249
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0145 0.0145
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0206 0.0206
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.009 0.0555 0.227
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0244 0.055
Schistosoma mansoni glutamate synthase 0.0098 0.0618 0.0615
Treponema pallidum thioredoxin reductase (trxB) 0.0098 0.0618 0.2251
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0039 0.018 0.018
Echinococcus granulosus somatostatin receptor 0.0073 0.0434 0.0434
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.1168 0.2277
Echinococcus multilocularis sex peptide receptor 0.0073 0.0434 0.0434
Echinococcus multilocularis somatostatin receptor 0.0073 0.0434 0.0434
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0211 0.0467
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0098 0.0618 0.2245
Echinococcus granulosus cGMP dependent protein kinase 0.0015 0.0004 0.0004
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0092 0.0573 0.0573
Schistosoma mansoni neuropeptide F-like receptor 0.0073 0.0434 0.043
Echinococcus multilocularis microtubule associated protein 2 0.1375 1 1
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0098 0.0618 0.0618
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0037 0.0168 0.0168
Echinococcus granulosus RUN 0.0058 0.0325 0.0325
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0022 0.0055 0.0125
Loa Loa (eye worm) hypothetical protein 0.0073 0.0434 0.0979
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0206 0.0202
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0016 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.025 0.1735 0.3404
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0117 0.0256
Loa Loa (eye worm) hypothetical protein 0.0085 0.052 0.1173
Loa Loa (eye worm) hypothetical protein 0.0376 0.2659 0.6001
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.016 0.016
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0022 0.0055 0.0124
Echinococcus multilocularis g protein coupled receptor 0.0073 0.0434 0.0434
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.0434 0.043
Trypanosoma cruzi adrenodoxin precursor, putative 0.0022 0.0055 0.0045
Loa Loa (eye worm) hypothetical protein 0.0028 0.0106 0.0238
Brugia malayi steroid hormone receptor 0.002 0.0045 0.0092
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.004 0.0077
Onchocerca volvulus 0.0099 0.0621 0.1157
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0168 0.0476
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2096 0.4121
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.016 0.0154
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0056 0.0056
Onchocerca volvulus 0.0073 0.0434 0.0784
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.0129 0.0291
Schistosoma mansoni tyrosine kinase 0.0039 0.018 0.0176
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0038 0.0034
Trypanosoma brucei unspecified product 0.0038 0.0179 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0252 0.0458
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.0129 0.0355
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0244 0.0541
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.0683 0.0679
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0022 0.0055 0.0116
Toxoplasma gondii ferodoxin FD 0.0022 0.0055 0.0159
Loa Loa (eye worm) melatonin receptor type 1A 0.0073 0.0434 0.0979
Trichomonas vaginalis Ferredoxin 7 0.0022 0.0055 0.0068
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0442 0.1561
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0206 0.0206
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0073 0.0434 0.097
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0106 0.0106
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0039 0.018 0.018
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0004 0.0004
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0118 0.0353
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0206 0.0206
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.016 0.0276
Trypanosoma cruzi NADH dehydrogenase, putative 0.0098 0.0618 0.0633
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0038 0.0073
Schistosoma mansoni 60S ribosomal protein L21 0.0015 0.0005 0.0001
Brugia malayi 6-phosphofructokinase 0.0111 0.0715 0.1605
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0022 0.0055 0.0066
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0038 0.0036
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0073 0.0434 0.0434
Trypanosoma brucei hypothetical protein, conserved 0.0098 0.0618 0.0633
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0037 0.0168 0.0511
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0117 0.0191
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0098 0.0618 0.2251

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) NT 0 mg kg-1 Effective dose administered perorally against Forest virus infected mice ChEMBL. 2999405
ED50 (functional) NT 0 mg kg-1 Effective dose administered subcutaneously against Forest virus infected mice ChEMBL. 2999405
ED50 (functional) > 400 mg kg-1 Antiviral activity against Forest virus (SFV) ChEMBL. 2999405
Protection index (functional) = 0 Intraperitoneal administration against herpes simplex virus type-1 (HSV-1) infected mice ChEMBL. 2999405

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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